메뉴 건너뛰기




Volumn 70, Issue 12, 2010, Pages 5034-5045

Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 24; PROTEIN BAK; PROTEIN MCL 1;

EID: 77953805572     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-0563     Document Type: Article
Times cited : (69)

References (40)
  • 1
    • 43449127502 scopus 로고    scopus 로고
    • Prostate cancer
    • Damber JE, Aus G. Prostate cancer. Lancet 2008;371:1710-21.
    • (2008) Lancet , vol.371 , pp. 1710-1721
    • Damber, J.E.1    Aus, G.2
  • 2
    • 0036324470 scopus 로고    scopus 로고
    • Gene therapy of prostate cancer: Current and future directions
    • Mabjeesh NJ, Zhong H, Simons JW. Gene therapy of prostate cancer: current and future directions. Endocr Relat Cancer 2002;9:115-39.
    • (2002) Endocr Relat Cancer , vol.9 , pp. 115-139
    • Mabjeesh, N.J.1    Zhong, H.2    Simons, J.W.3
  • 3
    • 0029558740 scopus 로고
    • Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression
    • Jiang H, Lin JJ, Su ZZ, Goldstein NI, Fisher PB. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene 1995;11:2477-86.
    • (1995) Oncogene , vol.11 , pp. 2477-2486
    • Jiang, H.1    Lin, J.J.2    Su, Z.Z.3    Goldstein, N.I.4    Fisher, P.B.5
  • 6
    • 19944384118 scopus 로고    scopus 로고
    • Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanomadifferentiation associated gene-7 (mda-7/IL24): Biologic outcome in advanced cancer patients
    • Tong AW, Nemunaitis J, Su D, et al. Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanomadifferentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients. Mol Ther 2005;11:160-72.
    • (2005) Mol Ther , vol.11 , pp. 160-172
    • Tong, A.W.1    Nemunaitis, J.2    Su, D.3
  • 7
    • 66149138884 scopus 로고    scopus 로고
    • Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24
    • Emdad L, Lebedeva IV, Su ZZ, et al. Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24. Cancer Biol Ther 2009;8:391-400.
    • (2009) Cancer Biol Ther , vol.8 , pp. 391-400
    • Emdad, L.1    Lebedeva, I.V.2    Su, Z.Z.3
  • 8
    • 28544435618 scopus 로고    scopus 로고
    • Is mda-7/IL-24 a "magic bullet" for cancer?
    • Fisher PB. Is mda-7/IL-24 a "magic bullet" for cancer? Cancer Res 2005;65:10128-38.
    • (2005) Cancer Res , vol.65 , pp. 10128-10138
    • Fisher, P.B.1
  • 9
    • 38449096542 scopus 로고    scopus 로고
    • mda-7/IL-24, novel anticancer cytokine: Focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience
    • Review
    • Lebedeva IV, Emdad L, Su ZZ, et al. mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review). Int J Oncol 2007;31:985-1007.
    • (2007) Int J Oncol , vol.31 , pp. 985-1007
    • Lebedeva, I.V.1    Emdad, L.2    Su, Z.Z.3
  • 10
    • 33846205598 scopus 로고    scopus 로고
    • N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity
    • Sauane M, Gupta P, Lebedeva IV, et al. N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity. Cancer Res 2006;66:11869-77.
    • (2006) Cancer Res , vol.66 , pp. 11869-11877
    • Sauane, M.1    Gupta, P.2    Lebedeva, I.V.3
  • 11
    • 34248156775 scopus 로고    scopus 로고
    • Melanoma differentiation associated gene-7 (mda-7)/IL-24: A 'magic bullet' for cancer therapy?
    • Sarkar D, Lebedeva IV, Gupta P, et al. Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy? Expert Opin Biol Ther 2007;7:577-86.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 577-586
    • Sarkar, D.1    Lebedeva, I.V.2    Gupta, P.3
  • 12
    • 33746257314 scopus 로고    scopus 로고
    • Melanoma differentiation-associated gene-7 (mda-7)/interleukin (IL)-24 induces anticancer immunity in a syngeneic murine model
    • Miyahara R, Banerjee S, Kawano K, et al. Melanoma differentiation- associated gene-7 (mda-7)/interleukin (IL)-24 induces anticancer immunity in a syngeneic murine model. Cancer Gene Ther 2006;13:753-61.
    • (2006) Cancer Gene Ther , vol.13 , pp. 753-761
    • Miyahara, R.1    Banerjee, S.2    Kawano, K.3
  • 13
    • 45549098748 scopus 로고    scopus 로고
    • Secretable chaperone Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24
    • Gao P, Sun X, Chen X, et al. Secretable chaperone Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24. Cancer Res 2008;68:3890-8.
