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Volumn 11, Issue 5, 2010, Pages 434-443

Mechanisms of mdma (ecstasy)-induced oxidative stress, mitochondrial dysfunction, and organ damage

Author keywords

Functional redox proteomics; MDMA; Metabolism; Mitochondrial dysfunction; Organ damage; Oxidative nitrosative stress; Protein oxidation

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ALCOHOL; BIOTIN; CYSTEINE; MALEIMIDE; MITOCHONDRIAL PROTEIN;

EID: 77956563187     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920110791591436     Document Type: Article
Times cited : (57)

References (107)
  • 1
    • 0036324580 scopus 로고    scopus 로고
    • MDMA: A review of epidemiologic data
    • Landry, M. J. MDMA: a review of epidemiologic data. J. Psychoactive Drugs, 2002, 34 (2), 163-169.
    • (2002) J. Psychoactive Drugs , vol.34 , Issue.2 , pp. 163-169
    • Landry, M.J.1
  • 2
    • 33645730370 scopus 로고    scopus 로고
    • Ecstasy (MDMA, MDA, MDEA, MBDB) consumption, seizures, related offences, prices, dosage levels and deaths in the UK (1994-2003)
    • Schifano,F.; Corkery, J.; Deluca, P.; Oyefeso, A.; Ghodse, A. H. Ecstasy (MDMA, MDA, MDEA, MBDB) consumption, seizures, related offences, prices, dosage levels and deaths in the UK (1994-2003). J. Psychopharmacol., 2006, 20 (3), 456-463.
    • (2006) J. Psychopharmacol , vol.20 , Issue.3 , pp. 456-463
    • Schifano, F.1    Corkery, J.2    Deluca, P.3    Oyefeso, A.4    Ghodse, A.H.5
  • 3
    • 33845400967 scopus 로고    scopus 로고
    • Ecstasy and gateway drugs: Initiating the use of ecstasy and other drugs
    • Reid, L. W.; Elifson, K. W.; Sterk, C. E. Ecstasy and gateway drugs: initiating the use of ecstasy and other drugs. Ann. Epidemiol., 2007, 17 (1), 74-80.
    • (2007) Ann. Epidemiol , vol.17 , Issue.1 , pp. 74-80
    • Reid, L.W.1    Elifson, K.W.2    Sterk, C.E.3
  • 4
    • 0032576351 scopus 로고    scopus 로고
    • Fatal interaction between ritonavir and MDMA
    • Henry, J.A.; Hill, I.R. Fatal interaction between ritonavir and MDMA. Lancet, 1998, 352 (9142), 1751-1752.
    • (1998) Lancet , vol.352 , Issue.9142 , pp. 1751-1752
    • Henry, J.A.1    Hill, I.R.2
  • 5
    • 0033547191 scopus 로고    scopus 로고
    • Life-threatening interactions between HIV-1 protease inhibitors and the illicit drugs MDMA and gamma-hydroxybutyrate
    • Harrington, R. D.; Woodward, J. A.; Hooton, T. M.; Horn, J. R. Life-threatening interactions between HIV-1 protease inhibitors and the illicit drugs MDMA and gamma-hydroxybutyrate. Arch. Intern. Med., 1999, 159 (18), 2221-2224.
    • (1999) Arch. Intern. Med , vol.159 , Issue.18 , pp. 2221-2224
    • Harrington, R.D.1    Woodward, J.A.2    Hooton, T.M.3    Horn, J.R.4
  • 6
    • 33746911657 scopus 로고    scopus 로고
    • MDMA and alcohol effects, combined and alone, on objective and subjective measures of actual driving performance and psychomotor function
    • Kuypers, K. P.; Samyn, N.; Ramaekers, J. G. MDMA and alcohol effects, combined and alone, on objective and subjective measures of actual driving performance and psychomotor function. Psychopharmacology, 2006, 187 (4), 467-475.
    • (2006) Psychopharmacology , vol.187 , Issue.4 , pp. 467-475
    • Kuypers, K.P.1    Samyn, N.2    Ramaekers, J.G.3
  • 7
    • 0032881255 scopus 로고    scopus 로고
    • Adam (MDMA) and Eve (MDEA) misuse: An immunohistochemical study on three fatal cases
    • Fineschi, V.; Centini, F.; Mazzeo, E.; Turillazzi, E. Adam (MDMA) and Eve (MDEA) misuse: an immunohistochemical study on three fatal cases. Forensic Sci. Int., 1999, 104 (1), 65-74.
    • (1999) Forensic Sci. Int , vol.104 , Issue.1 , pp. 65-74
    • Fineschi, V.1    Centini, F.2    Mazzeo, E.3    Turillazzi, E.4
  • 8
    • 0345689650 scopus 로고    scopus 로고
    • Methylene 3, 4 dioxymethamphetamine-induced acute myocardial infarction
    • Lai, T. I.; Hwang, J. J.; Fang, C. C.; Chen, W. J. Methylene 3, 4 dioxymethamphetamine-induced acute myocardial infarction Ann. Emerg. Med., 2003, 42 (6), 759-762.
    • (2003) Ann. Emerg. Med , vol.42 , Issue.6 , pp. 759-762
    • Lai, T.I.1    Hwang, J.J.2    Fang, C.C.3    Chen, W.J.4
  • 10
    • 0030006302 scopus 로고    scopus 로고
    • Acute liver damage and ecstasy ingestion
    • Ellis, A. J.; Wendon, J. A.; Portmann, B.; Williams, R. Acute liver damage and ecstasy ingestion. Gut, 1996, 38 (3), 454-458.
    • (1996) Gut , vol.38 , Issue.3 , pp. 454-458
    • Ellis, A.J.1    Wendon, J.A.2    Portmann, B.3    Williams, R.4
  • 13
    • 0036390214 scopus 로고    scopus 로고
    • Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: An in vitro study using rat and human renal proximal tubular cells
    • Carvalho, M.; Hawksworth, G.; Milhazes, N.; Borges, F.; Monks, T. J.; Fernandes, E.; Carvalho, F.; Bastos, M. L. Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells. Arch. Toxicol., 2002, 76 (10), 581-588.
    • (2002) Arch. Toxicol , vol.76 , Issue.10 , pp. 581-588
    • Carvalho, M.1    Hawksworth, G.2    Milhazes, N.3    Borges, F.4    Monks, T.J.5    Fernandes, E.6    Carvalho, F.7    Bastos, M.L.8
  • 15
    • 58149335160 scopus 로고    scopus 로고
    • The agony of ecstasy: MDMA (3,4-methylenedioxymethamphetamine) and the kidney
    • Campbell, G. A.; Rosner, M. H. The agony of ecstasy: MDMA (3,4-methylenedioxymethamphetamine) and the kidney. Clin. J. Am. Soc. Nephrol., 2008, 3 (6), 1852-1860.
