-
1
-
-
77957000392
-
DT-diaphorase
-
Ernster, L. DT-diaphorase. Methods Enzymol. 10:309-317 (1967).
-
(1967)
Methods Enzymol.
, vol.10
, pp. 309-317
-
-
Ernster, L.1
-
3
-
-
0025142668
-
Purification properties and function
-
Lind, C., E. Cadenas, P. Hochstein, and L. Ernster. Purification properties and function. Methods Enzymol. 186:287-301 (1990).
-
(1990)
Methods Enzymol.
, vol.186
, pp. 287-301
-
-
Lind, C.1
Cadenas, E.2
Hochstein, P.3
Ernster, L.4
-
4
-
-
0020464384
-
DT-diaphorase as a quinone reductase: A cellular control device against semiquinone and superoxide radical formation
-
Lind, C., P. Hochstein, and L. Ernster. DT-diaphorase as a quinone reductase: a cellular control device against semiquinone and superoxide radical formation. Arch. Biochem. Biophys. 216:178-185 (1982).
-
(1982)
Arch. Biochem. Biophys.
, vol.216
, pp. 178-185
-
-
Lind, C.1
Hochstein, P.2
Ernster, L.3
-
5
-
-
0020440918
-
The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes
-
Thor, H., M. T. Smith, P. Hartzell, G. Bellomo, S. A. Jewell, and S. Orrenius. The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. J. Biol. Chem. 257:12419-12425 (1982).
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 12419-12425
-
-
Thor, H.1
Smith, M.T.2
Hartzell, P.3
Bellomo, G.4
Jewell, S.A.5
Orrenius, S.6
-
6
-
-
0344915418
-
Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis
-
Talalay, P., M. J. De Long, and H. J. Prochaska. Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis. Proc. Natl. Acad. Sci. USA 85:8261-8265 (1988).
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 8261-8265
-
-
Talalay, P.1
De Long, M.J.2
Prochaska, H.J.3
-
7
-
-
0020017245
-
Elevation of quinone reductase activity by anticarcinogenic antioxidants
-
Talalay, P., and A. M. Benson. Elevation of quinone reductase activity by anticarcinogenic antioxidants. Adv. Enz. Reg. 20:287-300 (1981).
-
(1981)
Adv. Enz. Reg.
, vol.20
, pp. 287-300
-
-
Talalay, P.1
Benson, A.M.2
-
8
-
-
0019142866
-
Increase of NAD(P)H: Quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity
-
Benson, A. M., M. J. Hunkeler, and P. Talalay. Increase of NAD(P)H: quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity. Proc. Natl. Acad. Sci. USA 77:5216-5220 (1980).
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 5216-5220
-
-
Benson, A.M.1
Hunkeler, M.J.2
Talalay, P.3
-
9
-
-
0001923885
-
Mechanism of induction of NAD(P)H: Quinone reductase
-
Talalay, P., and H. J. Prochaska. Mechanism of induction of NAD(P)H: quinone reductase. Chem. Scripta 27A:61-66 (1987).
-
(1987)
Chem. Scripta
, vol.27 A
, pp. 61-66
-
-
Talalay, P.1
Prochaska, H.J.2
-
10
-
-
0025017521
-
Bone marrow stromal cell bioactivation and detoxification of the benzene metabolite hydroquinone: Comparison of macrophages and fibroblastoid cells
-
Thomas, D. J., A. Sadler, V. V. Subrahmanyam, D. Siegel, M. J. Reasor, D. Wierda, and D. Ross. Bone marrow stromal cell bioactivation and detoxification of the benzene metabolite hydroquinone: comparison of macrophages and fibroblastoid cells. Mol. Pharmacol. 37:255-262 (1990).
-
(1990)
Mol. Pharmacol.
, vol.37
, pp. 255-262
-
-
Thomas, D.J.1
Sadler, A.2
Subrahmanyam, V.V.3
Siegel, D.4
Reasor, M.J.5
Wierda, D.6
Ross, D.7
-
11
-
-
0000692532
-
Induced protection of adrenal cortex against 7,12 dimethylbenzanthracene: Influence of ethionine: induction of menadione reductase. Incorporation of thymidine H3
-
Huggins, C., and R. Fukunishi. Induced protection of adrenal cortex against 7,12 dimethylbenzanthracene: influence of ethionine: induction of menadione reductase. Incorporation of thymidine H3. J. Exp. Med. 119: 923-942 (1964).
-
(1964)
J. Exp. Med.
, vol.119
, pp. 923-942
-
-
Huggins, C.1
Fukunishi, R.2
-
12
-
-
1842324925
-
Uber die synthese von vitaminen der K2-reihe und von ubichinonen (aus methylnaphthochinon bzw. dimethoxymethylbenzochinon) in zellkulturen
-
Schiefer, H. G., and C. Martius. Uber die synthese von vitaminen der K2-reihe und von ubichinonen (aus methylnaphthochinon bzw. dimethoxymethylbenzochinon) in zellkulturen. Biochem. Z. 333:454-462 (1960).
