-
1
-
-
0028858556
-
Human IL-17: A novel cytokine derived from T cells
-
Yao, Z. et al. Human IL-17: a novel cytokine derived from T cells. J. Immunol. 155, 5483-5486 (1995).
-
(1995)
J. Immunol
, vol.155
, pp. 5483-5486
-
-
Yao, Z.1
-
2
-
-
0027215897
-
CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpes virus saimiri gene
-
Rouvier, E., Luciani, M. F., Mattei, M. G., Denizot, F. & Golstein, P. CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpes virus saimiri gene. J. Immunol. 150, 5445-5456 (1993).
-
(1993)
J. Immunol
, vol.150
, pp. 5445-5456
-
-
Rouvier, E.1
Luciani, M.F.2
Mattei, M.G.3
Denizot, F.4
Golstein, P.5
-
3
-
-
34547415613
-
Interleukin-17 in fashion, at last: Ten years after its description, its cellular source has been identified
-
Miossec, P. Interleukin-17 in fashion, at last: ten years after its description, its cellular source has been identified. Arthritis Rheum. 56, 2111-2115 (2007).
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2111-2115
-
-
Miossec, P.1
-
4
-
-
15844402155
-
T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines
-
Fossiez, F. et al. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J. Exp. Med. 183, 2593-2603 (1996).
-
(1996)
J. Exp. Med
, vol.183
, pp. 2593-2603
-
-
Fossiez, F.1
-
5
-
-
5644277476
-
Interleukin-17 family members and inflammation
-
Kolls, J. K. & Lindén, A. Interleukin-17 family members and inflammation. Immunity 21, 467-476 (2004).
-
(2004)
Immunity
, vol.21
, pp. 467-476
-
-
Kolls, J.K.1
Lindén, A.2
-
6
-
-
55149113836
-
The roles of IL-17A in inflammatory immune responses and host defense against pathogens
-
Iwakura, Y., Nakae, S., Saijo, S. & Ishigame, H. The roles of IL-17A in inflammatory immune responses and host defense against pathogens. Immunol. Rev. 226, 57-79 (2008).
-
(2008)
Immunol. Rev
, vol.226
, pp. 57-79
-
-
Iwakura, Y.1
Nakae, S.2
Saijo, S.3
Ishigame, H.4
-
7
-
-
0033134608
-
IL-17 in synovial fluids from patients with RA is a potent stimulator of osteoclastogenesis
-
Kotake, S. et al. IL-17 in synovial fluids from patients with RA is a potent stimulator of osteoclastogenesis. J. Clin. Invest. 103, 1345-1352 (1999).
-
(1999)
J. Clin. Invest
, vol.103
, pp. 1345-1352
-
-
Kotake, S.1
-
8
-
-
14944354879
-
Induction of cartilage damage by overexpression of T cell IL-17A in experimental arthritis in mice deficient in IL-1
-
Koenders, M. I. et al. Induction of cartilage damage by overexpression of T cell IL-17A in experimental arthritis in mice deficient in IL-1. Arthritis Rheum. 52, 975-983 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 975-983
-
-
Koenders, M.I.1
-
9
-
-
51349111163
-
An overview of IL-17 function and signaling
-
Gaffen, S. L. An overview of IL-17 function and signaling. Cytokine 43, 402-407 (2008).
-
(2008)
Cytokine
, vol.43
, pp. 402-407
-
-
Gaffen, S.L.1
-
10
-
-
33745297345
-
Cutting edge: Interleukin 17 signals through a heteromeric receptor complex
-
Toy, D. et al. Cutting edge: interleukin 17 signals through a heteromeric receptor complex. J. Immunol. 177, 36-39 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 36-39
-
-
Toy, D.1
-
11
-
-
34250667109
-
Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression
-
Maitra, A. et al. Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression. Proc. Natl Acad. Sci. USA 104, 7507-7511 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 7507-7511
-
-
Maitra, A.1
-
12
-
-
40449113569
-
+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood
-
+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood. J. Immunol. 180, 655-663 (2008).
-
(2008)
J. Immunol
, vol.180
, pp. 655-663
-
-
Zrioual, S.1
-
13
-
-
0033083111
-
-
H2 cells. J. Immunol. 162, 1246-1251 (1999).
