Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH

Journal of Organic Chemistry

Volumn 70, Issue 25, 2005, Pages 10260-10270

  Ndonye, Rachel M ^a   Izmirian, Douglas P ^a   Dunn, Matthew F ^a   Yu, Karl O A ^b   Porcelli, Steven A ^b   Khurana, Archana ^c   Kronenberg, Mitchell ^c   Richardson, Stewart K ^a   Howell, Amy R ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; ANTIGENS; BACTERIA; CELLS; IMMUNIZATION; PROTEINS; SYNTHESIS (CHEMICAL);

AUTOIMMUNE CONDITIONS; INFLAMMATORY CONDITIONS; PHYTOSPHINGOSINES; SPHINGANINE ANALOGUES;

AROMATIC COMPOUNDS;

1 (ALPHA GALACTOPYRANOSYL) 2 HEXACOSANOYLAMINOOCTADECAN 3 OL; 1 (ALPHA GALACTOPYRANOSYL) 2 TETRACOSANOYLAMINONONAN 3 OL; 1 O (ALPHA GALACTOPYRANOSYL) 2 HEXACOSANOYLAMINO 1,3,4 OCTADECANETRIOL; CD1D ANTIGEN; CYTOKINE; GALACTOSYLCERAMIDE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; PHYTOSPHINGOSINE; SPHINGANINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CYTOKINE PRODUCTION; DIABETES MELLITUS; DRUG STRUCTURE; DRUG SYNTHESIS; INFECTION; INFLAMMATION; MOUSE; MULTIPLE SCLEROSIS; NATURAL KILLER CELL; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIGEN PRESENTATION; CELLS, CULTURED; GALACTOSYLCERAMIDES; GLYCOLIPIDS; INTERFERON TYPE II; INTERLEUKIN-4; MICE; MICE, INBRED C57BL; SPHINGOSINE; SPLEEN; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES;

EID: 28744438007     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo051147h     Document Type: Article

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