메뉴 건너뛰기




Volumn 5, Issue 5, 2010, Pages

Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; BOVINE SERUM ALBUMIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ESTRADIOL; ESTROGEN RECEPTOR; FLUORESCEIN ISOTHIOCYANATE; FULVESTRANT; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; CONJUGATED ESTROGEN; DENDRIMER; ESTRADIOL BOVINE SERUM ALBUMIN; ESTRADIOL-BOVINE SERUM ALBUMIN; ESTROGEN; NEUROPROTECTIVE AGENT;

EID: 77956285989     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009851     Document Type: Article
Times cited : (156)

References (70)
  • 1
    • 34247150317 scopus 로고    scopus 로고
    • Neurotrophic and neuroprotective actions of estrogen: Basic mechanisms and clinical implications
    • Brann DW, Dhandapani K, Wakade C, Mahesh VB, Khan MM (2007) Neurotrophic and neuroprotective actions of estrogen: basic mechanisms and clinical implications. Steroids 72: 381-405.
    • (2007) Steroids , vol.72 , pp. 381-405
    • Brann, D.W.1    Dhandapani, K.2    Wakade, C.3    Mahesh, V.B.4    Khan, M.M.5
  • 2
    • 3042805396 scopus 로고    scopus 로고
    • Stroke in the female: Role of biological sex and estrogen
    • Murphy SJ, McCullough LD, Smith JM (2004) Stroke in the female: role of biological sex and estrogen. ILAR J 45: 147-159.
    • (2004) ILAR J , vol.45 , pp. 147-159
    • Murphy, S.J.1    McCullough, L.D.2    Smith, J.M.3
  • 3
    • 18744384376 scopus 로고    scopus 로고
    • Influence of gender on baseline features and clinical outcomes among 17,370 patients with confirmed ischaemic stroke in the international stroke trial
    • Niewada M, Kobayashi A, Sandercock PA, Kaminski B, Czlonkowska A (2005) Influence of gender on baseline features and clinical outcomes among 17,370 patients with confirmed ischaemic stroke in the international stroke trial. Neuroepidemiology 24: 123-128.
    • (2005) Neuroepidemiology , vol.24 , pp. 123-128
    • Niewada, M.1    Kobayashi, A.2    Sandercock, P.A.3    Kaminski, B.4    Czlonkowska, A.5
  • 4
    • 0037629087 scopus 로고    scopus 로고
    • Sex differences in the clinical presentation, resource use, and 3-month outcome of acute stroke in Europe: Data from a multicenter multinational hospital-based registry
    • Di Carlo A, Lamassa M, Baldereschi M, Pracucci G, Basile AM, et al. (2003) Sex differences in the clinical presentation, resource use, and 3-month outcome of acute stroke in Europe: data from a multicenter multinational hospital-based registry. Stroke 34: 1114-1119.
    • (2003) Stroke , vol.34 , pp. 1114-1119
    • Di Carlo, A.1    Lamassa, M.2    Baldereschi, M.3    Pracucci, G.4    Basile, A.M.5
  • 5
    • 0037477428 scopus 로고    scopus 로고
    • Sex differences in first-ever acute stroke
    • Roquer J, Campello AR, Gomis M (2003) Sex differences in first-ever acute stroke. Stroke 34: 1581-1585.
    • (2003) Stroke , vol.34 , pp. 1581-1585
    • Roquer, J.1    Campello, A.R.2    Gomis, M.3
  • 6
    • 51649110188 scopus 로고    scopus 로고
    • Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation
    • Zhang QG, Wang R, Khan M, Mahesh V, Brann DW (2008) Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation. J Neurosci 28: 8430-8441.
    • (2008) J Neurosci , vol.28 , pp. 8430-8441
    • Zhang, Q.G.1    Wang, R.2    Khan, M.3    Mahesh, V.4    Brann, D.W.5
  • 7
    • 0030700217 scopus 로고    scopus 로고
    • Estrogens may reduce mortality and ischemic damage caused by middle cerebral artery occlusion in the female rat
    • Simpkins JW, Rajakumar G, Zhang YQ, Simpkins CE, Greenwald D, et al. (1997) Estrogens may reduce mortality and ischemic damage caused by middle cerebral artery occlusion in the female rat. J Neurosurg 87: 724-730.
