Asymmetric synthesis of the α-D-galactosyl ceramide KRN7000 via an organocatalytic aldol reaction as key step

Synthesis

Volumn , Issue 17, 2010, Pages 2979-2984

  Enders, Dieter ^a   Terteryan, Violeta ^a   Paleek, Jií ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

galactosyl ceramide; aldol reaction; asymmetric synthesis; organocatalysis; proline

Indexed keywords

ALDOL REACTIONS; ASYMMETRIC SYNTHESIS; CERAMIDES; ORGANOCATALYSIS; PROLINE;

AMIDES; CATALYSIS; CONDENSATION REACTIONS; RATE CONSTANTS; REACTION KINETICS;

SYNTHESIS (CHEMICAL);

1 O (ALPHA GALACTOPYRANOSYL) 2 HEXACOSANOYLAMINO 1,3,4 OCTADECANETRIOL; 1 PENTADECANAL; 1,3 DIOXANE DERIVATIVE; 2,2 DIMETHYL 1,3 DIOXAN 5 ONE; ALDEHYDE; ALPHA GALACTOSYLCERAMIDE; FATTY ACID; GALACTOSE; HEXACOSANOIC ACID; PROLINE; UNCLASSIFIED DRUG;

ALDOL REACTION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; ENANTIOSELECTIVITY; IMMUNOSTIMULATION; INFRARED SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY;

EID: 77956032010     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0029-1218844     Document Type: Article

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