    • (2008) Clin. J. Am. Soc. Nephrol , vol.3 , Issue.6 , pp. 1852-1860
    • Campbell, G.A.1    Rosner, M.H.2
  • 16
    • 0032968382 scopus 로고    scopus 로고
    • Cardiovascular and neuroendocrine effects and pharmacokinetics of 3, 4-methylenedioxy methamphetamine in humans
    • Mas, M.; Farré, M.; de la Torre, R.; Roset, P. N.; Ortuño, J.; Segura, J.; Camí, J. Cardiovascular and neuroendocrine effects and pharmacokinetics of 3, 4-methylenedioxy methamphetamine in humans. J. Pharmacol. Exp. Ther., 1999, 290 (1), 136-145.
    • (1999) J. Pharmacol. Exp. Ther , vol.290 , Issue.1 , pp. 136-145
    • Mas, M.1    Farré, M.2    de la Torre, R.3    Roset, P.N.4    Ortuño, J.5    Segura, J.6    Camí, J.7
  • 18
    • 0031932040 scopus 로고    scopus 로고
    • Acute 3,4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat
    • Connor, T. J.; McNamara, M. G.; Finn, D.; Currid, A.; O'Malley, M.; Redmond, A. M.; Kelly, J. P.; Leonard, B. E. Acute 3,4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat. Immunopharmacology, 1998, 38 (3), 253-260.
    • (1998) Immunopharmacology , vol.38 , Issue.3 , pp. 253-260
    • Connor, T.J.1    McNamara, M.G.2    Finn, D.3    Currid, A.4    O'Malley, M.5    Redmond, A.M.6    Kelly, J.P.7    Leonard, B.E.8
  • 19
    • 33646920890 scopus 로고    scopus 로고
    • Causes and consequences of methamphetamine and MDMA toxicity
    • Quinton, M. S.; Yamamoto, B. K. Causes and consequences of methamphetamine and MDMA toxicity. AAPS J., 2006, 8 (2): E337-E347.
    • (2006) AAPS J , vol.8 , Issue.2
    • Quinton, M.S.1    Yamamoto, B.K.2
  • 20
    • 69449095628 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of ecstasyinduced neurotoxicity: An overview
    • Capela, J. P.; Carmo, H.; Remião, F.; Bastos, M. L.; Meisel, A.; Carvalho, F. Molecular and cellular mechanisms of ecstasyinduced neurotoxicity: an overview. Mol. Neurobiol., 2009, 39 (3), 210-271.
    • (2009) Mol. Neurobiol , vol.39 , Issue.3 , pp. 210-271
    • Capela, J.P.1    Carmo, H.2    Remião, F.3    Bastos, M.L.4    Meisel, A.5    Carvalho, F.6
  • 21
    • 0034933347 scopus 로고    scopus 로고
    • Serotonergic neurotoxicity of 3,4-(+/-)-methylenedioxyamphetamine and 3,4-(+/-)-methylendioxymethamphetamine (ecstasy) is potentiated by inhibition of gamma-glutamyl transpeptidase
    • Bai, F.; Jones, D. C.; Lau, S. S.; Monks, T. J. Serotonergic neurotoxicity of 3,4-(+/-)-methylenedioxyamphetamine and 3,4-(+/-)-methylendioxymethamphetamine (ecstasy) is potentiated by inhibition of gamma-glutamyl transpeptidase. Chem. Res. Toxicol., 2001, 14 (7), 863-870.
    • (2001) Chem. Res. Toxicol , vol.14 , Issue.7 , pp. 863-870
    • Bai, F.1    Jones, D.C.2    Lau, S.S.3    Monks, T.J.4
  • 23
    • 20544440847 scopus 로고    scopus 로고
    • Elevation of ambient room temperature has differential effects on MDMA-induced 5-HT and dopamine release in striatum and nucleus accumbens of rats
    • O'Shea, E.; Escobedo, I.; Orio, L.; Sanchez, V.; Navarro, M.; Green, A. R.; Colado, M. I. Elevation of ambient room temperature has differential effects on MDMA-induced 5-HT and dopamine release in striatum and nucleus accumbens of rats. Neuropsychopharmacology, 2005, 30 (7), 1312-1323.
    • (2005) Neuropsychopharmacology , vol.30 , Issue.7 , pp. 1312-1323
    • O'Shea, E.1    Escobedo, I.2    Orio, L.3    Sanchez, V.4    Navarro, M.5    Green, A.R.6    Colado, M.I.7
  • 24
    • 4644282282 scopus 로고    scopus 로고
    • A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response
    • Green, A. R.; O'Shea, E.; Colado, M. I. A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response. Eur. J. Pharmacol., 2004, 500 (1-3), 3-13.
    • (2004) Eur. J. Pharmacol , vol.500 , Issue.1-3 , pp. 3-13
    • Green, A.R.1    O'Shea, E.2    Colado, M.I.3
  • 25
    • 0026662216 scopus 로고
    • Biochemical and toxicological properties of the oxidation products of catecholamines
    • Bindoli, A.; Rigobello, M. P., Deeble, D. J. Biochemical and toxicological properties of the oxidation products of catecholamines. Free Radic. Biol. Med., 1992, 13 (4), 391-405.
    • (1992) Free Radic. Biol. Med , vol.13 , Issue.4 , pp. 391-405
    • Bindoli, A.1    Rigobello, M.P.2    Deeble, D.J.3
  • 26
    • 33750209029 scopus 로고    scopus 로고
    • Synthesis and cytotoxic profile of 3,4-methylenedioxymethamphetamine (ecstasy) and its metabolites on undifferentiated PC12 cells: A putative structure-toxicity relationship
    • Milhazes, N.; Cunha-Oliveira, T.; Martins, P.; Garrido, J.; Oliveira, C,; Rego, A. C.; Borges, F. Synthesis and cytotoxic profile of 3,4-methylenedioxymethamphetamine (ecstasy) and its metabolites on undifferentiated PC12 cells: A putative structure-toxicity relationship. Chem. Res. Toxicol., 2006, 19 (10), 1294-1304.
    • (2006) Chem. Res. Toxicol , vol.19 , Issue.10 , pp. 1294-1304
    • Milhazes, N.1    Cunha-Oliveira, T.2    Martins, P.3    Garrido, J.4    Oliveira, C.5    Rego, A.C.6    Borges, F.7
  • 27
    • 2942714874 scopus 로고    scopus 로고
    • The toxicity of N-methyl-alphamethyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine
    • Carvalho, M.; Remião, F.; Milhazes, N.; Borges, F.; Fernandes, E.; Carvalho, F.; Bastos, M. L. The toxicity of N-methyl-alphamethyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine. Toxicology, 2004, 200 (2-3), 193-203.