    • (1997) J Neurosurg , vol.87 , pp. 724-730
    • Simpkins, J.W.1    Rajakumar, G.2    Zhang, Y.Q.3    Simpkins, C.E.4    Greenwald, D.5
  • 9
    • 0037450414 scopus 로고    scopus 로고
    • Estrogen prevents the loss of CA1 hippocampal neurons in gerbils after ischemic injury
    • Shughrue PJ, Merchenthaler I (2003) Estrogen prevents the loss of CA1 hippocampal neurons in gerbils after ischemic injury. Neuroscience 116: 851-861.
    • (2003) Neuroscience , vol.116 , pp. 851-861
    • Shughrue, P.J.1    Merchenthaler, I.2
  • 10
    • 0032536475 scopus 로고    scopus 로고
    • Effects of gender and estradiol treatment on focal brain ischemia
    • Zhang YQ, Shi J, Rajakumar G, Day AL, Simpkins JW (1998) Effects of gender and estradiol treatment on focal brain ischemia. Brain Res 784: 321-324.
    • (1998) Brain Res , vol.784 , pp. 321-324
    • Zhang, Y.Q.1    Shi, J.2    Rajakumar, G.3    Day, A.L.4    Simpkins, J.W.5
  • 11
    • 33644638521 scopus 로고    scopus 로고
    • Estrogen receptors and human disease
    • Deroo BJ, Korach KS (2006) Estrogen receptors and human disease. J Clin Invest 116: 561-570.
    • (2006) J Clin Invest , vol.116 , pp. 561-570
    • Deroo, B.J.1    Korach, K.S.2
  • 12
    • 0035180875 scopus 로고    scopus 로고
    • Invited review: Estrogens effects on the brain: Multiple sites and molecular mechanisms
    • McEwen BS (2001) Invited review: Estrogens effects on the brain: multiple sites and molecular mechanisms. J Appl Physiol 91: 2785-2801.
    • (2001) J Appl Physiol , vol.91 , pp. 2785-2801
    • McEwen, B.S.1
  • 13
    • 0035852657 scopus 로고    scopus 로고
    • Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury
    • Dubal DB, Zhu H, Yu J, Rau SW, Shughrue PJ, et al. (2001) Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury. Proc Natl Acad Sci U S A 98: 1952-1957.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 1952-1957
    • Dubal, D.B.1    Zhu, H.2    Yu, J.3    Rau, S.W.4    Shughrue, P.J.5
  • 14
    • 1342330571 scopus 로고    scopus 로고
    • Neuroprotection by estrogen in animal models of global and focal ischemia
    • Merchenthaler I, Dellovade TL, Shughrue PJ (2003) Neuroprotection by estrogen in animal models of global and focal ischemia. Ann N Y Acad Sci 1007: 89-100.
    • (2003) Ann N Y Acad Sci , vol.1007 , pp. 89-100
    • Merchenthaler, I.1    Dellovade, T.L.2    Shughrue, P.J.3
  • 15
    • 70449397081 scopus 로고    scopus 로고
    • Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation
    • Zhang QG, Raz L, Wang R, Han D, De Sevilla L, et al. (2009) Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation. J Neurosci 29: 13823-13836.
    • (2009) J Neurosci , vol.29 , pp. 13823-13836
    • Zhang, Q.G.1    Raz, L.2    Wang, R.3    Han, D.4    de Sevilla, L.5
  • 16
    • 22144493001 scopus 로고    scopus 로고
    • Estrogen can act via estrogen receptor alpha and beta to protect hippocampal neurons against global ischemia-induced cell death
    • Miller NR, Jover T, Cohen HW, Zukin RS, Etgen AM (2005) Estrogen can act via estrogen receptor alpha and beta to protect hippocampal neurons against global ischemia-induced cell death. Endocrinology 146: 3070-3079.
    • (2005) Endocrinology , vol.146 , pp. 3070-3079
    • Miller, N.R.1    Jover, T.2    Cohen, H.W.3    Zukin, R.S.4    Etgen, A.M.5
  • 17
    • 0033178294 scopus 로고    scopus 로고
    • Estradiol modulates bcl-2 in cerebral ischemia: A potential role for estrogen receptors
    • Dubal DB, Shughrue PJ, Wilson ME, Merchenthaler I, Wise PM (1999) Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors. J Neurosci 19: 6385-6393.
