메뉴 건너뛰기




Volumn 15, Issue 5, 2008, Pages 293-302

A cancer terminator virus eradicates both primary and distant human melanomas

Author keywords

Apoptosis; Cancer terminator virus (CTV); mda 7 IL 24; Metastatic melanoma; PEG 3 promoter

Indexed keywords

INTERLEUKIN 24;

EID: 41949127542     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2008.14     Document Type: Article
Times cited : (56)

References (53)
  • 2
    • 0031660951 scopus 로고    scopus 로고
    • Issues in the epidemiology of melanoma
    • Weinstock MA. Issues in the epidemiology of melanoma. Hematol Oncol Clin North Am 1998; 12: 681-698.
    • (1998) Hematol Oncol Clin North Am , vol.12 , pp. 681-698
    • Weinstock, M.A.1
  • 3
    • 0025102645 scopus 로고
    • Human melanoma: Development and progression
    • Herlyn M. Human melanoma: development and progression. Cancer Metastasis Rev 1990; 9: 101-112.
    • (1990) Cancer Metastasis Rev , vol.9 , pp. 101-112
    • Herlyn, M.1
  • 4
    • 0033837128 scopus 로고    scopus 로고
    • Malignant melanoma: Prevention, early detection,and treatment in the 21st century
    • Rigel DS, Carucci JA. Malignant melanoma: prevention, early detection,and treatment in the 21st century. CA Cancer J Clin 2000; 50: 215-236.
    • (2000) CA Cancer J Clin , vol.50 , pp. 215-236
    • Rigel, D.S.1    Carucci, J.A.2
  • 5
    • 0003181212 scopus 로고
    • Diagnosis and treatment of early melanoma
    • Diagnosis and treatment of early melanoma. NIH Consens Statement 1992; 10: 1-26.
    • (1992) NIH Consens Statement , vol.10 , pp. 1-26
  • 6
    • 0029558740 scopus 로고
    • Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation,growth and progression
    • Jiang H, Lin JJ, Su ZZ, Goldstein NI, Fisher PB. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation,growth and progression. Oncogene 1995; 11: 2477-2486.
    • (1995) Oncogene , vol.11 , pp. 2477-2486
    • Jiang, H.1    Lin, J.J.2    Su, Z.Z.3    Goldstein, N.I.4    Fisher, P.B.5
  • 7
    • 0035950553 scopus 로고    scopus 로고
    • Genomic structure,chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties
    • Huang EY, Madireddi MT, Gopalkrishnan RV, Leszczyniecka M, Su ZZ, Lebedeva IV et al. Genomic structure,chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties. Oncogene 2001; 20: 7051-7063.
    • (2001) Oncogene , vol.20 , pp. 7051-7063
    • Huang, E.Y.1    Madireddi, M.T.2    Gopalkrishnan, R.V.3    Leszczyniecka, M.4    Su, Z.Z.5    Lebedeva, I.V.6
  • 10
    • 0032564357 scopus 로고    scopus 로고
    • The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice
    • Su ZZ, Madireddi MT, Lin JJ, Young CSH, Kitada S, Reed JC et al. The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice. Proc Natl Acad Sci USA 1998; 95: 14400-14405.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14400-14405
    • Su, Z.Z.1    Madireddi, M.T.2    Lin, J.J.3    Young, C.S.H.4    Kitada, S.5    Reed, J.C.6
  • 11
    • 85047695547 scopus 로고    scopus 로고
    • The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells
    • Lebedeva IV, Su ZZ, Chang Y, Kitada S, Reed JC, Fisher PB. The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells. Oncogene 2002; 21: 708-718.
    • (2002) Oncogene , vol.21 , pp. 708-718
    • Lebedeva, I.V.1    Su, Z.Z.2    Chang, Y.3    Kitada, S.4    Reed, J.C.5    Fisher, P.B.6
  • 12
    • 0037162507 scopus 로고    scopus 로고
    • mda-7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK
    • Sarkar D, Su ZZ, Lebedeva IV, Sauane M, Gopalkrishnan RV, Valerie K et al. mda-7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK. Proc Natl Acad Sci USA 2002; 99: 10054-10059.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10054-10059
    • Sarkar, D.1    Su, Z.Z.2    Lebedeva, I.V.3    Sauane, M.4    Gopalkrishnan, R.V.5    Valerie, K.6
  • 13
    • 34248146982 scopus 로고    scopus 로고
    • Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): Novel gene therapeutic for metastatic melanoma
    • Fisher PB, Sarkar D, Lebedeva IV, Emdad L, Gupta P, Sauane M et al. Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma. Toxicol Appl Pharmacol 2007; 224: 300-307.
