N-sulfonylanthranilic acid derivatives as allosteric inhibitors of dengue viral RNA-dependent RNA polymerase

Journal of Medicinal Chemistry

Volumn 52, Issue 24, 2009, Pages 7934-7937

  Yin, Zheng ^a,c   Chen, Yen Liang ^a   Kondreddi, Ravinder Reddy ^a   Chan, Wai Ling ^a   Wang, Gang ^a   Ng, Ru Hui ^a   Lim, Joanne Y H ^a   Lee, Wan Yen ^a   Jeyaraj, Duraiswamy A ^a   Niyomrattanakit, Pornwaratt ^a   Wen, Daying ^a   Chao, Alex ^a   Glickman, J Fraser ^b   Voshol, Hans ^b   Mueller, Dieter ^b   Spanka, Carsten ^b   Dressler, Sigmar ^b   Nilar, Shahul ^a   Vasudevan, Subhash G ^a   Shi, Pei Yong ^a   Keller, Thomas H ^a   more..

^a NOVARTIS INSTITUTE FOR TROPICAL DISEASES   (Singapore)

^b NOVARTIS PHARMA AG   (Switzerland)

^c NANKAI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRANILIC ACID DERIVATIVE; ANTIVIRUS AGENT; N SULFONYLANTHRANILIC ACID DERIVATIVE; RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; BINDING SITE; DENGUE VIRUS; DRUG PROTEIN BINDING; STRUCTURE ACTIVITY RELATION;

ANTHRANILIC ACIDS; BINDING SITES; DENGUE VIRUS; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; RNA REPLICASE; STRUCTURE-ACTIVITY RELATIONSHIP; SULFINIC ACIDS;

EID: 73249137120     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm901044z     Document Type: Article

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