    • (1999) J Neurosci , vol.19 , pp. 6385-6393
    • Dubal, D.B.1    Shughrue, P.J.2    Wilson, M.E.3    Merchenthaler, I.4    Wise, P.M.5
  • 18
    • 24044441632 scopus 로고    scopus 로고
    • 17Beta-estradiol induced Ca2+influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: A potential initiation mechanism for estrogen-induced neuroprotection
    • Wu TW, Wang JM, Chen S, Brinton RD (2005) 17Beta-estradiol induced Ca2+influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: a potential initiation mechanism for estrogen-induced neuroprotection. Neuroscience 135: 59-72.
    • (2005) Neuroscience , vol.135 , pp. 59-72
    • Wu, T.W.1    Wang, J.M.2    Chen, S.3    Brinton, R.D.4
  • 19
    • 34548681666 scopus 로고    scopus 로고
    • Estrogen receptor alpha and beta differentially regulate intracellular Ca(2+) dynamics leading to ERK phosphorylation and estrogen neuroprotection in hippocampal neurons
    • Zhao L, Brinton RD (2007) Estrogen receptor alpha and beta differentially regulate intracellular Ca(2+) dynamics leading to ERK phosphorylation and estrogen neuroprotection in hippocampal neurons. Brain Res 1172: 48-59.
    • (2007) Brain Res , vol.1172 , pp. 48-59
    • Zhao, L.1    Brinton, R.D.2
  • 20
    • 0035478068 scopus 로고    scopus 로고
    • Estrogen and Bcl-2: Gene induction and effect of transgene in experimental stroke
    • Alkayed NJ, Goto S, Sugo N, Joh HD, Klaus J, et al. (2001) Estrogen and Bcl-2: gene induction and effect of transgene in experimental stroke. J Neurosci 21: 7543-7550.
    • (2001) J Neurosci , vol.21 , pp. 7543-7550
    • Alkayed, N.J.1    Goto, S.2    Sugo, N.3    Joh, H.D.4    Klaus, J.5
  • 22
    • 55549142974 scopus 로고    scopus 로고
    • Genetic increase in brain-derived neurotrophic factor levels enhances learning and memory
    • Nakajo Y, Miyamoto S, Nakano Y, Xue JH, Hori T, et al. (2008) Genetic increase in brain-derived neurotrophic factor levels enhances learning and memory. Brain Res 1241: 103-109.
    • (2008) Brain Res , vol.1241 , pp. 103-109
    • Nakajo, Y.1    Miyamoto, S.2    Nakano, Y.3    Xue, J.H.4    Hori, T.5
  • 24
    • 0034969952 scopus 로고    scopus 로고
    • Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex
    • Singh M (2001) Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex. Endocrine 14: 407-415.
    • (2001) Endocrine , vol.14 , pp. 407-415
    • Singh, M.1
  • 25
    • 0344097487 scopus 로고    scopus 로고
    • Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: Convergence of estrogen and neurotrophin signaling pathways
    • Singh M, Setalo G, Jr., Guan X, Warren M, Toran-Allerand CD (1999) Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: convergence of estrogen and neurotrophin signaling pathways. J Neurosci 19: 1179-1188.
    • (1999) J Neurosci , vol.19 , pp. 1179-1188
    • Singh, M.1    Setalo Jr, G.2    Guan, X.3    Warren, M.4    Toran-Allerand, C.D.5
  • 26
    • 0033118665 scopus 로고    scopus 로고
    • The mitogenactivated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons
    • Singer CA, Figueroa-Masot XA, Batchelor RH, Dorsa DM (1999) The mitogenactivated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons. J Neurosci 19: 2455-2463.
    • (1999) J Neurosci , vol.19 , pp. 2455-2463
    • Singer, C.A.1    Figueroa-Masot, X.A.2    Batchelor, R.H.3    Dorsa, D.M.4
  • 27
    • 33847062554 scopus 로고    scopus 로고
    • MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia
    • Jover-Mengual T, Zukin RS, Etgen AM (2007) MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia. Endocrinology 148: 1131-1143.
    • (2007) Endocrinology , vol.148 , pp. 1131-1143
    • Jover-Mengual, T.1    Zukin, R.S.2    Etgen, A.M.3
  • 28
    • 7944227783 scopus 로고    scopus 로고
    • 17 Beta-estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in rats
    • Choi YC, Lee JH, Hong KW, Lee KS (2004) 17 Beta-estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in rats. Fundam Clin Pharmacol 18: 547-557.