    • (2007) Toxicol Appl Pharmacol , vol.224 , pp. 300-307
    • Fisher, P.B.1    Sarkar, D.2    Lebedeva, I.V.3    Emdad, L.4    Gupta, P.5    Sauane, M.6
  • 14
    • 28544435618 scopus 로고    scopus 로고
    • mda-7/IL-24 a 'magic bullet' for cancer?
    • Fisher PB. Is mda-7/IL-24 a 'magic bullet' for cancer? Cancer Res 2005; 65: 10128-10138.
    • (2005) Cancer Res , vol.65 , pp. 10128-10138
    • Fisher, P.I.1
  • 15
  • 17
    • 34248156775 scopus 로고    scopus 로고
    • Melanoma differentiation associated gene-7 (mda-7)/IL-24: A 'magic bullet' for cancer therapy?
    • Sarkar D, Lebedeva IV, Gupta P, Emdad L, Dent P, Curiel DT et al. Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy? Expert Opin Biol Ther 2007; 7: 577-586.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 577-586
    • Sarkar, D.1    Lebedeva, I.V.2    Gupta, P.3    Emdad, L.4    Dent, P.5    Curiel, D.T.6
  • 18
    • 38449096542 scopus 로고    scopus 로고
    • mda-7/IL-24,novel anticancer cytokine: Focus on bystander antitumor,radiosensitization and antiangiogenic properties and overview of the phase I clinical experience
    • Lebedeva IV, Emdad L, Su ZZ, Gupta P, Sauane M, Sarkar D et al. mda-7/IL-24,novel anticancer cytokine: focus on bystander antitumor,radiosensitization and antiangiogenic properties and overview of the phase I clinical experience. Int J Oncol 2007; 31: 985-1007.
    • (2007) Int J Oncol , vol.31 , pp. 985-1007
    • Lebedeva, I.V.1    Emdad, L.2    Su, Z.Z.3    Gupta, P.4    Sauane, M.5    Sarkar, D.6
  • 19
    • 0034475080 scopus 로고    scopus 로고
    • Mda-7,a novel melanoma differentiation associated gene with promise for cancer gene therapy
    • Madireddi MT, Su ZZ, Young CSH, Goldstein NI, Fisher PB. Mda-7,a novel melanoma differentiation associated gene with promise for cancer gene therapy. Adv Exp Med Biol 2000; 465: 239-261.
    • (2000) Adv Exp Med Biol , vol.465 , pp. 239-261
    • Madireddi, M.T.1    Su, Z.Z.2    Young, C.S.H.3    Goldstein, N.I.4    Fisher, P.B.5
  • 21
    • 25444519500 scopus 로고    scopus 로고
    • Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice
    • Sarkar D, Su ZZ, Vozhilla N, Park ES, Gupta P, Fisher PB. Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice. Proc Natl Acad Sci USA 2005; 102: 14034-14039.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 14034-14039
    • Sarkar, D.1    Su, Z.Z.2    Vozhilla, N.3    Park, E.S.4    Gupta, P.5    Fisher, P.B.6
  • 22
    • 0037019174 scopus 로고    scopus 로고
    • Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo
    • Saeki T, Mhashilkar A, Swanson X, Zou-Yang XH, Sieger K, Kawabe S et al. Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo. Oncogene 2002; 21: 4558-4566.
    • (2002) Oncogene , vol.21 , pp. 4558-4566
    • Saeki, T.1    Mhashilkar, A.2    Swanson, X.3    Zou-Yang, X.H.4    Sieger, K.5    Kawabe, S.6
  • 23
    • 0041513362 scopus 로고    scopus 로고
    • Melanoma differentiation-associated gene 7/interleukin (IL)-24 is a novel ligand that regulates angiogenesis via the IL-22 receptor
    • Ramesh R, Mhashilkar AM, Tanaka F, Saito Y, Branch CD, Sieger K et al. Melanoma differentiation-associated gene 7/interleukin (IL)-24 is a novel ligand that regulates angiogenesis via the IL-22 receptor. Cancer Res 2003; 63: 5105-5113.