    • (2004) Toxicology , vol.200 , Issue.2-3 , pp. 193-203
    • Carvalho, M.1    Remião, F.2    Milhazes, N.3    Borges, F.4    Fernandes, E.5    Carvalho, F.6    Bastos, M.L.7
  • 29
    • 1542330614 scopus 로고    scopus 로고
    • Role of reactive oxygen species, glutathione and NF-kappaB in apoptosis induced by 3,4-methylenedioxy methamphetamine (Ecstasy) on hepatic stellate cells
    • Montiel-Duarte, C.; Ansorena, E.; Lopez-Zabalza, M. J.; Cenarruzabeitia, E.; Iraburu, M. J.; Cenarruzabeitia, E.; Iraburu, M. J. Role of reactive oxygen species, glutathione and NF-kappaB in apoptosis induced by 3,4-methylenedioxy methamphetamine (Ecstasy) on hepatic stellate cells. Biochem. Pharmacol., 2004, 67 (6), 1025-1033.
    • (2004) Biochem. Pharmacol , vol.67 , Issue.6 , pp. 1025-1033
    • Montiel-Duarte, C.1    Ansorena, E.2    Lopez-Zabalza, M.J.3    Cenarruzabeitia, E.4    Iraburu, M.J.5    Cenarruzabeitia, E.6    Iraburu, M.J.7
  • 30
    • 0030951385 scopus 로고    scopus 로고
    • 2,5-Bis-(glutathion-S-yl)-alpha-methyldopamine, a putative metabolite of (+/-)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations
    • Miller, R. T.; Lau, S. S.; Monks, T. J. 2,5-Bis-(glutathion-S-yl)-alpha-methyldopamine, a putative metabolite of (+/-)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations. Eur. J. Pharmacol., 1997, 323 (2-3), 173-180.
    • (1997) Eur. J. Pharmacol , vol.323 , Issue.2-3 , pp. 173-180
    • Miller, R.T.1    Lau S., S.2    Monks, T.J.3
  • 32
    • 0026598872 scopus 로고
    • Lack of serotonin neurotoxicity after intraraphe microinjection of (+)-3,4-methylenedioxymethamphetamine (MDMA)
    • Paris, J. M.; Cunningham, K. A. Lack of serotonin neurotoxicity after intraraphe microinjection of (+)-3,4-methylenedioxymethamphetamine (MDMA). Brain Res. Bull., 1992, 28 (1), 115-119.
    • (1992) Brain Res. Bull , vol.28 , Issue.1 , pp. 115-119
    • Paris, J.M.1    Cunningham, K.A.2
  • 34
    • 0032903612 scopus 로고    scopus 로고
    • Overexpression of human copper/zinc superoxide dismutase in transgenic mice attenuates oxidative stress caused by methylenedioxymethamphetamine (Ecstasy)
    • Jayanthi, S.; Ladenheim, B.; Andrews, A. M.; Cadet, J. L. Overexpression of human copper/zinc superoxide dismutase in transgenic mice attenuates oxidative stress caused by methylenedioxymethamphetamine (Ecstasy). Neuroscience, 1999, 91 (4), 1379-1387.
    • (1999) Neuroscience , vol.91 , Issue.4 , pp. 1379-1387
    • Jayanthi, S.1    Ladenheim, B.2    Andrews A., M.3    Cadet, J.L.4
  • 36
    • 58149463913 scopus 로고    scopus 로고
    • Acetyl-Lcarnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain
    • Alves, E.; Binienda, Z.; Carvalho, F.; Alves, C. J.; Fernandes, E.; de Lourdes Bastos, M.; Tavares, M. A.; Summavielle, T. Acetyl-Lcarnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain. Neuroscience, 2009, 158 (2), 514-523.
    • (2009) Neuroscience , vol.158 , Issue.2 , pp. 514-523
    • Alves, E.1    Binienda, Z.2    Carvalho, F.3    Alves, C.J.4    Fernandes, E.5    de Lourdes Bastos, M.6    Tavares, M.A.7    Summavielle, T.8
  • 37
    • 13244259290 scopus 로고    scopus 로고
    • Evidence for the involvement of nitric oxide in 3,4-methylenedioxymethamphetamine-induced serotonin depletion in the rat brain
    • Darvesh, A. S.; Yamamoto, B. K.; Gudelsky, G. A. Evidence for the involvement of nitric oxide in 3,4-methylenedioxymethamphetamine-induced serotonin depletion in the rat brain. J. Pharmacol. Exp. Ther., 2005, 312 (2), 694-701.
    • (2005) J. Pharmacol. Exp. Ther , vol.312 , Issue.2 , pp. 694-701
    • Darvesh, A.S.1    Yamamoto, B.K.2    Gudelsky, G.A.3
  • 38
    • 0032496695 scopus 로고    scopus 로고
    • Role of brain nitric oxide in (+/-)3,4-methylenedioxy methamphetamine (MDMA)-induced neurotoxicity in rats
    • Zheng, Y.; Laverty, R. Role of brain nitric oxide in (+/-)3,4-methylenedioxy methamphetamine (MDMA)-induced neurotoxicity in rats. Brain Res., 1998, 795 (1-2), 257-263.
    • (1998) Brain Res , vol.795 , Issue.1-2 , pp. 257-263
    • Zheng, Y.1    Laverty, R.2
  • 39
    • 33746810059 scopus 로고    scopus 로고
    • Amphetamine neurotoxicity: Cause and consequence of oxidative stress
    • Yamamoto, B. K.; Bankson, M. G. Amphetamine neurotoxicity: Cause and consequence of oxidative stress. Crit. Rev. Neurol., 2005, 17 (2), 87-117.
    • (2005) Crit. Rev. Neurol , vol.17 , Issue.2 , pp. 87-117
    • Yamamoto, B.K.1    Bankson, M.G.2
  • 40
    • 55849102476 scopus 로고    scopus 로고
    • The role of oxidative stress, metabolic compromise, and inflammation in neuronal injury produced by amphetamine-related drugs of abuse
    • Yamamoto, B. K.; Raudensky, J. The role of oxidative stress, metabolic compromise, and inflammation in neuronal injury produced by amphetamine-related drugs of abuse. J. Neuroimmune Pharmacol., 2008, 3 (4), 203-217.
    • (2008) J. Neuroimmune Pharmacol , vol.3 , Issue.4 , pp. 203-217
    • Yamamoto, B.K.1    Raudensky, J.2
  • 41
    • 22544477523 scopus 로고    scopus 로고
    • Drug-associated mitochondrial toxicity and its detection
    • Amacher, D.E. Drug-associated mitochondrial toxicity and its detection. Curr. Med. Chem., 2005, 12 (16), 1829-1839.