-
H2 cells. J. Immunol. 162, 1246-1251 (1999).
-
-
-
-
14
-
-
27544490377
-
+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6, 1123-1132 (2005).
-
(2005)
Nat. Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
-
15
-
-
33744984785
-
-
H17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 24, 677-688 (2006).
-
H17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 24, 677-688 (2006).
-
-
-
-
17
-
-
33748588423
-
+ T helper cells
-
+ T helper cells. Cell 126, 1121-1133 (2006).
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, B.S.1
-
18
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
Aggarwal, S., Ghilardi, N., Xie, M. H., de Sauvage, F. J. & Gurney, A. L. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278, 1910-1914 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
de Sauvage, F.J.4
Gurney, A.L.5
-
19
-
-
33749318470
-
H17 cells and cooperatively enhance expression of antimicrobial peptides
-
H17 cells and cooperatively enhance expression of antimicrobial peptides. J. Exp. Med. 203, 2271-2279 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 2271-2279
-
-
Liang, S.C.1
-
20
-
-
59649086053
-
H17 cytokine IL-22 in collagen-induced arthritis in C57Bl/6 mice
-
H17 cytokine IL-22 in collagen-induced arthritis in C57Bl/6 mice. Arthritis Rheum. 60, 390-395 (2009).
-
(2009)
Arthritis Rheum
, vol.60
, pp. 390-395
-
-
Geboes, L.1
-
21
-
-
0035879192
-
IL-1 independent role of IL-17 in synovial inflammation and joint destruction during collagen induced arthritis
-
Lubberts, E. et al. IL-1 independent role of IL-17 in synovial inflammation and joint destruction during collagen induced arthritis. J. Immunol. 167, 1004-1013 (2001).
-
(2001)
J. Immunol
, vol.167
, pp. 1004-1013
-
-
Lubberts, E.1
-
22
-
-
0037333960
-
Interleukin-17 in rheumatoid arthritis: If T cells were to contribute to inflammation and destruction through synergy
-
Miossec, P. Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergy. Arthritis Rheum. 48, 594-601 (2003).
-
(2003)
Arthritis Rheum
, vol.48
, pp. 594-601
-
-
Miossec, P.1
-
23
-
-
33751521013
-
H17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
-
H17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J. Exp. Med. 203, 2673-2682 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 2673-2682
-
-
Sato, K.1
-
24
-
-
33750351338
-
Potential new targets in arthritis therapy: Interleukin (IL)-17 and its relations to tumour necrosis factor and IL-1 in experimental arthritis
-
Koenders, M. I., Joosten, L. A. & van den Berg, W. B. Potential new targets in arthritis therapy: interleukin (IL)-17 and its relations to tumour necrosis factor and IL-1 in experimental arthritis. Ann. Rheum. Dis. 65 (suppl. 3), iii29-iii33 (2006).
-
(2006)
Ann. Rheum. Dis
, vol.65
, Issue.SUPPL. 3
-
-
Koenders, M.I.1
Joosten, L.A.2
van den Berg, W.B.3
-
25
-
-
33646490259
-
Interleukin-17 acts independently of TNF-α under arthritic conditions
-
Koenders, M. I. et al. Interleukin-17 acts independently of TNF-α under arthritic conditions. J. Immunol. 176, 6262-6269 (2006).
-
(2006)
J. Immunol
, vol.176
, pp. 6262-6269
-
-
Koenders, M.I.1
-
26
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in Il-17 deficient mice
-
Nakae, S., Nambu, A., Sudo, K. & Iwakura, Y. Suppression of immune induction of collagen-induced arthritis in Il-17 deficient mice. J. Immunol. 171, 6173-6177 (2003).
-
(2003)
J. Immunol
, vol.171
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
28
-
-
1042267236
-
Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen induced arthritis reduces joint inflammation, cartilage destruction and bone erosion
-
Lubberts, E. et al. Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen induced arthritis reduces joint inflammation, cartilage destruction and bone erosion. Arthritis Rheum. 50, 650-659 (2004).
-
(2004)
Arthritis Rheum
, vol.50
, pp. 650-659
-
-
Lubberts, E.1
-
29
-
-
21244482587
-
Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1
-
Koenders, M. I. et al. Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1. Am. J. Pathol. 167, 141-149 (2005).