    • (2003) Cancer Res , vol.63 , pp. 5105-5113
    • Ramesh, R.1    Mhashilkar, A.M.2    Tanaka, F.3    Saito, Y.4    Branch, C.D.5    Sieger, K.6
  • 24
    • 0037468264 scopus 로고    scopus 로고
    • Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression,apoptosis and radiosensitization in malignant gliomas in a p53-independent manner
    • Su ZZ, Lebedeva IV, Sarkar D, Gopalkrishnan RV, Sauane M, Sigmon C et al. Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression,apoptosis and radiosensitization in malignant gliomas in a p53-independent manner. Oncogene 2003; 22: 1164-1180.
    • (2003) Oncogene , vol.22 , pp. 1164-1180
    • Su, Z.Z.1    Lebedeva, I.V.2    Sarkar, D.3    Gopalkrishnan, R.V.4    Sauane, M.5    Sigmon, C.6
  • 25
    • 0037097637 scopus 로고    scopus 로고
    • The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24
    • Caudell EG, Mumm JB, Poindexter N, Ekmekcioglu S, Mhashilkar AM, Yang XH et al. The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24. J Immunol 2002; 168: 6041-6046.
    • (2002) J Immunol , vol.168 , pp. 6041-6046
    • Caudell, E.G.1    Mumm, J.B.2    Poindexter, N.3    Ekmekcioglu, S.4    Mhashilkar, A.M.5    Yang, X.H.6
  • 26
    • 27844459421 scopus 로고    scopus 로고
    • Unique aspects of mda-7/IL-24 antitumor bystander activity: Establishing a role for secretion of MDA-7/IL-24 protein by normal cells
    • Su ZZ, Emdad L, Sauane M, Lebedeva IV, Sarkar D, Gupta P et al. Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells. Oncogene 2005; 24: 7552-7566.
    • (2005) Oncogene , vol.24 , pp. 7552-7566
    • Su, Z.Z.1    Emdad, L.2    Sauane, M.3    Lebedeva, I.V.4    Sarkar, D.5    Gupta, P.6
  • 28
    • 19944379432 scopus 로고    scopus 로고
    • Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: A phase I study
    • Cunningham CC, Chada S, Merritt JA, Tong A, Senzer N, Zhang Y et al. Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: a phase I study. Mol Ther 2005; 11: 149-159.
    • (2005) Mol Ther , vol.11 , pp. 149-159
    • Cunningham, C.C.1    Chada, S.2    Merritt, J.A.3    Tong, A.4    Senzer, N.5    Zhang, Y.6
  • 29
    • 19944384118 scopus 로고    scopus 로고
    • Intratumoral injection of INGN 241,a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): Biologic outcome in advanced cancer patients
    • Tong AW, Nemunaitis J, Su D, Zhang Y, Cunningham C, Senzer N et al. Intratumoral injection of INGN 241,a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients. Mol Ther 2005; 11: 160-172.
    • (2005) Mol Ther , vol.11 , pp. 160-172
    • Tong, A.W.1    Nemunaitis, J.2    Su, D.3    Zhang, Y.4    Cunningham, C.5    Senzer, N.6
  • 30
    • 4544237140 scopus 로고    scopus 로고
    • Current strategies in cancer gene therapy
    • El-Aneed A. Current strategies in cancer gene therapy. Eur J Pharmacol 2004; 498: 1-8.
    • (2004) Eur J Pharmacol , vol.498 , pp. 1-8
    • El-Aneed, A.1
  • 31
    • 0035342191 scopus 로고    scopus 로고
    • Cancer gene therapy by adenovirus-mediated gene transfer
    • Wu Q, Moyana T, Xiang J. Cancer gene therapy by adenovirus-mediated gene transfer. Curr Gene Ther 2001; 1: 101-122.
    • (2001) Curr Gene Ther , vol.1 , pp. 101-122
    • Wu, Q.1    Moyana, T.2    Xiang, J.3
  • 32
    • 0037375977 scopus 로고    scopus 로고
    • Restoring apoptosis as a strategy for cancer gene therapy: Focus on p53 and mda-7
    • Lebedeva IV, Su ZZ, Sarkar D, Fisher PB. Restoring apoptosis as a strategy for cancer gene therapy: focus on p53 and mda-7. Semin Cancer Biol 2003; 13: 169-178.