    • (2008) Cancer Res , vol.68 , pp. 3890-3898
    • Gao, P.1    Sun, X.2    Chen, X.3
  • 14
    • 27844459421 scopus 로고    scopus 로고
    • Unique aspects of mda-7/IL-24 antitumor bystander activity: Establishing a role for secretion of MDA-7/IL-24 protein by normal cells
    • Su Z, Emdad L, Sauane M, et al. Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells. Oncogene 2005;24:7552-66.
    • (2005) Oncogene , vol.24 , pp. 7552-7566
    • Su, Z.1    Emdad, L.2    Sauane, M.3
  • 15
    • 7044268950 scopus 로고    scopus 로고
    • Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein
    • Sauane M, Gopalkrishnan RV, Choo HT, et al. Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein. Oncogene 2004;23:7679-90.
    • (2004) Oncogene , vol.23 , pp. 7679-7690
    • Sauane, M.1    Gopalkrishnan, R.V.2    Choo, H.T.3
  • 16
    • 0346365376 scopus 로고    scopus 로고
    • Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species
    • Lebedeva IV, Su ZZ, Sarkar D, et al. Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species. Cancer Res 2003;63:8138-44.
    • (2003) Cancer Res , vol.63 , pp. 8138-8144
    • Lebedeva, I.V.1    Su, Z.Z.2    Sarkar, D.3
  • 17
    • 47749102962 scopus 로고    scopus 로고
    • Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis
    • Sauane M, Su ZZ, Gupta P, et al. Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis. Proc Natl Acad Sci U S A 2008;105:9763-8.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 9763-9768
    • Sauane, M.1    Su, Z.Z.2    Gupta, P.3
  • 18
    • 33748084010 scopus 로고    scopus 로고
    • BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis
    • Gupta P, Walter MR, Su ZZ, et al. BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis. Cancer Res 2006;66:8182-91.
    • (2006) Cancer Res , vol.66 , pp. 8182-8191
    • Gupta, P.1    Walter, M.R.2    Su, Z.Z.3
  • 19
    • 2342557922 scopus 로고    scopus 로고
    • Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways
    • Sauane M, Lebedeva IV, Su ZZ, et al. Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways. Cancer Res 2004;64:2988-93.
    • (2004) Cancer Res , vol.64 , pp. 2988-2993
    • Sauane, M.1    Lebedeva, I.V.2    Su, Z.Z.3
  • 20
    • 0037162507 scopus 로고    scopus 로고
    • Mda-7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK
    • Sarkar D, Su ZZ, Lebedeva IV, et al. mda-7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK. Proc Natl Acad Sci U S A 2002;99:10054-9.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 10054-10059
    • Sarkar, D.1    Su, Z.Z.2    Lebedeva, I.V.3
  • 21
    • 0035144493 scopus 로고    scopus 로고
    • Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
    • McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 2001;21:1249-59.
    • (2001) Mol Cell Biol , vol.21 , pp. 1249-1259
    • McCullough, K.D.1    Martindale, J.L.2    Klotz, L.O.3    Aw, T.Y.4    Holbrook, N.J.5
  • 22
    • 34547949167 scopus 로고    scopus 로고
    • Translational repression of MCL-1 couples stress-induced eIF2α phosphorylation to mitochondrial apoptosis initiation
    • Fritsch RM, Schneider G, Saur D, Scheibel M, Schmid RM. Translational repression of MCL-1 couples stress-induced eIF2α phosphorylation to mitochondrial apoptosis initiation. J Biol Chem 2007;282:22551-62.
    • (2007) J Biol Chem , vol.282 , pp. 22551-22562
    • Fritsch, R.M.1    Schneider, G.2    Saur, D.3    Scheibel, M.4    Schmid, R.M.5
  • 23
    • 0029919668 scopus 로고    scopus 로고
    • Immunohistochemical analysis of bcl-2, bax, bcl-X, mcl-1 expression in prostate cancers
    • Krajewska M, Krajewski S, Epstein JI, et al. Immunohistochemical analysis of bcl-2, bax, bcl-X, mcl-1 expression in prostate cancers. Am J Pathol 1996;148:1567-76.
    • (1996) Am J Pathol , vol.148 , pp. 1567-1576
    • Krajewska, M.1    Krajewski, S.2    Epstein, J.I.3
  • 24
    • 0034283981 scopus 로고    scopus 로고
    • Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells
    • Moulding DA, Giles RV, Spiller DG, White MR, Tidd DM, Edwards SW. Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells. Blood 2000;96:1756-63.
    • (2000) Blood , vol.96 , pp. 1756-1763
    • Moulding, D.A.1    Giles, R.V.2    Spiller, D.G.3    White, M.R.4    Tidd, D.M.5    Edwards, S.W.6
  • 25
    • 0038046166 scopus 로고    scopus 로고
    • Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
    • Nijhawan D, Fang M, Traer E, et al. Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation. Genes Dev 2003;17:1475-86.
    • (2003) Genes Dev , vol.17 , pp. 1475-1486
    • Nijhawan, D.1    Fang, M.2    Traer, E.3
  • 26
    • 0031034078 scopus 로고    scopus 로고
    • Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions
    • Zhou P, Qian L, Kozopas KM, Craig RW. Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions. Blood 1997;89:630-43.