    • (2004) Fundam Clin Pharmacol , vol.18 , pp. 547-557
    • Choi, Y.C.1    Lee, J.H.2    Hong, K.W.3    Lee, K.S.4
  • 29
    • 33748030120 scopus 로고    scopus 로고
    • Akt inhibits MLK3/JNK3 signaling by inactivating Rac1: A protective mechanism against ischemic brain injury
    • Zhang QG, Wang XT, Han D, Yin XH, Zhang GY, et al. (2006) Akt inhibits MLK3/JNK3 signaling by inactivating Rac1: a protective mechanism against ischemic brain injury. J Neurochem 98: 1886-1898.
    • (2006) J Neurochem , vol.98 , pp. 1886-1898
    • Zhang, Q.G.1    Wang, X.T.2    Han, D.3    Yin, X.H.4    Zhang, G.Y.5
  • 30
    • 18144419427 scopus 로고    scopus 로고
    • Binding of estrogen receptor with estrogen conjugated to bovine serum albumin (BSA)
    • Taguchi Y, Koslowski M, Bodenner DL (2004) Binding of estrogen receptor with estrogen conjugated to bovine serum albumin (BSA). Nucl Recept 2: 5.
    • (2004) Nucl Recept , vol.2 , pp. 5
    • Taguchi, Y.1    Koslowski, M.2    Bodenner, D.L.3
  • 31
    • 33646255439 scopus 로고    scopus 로고
    • Estradiol and its membrane-impermeable conjugate estradiol-BSA inhibit tamoxifen-stimulated prolactin secretion in incubated rat pituitaries
    • Aguilar R, Bellido C, Garrido-Gracia JC, Alonso R, Sanchez-Criado JE (2006) Estradiol and its membrane-impermeable conjugate estradiol-BSA inhibit tamoxifen-stimulated prolactin secretion in incubated rat pituitaries. Reproduction 131: 763-769.
    • (2006) Reproduction , vol.131 , pp. 763-769
    • Aguilar, R.1    Bellido, C.2    Garrido-Gracia, J.C.3    Alonso, R.4    Sanchez-Criado, J.E.5
  • 32
    • 0001548401 scopus 로고    scopus 로고
    • Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: Studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells
    • Razandi M, Pedram A, Greene GL, Levin ER (1999) Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells. Mol Endocrinol 13: 307-319.
    • (1999) Mol Endocrinol , vol.13 , pp. 307-319
    • Razandi, M.1    Pedram, A.2    Greene, G.L.3    Levin, E.R.4
  • 33
    • 33344476520 scopus 로고    scopus 로고
    • Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action
    • Harrington WR, Kim SH, Funk CC, Madak-Erdogan Z, Schiff R, et al. (2006) Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action. Mol Endocrinol 20: 491-502.
    • (2006) Mol Endocrinol , vol.20 , pp. 491-502
    • Harrington, W.R.1    Kim, S.H.2    Funk, C.C.3    Madak-Erdogan, Z.4    Schiff, R.5
  • 34
    • 61849115783 scopus 로고    scopus 로고
    • 17betaestradiol and enriched environment accelerate cognitive recovery after focal brain ischemia
    • Soderstrom I, Strand M, Ingridsson AC, Nasic S, Olsson T. (2009) 17betaestradiol and enriched environment accelerate cognitive recovery after focal brain ischemia. Eur J Neurosci 29: 1215-1224.
    • (2009) Eur J Neurosci , vol.29 , pp. 1215-1224
    • Soderstrom, I.1    Strand, M.2    Ingridsson, A.C.3    Nasic, S.4    Olsson, T.5
  • 35
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • Morris R (1984) Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods 11: 47-60.
    • (1984) J Neurosci Methods , vol.11 , pp. 47-60
    • Morris, R.1
  • 37
    • 37349081370 scopus 로고    scopus 로고
    • Extranuclear steroid receptors: Nature and actions
    • Hammes SR, Levin ER (2007) Extranuclear steroid receptors: nature and actions. Endocr Rev 28: 726-741.
    • (2007) Endocr Rev , vol.28 , pp. 726-741
    • Hammes, S.R.1    Levin, E.R.2
  • 38
    • 34547928773 scopus 로고    scopus 로고
    • A conserved mechanism for steroid receptor translocation to the plasma membrane
    • Pedram A, Razandi M, Sainson RC, Kim JK, Hughes CC, et al. (2007) A conserved mechanism for steroid receptor translocation to the plasma membrane. J Biol Chem 282: 22278-22288.