    • (2003) Semin Cancer Biol , vol.13 , pp. 169-178
    • Lebedeva, I.V.1    Su, Z.Z.2    Sarkar, D.3    Fisher, P.B.4
  • 33
    • 0033926002 scopus 로고    scopus 로고
    • Replicative adenoviruses for cancer therapy
    • Alemany R, Balague C, Curiel DT. Replicative adenoviruses for cancer therapy. Nat Biotechnol 2000; 18: 723-727.
    • (2000) Nat Biotechnol , vol.18 , pp. 723-727
    • Alemany, R.1    Balague, C.2    Curiel, D.T.3
  • 34
    • 0035904982 scopus 로고    scopus 로고
    • Conditional gene targeting for cancer gene therapy
    • Haviv YS, Curiel DT. Conditional gene targeting for cancer gene therapy. Adv Drug Deliv Rev 2001; 53: 135-154.
    • (2001) Adv Drug Deliv Rev , vol.53 , pp. 135-154
    • Haviv, Y.S.1    Curiel, D.T.2
  • 35
    • 0346031707 scopus 로고    scopus 로고
    • Engineering regulatory elements for conditionally-replicative adeno-viruses
    • Haviv YS, Curiel DT. Engineering regulatory elements for conditionally-replicative adeno-viruses. Curr Gene Ther 2003; 3: 357-385.
    • (2003) Curr Gene Ther , vol.3 , pp. 357-385
    • Haviv, Y.S.1    Curiel, D.T.2
  • 36
    • 0037102156 scopus 로고    scopus 로고
    • Novel oncolytic adenoviruses targeted to melanoma: Specific viral replication and cytolysis by expression of E1A mutants from the tyrosinase enhancer/promoter
    • Nettelbeck DM, Rivera AA, Balague C, Alemany R, Curiel DT. Novel oncolytic adenoviruses targeted to melanoma: specific viral replication and cytolysis by expression of E1A mutants from the tyrosinase enhancer/promoter. Cancer Res 2002; 62: 4663-4670.
    • (2002) Cancer Res , vol.62 , pp. 4663-4670
    • Nettelbeck, D.M.1    Rivera, A.A.2    Balague, C.3    Alemany, R.4    Curiel, D.T.5
  • 37
    • 4444354567 scopus 로고    scopus 로고
    • Analyses of melanoma-targeted oncolytic adenoviruses with tyrosinase enhancer/promoter-driven E1A, E4, or both in submerged cells and organotypic cultures
    • Banerjee NS, Rivera AA, Wang M, Chow LT, Broker TR, Curiel DT et al. Analyses of melanoma-targeted oncolytic adenoviruses with tyrosinase enhancer/promoter-driven E1A, E4, or both in submerged cells and organotypic cultures. Mol Cancer Ther 2004; 3: 437-449.
    • (2004) Mol Cancer Ther , vol.3 , pp. 437-449
    • Banerjee, N.S.1    Rivera, A.A.2    Wang, M.3    Chow, L.T.4    Broker, T.R.5    Curiel, D.T.6
  • 38
    • 0032922211 scopus 로고    scopus 로고
    • Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancer
    • Wildner O, Morris JC, Vahanian NN, Ford Jr H, Ramsey WJ, Blaese RM. Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancer. Gene Ther 1999; 6: 57-62.
    • (1999) Gene Ther , vol.6 , pp. 57-62
    • Wildner, O.1    Morris, J.C.2    Vahanian, N.N.3    Ford Jr, H.4    Ramsey, W.J.5    Blaese, R.M.6
  • 39
    • 12844268071 scopus 로고    scopus 로고
    • Targeting gene expression selectively in cancer cells using the progression elevated gene-3 promoter
    • Su ZZ, Sarkar D, Emdad L, Duigou GJ, Young CSH, Ware J et al. Targeting gene expression selectively in cancer cells using the progression elevated gene-3 promoter. Proc Natl Acad Sci USA 2005; 102: 1059-1064.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1059-1064
    • Su, Z.Z.1    Sarkar, D.2    Emdad, L.3    Duigou, G.J.4    Young, C.S.H.5    Ware, J.6
  • 40
    • 25444448484 scopus 로고    scopus 로고
    • Targeted virus replication plus immunotherapy eradicates primary and distant pancreatic tumors in nude mice
    • Sarkar D, Su ZZ, Vozhilla N, Park ES, Randolph A, Valerie K et al. Targeted virus replication plus immunotherapy eradicates primary and distant pancreatic tumors in nude mice. Cancer Res 2005; 65: 9056-9063.
