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Volumn 224, Issue 3, 2007, Pages 300-307

Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): Novel gene therapeutic for metastatic melanoma

Author keywords

Apoptosis; mda 7 IL 24; Metastatic melanoma; Phase I clinical trial

Indexed keywords

ADENOVIRUS VECTOR; INGN 241; INTERLEUKIN 24; UNCLASSIFIED DRUG;

EID: 34248146982     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2006.11.021     Document Type: Review
Times cited : (78)

References (47)
  • 2
    • 21744439869 scopus 로고    scopus 로고
    • Treatment of metastatic malignant melanoma
    • Atallah E., and Flaherty L. Treatment of metastatic malignant melanoma. Curr. Treatm. Opt. Oncol. 6 (2005) 185-193
    • (2005) Curr. Treatm. Opt. Oncol. , vol.6 , pp. 185-193
    • Atallah, E.1    Flaherty, L.2
  • 3
    • 33646252963 scopus 로고    scopus 로고
    • Cytokine-based therapy and biochemotherapy for advanced melanoma
    • Atkins M.B. Cytokine-based therapy and biochemotherapy for advanced melanoma. Clin. Cancer Res. 12 (2006) 2343s-2358s
    • (2006) Clin. Cancer Res. , vol.12
    • Atkins, M.B.1
  • 5
    • 0025909122 scopus 로고
    • Tumor progression and the nature of cancer
    • Clark W.H. Tumor progression and the nature of cancer. Br. J. Cancer 64 (1991) 631-644
    • (1991) Br. J. Cancer , vol.64 , pp. 631-644
    • Clark, W.H.1
  • 6
    • 0037097637 scopus 로고    scopus 로고
    • The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24
    • Caudell E.G., Mumm J.B., Poindexter N., Ekmekcioglu S., Mhashilkar A.M., Yang X.H., Retter M.W., Hill P., Chada S., and Grimm E.A. The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24. J. Immunol. 168 (2002) 6041-6046
    • (2002) J. Immunol. , vol.168 , pp. 6041-6046
    • Caudell, E.G.1    Mumm, J.B.2    Poindexter, N.3    Ekmekcioglu, S.4    Mhashilkar, A.M.5    Yang, X.H.6    Retter, M.W.7    Hill, P.8    Chada, S.9    Grimm, E.A.10
  • 9
    • 33745590474 scopus 로고    scopus 로고
    • Randomized trials in melanoma: an update
    • Eggermont A.M.M. Randomized trials in melanoma: an update. Surg. Oncol. Clin. N. Am. 15 (2006) 439-451
    • (2006) Surg. Oncol. Clin. N. Am. , vol.15 , pp. 439-451
    • Eggermont, A.M.M.1
  • 12
    • 28544435618 scopus 로고    scopus 로고
    • Is mda-7/IL-24 a 'magic bullet' for cancer?
    • Fisher P.B. Is mda-7/IL-24 a 'magic bullet' for cancer?. Cancer Res. 65 (2005) 10128-10138
    • (2005) Cancer Res. , vol.65 , pp. 10128-10138
    • Fisher, P.B.1
  • 13
    • 0021848970 scopus 로고
    • Effects of combined treatment with interferon and mezerein on melanogenesis and growth in human melanoma cells
    • Fisher P.B., Prignoli D.R., Hermo Jr. H., Weinstein I.B., and Pestka S. Effects of combined treatment with interferon and mezerein on melanogenesis and growth in human melanoma cells. J. Interf. Res. 5 (1985) 11-22
    • (1985) J. Interf. Res. , vol.5 , pp. 11-22
    • Fisher, P.B.1    Prignoli, D.R.2    Hermo Jr., H.3    Weinstein, I.B.4    Pestka, S.5
  • 16
    • 33745080277 scopus 로고    scopus 로고
    • Individualized therapy of disseminated cancer using malignant melanoma as a model
    • Hauschild A., Egberts F., Russo P., and Kahler K.C. Individualized therapy of disseminated cancer using malignant melanoma as a model. Cancer Metastasis Rev. 25 (2006) 253-256
    • (2006) Cancer Metastasis Rev. , vol.25 , pp. 253-256
    • Hauschild, A.1    Egberts, F.2    Russo, P.3    Kahler, K.C.4
  • 17
    • 30444432055 scopus 로고    scopus 로고
    • Molecular targets in melanoma: strategies and challenges for diagnosis and therapy
    • Herlyn M. Molecular targets in melanoma: strategies and challenges for diagnosis and therapy. Int. J. Cancer 118 (2006) 523-526
    • (2006) Int. J. Cancer , vol.118 , pp. 523-526
    • Herlyn, M.1
  • 18
    • 0032769247 scopus 로고    scopus 로고
    • Differentiation induction subtraction hybridization (DISH): an approach for cloning genes differentially expressed during growth arrest and terminal differentiation in human melanoma cells
    • Huang F., Adelman J., Jiang H., Goldstein N.I., and Fisher P.B. Differentiation induction subtraction hybridization (DISH): an approach for cloning genes differentially expressed during growth arrest and terminal differentiation in human melanoma cells. Gene 236 (1999) 125-131
    • (1999) Gene , vol.236 , pp. 125-131
