17 β-estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in rats

Fundamental and Clinical Pharmacology

Volumn 18, Issue 5, 2004, Pages 547-557

  Choi, Yeoung Cheul ^a   Lee, Jeong Hyun ^a   Hong, Ki Whan ^a   Lee, Kyu Sup ^a  

^a Pusan National University School of Medicine   (South Korea)

Author keywords

17 estradiol; Apoptosis; Bax; Bcl 2; Cytochrome c; Ischemic brain damage; Middle cerebral artery occlusion

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME C; DNA FRAGMENT; ESTRADIOL; IBERIOTOXIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POTASSIUM CHANNEL BLOCKING AGENT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVATION; ENZYME RELEASE; IMMUNOHISTOCHEMISTRY; MALE; MEAN ARTERIAL PRESSURE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; WESTERN BLOTTING;

ANIMALS; BRAIN; BRAIN INFARCTION; BRAIN ISCHEMIA; CEREBRAL ARTERIAL DISEASES; CEREBRAL CORTEX; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INJECTIONS, INTRAPERITONEAL; MALE; NEUROPROTECTIVE AGENTS; PEPTIDES; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; POTASSIUM CHANNEL BLOCKERS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; PTEN PHOSPHOHYDROLASE; RATS; RATS, SPRAGUE-DAWLEY; TUMOR SUPPRESSOR PROTEINS;

EID: 7944227783     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2004.00284.x     Document Type: Article

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