    • (2005) Cancer Res , vol.65 , pp. 9056-9063
    • Sarkar, D.1    Su, Z.Z.2    Vozhilla, N.3    Park, E.S.4    Randolph, A.5    Valerie, K.6
  • 41
    • 34347216741 scopus 로고    scopus 로고
    • Eradication of therapy-resistant human prostate tumors using a cancer terminator virus
    • Sarkar D, Lebedeva IV, Su ZZ, Park ES, Chatman L, Vozhilla N et al. Eradication of therapy-resistant human prostate tumors using a cancer terminator virus. Cancer Res 2007; 67: 5434-5442.
    • (2007) Cancer Res , vol.67 , pp. 5434-5442
    • Sarkar, D.1    Lebedeva, I.V.2    Su, Z.Z.3    Park, E.S.4    Chatman, L.5    Vozhilla, N.6
  • 42
    • 0030812314 scopus 로고    scopus 로고
    • Subtraction hybridization identifies a transformation progression-associated gene PEG-3 with sequence homology to a growth arrest and DNA damage-inducible gene
    • Su ZZ, Shi Y, Fisher PB. Subtraction hybridization identifies a transformation progression-associated gene PEG-3 with sequence homology to a growth arrest and DNA damage-inducible gene. Proc Natl Acad Sci USA 1997; 94: 9125-9130.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9125-9130
    • Su, Z.Z.1    Shi, Y.2    Fisher, P.B.3
  • 43
    • 0033592891 scopus 로고    scopus 로고
    • PEG-3,a nontransforming cancer progression gene,is a positive regulator of cancer aggressiveness and angiogenesis
    • Su ZZ, Goldstein NI, Jiang H, Wang MN, Duigou GJ, Young CSH et al. PEG-3,a nontransforming cancer progression gene,is a positive regulator of cancer aggressiveness and angiogenesis. Proc Natl Acad Sci USA 1999; 96: 15115-15120.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 15115-15120
    • Su, Z.Z.1    Goldstein, N.I.2    Jiang, H.3    Wang, M.N.4    Duigou, G.J.5    Young, C.S.H.6
  • 44
    • 0034644133 scopus 로고    scopus 로고
    • Cooperation between AP1 and PEA3 sites within the progression elevated gene-3 (PEG-3) promoter regulates basal and differential expression of PEG-3 during progression of the oncogenic phenotype in transformed rat embryo cells
    • Su ZZ, Shi Y, Fisher PB. Cooperation between AP1 and PEA3 sites within the progression elevated gene-3 (PEG-3) promoter regulates basal and differential expression of PEG-3 during progression of the oncogenic phenotype in transformed rat embryo cells. Oncogene 2000; 19: 3411-3421.
    • (2000) Oncogene , vol.19 , pp. 3411-3421
    • Su, Z.Z.1    Shi, Y.2    Fisher, P.B.3
  • 45
    • 0035870659 scopus 로고    scopus 로고
    • PEA3 sites within the progression elevated gene-3 (PEG-3) promoter and mitogen-activated protein kinase contribute to differential PEG-3 expression in Ha-ras and v-raf oncogene transformed rat embryo cells
    • Su ZZ, Shi Y, Friedman R, Qiao L, McKinstry R, Hinman D et al. PEA3 sites within the progression elevated gene-3 (PEG-3) promoter and mitogen-activated protein kinase contribute to differential PEG-3 expression in Ha-ras and v-raf oncogene transformed rat embryo cells. Nucleic Acids Res 2001; 29: 1661-1671.