    • (2007) J Biol Chem , vol.282 , pp. 22278-22288
    • Pedram, A.1    Razandi, M.2    Sainson, R.C.3    Kim, J.K.4    Hughes, C.C.5
  • 39
    • 18144392361 scopus 로고    scopus 로고
    • Requirements for estrogen receptor alpha membrane localization and function
    • Evinger AJ, 3rd, Levin ER (2005) Requirements for estrogen receptor alpha membrane localization and function. Steroids 70: 361-363.
    • (2005) Steroids , vol.70 , pp. 361-363
    • Evinger III, A.J.1    Levin, E.R.2
  • 40
    • 18744401066 scopus 로고    scopus 로고
    • Non-nuclear estrogen receptor beta and alpha in the hippocampus of male and female rats
    • Kalita K, Szymczak S, Kaczmarek L (2005) Non-nuclear estrogen receptor beta and alpha in the hippocampus of male and female rats. Hippocampus 15: 404-412.
    • (2005) Hippocampus , vol.15 , pp. 404-412
    • Kalita, K.1    Szymczak, S.2    Kaczmarek, L.3
  • 41
    • 0035863873 scopus 로고    scopus 로고
    • Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites
    • Milner TA, McEwen BS, Hayashi S, Li CJ, Reagan LP, et al. (2001) Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites. J Comp Neurol 429: 355-371.
    • (2001) J Comp Neurol , vol.429 , pp. 355-371
    • Milner, T.A.1    McEwen, B.S.2    Hayashi, S.3    Li, C.J.4    Reagan, L.P.5
  • 42
    • 0346022988 scopus 로고    scopus 로고
    • Subcellular localization of estrogen receptor beta in mouse hippocampus
    • Nishio M, Kuroki Y, Watanabe Y (2004) Subcellular localization of estrogen receptor beta in mouse hippocampus. Neurosci Lett 355: 109-112.
    • (2004) Neurosci Lett , vol.355 , pp. 109-112
    • Nishio, M.1    Kuroki, Y.2    Watanabe, Y.3
  • 43
    • 0033135265 scopus 로고    scopus 로고
    • Localization of estrogen receptor beta-immunoreactivity in astrocytes of the adult rat brain
    • Azcoitia I, Sierra A, Garcia-Segura LM (1999) Localization of estrogen receptor beta-immunoreactivity in astrocytes of the adult rat brain. Glia 26: 260-267.
    • (1999) Glia , vol.26 , pp. 260-267
    • Azcoitia, I.1    Sierra, A.2    Garcia-Segura, L.M.3
  • 44
    • 45849083496 scopus 로고    scopus 로고
    • Estrogen receptor alpha is expressed on the cell-surface of embryonic hypothalamic neurons
    • Gorosito SV, Lorenzo AG, Cambiasso MJ (2008) Estrogen receptor alpha is expressed on the cell-surface of embryonic hypothalamic neurons. Neuroscience 154: 1173-1177.
    • (2008) Neuroscience , vol.154 , pp. 1173-1177
    • Gorosito, S.V.1    Lorenzo, A.G.2    Cambiasso, M.J.3
  • 45
    • 63249111135 scopus 로고    scopus 로고
    • Role of estrogen receptor alpha in membrane-initiated signaling in neural cells: Interaction with IGF-1 receptor
    • Marin R, Diaz M, Alonso R, Sanz A, Arevalo MA, et al. (2009) Role of estrogen receptor alpha in membrane-initiated signaling in neural cells: interaction with IGF-1 receptor. J Steroid Biochem Mol Biol 114: 2-7.
    • (2009) J Steroid Biochem Mol Biol , vol.114 , pp. 2-7
    • Marin, R.1    Diaz, M.2    Alonso, R.3    Sanz, A.4    Arevalo, M.A.5
  • 46
    • 67449123067 scopus 로고    scopus 로고
    • Control of CNS neuronal excitability by estrogens via membrane-initiated signaling
    • Kelly MJ, Ronnekleiv OK (2009) Control of CNS neuronal excitability by estrogens via membrane-initiated signaling. Mol Cell Endocrinol 308: 17-25.
