Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma

Molecular Therapy

Volumn 18, Issue 6, 2010, Pages 1130-1142

  Hamed, Hossein A ^a   Yacoub, Adly ^a   Park, Margaret A ^a   Eulitt, Patrick J ^a   Dash, Rupesh ^a   Sarkar, Devanand ^a   Dmitriev, Igor P ^b   Lesniak, MacIej S ^c   Shah, Khalid ^d   Grant, Steven ^a   Curiel, David T ^b   Fisher, Paul B ^a   Dent, Paul ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; HEAT SHOCK PROTEIN 90; INTERLEUKIN 24; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TANESPIMYCIN; INTERLEUKIN DERIVATIVE; INTERLEUKIN-24;

ADENOVIRUS 5; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CELL PROTECTION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GLIOBLASTOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN SYNTHESIS INHIBITION; SEROTYPE; SIGNAL TRANSDUCTION; TREATMENT OUTCOME; TUMOR XENOGRAFT; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT; ADENOVIRIDAE; BRAIN NEOPLASMS; GENE VECTOR; GENETICS; METABOLISM;

ADENOVIRIDAE; BRAIN NEOPLASMS; GENETIC VECTORS; GLIOBLASTOMA; HUMANS; INTERLEUKINS; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

ADENOVIRIDAE; ANIMALIA; MAMMALIA;

EID: 77953134322     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2010.29     Document Type: Article

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