Is CREB a key to neuronal survival?

Trends in Neurosciences

Volumn 23, Issue 2, 2000, Pages 48-53

  Walton, Marshall R ^a   Dragunow, Mike ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PROTEIN C FOS; TRANSCRIPTION FACTOR;

BRAIN ISCHEMIA; CELL SURVIVAL; DENTATE GYRUS; GENE EXPRESSION; GENETIC TRANSCRIPTION; GRANULE CELL; HIPPOCAMPUS; NERVE CELL; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

EID: 0034142085     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-2236(99)01500-3     Document Type: Note

References (61)

1. Schreiber S.S., Baudry M. Selective neuronal vulnerability in the hippocampus: a role for gene expression? Trends Neurosci. 18:1995;446-451.
2. Mattson M.P. Neuroprotective signal transduction: relevance to stroke. Neurosci. Biobehav. Rev. 21:1997;193-206.
3. Gonzalez G.A., Montminy M.R. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell. 59:1989;675-680.
4. Beiter-Johnson D., Millhorn D.E. Hypoxia induces phosphorylation of the cyclic AMP response element-binding protein by a novel signaling mechanism. J. Biol. Chem. 273:1998;19834-19839.
5. Brindle P.et al. Protein kinase A dependent activator in transcription factor CREB reveals new roles for CREM repressors. Nature. 364:1993;821-824.
6. Gonzalez G.A.et al. Characterization of motifs which are critical for activity of the cyclic AMP responsive transcription factor CREB. Mol. Cell. Biol. 11:1991;1306-1312.
7. Chrivia J.C.et al. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature. 365:1993;855-859.
8. Kwok R.P.S.et al. Nuclear protein CBP is a co-activator for the transcription factor CREB. Nature. 370:1994;223-226.
9. Arias J.et al. Activation of cyclic AMP and mitogen responsive genes relies on a common nuclear factor. Nature. 370:1994;226-229.
10. Lamph W.W.et al. Negative and positive regulation by transcription factor cAMP response element-binding protein is regulated by phosphorylation. Proc. Natl. Acad. Sci. U. S. A. 87:1990;4320-4324.
11. Masquilier D., Sassone-Corsi P. Transcriptional cross-talk: nuclear factors CREM and CREB bind to AP-1 sites and inhibit activation by Jun. J. Biol. Chem. 267:1992;22460-22466.
12. Moore A.N.et al. Neuronal activity increases the phosphorylation of the transcription factor cyclic AMP response element binding protein (CREB) in rat hippocampus and cortex. J. Biol. Chem. 271:1996;14214-14220.
13. Imaki J.et al. A developmental study of cyclic AMP-response element binding protein (CREB) by in situ hybridization histochemistry and immunocytochemistry in the rat neocortex. Brain Res. 651:1994;269-274.
14. Silva A.J.et al. CREB and memory. Annu. Rev. Neurosci. 21:1998;127-148.
15. Dragunow M., Preston K. The role of inducible transcription factors in apoptotic nerve cell death. Brain Res. Rev. 21:1995;1-28.
16. Beilharz E.J.et al. Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: evidence for apoptosis during selective neuronal loss. Mol. Brain Res. 29:1995;1-14.
17. Walton M.et al. Neuronal death and survival in two models of hypoxic-ischemic brain damage. Brain Res. Rev. 29:1999;137-168.
18. Dragunow M.et al. Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischemic brain injury? Mol. Brain Res. 18:1993;347-352.
19. Walton M.et al. The role of the cyclic AMP response element binding protein (CREB) in hypoxic-ischemic brain damage and repair. Mol. Brain Res. 43:1996;21-29.
20. Hu B.R.et al. Persistent phosphorylation of cyclic AMP responsive element binding protein and activating transcription factor 2 transcription factors following transient cerebral ischemia in rat brain. Neuroscience. 89:1999;437-452.
21. Tanaka K.et al. Immunohistochemical analysis of cyclic AMP response element binding protein phosphorylation in focal cerebral ischemia. Brain Res. 818:1999;520-526.
22. Walton M.et al. ATF-2 phosphorylation in apoptotic neuronal death. Mol. Brain Res. 63:1998;198-204.
23. Woodgate A.et al. Inducible transcription factor expression in a cell culture model of apoptosis. Mol. Brain Res. 66:1999;211-216.
24. Walton M.et al. CREB phosphorylation promotes nerve cell survival. J. Neurochem. 73:1999;1836-1842.
25. Yang Y.M.et al. Expression of dominant negative CREB reduces resistance to radiation of human melanoma cells. Oncogene. 12:1996;2223-2233.
26. Jean D.et al. CREB and its associated proteins act as survival factors for human melanoma cells. J. Biol. Chem. 273:1998;24884-24890.
27. Barton K.et al. Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant negative form of CREB. Nature. 379:1996;81-85.
