Peroxynitrite inactivation of tyrosine hydroxylase: Mediation by sulfhydryl oxidation, not tyrosine nitration

Journal of Neuroscience

Volumn 19, Issue 23, 1999, Pages 10289-10294

  Kuhn, Donald M ^a   Aretha, Cheryl W ^a   Geddes, Timothy J ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dopamine; Neurotoxic amphetamines; Parkinson's disease; Peroxynitrite; Sulfhydryl oxidation; Tyrosine hydroxylase; Tyrosine nitration

Indexed keywords

AMPHETAMINE; DOPAMINE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; THIOL DERIVATIVE; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ARTICLE; CATALYSIS; DOPAMINERGIC NERVE CELL; ENZYME ACTIVITY; ENZYME INACTIVATION; NITRATION; NONHUMAN; OXIDATION; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

EID: 0033499889     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-23-10289.1999     Document Type: Article

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