    • (2009) Mol Cell Endocrinol , vol.308 , pp. 17-25
    • Kelly, M.J.1    Ronnekleiv, O.K.2
  • 47
    • 72849152546 scopus 로고    scopus 로고
    • Estradiol-induced estrogen receptor-alpha trafficking
    • Bondar G, Kuo J, Hamid N, Micevych P (2009) Estradiol-induced estrogen receptor-alpha trafficking. J Neurosci 29: 15323-15330.
    • (2009) J Neurosci , vol.29 , pp. 15323-15330
    • Bondar, G.1    Kuo, J.2    Hamid, N.3    Micevych, P.4
  • 48
    • 3843059020 scopus 로고    scopus 로고
    • A membrane estrogen receptor mediates intracellular calcium release in astrocytes
    • Chaban VV, Lakhter AJ, Micevych P (2004) A membrane estrogen receptor mediates intracellular calcium release in astrocytes. Endocrinology 145: 3788-3795.
    • (2004) Endocrinology , vol.145 , pp. 3788-3795
    • Chaban, V.V.1    Lakhter, A.J.2    Micevych, P.3
  • 49
    • 33845590845 scopus 로고    scopus 로고
    • Role of astrocytes in estrogen-mediated neuroprotection
    • Dhandapani KM, Brann DW (2007) Role of astrocytes in estrogen-mediated neuroprotection. Exp Gerontol 42: 70-75.
    • (2007) Exp Gerontol , vol.42 , pp. 70-75
    • Dhandapani, K.M.1    Brann, D.W.2
  • 50
    • 18844376360 scopus 로고    scopus 로고
    • Astrocyte-derived transforming growth factor-{beta} mediates the neuroprotective effects of 17{beta}-estradiol: Involvement of nonclassical genomic signaling pathways
    • Dhandapani KM, Wade FM, Mahesh VB, Brann DW (2005) Astrocyte-derived transforming growth factor-{beta} mediates the neuroprotective effects of 17{beta}-estradiol: involvement of nonclassical genomic signaling pathways. Endocrinology 146: 2749-2759.
    • (2005) Endocrinology , vol.146 , pp. 2749-2759
    • Dhandapani, K.M.1    Wade, F.M.2    Mahesh, V.B.3    Brann, D.W.4
  • 54
    • 46149083441 scopus 로고    scopus 로고
    • Expression and intracellular distribution of the G protein-coupled receptor 30 in rat hippocampal formation
    • Matsuda K, Sakamoto H, Mori H, Hosokawa K, Kawamura A, et al. (2008) Expression and intracellular distribution of the G protein-coupled receptor 30 in rat hippocampal formation. Neurosci Lett 441: 94-99.
    • (2008) Neurosci Lett , vol.441 , pp. 94-99
    • Matsuda, K.1    Sakamoto, H.2    Mori, H.3    Hosokawa, K.4    Kawamura, A.5
  • 55
    • 70349649964 scopus 로고    scopus 로고
    • Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival
    • Liu S, Le May C, Wong WP, Ward RD, Clegg DJ, et al. (2009) Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival. Diabetes 58: 2292-2302.
    • (2009) Diabetes , vol.58 , pp. 2292-2302
    • Liu, S.1    Le May, C.2    Wong, W.P.3    Ward, R.D.4    Clegg, D.J.5
  • 56
    • 50649101049 scopus 로고    scopus 로고
    • Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors
    • Madak-Erdogan Z, Kieser KJ, Kim SH, Komm B, Katzenellenbogen JA, et al. (2008) Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors. Mol Endocrinol 22: 2116-2127.
    • (2008) Mol Endocrinol , vol.22 , pp. 2116-2127
    • Madak-Erdogan, Z.1    Kieser, K.J.2    Kim, S.H.3    Komm, B.4    Katzenellenbogen, J.A.5
  • 57
    • 4344667924 scopus 로고    scopus 로고
    • The membrane actions of estrogens can potentiate their lordosis behavior-facilitating genomic actions
    • Kow LM, Pfaff DW (2004) The membrane actions of estrogens can potentiate their lordosis behavior-facilitating genomic actions. Proc Natl Acad Sci U S A 101: 12354-12357.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 12354-12357
    • Kow, L.M.1    Pfaff, D.W.2
  • 58
    • 33846862008 scopus 로고    scopus 로고
    • Membrane-initiated actions of estrogens in neuroendocrinology: Emerging principles
    • Vasudevan N, Pfaff DW (2007) Membrane-initiated actions of estrogens in neuroendocrinology: emerging principles. Endocr Rev 28: 1-19.