    • (2001) Nucleic Acids Res , vol.29 , pp. 1661-1671
    • Su, Z.Z.1    Shi, Y.2    Friedman, R.3    Qiao, L.4    McKinstry, R.5    Hinman, D.6
  • 46
    • 41949117515 scopus 로고    scopus 로고
    • Cancer terminator viruses (CTV): Unique conditionally replication competent bipartite adenoviruses
    • Hermonat PL ed, Transworld Research Network, in press
    • Sarkar D, Su ZZ, Fisher PB. Cancer terminator viruses (CTV): unique conditionally replication competent bipartite adenoviruses. In: Hermonat PL (ed). Cancer and Gene Therapy, 2007. Transworld Research Network, 2007; in press.
    • (2007) Cancer and Gene Therapy, 2007
    • Sarkar, D.1    Su, Z.Z.2    Fisher, P.B.3
  • 47
    • 33746265063 scopus 로고    scopus 로고
    • Unique conditionally replication competent bipartite adenoviruses - cancer terminator viruses: Efficacious reagents for cancer gene therapy
    • Sarkar D, Su ZZ, Fisher PB. Unique conditionally replication competent bipartite adenoviruses - cancer terminator viruses: efficacious reagents for cancer gene therapy. Cell Cycle 2006; 5: 1531-1536.
    • (2006) Cell Cycle , vol.5 , pp. 1531-1536
    • Sarkar, D.1    Su, Z.Z.2    Fisher, P.B.3
  • 48
    • 0033782862 scopus 로고    scopus 로고
    • An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy
    • Heise C, Hermiston T, Johnson L, Brooks G, Sampson-Johannes A, Williams A et al. An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy. Nat Med 2000; 6: 1134-1139.
    • (2000) Nat Med , vol.6 , pp. 1134-1139
    • Heise, C.1    Hermiston, T.2    Johnson, L.3    Brooks, G.4    Sampson-Johannes, A.5    Williams, A.6
  • 49
    • 19044386714 scopus 로고    scopus 로고
    • Selectively replicating adenoviruses targeting deregulated E2F activity are potent,systemic antitumor agents
    • Johnson L, Shen A, Boyle L, Kunich J, Pandey K, Lemmon M et al. Selectively replicating adenoviruses targeting deregulated E2F activity are potent,systemic antitumor agents. Cancer Cell 2002; 1: 325-337.
    • (2002) Cancer Cell , vol.1 , pp. 325-337
    • Johnson, L.1    Shen, A.2    Boyle, L.3    Kunich, J.4    Pandey, K.5    Lemmon, M.6
  • 50
    • 0141592775 scopus 로고    scopus 로고
    • Ras-dependent oncolysis with an adenovirus VAI mutant
    • Cascallo M, Capella G, Mazo A, Alemany R. Ras-dependent oncolysis with an adenovirus VAI mutant. Cancer Res 2003; 63: 5544-5550.
    • (2003) Cancer Res , vol.63 , pp. 5544-5550
    • Cascallo, M.1    Capella, G.2    Mazo, A.3    Alemany, R.4
  • 52
    • 33746257314 scopus 로고    scopus 로고
    • Melanoma differentiation-associated gene-7 (mda-7)/interleukin (IL)-24 induces anticancer immunity in a syngeneic murine model
    • Miyahara R, Banerjee S, Kawano K, Efferson C, Tsuda N, Miyahara Y et al. Melanoma differentiation-associated gene-7 (mda-7)/interleukin (IL)-24 induces anticancer immunity in a syngeneic murine model. Cancer Gene Ther 2006; 13: 753-761.
    • (2006) Cancer Gene Ther , vol.13 , pp. 753-761
    • Miyahara, R.1    Banerjee, S.2    Kawano, K.3    Efferson, C.4    Tsuda, N.5    Miyahara, Y.6
  • 53
    • 32944474223 scopus 로고    scopus 로고
    • Syrian hamster as a permissive immunocompetent animal model for the study of oncolytic adenovirus vectors
    • Thomas MA, Spencer JF, La Regina MC, Dhar D, Tollefson AE, Toth K et al. Syrian hamster as a permissive immunocompetent animal model for the study of oncolytic adenovirus vectors. Cancer Res 2006; 66: 1270-1276.
    • (2006) Cancer Res , vol.66 , pp. 1270-1276
    • Thomas, M.A.1    Spencer, J.F.2    La Regina, M.C.3    Dhar, D.4    Tollefson, A.E.5    Toth, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.