α-S-GalCer: Synthesis and evaluation for iNKT cell stimulation

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 24, 2008, Pages 6374-6376

  Blauvelt, Marisa L ^a   Khalili, Maryam ^a   Jaung, Weonjoo ^b   Paulsen, Janet ^a   Anderson, Amy C ^a   Brian Wilson, S ^b   Howell, Amy R ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

S GalCer; CD1d; iNKT cells; KRN7000

Indexed keywords

1 O (ALPHA GALACTOPYRANOSYL) 2 HEXACOSANOYLAMINO 1,3,4 OCTADECANETRIOL; ALPHA GALACTOSYLCERAMIDE; CD1D ANTIGEN;

ALKYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL STIMULATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; IMMUNOSTIMULATION; INVARIANT NATURAL KILLER T CELL; MOUSE; NATURAL KILLER T CELL; NONHUMAN; SUBSTITUTION REACTION;

ANTINEOPLASTIC AGENTS; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; GALACTOSYLCERAMIDES; GLYCOLIPIDS; HUMANS; HYDROGEN BONDING; KILLER CELLS, NATURAL; MODELS, CHEMICAL; OXYGEN; SOLUBILITY; SULFHYDRYL COMPOUNDS;

EID: 56249131745     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.10.086     Document Type: Article

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