-
(2005)
Am. J. Pathol
, vol.167
, pp. 141-149
-
-
Koenders, M.I.1
-
30
-
-
57349165831
-
Shift from Toll-like receptor 2 (TLR2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production
-
Abdollahi-Roodsaz, S. et al. Shift from Toll-like receptor 2 (TLR2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production. Arthritis Rheum. 58, 3753-3764 (2008).
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3753-3764
-
-
Abdollahi-Roodsaz, S.1
-
31
-
-
55049118394
-
Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction
-
Ogura, H. et al. Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction. Immunity 29, 628-636 (2008).
-
(2008)
Immunity
, vol.29
, pp. 628-636
-
-
Ogura, H.1
-
32
-
-
33646417072
-
The IL-23/IL-17 axis in inflammation
-
Iwakura, Y. & Ishigame, H. The IL-23/IL-17 axis in inflammation. J. Clin. Invest. 116, 1218-1222 (2006).
-
(2006)
J. Clin. Invest
, vol.116
, pp. 1218-1222
-
-
Iwakura, Y.1
Ishigame, H.2
-
33
-
-
33846456970
-
H cells that cause autoimmune arthritis
-
H cells that cause autoimmune arthritis. J. Exp. Med. 204, 41-47 (2007).
-
(2007)
J. Exp. Med
, vol.204
, pp. 41-47
-
-
Hirota, K.1
-
34
-
-
0038623916
-
IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
-
Nakae, S. et al. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc. Natl Acad. Sci. USA 100, 5986-5990 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 5986-5990
-
-
Nakae, S.1
-
35
-
-
55849150906
-
H17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice
-
H17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice. Arthritis Rheum. 58, 3461-3470 (2008).
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3461-3470
-
-
Koenders, M.I.1
-
36
-
-
38149048556
-
Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis
-
Abdollahi-Roodsaz, S. et al. Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis. J. Clin. Invest. 118, 205-216 (2008).
-
(2008)
J. Clin. Invest
, vol.118
, pp. 205-216
-
-
Abdollahi-Roodsaz, S.1
-
37
-
-
34848840994
-
Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis
-
Abdollahi-Roodsaz, S. et al. Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis. Arthritis Rheum. 56, 2957-2967 (2007).
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2957-2967
-
-
Abdollahi-Roodsaz, S.1
-
38
-
-
0032939156
-
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
-
Chabaud, M. et al. Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum. 42, 963-970 (1999).
-
(1999)
Arthritis Rheum
, vol.42
, pp. 963-970
-
-
Chabaud, M.1
-
39
-
-
0034966563
-
The combination of tumor necrosis factor-α blockade with interleukin-1 and interleukin-17 blockade is more effective for controlling synovial inflammation and bone resorption in an ex vivo model
-
Chabaud, M. & Miossec, P. The combination of tumor necrosis factor-α blockade with interleukin-1 and interleukin-17 blockade is more effective for controlling synovial inflammation and bone resorption in an ex vivo model. Arthritis Rheum. 44, 1293-1303 (2001).
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1293-1303
-
-
Chabaud, M.1
Miossec, P.2
-
40
-
-
0035048597
-
-
Chabaud, M., Lubberts, E., Joosten, L., van den Berg, W. B. & Miossec, P. IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis. Arthritis Res. 3, 168-177 (2001).
-
Chabaud, M., Lubberts, E., Joosten, L., van den Berg, W. B. & Miossec, P. IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis. Arthritis Res. 3, 168-177 (2001).
-
-
-
-
41
-
-
33947617790
-
Effects on osteoclast and osteoblast activities in cultured mouse calvarial bones by synovial fluids from patients with a loose joint prothesis and from osteoarthritis patients
-
Andersson, M. K. et al. Effects on osteoclast and osteoblast activities in cultured mouse calvarial bones by synovial fluids from patients with a loose joint prothesis and from osteoarthritis patients. Arthritis Res. Ther. 9, R18 (2007).
-
(2007)
Arthritis Res. Ther
, vol.9
-
-
Andersson, M.K.1
-
43
-
-
58149214356
-
+ T cells
-
+ T cells. Immunity 30, 155-167 (2009).