    • (2007) Endocr Rev , vol.28 , pp. 1-19
    • Vasudevan, N.1    Pfaff, D.W.2
  • 59
    • 63649135792 scopus 로고    scopus 로고
    • Estradiol rescues neurons from global ischemia-induced cell death: Multiple cellular pathways of neuroprotection
    • Lebesgue D, Chevaleyre V, Zukin RS, Etgen AM (2009) Estradiol rescues neurons from global ischemia-induced cell death: multiple cellular pathways of neuroprotection. Steroids 74: 555-561.
    • (2009) Steroids , vol.74 , pp. 555-561
    • Lebesgue, D.1    Chevaleyre, V.2    Zukin, R.S.3    Etgen, A.M.4
  • 60
    • 64049093683 scopus 로고    scopus 로고
    • Pretreatment with a single estradiol-17beta bolus activates cyclic-AMP response element binding protein and protects CA1 neurons against global cerebral ischemia
    • Raval AP, Saul I, Dave KR, DeFazio RA, Perez-Pinzon MA, et al. (2009) Pretreatment with a single estradiol-17beta bolus activates cyclic-AMP response element binding protein and protects CA1 neurons against global cerebral ischemia. Neuroscience 160: 307-318.
    • (2009) Neuroscience , vol.160 , pp. 307-318
    • Raval, A.P.1    Saul, I.2    Dave, K.R.3    Defazio, R.A.4    Perez-Pinzon, M.A.5
  • 61
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard B, Hibi M, Wu IH, Barrett T, Su B, et al. (1994) JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76: 1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.H.3    Barrett, T.4    Su, B.5
  • 62
    • 54249119561 scopus 로고    scopus 로고
    • JNK signaling in apoptosis
    • Dhanasekaran DN, Reddy EP (2008) JNK signaling in apoptosis. Oncogene 27: 6245-6251.
    • (2008) Oncogene , vol.27 , pp. 6245-6251
    • Dhanasekaran, D.N.1    Reddy, E.P.2
  • 63
    • 13844262643 scopus 로고    scopus 로고
    • The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways
    • Guan QH, Pei DS, Zhang QG, Hao ZB, Xu TL, et al. (2005) The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways. Brain Res 1035: 51-59.
    • (2005) Brain Res , vol.1035 , pp. 51-59
    • Guan, Q.H.1    Pei, D.S.2    Zhang, Q.G.3    Hao, Z.B.4    Xu, T.L.5
  • 67
    • 57349198937 scopus 로고    scopus 로고
    • Spatial memory in the Morris water maze and activation of cyclic AMP response element-binding (CREB) protein within the mouse hippocampus
    • Porte Y, Buhot MC, Mons NE (2008) Spatial memory in the Morris water maze and activation of cyclic AMP response element-binding (CREB) protein within the mouse hippocampus. Learn Mem 15: 885-894.
    • (2008) Learn Mem , vol.15 , pp. 885-894
    • Porte, Y.1    Buhot, M.C.2    Mons, N.E.3
  • 68
    • 37049030994 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity
    • Lipsky RH, Marini AM (2007) Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity. Ann N Y Acad Sci 1122: 130-143.
    • (2007) Ann N Y Acad Sci , vol.1122 , pp. 130-143
    • Lipsky, R.H.1    Marini, A.M.2
  • 69
    • 68249117473 scopus 로고    scopus 로고
    • New insights into the role of brain-derived neurotrophic factor in synaptic plasticity
    • Waterhouse EG, Xu B (2009) New insights into the role of brain-derived neurotrophic factor in synaptic plasticity. Mol Cell Neurosci 42: 81-89.
    • (2009) Mol Cell Neurosci , vol.42 , pp. 81-89
    • Waterhouse, E.G.1    Xu, B.2
  • 70
    • 0030452360 scopus 로고    scopus 로고
    • Spatiotemporal Dynamics of CREB Phosphorylation: Transient versus Sustained Phosphorylation in the Developing Striatum
    • Liu F-C, Graybiel AM (1996) Spatiotemporal Dynamics of CREB Phosphorylation: Transient versus Sustained Phosphorylation in the Developing Striatum. Neuron 17: 1133-1144.
    • (1996) Neuron , vol.17 , pp. 1133-1144
    • Liu, F.-C.1    Graybiel, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.