Synergistic experimental/computational studies on arylazoenamine derivatives that target the bovine viral diarrhea virus RNA-dependent RNA polymerase

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 16, 2010, Pages 6055-6068

  Giliberti, Gabriele ^a   Ibba, Cristina ^a   Marongiu, Esther ^a   Loddo, Roberta ^a   Tonelli, Michele ^b   Boido, Vito ^b   Laurini, Erik ^c   Posocco, Paola ^c   Fermeglia, Maurizio ^c   Pricl, Sabrina ^c  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Anti BVDV agents; Arylazoenamines; BVDV resistant mutants; Molecular modeling

Indexed keywords

ANTIDIARRHEAL AGENT; ANTIVIRUS AGENT; ARYLAZOENAMINE DERIVATIVE; RNA DIRECTED RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS RNA;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; BOVINE DIARRHEA VIRUS; BOVINE VIRAL DIARRHEA; CYTOTOXICITY; DRUG DESIGN; DRUG ISOLATION; DRUG POTENTIATION; DRUG STRUCTURE; EXPERIMENTAL STUDY; IN VITRO STUDY; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; RNA VIRUS; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; AZO COMPOUNDS; BOVINE VIRUS DIARRHEA-MUCOSAL DISEASE; CATTLE; CELL LINE; CELL SURVIVAL; DIARRHEA VIRUSES, BOVINE VIRAL; DRUG DESIGN; DRUG RESISTANCE, VIRAL; HEMORRHAGIC SYNDROME, BOVINE; HUMANS; MODELS, MOLECULAR; RNA REPLICASE; VIRUS REPLICATION;

BOVINE VIRAL DIARRHEA VIRUS 1;

EID: 77955473941     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.06.065     Document Type: Article

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