Chronic exposure to MDMA (ecstasy) increases DNA damage in sperm and alters testes histopathology in male rats

Toxicology Letters

Volumn 191, Issue 1, 2009, Pages 40-46

  Barenys, Marta ^a   Macia, Nuria ^a   Camps, Lydia ^b   de Lapuente, Joaquin ^b   Gomez Catalan, Jesus ^a   Gonzalez Linares, Javier ^b   Borras, Miquel ^b   Rodamilans, Miguel ^a   Llobet, Juan M ^a  

^a School of Pharmacy   (Spain)

^b Barcelona Science Park   (Spain)

Author keywords

3,4 Methylenedioxymethamphetamine; Chronic administration; Ecstasy; Male fertility; MDMA; Rat

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; FEMALE; GENOTOXICITY; HEMATOLOGICAL PARAMETERS; HISTOPATHOLOGY; HORMONE DETERMINATION; LONG TERM EXPOSURE; MALE; MALE FERTILITY; MATING; NONHUMAN; PREGNANCY RATE; PRIORITY JOURNAL; RAT; SPERM; SPERMATOZOON MOTILITY; TESTIS ATROPHY; TESTIS DISEASE;

ANIMALS; DNA DAMAGE; DRINKING; EPIDIDYMIS; FEMALE; FERTILITY; FOLLICLE STIMULATING HORMONE; LUTEINIZING HORMONE; MALE; MICRONUCLEUS TESTS; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; ORGAN SIZE; PREGNANCY; RATS; SEXUAL BEHAVIOR, ANIMAL; SPERM COUNT; SPERMATIDS; SPERMATOZOA; TESTIS; TESTOSTERONE;

ANIMALIA; RATTUS;

EID: 70350578786     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.08.002     Document Type: Article

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