-
(1960)
Biochem. Z.
, vol.333
, pp. 454-462
-
-
Schiefer, H.G.1
Martius, C.2
-
13
-
-
1842416679
-
Properties of the vitamin K dependent γ-glutamyl carboxylase from rat liver
-
Olson, R. E., A. L. Hall, C. Lee, and W. K. Kappel. Properties of the vitamin K dependent γ-glutamyl carboxylase from rat liver. Chem. Scripta 27A: 187-192 (1987).
-
(1987)
Chem. Scripta
, vol.27 A
, pp. 187-192
-
-
Olson, R.E.1
Hall, A.L.2
Lee, C.3
Kappel, W.K.4
-
14
-
-
0025195610
-
Vitamin K1 2,3-epoxide, and quinone reduction: Mechanism and inhibition
-
Preusch, P. C., and D. M. Smalley. Vitamin K1 2,3-epoxide, and quinone reduction: mechanism and inhibition. Free Rad. Res. Commun. 8:401-415 (1990).
-
(1990)
Free Rad. Res. Commun.
, vol.8
, pp. 401-415
-
-
Preusch, P.C.1
Smalley, D.M.2
-
15
-
-
0027306169
-
Isolation of x-ray inducible transcripts from radioresistant human melanoma cells
-
Boothman, D., M. Meyers, N. Fukunaga, and S. W. Lee. Isolation of x-ray inducible transcripts from radioresistant human melanoma cells. Proc. Natl. Acad. Sci. USA 90:7200-7204 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7200-7204
-
-
Boothman, D.1
Meyers, M.2
Fukunaga, N.3
Lee, S.W.4
-
16
-
-
9244256748
-
The role of DT-diaphorase in the maintenance of the reduced antioxidant form of coenzyme Q in membrane systems
-
Beyer, R. E., J. Segura-Aguilar, S. Di Bernardo, M. Cavazzoni, R. Fato, D. Fiorentini, M. Galli, M. Setti, L. Landi, and G. Lenaz. The role of DT-diaphorase in the maintenance of the reduced antioxidant form of coenzyme Q in membrane systems. Proc. Natl. Acad. Sci. USA 93:2528-2532 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2528-2532
-
-
Beyer, R.E.1
Segura-Aguilar, J.2
Di Bernardo, S.3
Cavazzoni, M.4
Fato, R.5
Fiorentini, D.6
Galli, M.7
Setti, M.8
Landi, L.9
Lenaz, G.10
-
17
-
-
0027318966
-
The role of metabolism in the antioxidant function of vitamin E
-
Liebler, D. C. The role of metabolism in the antioxidant function of vitamin E. Crit. Rev. Toxicol. 23:147-169 (1993).
-
(1993)
Crit. Rev. Toxicol.
, vol.23
, pp. 147-169
-
-
Liebler, D.C.1
-
18
-
-
0021919076
-
Inhibition of lipid peroxidation by α-tocopherolquinone and α-tocopherolhydroquinone
-
Bindoli, A., M. Valente, and L. Cavallini. Inhibition of lipid peroxidation by α-tocopherolquinone and α-tocopherolhydroquinone. Biochem. Int. 10: 753-761 (1985).
-
(1985)
Biochem. Int.
, vol.10
, pp. 753-761
-
-
Bindoli, A.1
Valente, M.2
Cavallini, L.3
-
19
-
-
0029035055
-
Is α-tocopherol a reservoir for α-tocopheryl hydroquinone?
-
Kohar, I., M. Baca, C. Suarna, R. Stocker, and P. T. Southwell-Keely. Is α-tocopherol a reservoir for α-tocopheryl hydroquinone? Free Rad. Biol. Med. 19:197-207 (1995).
-
(1995)
Free Rad. Biol. Med.
, vol.19
, pp. 197-207
-
-
Kohar, I.1
Baca, M.2
Suarna, C.3
Stocker, R.4
Southwell-Keely, P.T.5
-
20
-
-
0026751889
-
Reduction of α-tocopherolquinone to α-tocopherolhydruquinone in rat hepatocytes
-
Hayashi, T., A. Kanetoshi, M. Nakamura, M. Tamura, and H. Shirahama. Reduction of α-tocopherolquinone to α-tocopherolhydruquinone in rat hepatocytes. Biochem Pharmacol. 44:489-493 (1992).
-
(1992)
Biochem Pharmacol.
