Modulation of inflammasome activity for the treatment of auto-inflammatory disorders

Journal of Clinical Immunology

Volumn 30, Issue 4, 2010, Pages 485-490

  Naik, Edwina ^a   Dixit, Vishva M ^a  

^a GENENTECH INC   (United States)

Author keywords

Auto inflammatory disorder; Caspases; DAMP; IL 1 ; Inflammasome; NLR proteins; PAMP

Indexed keywords

ABSENT IN MELANOMA 2 INFLAMMASOME; AIM2 INFLAMMASOME; CANAKINUMAB; CASPASE; CRYOPYRIN; IMMUNOLOGIC AGENT; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; IPAF INFLAMMASONE; NUCLEOTIDE BINDING DOMAIN AND LEUCINE RICH REPEAT CONTAINING RECEPTOR; NUCLEOTIDE BINDING DOMAIN AND LEUCINE RICH REPEAT CONTAINING RECEPTOR 1; NUCLEOTIDE BINDING DOMAIN AND LEUCINE RICH REPEAT CONTAINING RECEPTOR 3 AGONIST; PROTEIN PYRIN; RECEPTOR PROTEIN; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; REGULATOR PROTEIN; RILONACEPT; UNCLASSIFIED DRUG; PATTERN RECOGNITION RECEPTOR;

ALZHEIMER DISEASE; ANTIINFLAMMATORY ACTIVITY; AUTOINFLAMMATORY DISEASE; AUTOPHAGY; CINCA SYNDROME; CROHN DISEASE; CYTOKINE PRODUCTION; FAMILIAL PERIODIC FEVER SYNDROME; GOUT; HUMAN; IMMUNOREGULATION; INFLAMMATION; INNATE IMMUNITY; NON INSULIN DEPENDENT DIABETES MELLITUS; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; REVIEW; RHEUMATOID ARTHRITIS; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; SECOND MESSENGER; HEREDITARY AUTOINFLAMMATORY DISEASES; IMMUNOLOGY; SIGNAL TRANSDUCTION;

HEREDITARY AUTOINFLAMMATORY DISEASES; HUMANS; IMMUNITY, INNATE; INFLAMMATION; INTERLEUKIN-1BETA; RECEPTORS, PATTERN RECOGNITION; SIGNAL TRANSDUCTION;

EID: 77956266431     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-010-9383-8     Document Type: Review

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