    • (1997) Blood , vol.89 , pp. 630-643
    • Zhou, P.1    Qian, L.2    Kozopas, K.M.3    Craig, R.W.4
  • 27
    • 0345732497 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24
    • Lebedeva IV, Sarkar D, Su ZZ, et al. Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24. Oncogene 2003;22:8758-73.
    • (2003) Oncogene , vol.22 , pp. 8758-8773
    • Lebedeva, I.V.1    Sarkar, D.2    Su, Z.Z.3
  • 28
    • 33846674886 scopus 로고    scopus 로고
    • Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation
    • Chen S, Dai Y, Harada H, Dent P, Grant S. Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation. Cancer Res 2007;67:782-91.
    • (2007) Cancer Res , vol.67 , pp. 782-791
    • Chen, S.1    Dai, Y.2    Harada, H.3    Dent, P.4    Grant, S.5
  • 30
    • 27444436166 scopus 로고    scopus 로고
    • Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation
    • Rahmani M, Davis EM, Bauer C, Dent P, Grant S. Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation. J Biol Chem 2005;280:35217-27.
    • (2005) J Biol Chem , vol.280 , pp. 35217-35227
    • Rahmani, M.1    Davis, E.M.2    Bauer, C.3    Dent, P.4    Grant, S.5
  • 31
    • 34547197343 scopus 로고    scopus 로고
    • The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress
    • Rahmani M, Davis EM, Crabtree TR, et al. The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress. Mol Cell Biol 2007;27:5499-513.
    • (2007) Mol Cell Biol , vol.27 , pp. 5499-5513
    • Rahmani, M.1    Davis, E.M.2    Crabtree, T.R.3
  • 32
    • 0029447034 scopus 로고
    • Methods for isolation and analysis of polyribosomes
    • Davies E, Abe S. Methods for isolation and analysis of polyribosomes. Methods Cell Biol 1995;50:209-22.
    • (1995) Methods Cell Biol , vol.50 , pp. 209-222
    • Davies, E.1    Abe, S.2
  • 33
    • 77953694468 scopus 로고    scopus 로고
    • Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells
    • Epub ahead of print
    • Dash R, Dmetriev I, Su ZZ, et al. Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells. Cancer Gene Ther 2010. [Epub ahead of print].
    • (2010) Cancer Gene Ther
    • Dash, R.1    Dmetriev, I.2    Su, Z.Z.3
  • 34
    • 2342553892 scopus 로고    scopus 로고
    • Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex
    • Leu JI, Dumont P, Hafey M, Murphy ME, George DL. Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex. Nat Cell Biol 2004;6:443-50.
    • (2004) Nat Cell Biol , vol.6 , pp. 443-450
    • Leu, J.I.1    Dumont, P.2    Hafey, M.3    Murphy, M.E.4    George, D.L.5
  • 35
    • 22244464818 scopus 로고    scopus 로고
    • Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
    • Willis SN, Chen L, Dewson G, et al. Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes Dev 2005;19:1294-305.
    • (2005) Genes Dev , vol.19 , pp. 1294-1305
    • Willis, S.N.1    Chen, L.2    Dewson, G.3
  • 36
    • 28244442462 scopus 로고    scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in human disease
    • DOI 10.1111/j.1365-2796.2005.01570.x
    • Fadeel B, Orrenius S. Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease. J Intern Med 2005;258:479-517. (Pubitemid 41705391)
    • (2005) Journal of Internal Medicine , vol.258 , Issue.6 , pp. 479-517
    • Fadeel, B.1    Orrenius, S.2
  • 37
    • 26444442450 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: Cell life and death decisions
    • Xu C, Bailly-Maitre B, Reed JC. Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 2005;115:2656-64.
    • (2005) J Clin Invest , vol.115 , pp. 2656-2664
    • Xu, C.1    Bailly-Maitre, B.2    Reed, J.C.3
  • 38
    • 45349109398 scopus 로고    scopus 로고
    • MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors
    • Yacoub A, Hamed H, Emdad L, et al. MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors. Cancer Biol Ther 2008;7:917-33.
    • (2008) Cancer Biol Ther , vol.7 , pp. 917-933
    • Yacoub, A.1    Hamed, H.2    Emdad, L.3
  • 40
    • 21644432943 scopus 로고    scopus 로고
    • Eukaryotic translation initiation factor 4E is a cellular target for toxicity and death due to exposure to cadmium chloride
    • Othumpangat S, Kashon M, Joseph P. Eukaryotic translation initiation factor 4E is a cellular target for toxicity and death due to exposure to cadmium chloride. J Biol Chem 2005;280:25162-9.
    • (2005) J Biol Chem , vol.280 , pp. 25162-25169
    • Othumpangat, S.1    Kashon, M.2    Joseph, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.