-
(2009)
Immunity
, vol.30
, pp. 155-167
-
-
Wei, G.1
-
44
-
-
58149251898
-
Late developmental plasticity in the T helper 17 lineage
-
Lee, Y. K. et al. Late developmental plasticity in the T helper 17 lineage. Immunity 30, 92-107 (2009).
-
(2009)
Immunity
, vol.30
, pp. 92-107
-
-
Lee, Y.K.1
-
45
-
-
60549086638
-
-
H1 cells. Eur. J. Immunol. 39, 216-224 (2009).
-
H1 cells. Eur. J. Immunol. 39, 216-224 (2009).
-
-
-
-
46
-
-
67650650890
-
H1-like cells in NOD/SCID recipient mice
-
H1-like cells in NOD/SCID recipient mice. J. Clin. Invest. 119, 565-572 (2009).
-
(2009)
J. Clin. Invest
, vol.119
, pp. 565-572
-
-
Bending, D.1
-
47
-
-
33646349199
-
Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: A two-year prospective study (the DAMAGE study cohort)
-
Kirkham, B. W. et al. Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two-year prospective study (the DAMAGE study cohort). Arthritis Rheum. 54, 1122-1131 (2006).
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1122-1131
-
-
Kirkham, B.W.1
-
48
-
-
21644479222
-
Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal origin
-
Raza, K. et al. Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal origin. Arthritis Res. Ther. 7, R784-R795 (2005).
-
(2005)
Arthritis Res. Ther
, vol.7
-
-
Raza, K.1
-
49
-
-
50249164315
-
H17 cells predominate in the joints of patients with rheumatoid arthritis
-
H17 cells predominate in the joints of patients with rheumatoid arthritis. Ann. Rheum. Dis. 67, 1299-1304 (2008).
-
(2008)
Ann. Rheum. Dis
, vol.67
, pp. 1299-1304
-
-
Yamada, H.1
-
50
-
-
47249125726
-
Chronically inflamed human tissues are infiltrated by highly differentiated TH17 lymphocytes
-
Pène, J. et al. Chronically inflamed human tissues are infiltrated by highly differentiated TH17 lymphocytes. J. Immunol. 180, 7423-7430 (2008).
-
(2008)
J. Immunol
, vol.180
, pp. 7423-7430
-
-
Pène, J.1
-
51
-
-
40549138745
-
Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers
-
Nishala, K. et al. Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers. Arthritis Rheum. 58, 875-887 (2008).
-
(2008)
Arthritis Rheum
, vol.58
, pp. 875-887
-
-
Nishala, K.1
-
52
-
-
51049091033
-
-
H17 cells in rheumatoid arthritis. Arthritis Res. Ther. 10, R93 (2008).
-
H17 cells in rheumatoid arthritis. Arthritis Res. Ther. 10, R93 (2008).
-
-
-
-
55
-
-
51049122843
-
Interleukin-17 producing δ T cells increased in patients with active pulmonary tuberculosis
-
Peng, M. Y. et al. Interleukin-17 producing δ T cells increased in patients with active pulmonary tuberculosis. Cell. Mol. Immunol. 5, 203-208 (2008).
-
(2008)
Cell. Mol. Immunol
, vol.5
, pp. 203-208
-
-
Peng, M.Y.1
-
56
-
-
45449084802
-
-
Roark, C. L., Simonian, P. L., Fontenot, A. P., Born, W. K. & O'Brien, R. L. γδ T cells: an important source of IL-17. Curr. Opin. Immunol. 20, 353-357 (2008).
-
Roark, C. L., Simonian, P. L., Fontenot, A. P., Born, W. K. & O'Brien, R. L. γδ T cells: an important source of IL-17. Curr. Opin. Immunol. 20, 353-357 (2008).
-
-
-
-
57
-
-
58149384437
-
Critical role of ROR-γt in a new thymic pathway leading to IL-17 producing invariant NKT cell differentiation
-
Michel, M. L. et al. Critical role of ROR-γt in a new thymic pathway leading to IL-17 producing invariant NKT cell differentiation. Proc. Natl Acad. Sci. USA 105, 19845-19850 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 19845-19850
-
-
Michel, M.L.1
-
58
-
-
49249112420
-
IL-17 produced by Paneth cells drives TNF-induced shock
-
Takahashi, N. et al. IL-17 produced by Paneth cells drives TNF-induced shock. J. Exp. Med. 8, 1755-1761 (2008).