    • (2005) Curr. Med. Chem , vol.12 , Issue.16 , pp. 1829-1839
    • Amacher, D.E.1
  • 42
    • 32844458032 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in NASH: Causes, consequences and possible means to prevent it
    • Begriche, K.; Igoudjil, A.; Pessayre, D.; Fromenty, B. Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it. Mitochondrion, 2006, 6 (1), 1-28.
    • (2006) Mitochondrion , vol.6 , Issue.1 , pp. 1-28
    • Begriche, K.1    Igoudjil, A.2    Pessayre, D.3    Fromenty, B.4
  • 43
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin, M. T.; Beal. M. F. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature, 2006, 443 (7113), 787-795.
    • (2006) Nature , vol.443 , Issue.7113 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 44
    • 53549125568 scopus 로고    scopus 로고
    • Mechanism of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated mitochondrial dysfunction in rat liver
    • Moon, K. H.; Upreti, V. V.; Yu, L. R.; Lee, I. J.; Ye, X.; Eddington, N. D.; Veenstra, T. D.; Song, B. J. Mechanism of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated mitochondrial dysfunction in rat liver. Proteomics, 2008, 8 (18), 3906-3918.
    • (2008) Proteomics , vol.8 , Issue.18 , pp. 3906-3918
    • Moon, K.H.1    Upreti, V.V.2    Yu, L.R.3    Lee, I.J.4    Ye, X.5    Eddington, N.D.6    Veenstra, T.D.7    Song, B.J.8
  • 46
    • 33846863589 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite in health and disease
    • Pacher, P.; Beckman, J. S.; Liaudet, L. Nitric oxide and peroxynitrite in health and disease. Physiol. Rev., 2007, 87(1), 315-424.
    • (2007) Physiol. Rev , vol.87 , Issue.1 , pp. 315-424
    • Pacher, P.1    Beckman, J.S.2    Liaudet, L.3
  • 47
    • 0025730414 scopus 로고
    • Peroxynitrite oxidation of sulfhydryls: The cytotoxic potential of superoxide and nitric oxide
    • Radi, R.; Beckman, J. S.; Bush, K. M.; Freeman, B. A. Peroxynitrite oxidation of sulfhydryls: The cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem., 1991, 266 (7), 4244-4250.
    • (1991) J. Biol. Chem , vol.266 , Issue.7 , pp. 4244-4250
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 48
    • 0345222531 scopus 로고    scopus 로고
    • Mitochondrial function is differentially affected upon oxidative stress
    • Cardoso, S. M.; Pereira, C.; Oliveira, R. Mitochondrial function is differentially affected upon oxidative stress. Free Radic. Biol. Med., 1999, 26 (1-2), 3-13.
    • (1999) Free Radic. Biol. Med , vol.26 , Issue.1-2 , pp. 3-13
    • Cardoso, S.M.1    Pereira, C.2    Oliveira, R.3
  • 49
    • 0141510019 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial complex I due to peroxynitrite. Identification of reactive tyrosines by mass spectrometry
    • Murray, J.; Taylor, S. W.; Zhang, B.; Ghosh, S. S.; Capaldi, R. A. Oxidative damage to mitochondrial complex I due to peroxynitrite. Identification of reactive tyrosines by mass spectrometry. J. Biol. Chem., 2003, 278 (39), 37223-37230.
    • (2003) J. Biol. Chem , vol.278 , Issue.39 , pp. 37223-37230
    • Murray, J.1    Taylor, S.W.2    Zhang, B.3    Ghosh, S.S.4    Capaldi, R.A.5
  • 50
    • 0029078456 scopus 로고
    • The monoamine oxidase-B inhibitor L-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits
    • Sprague, J. E.; Nichols, D. E. The monoamine oxidase-B inhibitor L-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits. J. Pharmacol. Exp. Ther., 1995, 273 (2), 667-673.
    • (1995) J. Pharmacol. Exp. Ther , vol.273 , Issue.2 , pp. 667-673
    • Sprague, J.E.1    Nichols, D.E.2
  • 51
    • 8744304760 scopus 로고    scopus 로고
    • Identification of oxidized mitochondrial proteins in alcohol-exposed human hepatoma cells and mouse liver
    • Suh, S. K.; Hood, B. L.; Kim, B. J.; Conrads, T. P.; Veenstra, T. D.; Song, B. J. Identification of oxidized mitochondrial proteins in alcohol-exposed human hepatoma cells and mouse liver. Proteomics, 2004, 4 (11), 3401-3412.
    • (2004) Proteomics , vol.4 , Issue.11 , pp. 3401-3412
    • Suh, S.K.1    Hood, B.L.2    Kim, B.J.3    Conrads, T.P.4    Veenstra, T.D.5    Song, B.J.6
  • 52
    • 33644500142 scopus 로고    scopus 로고
    • Increased oxidation and degradation of cytosolic proteins in alcohol-exposed mouse liver and hepatoma cells
    • Kim, B. J.; Hood, B. L.; Aragon, R. A.; Hardwick, J. P.; Conrads, T. P.; Veenstra, T. D.; Song, B. J. Increased oxidation and degradation of cytosolic proteins in alcohol-exposed mouse liver and hepatoma cells. Proteomics, 2006, 6 (4), 1250-1260.
    • (2006) Proteomics , vol.6 , Issue.4 , pp. 1250-1260
    • Kim, B.J.1    Hood, B.L.2    Aragon, R.A.3    Hardwick, J.P.4    Conrads, T.P.5    Veenstra, T.D.6    Song, B.J.7
  • 53
    • 33751003258 scopus 로고    scopus 로고
    • Inactivation of oxidized and S-nitrosylated mitochondrial proteins in alcoholic fatty liver of rats
    • Moon, K. H.; Hood, B. L.; Kim, B. J.; Hardwick, J. P.; Conrads, T. P.; Veenstra, T. D.; Song, B. J. Inactivation of oxidized and S-nitrosylated mitochondrial proteins in alcoholic fatty liver of rats. Hepatology, 2006, 44 (5), 1218-1230.
    • (2006) Hepatology , vol.44 , Issue.5 , pp. 1218-1230
    • Moon, K.H.1    Hood, B.L.2    Kim, B.J.3    Hardwick, J.P.4    Conrads, T.P.5    Veenstra, T.D.6    Song, B.J.7
  • 55
    • 0030841350 scopus 로고    scopus 로고
    • Protein oxidation in aging, disease, and oxidative stress
    • Berlett, B. S.; Stadtman, E. R. Protein oxidation in aging, disease, and oxidative stress. J. Biol. Chem., 1997, 272 (33), 20313-20316.
