Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: Species comparison and structural changes with substrate binding and release

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 7, 2000, Pages 3177-3182

  Faig, Margarita ^a   Bianchet, Mario A ^a   Talalay, Paul ^a   Chen, Shiuan ^b   Winski, Shannon ^c   Ross, David ^c   Amzel, L Mario ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

Cancer; Chemoprotection; Chemotherapy; DT diaphorase

Indexed keywords

APOENZYME; DUROQUINONE; FLAVINE ADENINE NUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TYROSINE;

ARTICLE; BINDING SITE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME RELEASE; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; HUMAN; HYDROGEN BOND; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE;

ANIMALIA; ESCHERICHIA COLI;

EID: 0034724218     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.7.3177     Document Type: Article

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