-
(2008)
J. Exp. Med
, vol.8
, pp. 1755-1761
-
-
Takahashi, N.1
-
59
-
-
58149231532
-
Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses
-
Ishigame, H. et al. Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity 30, 108-119 (2009).
-
(2009)
Immunity
, vol.30
, pp. 108-119
-
-
Ishigame, H.1
-
60
-
-
41449110468
-
H17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
-
H17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature 452, 773-776 (2008).
-
(2008)
Nature
, vol.452
, pp. 773-776
-
-
Milner, J.D.1
-
61
-
-
42249084849
-
H1 effector response can drive autoimmunity: Conditions of disease induction affect dominant effector category
-
H1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. J. Exp. Med. 205, 1517-1522 (2008).
-
(2008)
J. Exp. Med
, vol.205
, pp. 1517-1522
-
-
Luger, D.1
-
62
-
-
47949090745
-
Development of proteoglycan-induced arthritis is independent of IL-17
-
Doodes, P. D. et al. Development of proteoglycan-induced arthritis is independent of IL-17. J. Immunol. 181, 329-337 (2008).
-
(2008)
J. Immunol
, vol.181
, pp. 329-337
-
-
Doodes, P.D.1
-
63
-
-
35648946449
-
Amplifying elements of arthritis and joint destruction
-
Van den Berg, W. B., van Lent, P. L., Joosten, L. A., Abdollahi-Roodsaz, S. & Koenders, M. I. Amplifying elements of arthritis and joint destruction. Ann. Rheum. Dis. 66 (suppl. 3), iii45-iii48 (2007).
-
(2007)
Ann. Rheum. Dis
, vol.66
, Issue.SUPPL. 3
-
-
Van den Berg, W.B.1
van Lent, P.L.2
Joosten, L.A.3
Abdollahi-Roodsaz, S.4
Koenders, M.I.5
-
64
-
-
59549083038
-
Interleukin-17 as drug target in human disease
-
Ivanov, S. & Linden, A. Interleukin-17 as drug target in human disease. Trends Pharmacol. Sci. 30, 95-103 (2009).
-
(2009)
Trends Pharmacol. Sci
, vol.30
, pp. 95-103
-
-
Ivanov, S.1
Linden, A.2
-
66
-
-
70349926431
-
AIN457, an anti-IL-17 antibody, shows good safety and induces clinical responses in patients with active rheumatoid arthritis (RA) despite methotrexate therapy in a randomized, double-blind, proof-of-concept trial [abstract LB0002]
-
Durez, P. et al. AIN457, an anti-IL-17 antibody, shows good safety and induces clinical responses in patients with active rheumatoid arthritis (RA) despite methotrexate therapy in a randomized, double-blind, proof-of-concept trial [abstract LB0002]. Ann. Rheum. Dis. 68 (suppl. 3), 125 (2009).
-
(2009)
Ann. Rheum. Dis
, vol.68
, Issue.SUPPL. 3
, pp. 125
-
-
Durez, P.1
-
67
-
-
70349922234
-
-
Sloan-Lancaster, J., Genovese, M. C., Roberson, S. A. & van den Bosch, F. Safety, tolerability and evidence of efficacy of intravenous LY2439821 in patients with rheumatoid arthritis receiving background oral DMARDs [abstract OP-0160]. Ann. Rheum. Dis. 68 (suppl. 3), 123 (2009).
-
Sloan-Lancaster, J., Genovese, M. C., Roberson, S. A. & van den Bosch, F. Safety, tolerability and evidence of efficacy of intravenous LY2439821 in patients with rheumatoid arthritis receiving background oral DMARDs [abstract OP-0160]. Ann. Rheum. Dis. 68 (suppl. 3), 123 (2009).
-
-
-
-
68
-
-
0038011833
-
Evolving concepts of rheumatoid arthritis
-
Firestein, G. S. Evolving concepts of rheumatoid arthritis. Nature 423, 356-361 (2003).
-
(2003)
Nature
, vol.423
, pp. 356-361
-
-
Firestein, G.S.1
|