    • (1997) J. Biol. Chem , vol.272 , Issue.33 , pp. 20313-20316
    • Berlett, B.S.1    Stadtman, E.R.2
  • 56
    • 27544510276 scopus 로고    scopus 로고
    • Inhibition of mitochondrial aldehyde dehydrogenase by nitric oxide-mediated S-nitrosylation
    • Moon, K. H.; Kim, B. J.; Song, B. J. Inhibition of mitochondrial aldehyde dehydrogenase by nitric oxide-mediated S-nitrosylation. FEBS Lett., 2005, 579 (27), 6115-6120.
    • (2005) FEBS Lett , vol.579 , Issue.27 , pp. 6115-6120
    • Moon, K.H.1    Kim, B.J.2    Song, B.J.3
  • 57
    • 34547666779 scopus 로고    scopus 로고
    • Inactivation of cytosolic aldehyde dehydrogenase via S-nitrosylation in ethanolexposed rat liver
    • Moon, K. H.; Abdelmegeed, M. A.; Song, B. J. Inactivation of cytosolic aldehyde dehydrogenase via S-nitrosylation in ethanolexposed rat liver. FEBS Lett., 2007, 581 (21), 3967-3972.
    • (2007) FEBS Lett , vol.581 , Issue.21 , pp. 3967-3972
    • Moon, K.H.1    Abdelmegeed, M.A.2    Song, B.J.3
  • 58
    • 0030002384 scopus 로고    scopus 로고
    • Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation
    • Gow, A. J.; Duran, D.; Malcolm, S.; Ischiropoulos, H. Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation. FEBS Lett., 1996, 385 (1-2), 63-66.
    • (1996) FEBS Lett , vol.385 , Issue.1-2 , pp. 63-66
    • Gow, A.J.1    Duran, D.2    Malcolm, S.3    Ischiropoulos, H.4
  • 59
    • 34447631179 scopus 로고    scopus 로고
    • Hyperammonemia causes protein oxidation and enhanced proteasomal activity in response to mitochondria-mediated oxidative stress in rat primary astrocytes
    • Widmer, R.; Kaiser, B.; Engels, M.; Jung, T.; Grune, T. Hyperammonemia causes protein oxidation and enhanced proteasomal activity in response to mitochondria-mediated oxidative stress in rat primary astrocytes. Arch. Biochem. Biophys., 2007, 464 (1), 1-11.
    • (2007) Arch. Biochem. Biophys , vol.464 , Issue.1 , pp. 1-11
    • Widmer, R.1    Kaiser, B.2    Engels, M.3    Jung, T.4    Grune, T.5
  • 60
    • 0034255470 scopus 로고    scopus 로고
    • Identification of proteins containing cysteine residues that are sensitive to oxidation by hydrogen peroxide at neutral pH
    • Kim, J. R.; Yoon, H. W.; Kwon, K. S.; Lee, S. R.; Rhee, S. G. Identification of proteins containing cysteine residues that are sensitive to oxidation by hydrogen peroxide at neutral pH. Anal. Biochem., 2000, 283 (2), 214-221.
    • (2000) Anal. Biochem , vol.283 , Issue.2 , pp. 214-221
    • Kim, J.R.1    Yoon, H.W.2    Kwon, K.S.3    Lee, S.R.4    Rhee, S.G.5
  • 62
    • 2642576571 scopus 로고    scopus 로고
    • Isotope-coded affinity tag approach to identify and quantify oxidant-sensitive protein thiols
    • Sethuraman, M.; McComb, M. E.; Heibeck, T.; Costello, C. E.; Cohen, R. A. Isotope-coded affinity tag approach to identify and quantify oxidant-sensitive protein thiols. Mol. Cell Proteomics, 2004, 3 (3), 273-278.
    • (2004) Mol. Cell Proteomics , vol.3 , Issue.3 , pp. 273-278
    • Sethuraman, M.1    McComb, M.E.2    Heibeck, T.3    Costello, C.E.4    Cohen, R.A.5
  • 63
    • 0343376097 scopus 로고    scopus 로고
    • Difference gel electrophoresis: A single gel method for detecting changes in protein extracts
    • Unlü, M.; Morgan, M. E.; Minden, J. S. Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Electrophoresis, 1997, 18 (11), 2071-2077.
    • (1997) Electrophoresis , vol.18 , Issue.11 , pp. 2071-2077
    • Unlü, M.1    Morgan, M.E.2    Minden, J.S.3
  • 65
    • 0037049991 scopus 로고    scopus 로고
    • Proteomic alterations of the variants of human aldehyde dehydrogenase isozymes correlate with hepatocellular carcinoma
    • Park, K. S.; Cho, S. Y.; Kim, H.; Paik, Y. K. Proteomic alterations of the variants of human aldehyde dehydrogenase isozymes correlate with hepatocellular carcinoma. Int. J. Cancer, 2002, 97 (2), 261-265.
    • (2002) Int. J. Cancer , vol.97 , Issue.2 , pp. 261-265
    • Park, K.S.1    Cho, S.Y.2    Kim, H.3    Paik, Y.K.4
  • 66
    • 12244254485 scopus 로고    scopus 로고
    • Proteome analysis of human liver tumor tissue by two-dimensional gel electrophoresis and matrix assisted laser desorption/ionization-mass spectrometry for identification of disease-related proteins
    • Kim, J.; Kim, S. H.; Lee, S. U.; Ha, G. H.; Kang, D. G.; Ha, N. Y.; Ahn, J. S.; Cho, H. Y.; Kang, S. J.; Lee, Y. J.; Hong, S. C.; Ha, W. S.; Bae, J. M.; Lee, C. W.; Kim, J. W. Proteome analysis of human liver tumor tissue by two-dimensional gel electrophoresis and matrix assisted laser desorption/ionization-mass spectrometry for identification of disease-related proteins. Electrophoresis, 2002, 23 (24), 4142-4156.
    • (2002) Electrophoresis , vol.23 , Issue.24 , pp. 4142-4156
    • Kim, J.1    Kim, S.H.2    Lee, S.U.3    Ha, G.H.4    Kang, D.G.5    Ha, N.Y.6    Ahn, J.S.7    Cho, H.Y.8    Kang, S.J.9    Lee, Y.J.10    Hong, S.C.11    Ha, W.S.12    Bae, J.M.13    Lee, C.W.14    Kim, J.W.15
  • 67
    • 2642579275 scopus 로고    scopus 로고
    • Expression and purification of His-tagged rat mitochondrial 3-ketoacyl-CoA thiolase wild-type and His352 mutant proteins
    • Zeng, J.; Li, D. Expression and purification of His-tagged rat mitochondrial 3-ketoacyl-CoA thiolase wild-type and His352 mutant proteins. Protein Expr. Purif., 2004, 35 (2), 320-326.