28. Bussfeld D.et al. Expression of transcription factor genes after influenza A virus infection. Immunobiology. 198:1997;291-298.
29. Young D.et al. Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nat. Med. 5:1999;448-453.
30. Seki T., Arai Y. Highly polysialylated neural cell adhesion molecule (NCAM-H) is expressed by newly generated granule cells in the dentate gyrus of the adult rat. J. Neurosci. 13:1993;2351-2358.
31. Schmid R-S.et al. N-CAM stimulates the RAS-MAPK pathway and CREB phosphorylation in neuronal cells. J. Neurobiol. 38:1999;542-558.
32. Azizeh B.Y.et al. Cross-linking of N-CAM receptors on neurons induces programmed cell death. Brain Res. 796:1998;20-26.
33. Bonni A.et al. Serine-133 phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals. Mol. Cell. Neurosci. 6:1995;168-183.
34. Finkbeiner S.et al. CREB: a major mediator of neuronal neurotrophin responses. Neuron. 19:1997;1031-1047.
35. Shieh P.B.et al. Identification of a signaling pathway involved in calcium regulation of BDNF expression. Neuron. 20:1998;727-740.
36. Tao X.et al. Calcium influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron. 20:1998;709-726.
37. Goodman Y.et al. Estrogens attentuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta peptide toxicity in hippocampal neurons. J. Neurochem. 66:1996;1836-1844.
38. Green P.S.et al. 17 beta estradiol exerts neuroprotective effects on SK-N-SH cells. J. Neurosci. 17:1997;511-515.
39. Watters J.J., Dorsa D.M. Transcriptional effects of estrogen on neurotensin gene expression involve cAMP/protein kinase A-dependent signaling mechanisms. J. Neurosci. 18:1998;6672-6680.
40. Singh M.et al. The effect of ovariectomy and estradiol replacement on brain derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats. Endrocrinology. 136:1995;2320-2324.
41. Campard P.K.et al. PACAP type I receptor activation promotes cerebellar neuron survival through the cAMP/PKA signaling pathway. DNA Cell Biol. 16:1997;323-333.
42. Takei N.et al. Neurotrophic and neuroprotective effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on mesencephalic dopaminergic neurons. J. Neurosci. Res. 54:1998;698-706.
43. Tanaka J.et al. Neuronal protection from apoptosis by pituitary adenylate cyclase-activating polypeptide. Regul. Pept. 72:1997;1-8.
44. Villalba M., Journot L. Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway. J. Neurosci. 17:1997;83-90.
45. Hashimoto H.et al. Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: an in situ hybridization study. J. Comp. Neurol. 371:1996;567-577.
46. Dudek H.et al. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science. 275:1997;661-664.
47. Franke T.F.et al. PI3K: Downstream AKTion blocks apoptosis. Cell. 88:1997;435-437.
48. Kulik G.et al. Antiapoptotic signaling by the insulin-like growth factor 1 receptor, phosphatidylinositol-3-kinase and AKT. Mol. Cell. Biol. 17:1997;1595-1606.
49. Datta S.R.et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 91:1997;231-241.
50. del Peso L.et al. Interleukin 3-induced phosphorylation of BAD through the protein kinase Akt. Science. 278:1997;687-689.
51. Cardone M.H.et al. Regulation of cell death protease caspase 9 by phosphorylation. Science. 282:1998;1318-1321.
52. Du K., Montminy M. CREB is a regulatory target for the protein kinase Akt/PKB. J. Biol. Chem. 273:1998;32377-32379.
53. Yano S.et al. Calcium promotes cell survival through CaM-K kinase activation of the protein kinase B pathway. Nature. 396:1998;584-587.
54. Roberson E.D.et al. The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus. J. Neurosci. 19:1999;4337-4348.
55. Wilson B.E.et al. Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis. Mol. Cell. Biol. 16:1996;5546-5556.
56. Merry D.E., Korsmeyer S.J. Bcl-2 gene family in the nervous system. Annu. Rev. Neurosci. 20:1997;245-267.
57. Chen J.et al. Apoptosis repressor genes bcl-2 and bcl-x-long are expressed in the rat brain following global ischemia. J. Cereb. Blood Flow Metab. 17:1997;2-10.
58. Wand J-M.et al. The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB. Mol. Cell. Biol. 19:1999;6195-6206.
59. Pugazhenthi S.et al. Insulin-like growth factor 1-mediated activation of the transcription factor cAMP response element-binding protein in PC12 cells. J. Biol. Chem. 274:1999;2829-2837.
60. Hata T.et al. Attentuated c-fos mRNA induction after middle cerebral artery occlusion in CREB knock-out mice does not modulate focal ischemic injury. J. Cereb. Blood Flow Metab. 18:1998;1325-1335.
61. Bonni A.et al. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science. 286:1999;1358-1362.