RCAI-17, 22, 24-26, 29, 31, 34-36, 38-40, and 88, the analogs of KRN7000 with a sulfonamide linkage: Their synthesis and bioactivity for mouse natural killer T cells to produce Th2-biased cytokines

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 19, 2008, Pages 8896-8906

  Tashiro, Takuya ^a   Hongo, Naomi ^b   Nakagawa, Ryusuke ^b   Seino, Ken ichiro ^b   Watarai, Hiroshi ^b   Ishii, Yasuyuki ^b   Taniguchi, Masaru ^b   Mori, Kenji ^a  

^a Research Center for Allergy and Immunology   (Japan)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

Author keywords

Galactosylceramides; Cytokines; NKT cell; OCH; Sulfonamide

Indexed keywords

1 O (ALPHA DEXTRO GALACTOPYRANOSYL) 2 (3 TOLUENESULFONAMIDO)OCTADECANE 3,4 DIOL; 1 O (ALPHA DEXTRO GALACTOPYRANOSYL) 2 (4 ACETAMIOBENZENESULFONAMIDO)OCTADECANE 3,4 DIOL; 1 O (ALPHA DEXTRO GALACTOPYRANOSYL) 2 (4 FLUOROBENZENESULFONAMIDO)OCTADECANE 3,4 DIOL; 1 O (ALPHA DEXTRO GALACTOPYRANOSYL) 2 (4 METHOXYBENZENESULFONAMIDO)OCTADECANE 3,4 DIOL; 1 O (ALPHA DEXTRO GALACTOPYRANOSYL) 2 (4 TERTBUTYLBENZENESULFONAMIDO)OCTADECANE 3,4 DIOL; 1 O (ALPHA DEXTRO GALACTOPYRANOSYL) 2 (4 TOLUENESULFONAMIDO)OCTADECANE 3,4 DIOL; 1 O (ALPHA DEXTRO GALACTOPYRANOSYL) 2 (HEXADECANESULFONAMIDO)OCTADECANE 3,4 DIOL; 1 O (ALPHA DEXTRO GALACTOPYRANOSYL) 2 (METHANESULFONAMIDO)OCTADECANE 3,4 DIOL; 1 O (ALPHA GALACTOPYRANOSYL) 2 HEXACOSANOYLAMINO 1,3,4 OCTADECANETRIOL; BENZENESULFONAMIDE DERIVATIVE; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 4; RCA 31; RCAI 17; RCAI 22; RCAI 24; RCAI 29; RCAI 34; RCAI 38; RCAI 88; SULFONAMIDE; TOLUENESULFONAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG SYNTHESIS; FEMALE; MOUSE; NATURAL KILLER T CELL; NONHUMAN; TH2 CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL ASSAY; CYTOKINES; FEMALE; GALACTOSYLCERAMIDES; INTERFERON-GAMMA; INTERLEUKIN-13; INTERLEUKIN-4; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; TH2 CELLS;

EID: 52949098710     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.08.060     Document Type: Article

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