    • (2004) Protein Expr. Purif , vol.35 , Issue.2 , pp. 320-326
    • Zeng, J.1    Li, D.2
  • 68
    • 0023340210 scopus 로고
    • cDNA-derived amino acid sequence of rat mitochondrial 3-oxoacyl-CoA thiolase with no transient presequence: Structural relationship with peroxisomal isozyme
    • Arakawa, H.; Takiguchi, M.; Amaya, Y.; Nagata, S.; Hayashi, H.; Mori, M. cDNA-derived amino acid sequence of rat mitochondrial 3-oxoacyl-CoA thiolase with no transient presequence: structural relationship with peroxisomal isozyme. EMBO J., 1987, 6 (5), 1361-1366.
    • (1987) EMBO J , vol.6 , Issue.5 , pp. 1361-1366
    • Arakawa, H.1    Takiguchi, M.2    Amaya, Y.3    Nagata, S.4    Hayashi, H.5    Mori, M.6
  • 69
    • 68349131724 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor-alpha in fasting-mediated oxidative stress
    • Abdelmegeed, M. A.; Moon, K. H.; Hardwick, J. P.; Gonzalez, F. J.; Song, B. J. Role of peroxisome proliferator-activated receptor-alpha in fasting-mediated oxidative stress. Free Radic. Biol. Med., 2009, 47 (6), 767-778.
    • (2009) Free Radic. Biol. Med , vol.47 , Issue.6 , pp. 767-778
    • Abdelmegeed, M.A.1    Moon, K.H.2    Hardwick, J.P.3    Gonzalez, F.J.4    Song, B.J.5
  • 70
    • 1642576090 scopus 로고    scopus 로고
    • Cytosolic peroxiredoxin attenuates the activation of JNK and p38 but potentiates that of ERK in Hela cells stimulated with tumor necrosis factor-alpha
    • Kang, S. W.; Chang, T. S.; Lee, T. H.; Kim, E. S.; Yu, D. Y.; Rhee, S. G. Cytosolic peroxiredoxin attenuates the activation of JNK and p38 but potentiates that of ERK in Hela cells stimulated with tumor necrosis factor-alpha. J. Biol. Chem., 2004, 279 (4), 2535-2543.
    • (2004) J. Biol. Chem , vol.279 , Issue.4 , pp. 2535-2543
    • Kang, S.W.1    Chang, T.S.2    Lee, T.H.3    Kim, E.S.4    Yu, D.Y.5    Rhee, S.G.6
  • 71
    • 44349148784 scopus 로고    scopus 로고
    • Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson disease
    • Lee, Y. M.; Park, S. H.; Shin, D. I.; Hwang, J. Y.; Park, B., Park, Y. J.; Lee, T. H.; Chae, H. Z.; Jin, B. K.; Oh, T. H.; Oh, Y. J. Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson disease. J. Biol. Chem., 2008, 283 (15), 9986-9998.
    • (2008) J. Biol. Chem , vol.283 , Issue.15 , pp. 9986-9998
    • Lee, Y.M.1    Park, S.H.2    Shin, D.I.3    Hwang, J.Y.4    Park, B.5    Park, Y.J.6    Lee, T.H.7    Chae, H.Z.8    Jin, B.K.9    Oh, T.H.10    Oh, Y.J.11
  • 73
    • 33746379603 scopus 로고    scopus 로고
    • JNK-and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells
    • Kim, B. J.; Ryu, S. W.; Song, B. J. JNK-and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells. J. Biol. Chem., 2006, 281 (30), 21256-21265.
    • (2006) J. Biol. Chem , vol.281 , Issue.30 , pp. 21256-21265
    • Kim, B.J.1    Ryu, S.W.2    Song, B.J.3
  • 75
    • 46149111662 scopus 로고    scopus 로고
    • Prevention of alcoholic fatty liver and mitochondrial dysfunction in the rat by long-chain polyunsaturated fatty acids
    • Song, B. J.; Moon, K. H.; Olsson, N. U.; Salem, N. Jr. Prevention of alcoholic fatty liver and mitochondrial dysfunction in the rat by long-chain polyunsaturated fatty acids. J. Hepatol., 2008, 49 (2), 262-273.
    • (2008) J. Hepatol , vol.49 , Issue.2 , pp. 262-273
    • Song, B.J.1    Moon, K.H.2    Olsson, N.U.3    Salem Jr., N.4
  • 76
    • 0033569921 scopus 로고    scopus 로고
    • Peroxynitrite inactivation of tryptophan hydroxylase via sulfhydryl oxidation: Coincident nitration of enzyme tyrosyl residues has minimal impact on catalytic activity
    • Kuhn, D. M.; Geddes, T. J. Peroxynitrite inactivation of tryptophan hydroxylase via sulfhydryl oxidation: Coincident nitration of enzyme tyrosyl residues has minimal impact on catalytic activity. J. Biol. Chem., 1999, 274 (42), 29726-29732.
    • (1999) J. Biol. Chem , vol.274 , Issue.42 , pp. 29726-29732
    • Kuhn, D.M.1    Geddes, T.J.2
  • 77
    • 0033499889 scopus 로고    scopus 로고
    • Peroxynitrite inactivation of tyrosine hydroxylase: Mediation by sulfhydryl oxidation, not tyrosine nitration
    • Kuhn, D. M.; Aretha, C. W.; Geddes, T. J. Peroxynitrite inactivation of tyrosine hydroxylase: mediation by sulfhydryl oxidation, not tyrosine nitration. J. Neurosci., 1999, 19 (23), 10289-10294.
    • (1999) J. Neurosci , vol.19 , Issue.23 , pp. 10289-10294
    • Kuhn, D.M.1    Aretha, C.W.2    Geddes, T.J.3
  • 78
    • 0032560486 scopus 로고    scopus 로고
    • Inactivation of tyrosine hydrozylase by niration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
    • Ara, J.; Przedborski, S.; Naini, A. B.; Jackson-Lewis, V.; Trifiletti, R. R.; Horwitz, J.; Ischiropoulos, H. Inactivation of tyrosine hydrozylase by niration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Proc. Natl. Acad. Sci. USA, 1998, 95 (13), 7659-7663.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.13 , pp. 7659-7663
    • Ara, J.1    Przedborski, S.2    Naini, A.B.3    Jackson-Lewis, V.4    Trifiletti, R.R.5    Horwitz, J.6    Ischiropoulos, H.7
  • 79
    • 73449119542 scopus 로고    scopus 로고
    • Inhibition of hepatic mitochondrial aldehyde dehydrogenase by carbon tetrachloride through JNK-mediated phosphorylation
    • Moon, K. H.; Lee, Y. M.; Song, B. J. Inhibition of hepatic mitochondrial aldehyde dehydrogenase by carbon tetrachloride through JNK-mediated phosphorylation. Free Radic. Biol. Med., 2010, 48, 391-398.