, vol.44
, pp. 489-493
-
-
Hayashi, T.1
Kanetoshi, A.2
Nakamura, M.3
Tamura, M.4
Shirahama, H.5
-
21
-
-
0029860030
-
Expression of human NAD(P)H:quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: Effect on the toxicity of antitumor quinones
-
Gustafson, D. L., H. D. Beall, E. M. Bolton, D. Ross, and C. A. Waldren. Expression of human NAD(P)H:quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: effect on the toxicity of antitumor quinones. Mol. Pharmacol. 50:728-735 (1996).
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 728-735
-
-
Gustafson, D.L.1
Beall, H.D.2
Bolton, E.M.3
Ross, D.4
Waldren, C.A.5
-
22
-
-
0028243181
-
Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases
-
Beall, H. D., R. T. Mulcahy, D. Siegel, R. D. Traver, N. W. Gibson, and D. Ross. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases. Cancer Res. 54:3196-3201 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 3196-3201
-
-
Beall, H.D.1
Mulcahy, R.T.2
Siegel, D.3
Traver, R.D.4
Gibson, N.W.5
Ross, D.6
-
23
-
-
0025688249
-
Metabolism of mitomycin C by DT-diaphorase: Role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells
-
Siegel, D., N. W. Gibson, P. C. Preusch, and D. Ross. Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells. Cancer Res. 50:7483-7489 (1990).
-
(1990)
Cancer Res.
, vol.50
, pp. 7483-7489
-
-
Siegel, D.1
Gibson, N.W.2
Preusch, P.C.3
Ross, D.4
-
24
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-275 (1951).
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
25
-
-
0029945977
-
Gas chromatography-mass spectrometry analysis of vitamin E and its oxidation products
-
Liebler, D. C., J. A. Burr, J. A., L. Philips, and A. J. L. Ham. Gas chromatography-mass spectrometry analysis of vitamin E and its oxidation products. Anal. Biochem. 236:27-34 (1996).
-
(1996)
Anal. Biochem.
, vol.236
, pp. 27-34
-
-
Liebler, D.C.1
Burr, J.A.2
Philips, L.3
Ham, A.J.L.4
-
26
-
-
0017872475
-
Microsomal lipid peroxidation
-
Buege, J. A., and S. D. Aust. Microsomal lipid peroxidation. Methods Enzymol. 52:302-310 (1977).
-
(1977)
Methods Enzymol.
, vol.52
, pp. 302-310
-
-
Buege, J.A.1
Aust, S.D.2
-
28
-
-
0025986826
-
Lipid peroxidation in AH-130 hepatoma cells enriched in vitro with arachidonic acid
-
Canuto, R. A., G. Muzio, M. E. Biocca, and M. U. Dianzani. Lipid peroxidation in AH-130 hepatoma cells enriched in vitro with arachidonic acid. Cancer Res. 51:4603-4608 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 4603-4608
-
-
Canuto, R.A.1
Muzio, G.2
Biocca, M.E.3
Dianzani, M.U.4
-
29
-
-
0019495032
-
Purification and properties of an NAD(P)H-dependent carbonyl reductase from human brain
-
Wermuth, B. Purification and properties of an NAD(P)H-dependent carbonyl reductase from human brain. J. Biol. Chem. 256:1206-1213 (1981).
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 1206-1213
-
-
Wermuth, B.1
-
30
-
-
0020073234
-
Regulation of cell division in a human glioma cell clone by arachidonic acid and α-tocopherolquinone
-
Liepkalns, V. A., C. Icard-Liepkalns, and D. G. Cornwell. Regulation of cell division in a human glioma cell clone by arachidonic acid and α-tocopherolquinone. Cancer Lett. 15:173-178 (1982).
-
(1982)
Cancer Lett.
, vol.15
, pp. 173-178
-
-
Liepkalns, V.A.1
Icard-Liepkalns, C.2
Cornwell, D.G.3
-
31
-
-
0021173769
-
Fatty acid metabolism and cell proliferation
-
Morisaki, N., J. A. Lindsey, J. M. Stitts, H. Zhang, and D. G. Cornwell. Fatty acid metabolism and cell proliferation. Lipids 19:381-394 (1984).
-
(1984)
Lipids
, vol.19
, pp. 381-394
-
-
Morisaki, N.1
Lindsey, J.A.2
Stitts, J.M.3
Zhang, H.4
Cornwell, D.G.5
-
32
-
-
0021913861
-
Antioxidant effects of tocopherols and their quinones
-
Lindsey, J. A., H. Zhang, H. Kaseki, N. Morisaki, T. Sato, and D. G. Cornwell. Antioxidant effects of tocopherols and their quinones. Lipids 20:151-157 (1985).