    • Huang, F.1    Adelman, J.2    Jiang, H.3    Goldstein, N.I.4    Fisher, P.B.5
  • 20
    • 0027141559 scopus 로고
    • Use of a sensitive and efficient subtraction hybridization protocol for the identification of genes differentially regulated during the induction of differentiation in human melanoma cells
    • Jiang H., and Fisher P.B. Use of a sensitive and efficient subtraction hybridization protocol for the identification of genes differentially regulated during the induction of differentiation in human melanoma cells. Mol. Cell. Differ. 1 (1993) 285-299
    • (1993) Mol. Cell. Differ. , vol.1 , pp. 285-299
    • Jiang, H.1    Fisher, P.B.2
  • 21
    • 0000993733 scopus 로고
    • Gene expression changes associated with reversible growth suppression and the induction of terminal differentiation in human melanoma cells
    • Jiang H., Su Z.-Z., Boyd J., and Fisher P.B. Gene expression changes associated with reversible growth suppression and the induction of terminal differentiation in human melanoma cells. Mol. Cell. Differ. 1 (1993) 41-66
    • (1993) Mol. Cell. Differ. , vol.1 , pp. 41-66
    • Jiang, H.1    Su, Z.-Z.2    Boyd, J.3    Fisher, P.B.4
  • 22
    • 0027951937 scopus 로고
    • A molecular definition of terminal cell differentiation in human melanoma cells
    • Jiang H., Lin J., and Fisher P.B. A molecular definition of terminal cell differentiation in human melanoma cells. Mol. Cell. Differ. 2 (1994) 221-239
    • (1994) Mol. Cell. Differ. , vol.2 , pp. 221-239
    • Jiang, H.1    Lin, J.2    Fisher, P.B.3
  • 23
    • 0029558740 scopus 로고
    • Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression
    • Jiang H., Lin J.J., Su Z.-z., Goldstein N.I., and Fisher P.B. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene 11 (1995) 2477-2486
    • (1995) Oncogene , vol.11 , pp. 2477-2486
    • Jiang, H.1    Lin, J.J.2    Su, Z.-z.3    Goldstein, N.I.4    Fisher, P.B.5
  • 24
    • 0029031949 scopus 로고
    • The melanoma differentiation associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells
    • Jiang H., Lin J., Su Z.-Z., Kerbel R.S., Herlyn M., Weissman R.B., Welch D., and Fisher P.B. The melanoma differentiation associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells. Oncogene 10 (1995) 1855-1864
    • (1995) Oncogene , vol.10 , pp. 1855-1864
    • Jiang, H.1    Lin, J.2    Su, Z.-Z.3    Kerbel, R.S.4    Herlyn, M.5    Weissman, R.B.6    Welch, D.7    Fisher, P.B.8
  • 26
    • 0033748034 scopus 로고    scopus 로고
    • RaSH, a rapid subtraction hybridization approach for identifying and cloning differentially expressed genes
    • Jiang H., Kang D.-c., Alexandre D., and Fisher P.B. RaSH, a rapid subtraction hybridization approach for identifying and cloning differentially expressed genes. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 12684-12689
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 12684-12689
    • Jiang, H.1    Kang, D.-c.2    Alexandre, D.3    Fisher, P.B.4
  • 27
    • 0032506148 scopus 로고    scopus 로고
    • Reciprocal subtraction differential RNA display: an efficient and rapid procedure for isolating differentially expressed gene sequences
    • Kang D.-c., La France R., Su Z.-z., and Fisher P.B. Reciprocal subtraction differential RNA display: an efficient and rapid procedure for isolating differentially expressed gene sequences. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 13788-13793
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 13788-13793
    • Kang, D.-c.1    La France, R.2    Su, Z.-z.3    Fisher, P.B.4
  • 28
    • 0037154176 scopus 로고    scopus 로고
    • mda-5, an interferon-inducible putative RNA helicase with dsRNA-dependent ATPase activity and melanoma growth suppressive properties
    • Kang D.-c., Gopalkrishnan R.V., Wu Q., Jankowsky E., Pyle A.M., and Fisher P.B. mda-5, an interferon-inducible putative RNA helicase with dsRNA-dependent ATPase activity and melanoma growth suppressive properties. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 637-642
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 637-642
    • Kang, D.-c.1    Gopalkrishnan, R.V.2    Wu, Q.3    Jankowsky, E.4    Pyle, A.M.5    Fisher, P.B.6
  • 29
    • 33646254412 scopus 로고    scopus 로고
    • Strategies for the development of more effective adjuvant therapy of melanoma: current and future explorations of antibodies, cytokines, vaccines, and combinations