    • (2010) Free Radic. Biol. Med , vol.48 , pp. 391-398
    • Moon, K.H.1    Lee, Y.M.2    Song, B.J.3
  • 80
    • 0034813505 scopus 로고    scopus 로고
    • A putative metabolite of serotonin, trypamine-4,5-dione, is an irreversible inhibitor of tryptophan hydroxylase: Possible relevance to the serotonergic neurotoxicity of methamphetamine
    • Wrona, M. Z.; Dryhurst, G. A putative metabolite of serotonin, trypamine-4,5-dione, is an irreversible inhibitor of tryptophan hydroxylase: Possible relevance to the serotonergic neurotoxicity of methamphetamine. Chem. Res. Toxicol., 2001, 14 (9): 1184-1192.
    • (2001) Chem. Res. Toxicol , vol.14 , Issue.9 , pp. 1184-1192
    • Wrona, M.Z.1    Dryhurst, G.2
  • 81
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer, H.; Schaur, R. J.; Zollner, H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med., 1991, 11 (1), 81-128.
    • (1991) Free Radic. Biol. Med , vol.11 , Issue.1 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 82
    • 57249095767 scopus 로고    scopus 로고
    • Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions
    • Catalá, A. Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions. Chem. Phys. Lipids, 2009, 157 (1), 1-11.
    • (2009) Chem. Phys. Lipids , vol.157 , Issue.1 , pp. 1-11
    • Catalá, A.1
  • 83
    • 0037402885 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (MDMA) abuse may cause oxidative stress and potential free radical damage
    • Zhou, J. F.; Chen, P.; Zhou, Y. H.; Zhang, L.; Chen, H. H. 3,4-Methylenedioxymethamphetamine (MDMA) abuse may cause oxidative stress and potential free radical damage. Free Radic. Res., 2003, 37 (5), 491-497.
    • (2003) Free Radic. Res , vol.37 , Issue.5 , pp. 491-497
    • Zhou, J.F.1    Chen, P.2    Zhou, Y.H.3    Zhang, L.4    Chen, H.H.5
  • 84
    • 0031777186 scopus 로고    scopus 로고
    • The pharmacology and toxicology of polyphenolic-glutathione conjugates
    • Monks, T. J.; Lau, S. S. The pharmacology and toxicology of polyphenolic-glutathione conjugates. Annu. Rev. Pharmacol. Toxicol., 1998, 38, 229-255.
    • (1998) Annu. Rev. Pharmacol. Toxicol , vol.38 , pp. 229-255
    • Monks, T.J.1    Lau, S.S.2
  • 85
    • 0142151375 scopus 로고    scopus 로고
    • Oxidation of methionine residues of proteins: Biological consequences
    • Stadtman, E. R.; Moskovitz, J.; Levine, R. L. Oxidation of methionine residues of proteins: biological consequences. Antioxid. Redox Signal., 2003, 5 (5), 577-582.
    • (2003) Antioxid. Redox Signal , vol.5 , Issue.5 , pp. 577-582
    • Stadtman, E.R.1    Moskovitz, J.2    Levine, R.L.3
  • 86
    • 0035012664 scopus 로고    scopus 로고
    • Pathogenesis and treatment of renal dysfunction in rhabdomyolysis
    • Holt, S. G.; Moore, K. P. Pathogenesis and treatment of renal dysfunction in rhabdomyolysis. Intensive Care Med., 2001, 27 (5), 803-811.
    • (2001) Intensive Care Med , vol.27 , Issue.5 , pp. 803-811
    • Holt, S.G.1    Moore, K.P.2
  • 87
    • 0032951913 scopus 로고    scopus 로고
    • Ecstasy use in Australia: Patterns of use and associated harm
    • Topp, L.; Hando, J.; Dillon, P.; Roche, A.; Solowij, N. Ecstasy use in Australia: patterns of use and associated harm. Drug Alcohol Depend, 1999, 55 (1-2), 105-115.
    • (1999) Drug Alcohol Depend , vol.55 , Issue.1-2 , pp. 105-115
    • Topp, L.1    Hando, J.2    Dillon, P.3    Roche, A.4    Solowij, N.5
  • 88
    • 0035452496 scopus 로고    scopus 로고
    • Drugs and the dance music scene: A survey of current drug use patterns among a sample of dance music enthusiasts in the UK
    • Winstock, A. R.; Griffiths, P.; Stewart, D. Drugs and the dance music scene: a survey of current drug use patterns among a sample of dance music enthusiasts in the UK. Drug Alcohol Depend, 2001, 64 (1), 9-17.
    • (2001) Drug Alcohol Depend , vol.64 , Issue.1 , pp. 9-17
    • Winstock, A.R.1    Griffiths, P.2    Stewart, D.3
  • 89
    • 0142093099 scopus 로고    scopus 로고
    • Ecstasy use among college undergraduates: Gender, race and sexual identity
    • Boyd, C. J.; McCabe, S. E.; d'Arcy, H. Ecstasy use among college undergraduates: gender, race and sexual identity. J. Subst. Abuse Treat., 2003, 24 (3), 209-215.
    • (2003) J. Subst. Abuse Treat , vol.24 , Issue.3 , pp. 209-215
    • Boyd, C.J.1    McCabe, S.E.2    d'Arcy, H.3
  • 90
    • 33745910208 scopus 로고    scopus 로고
    • Patterns of simultaneous polysubstance use in drug using university students
    • Barrett, S. P.; Darredeau, C.; Pihl, R. O. Patterns of simultaneous polysubstance use in drug using university students. Hum. Psychopharmacol., 2006, 21 (4), 255-263.
    • (2006) Hum. Psychopharmacol , vol.21 , Issue.4 , pp. 255-263
    • Barrett, S.P.1    Darredeau, C.2    Pihl, R.O.3
  • 91
    • 70449111706 scopus 로고    scopus 로고
    • The variety of ecstasy/MDMA users: Results from the national epidemiologic survey on alcohol and related conditions
    • Wu, L. T.; Parrott, A. C.; Ringwalt, C. L.; Yang, C., Blazer, D. G. The variety of ecstasy/MDMA users: results from the national epidemiologic survey on alcohol and related conditions. Am. J. Addict., 2009, 18 (6), 452-461.