-
(1985)
Lipids
, vol.20
, pp. 151-157
-
-
Lindsey, J.A.1
Zhang, H.2
Kaseki, H.3
Morisaki, N.4
Sato, T.5
Cornwell, D.G.6
-
33
-
-
0028904009
-
Antioxidant and cytotoxic tocopheryl quinones in normal and cancer cells
-
Thornton, D. E., K. H. Jones, Z. Jiang, H. Zhang, G. Liu, and D. G. Cornwell. Antioxidant and cytotoxic tocopheryl quinones in normal and cancer cells. Free Rad. Biol. Med. 18:963-976 (1995).
-
(1995)
Free Rad. Biol. Med.
, vol.18
, pp. 963-976
-
-
Thornton, D.E.1
Jones, K.H.2
Jiang, Z.3
Zhang, H.4
Liu, G.5
Cornwell, D.G.6
-
34
-
-
0026444410
-
Pro- and antioxidant functions of quinones and quinone reductases in mammalian cells
-
Cadenas, E., P. Hochstein, and L. Ernster. Pro- and antioxidant functions of quinones and quinone reductases in mammalian cells. Adv. Enzymol. 65:97-146 (1992).
-
(1992)
Adv. Enzymol.
, vol.65
, pp. 97-146
-
-
Cadenas, E.1
Hochstein, P.2
Ernster, L.3
-
35
-
-
0024811681
-
Redox cycles of vitamin E: Hydrolysis and ascorbic acid dependent reduction of 8a-(alkyldioxy)tocopherones
-
Liebler, D. C., K. L. Kaysen, and T. A. Kennedy. Redox cycles of vitamin E: Hydrolysis and ascorbic acid dependent reduction of 8a-(alkyldioxy)tocopherones. Biochemistry 28:9772-9777 (1989).
-
(1989)
Biochemistry
, vol.28
, pp. 9772-9777
-
-
Liebler, D.C.1
Kaysen, K.L.2
Kennedy, T.A.3
-
36
-
-
0031016741
-
α-Tocopherol quinone is converted into vitamin E in man
-
Moore, A. N. J., and K. U. Ingold. α-Tocopherol quinone is converted into vitamin E in man. Free Rad. Biol. Med. 22:931-934 (1997).
-
(1997)
Free Rad. Biol. Med.
, vol.22
, pp. 931-934
-
-
Moore, A.N.J.1
Ingold, K.U.2
-
37
-
-
0026505943
-
NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: Characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity
-
Traver, R. D., T. Horikoshi, K. D. Danenburg, T. H. W. Stadibauer, P. V. Danenburg, D. Ross, and N. W. Gibson. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity. Cancer Res. 52:797-802 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 797-802
-
-
Traver, R.D.1
Horikoshi, T.2
Danenburg, K.D.3
Stadibauer, T.H.W.4
Danenburg, P.V.5
Ross, D.6
Gibson, N.W.7
-
38
-
-
0031021280
-
Characterization of a polymorphism in NAD(P)H: Quinone oxidoreductase (DT-diaphorase)
-
Traver, R. D., D. Siegel, H. D. Beall, R. M. Phillips, N. W. Gibson, W. A. Franklin, and D. Ross. Characterization of a polymorphism in NAD(P)H: quinone oxidoreductase (DT-diaphorase). Br. J. Cancer 75:69-75 (1997).
-
(1997)
Br. J. Cancer
, vol.75
, pp. 69-75
-
-
Traver, R.D.1
Siegel, D.2
Beall, H.D.3
Phillips, R.M.4
Gibson, N.W.5
Franklin, W.A.6
Ross, D.7
-
39
-
-
0029073531
-
Identification of an NAD(P)H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking
-
Rosvold, E. A., K. A. McGlynn, E. D. Lustbader, and K. H. Buetow. Identification of an NAD(P)H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking. Pharmacogenetics 5:199-206 (1995).
-
(1995)
Pharmacogenetics
, vol.5
, pp. 199-206
-
-
Rosvold, E.A.1
McGlynn, K.A.2
Lustbader, E.D.3
Buetow, K.H.4
-
40
-
-
0013469818
-
Incidence of a polymorphism in NAD(P)H: Quinone oxidoreductase (NQO1)
-
Traver, R. D., N. Rothman, M. T. Smith, S. Y. Yin, R. B. Hayes, G. L. Li, W. A. Franklin, and D. Ross. Incidence of a polymorphism in NAD(P)H: quinone oxidoreductase (NQO1) (Abstract). Proc. Amer. Assoc. Cancer Res. 37:1894 (1996).
-
(1996)
Proc. Amer. Assoc. Cancer Res.
, vol.37
, pp. 1894
-
-
Traver, R.D.1
Rothman, N.2
Smith, M.T.3
Yin, S.Y.4
Hayes, R.B.5
Li, G.L.6
Franklin, W.A.7
Ross, D.8
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