    • Kirkwood J.M., Moschos S., and Wang W. Strategies for the development of more effective adjuvant therapy of melanoma: current and future explorations of antibodies, cytokines, vaccines, and combinations. Clin. Cancer Res. 12 (2006) 2331s-2336s
    • (2006) Clin. Cancer Res. , vol.12
    • Kirkwood, J.M.1    Moschos, S.2    Wang, W.3
  • 30
    • 85047695547 scopus 로고    scopus 로고
    • The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells
    • Lebedeva I.V., Su Z.-z., Chang Y., Kitada S., Reed J.C., and Fisher P.B. The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells. Oncogene 21 (2002) 708-718
    • (2002) Oncogene , vol.21 , pp. 708-718
    • Lebedeva, I.V.1    Su, Z.-z.2    Chang, Y.3    Kitada, S.4    Reed, J.C.5    Fisher, P.B.6
  • 33
    • 0034816040 scopus 로고    scopus 로고
    • Differentiation therapy of cancer: basic science and clinical applications
    • Leszczyniecka M., Roberts T., Dent P., Grant S., and Fisher P.B. Differentiation therapy of cancer: basic science and clinical applications. Pharmacol. Ther. 90 (2001) 105-156
    • (2001) Pharmacol. Ther. , vol.90 , pp. 105-156
    • Leszczyniecka, M.1    Roberts, T.2    Dent, P.3    Grant, S.4    Fisher, P.B.5
  • 35
    • 33746257314 scopus 로고    scopus 로고
    • Melanoma differentiation-associated gene-7 (mda-7)/interleukin (IL)-24 induces anticancer immunity in a syngeneic murine model
    • Miyahara R., Banerjee S., Kawano K., Efferson C., Tsuda N., Miyahara Y., Ioannides C.G., and Chada S. Melanoma differentiation-associated gene-7 (mda-7)/interleukin (IL)-24 induces anticancer immunity in a syngeneic murine model. Cancer Gene Ther. 13 (2006) 753-761
    • (2006) Cancer Gene Ther. , vol.13 , pp. 753-761
    • Miyahara, R.1    Banerjee, S.2    Kawano, K.3    Efferson, C.4    Tsuda, N.5    Miyahara, Y.6    Ioannides, C.G.7    Chada, S.8
  • 36
    • 33644508374 scopus 로고    scopus 로고
    • High mda-7 expression promotes malignant cell survival and p38 MAP kinase activation in chronic lymphocytic leukemia
    • Sainz-Perez A., Gary-Gouy H., Portier A., Davi F., Merle-Beral H., Galanaud P., and Dalloul A. High mda-7 expression promotes malignant cell survival and p38 MAP kinase activation in chronic lymphocytic leukemia. Leukemia 20 (2006) 498-504
    • (2006) Leukemia , vol.20 , pp. 498-504
    • Sainz-Perez, A.1    Gary-Gouy, H.2    Portier, A.3    Davi, F.4    Merle-Beral, H.5    Galanaud, P.6    Dalloul, A.7
  • 37
    • 0037162507 scopus 로고    scopus 로고
    • mda-7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK
    • Sarkar D., Su Z.-z., Lebedeva I.V., Sauane M., Gopalkrishnan R.V., Valerie K., Dent P., and Fisher P.B. mda-7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 10054-10059
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 10054-10059
    • Sarkar, D.1    Su, Z.-z.2    Lebedeva, I.V.3    Sauane, M.4    Gopalkrishnan, R.V.5    Valerie, K.6    Dent, P.7    Fisher, P.B.8
  • 38
    • 7244245840 scopus 로고    scopus 로고
    • mda-9/syntenin: recent insights into a novel cell signaling and metastasis-associated gene
    • Sarkar D., Boukerche H., Su Z.-z., and Fisher P.B. mda-9/syntenin: recent insights into a novel cell signaling and metastasis-associated gene. Pharmacol. Ther. 104 (2004) 101-115
    • (2004) Pharmacol. Ther. , vol.104 , pp. 101-115
    • Sarkar, D.1    Boukerche, H.2    Su, Z.-z.3    Fisher, P.B.4
  • 39
    • 25444519500 scopus 로고    scopus 로고
    • Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice
    • Sarkar D., Su Z.Z., Vozhilla N., Park E.S., Gupta P., and Fisher P.B. Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 14034-14039
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 14034-14039
    • Sarkar, D.1    Su, Z.Z.2    Vozhilla, N.3    Park, E.S.4    Gupta, P.5    Fisher, P.B.6
  • 40
    • 33746265063 scopus 로고    scopus 로고
    • Unique conditionally replication competent bipartite adenoviruses-cancer terminator viruses (CTV): efficacious reagents for cancer gene therapy
    • Sarkar D., Su Z.-z., and Fisher P.B. Unique conditionally replication competent bipartite adenoviruses-cancer terminator viruses (CTV): efficacious reagents for cancer gene therapy. Cell Cycle 5 (2006) 1531-1536
    • (2006) Cell Cycle , vol.5 , pp. 1531-1536
    • Sarkar, D.1    Su, Z.-z.2    Fisher, P.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.