    • (2009) Am. J. Addict , vol.18 , Issue.6 , pp. 452-461
    • Wu, L.T.1    Parrott, A.C.2    Ringwalt, C.L.3    Yang, C.4    Blazer, D.G.5
  • 92
    • 12844288099 scopus 로고    scopus 로고
    • Alcoholic fatty liver: Its pathogenesis and mechanism of progression to inflammation and fibrosis
    • Lieber, C. S. Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis. Alcohol, 2004, 34 (1), 9-19.
    • (2004) Alcohol , vol.34 , Issue.1 , pp. 9-19
    • Lieber, C.S.1
  • 93
    • 39149123560 scopus 로고    scopus 로고
    • CYP2E1 and oxidative liver injury by alcohol
    • Lu, Y.; Cederbaum, A. I. CYP2E1 and oxidative liver injury by alcohol. Free Radic. Biol. Med., 2008, 44 (5), 723-738.
    • (2008) Free Radic. Biol. Med , vol.44 , Issue.5 , pp. 723-738
    • Lu, Y.1    Cederbaum, A.I.2
  • 95
    • 34548307195 scopus 로고    scopus 로고
    • Alcohol and cardiovascular health: The razor-sharp double-edged sword
    • O'Keefe, J. H.; Bybee, K. A.; Lavie, C. J. Alcohol and cardiovascular health: the razor-sharp double-edged sword. J. Am. Coll. Cardiol., 2007, 50 (11), 1009-1014.
    • (2007) J. Am. Coll. Cardiol , vol.50 , Issue.11 , pp. 1009-1014
    • O'Keefe, J.H.1    Bybee, K.A.2    Lavie, C.J.3
  • 96
    • 33751240099 scopus 로고    scopus 로고
    • Binge ethanol administration enhances the MDMA-induced long-term 5-HT neurotoxicity in rat brain
    • Izco, M.; Orio, L.; O'Shea, E.; Colado, M. I. Binge ethanol administration enhances the MDMA-induced long-term 5-HT neurotoxicity in rat brain. Psychopharmacology (Berl), 2007, 189 (4), 459-470.
    • (2007) Psychopharmacology (Berl) , vol.189 , Issue.4 , pp. 459-470
    • Izco, M.1    Orio, L.2    O'Shea, E.3    Colado, M.I.4
  • 97
    • 33645740155 scopus 로고    scopus 로고
    • A tale of two Es
    • Nutt, D. J. A tale of two Es. J. Psychopharmacol., 2006, 20 (3), 315-317.
    • (2006) J. Psychopharmacol , vol.20 , Issue.3 , pp. 315-317
    • Nutt, D.J.1
  • 101
    • 65549105425 scopus 로고    scopus 로고
    • Drug interaction between ethanol and 3,4-methylenedioxymethamphetamine (ecstasy)
    • Upreti, V. V.; Eddington, N. D.; Moon, K. H.; Song, B. J.; Lee, I. J. Drug interaction between ethanol and 3,4-methylenedioxymethamphetamine (ecstasy). Toxicol. Lett., 2009, 188 (2), 167-172.
    • (2009) Toxicol. Lett , vol.188 , Issue.2 , pp. 167-172
    • Upreti, V.V.1    Eddington, N.D.2    Moon, K.H.3    Song, B.J.4    Lee, I.J.5
  • 102
    • 68849095564 scopus 로고    scopus 로고
    • Ethanol increases the distribution of MDMA to the rat brain: Possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA
    • Hamida, S. B.; Tracqui, A.; de Vasconcelos, A. P.; Szwarc, E.; Lazarus, C.; Kelche, C.; Jones, B. C.; Cassel, J. C. Ethanol increases the distribution of MDMA to the rat brain: possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA. Int. J. Neuropsychopharmacol., 2009, 12 (6), 749-759.
    • (2009) Int. J. Neuropsychopharmacol , vol.12 , Issue.6 , pp. 749-759
    • Hamida, S.B.1    Tracqui, A.2    de Vasconcelos, A.P.3    Szwarc, E.4    Lazarus, C.5    Kelche, C.6    Jones, B.C.7    Cassel, J.C.8
  • 103
    • 33845776568 scopus 로고    scopus 로고
    • Alcohol-induced blood-brain barrier dysfunction is mediated via inositol 1,4,5-triphosphate receptor (IP3R)-gated intracellular calcium release
    • Haorah, J.; Knipe, B.; Gorantla, S.; Zheng, J.; Persidsky, Y. Alcohol-induced blood-brain barrier dysfunction is mediated via inositol 1,4,5-triphosphate receptor (IP3R)-gated intracellular calcium release. J. Neurochem., 2007, 100 (2), 324-336.
    • (2007) J. Neurochem , vol.100 , Issue.2 , pp. 324-336
    • Haorah, J.1    Knipe, B.2    Gorantla, S.3    Zheng, J.4    Persidsky, Y.5
  • 105
    • 0033863837 scopus 로고    scopus 로고
    • Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxynonenal-induced apoptosis of PC12 cells
    • Soh, Y.; Jeong, K. S.; Lee, I. J.; Bae, M. A.; Kim, Y. C.; Song, B. J. Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxynonenal-induced apoptosis of PC12 cells. Mol. Pharmacol., 2000, 58 (3), 535-541.
    • (2000) Mol. Pharmacol , vol.58 , Issue.3 , pp. 535-541
    • Soh, Y.1    Jeong, K.S.2    Lee, I.J.3    Bae, M.A.4    Kim, Y.C.5    Song, B.J.6
  • 106
    • 0141509963 scopus 로고    scopus 로고
    • Constitutive induction of p-Erk1/2 accompanied by reduced activities of protein phosphatases 1 and 2A and MKP3 due to reactive oxygen species during cellular senescence
    • Kim, H. S.; Song, M. C.; Kwak, I. H.; Park, T. J.; Lim, I. K. Constitutive induction of p-Erk1/2 accompanied by reduced activities of protein phosphatases 1 and 2A and MKP3 due to reactive oxygen species during cellular senescence. J. Biol. Chem., 2003, 278 (39), 37497-37510.
    • (2003) J. Biol. Chem , vol.278 , Issue.39 , pp. 37497-37510
    • Kim, H.S.1    Song, M.C.2    Kwak, I.H.3    Park, T.J.4    Lim, I.K.5
  • 107
    • 22544478126 scopus 로고    scopus 로고
    • Regulation of cys-based protein tyrosine phosphatases via reactive oxygen and nitrogen species in mast cells and basophils
    • Heneberg, P.; Dráber, P. Regulation of cys-based protein tyrosine phosphatases via reactive oxygen and nitrogen species in mast cells and basophils. Curr. Med. Chem., 2005, 12 (16), 1859-1871.
    • (2005) Curr. Med. Chem , vol.12 , Issue.16 , pp. 1859-1871
    • Heneberg, P.1    Dráber, P.2


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