-
2
-
-
33750623679
-
KIT and PDGFRA mutations in gastrointestinal stromal tumors (GISTs)
-
DOI 10.1053/j.semdp.2006.08.006, PII S0740257006001420
-
Lasota J, Miettinen M. KIT and PDGFRA mutations in gastrointestinal stromal tumors (GISTs). Semin Diagn Pathol 2006;23:91-102. (Pubitemid 44692417)
-
(2006)
Seminars in Diagnostic Pathology
, vol.23
, Issue.2
, pp. 91-102
-
-
Lasota, J.1
Miettinen, M.2
-
3
-
-
49749122255
-
Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumors
-
Lasota J, Miettinen M. Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumors. Histopathology 2008;53:245-266
-
(2008)
Histopathology
, vol.53
, pp. 245-266
-
-
Lasota, J.1
Miettinen, M.2
-
4
-
-
34247855989
-
C-Kit/PDGFRA gene status alterations possibly related to primary imatinib resistance in gastrointestinal stromal tumors
-
DOI 10.1158/1078-0432.CCR-06-1745
-
Miselli FC, Casieri P, Negri T, et al. c-Kit/PDGFRA gene status alterations possibly related to primary imatinib resistance in gastrointestinal stromal tumors. Clin Cancer Res 2007;13:2369-2377 (Pubitemid 46698586)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.8
, pp. 2369-2377
-
-
Miselli, F.1
Casieri, P.2
Negri, T.3
Orsenigo, M.4
Lagonigro, M.S.5
Gronchi, A.6
Fiore, M.7
Casali, P.G.8
Bertulli, R.9
Carbone, A.10
Pierotti, M.A.11
Tamborini, E.12
Pilotti, S.13
-
5
-
-
70349533148
-
PDGFRA, PDGFRB, EGFR and downstream signalling activation in malignant peripheral nerve sheath tumour
-
Epub Feb 26 2009
-
Perrone F, Da Riva L, Orsenigo M, et al. PDGFRA, PDGFRB, EGFR and downstream signalling activation in malignant peripheral nerve sheath tumour. Neuro Oncol 2009. Epub Feb 26 2009.
-
(2009)
Neuro Oncol
-
-
Perrone, F.1
Da Riva, L.2
Orsenigo, M.3
-
6
-
-
20344393896
-
Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation
-
DOI 10.1158/1078-0432.CCR-04-2245
-
Antonescu CR, Besmer P, Guo T, et al. Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation. Clin Cancer Res 2005;11:4182-4190 (Pubitemid 40791584)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.11
, pp. 4182-4190
-
-
Antonescu, C.R.1
Besmer, P.2
Guo, T.3
Arkun, K.4
Hom, G.5
Koryotowski, B.6
Leversha, M.A.7
Jeffrey, P.D.8
Desantis, D.9
Singer, S.10
Brennan, M.F.11
Maki, R.G.12
Dematteo, R.P.13
-
7
-
-
33750595859
-
Molecular correlates of imatinib resistance in gastrointestinal stromal tumors
-
DOI 10.1200/JCO.2006.06.2265
-
Heinrich MC, Corless CL, Blanke CD, et al. Molecular correlates of imatinib resistance in gastrointestinal stromal tumors. J Clin Oncol 2006;24:4764-4774 (Pubitemid 46630941)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.29
, pp. 4764-4774
-
-
Heinrich, M.C.1
Corless, C.L.2
Blanke, C.D.3
Demetri, G.D.4
Joensuu, H.5
Roberts, P.J.6
Eisenberg, B.L.7
Von Mehren, M.8
Fletcher, C.D.M.9
Sandau, K.10
McDougall, K.11
Ou, W.-B.12
Chen, C.-J.13
Fletcher, J.A.14
-
8
-
-
50249092801
-
Heterogeneity of kinase inhibitor resistance mechanisms in GIST
-
Liegl B, Kepten I, Le C, et al. Heterogeneity of kinase inhibitor resistance mechanisms in GIST. J Pathol 2008;216:64-74.
-
(2008)
J Pathol
, vol.216
, pp. 64-74
-
-
Liegl, B.1
Kepten, I.2
Le, C.3
-
9
-
-
14944352767
-
Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants
-
DOI 10.1053/j.gastro.2004.11.020
-
Debiec-Rychter M, Cools J, Dumez H, et al. Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants. Gastroenterology 2005;128:270-279 (Pubitemid 40431080)
-
(2005)
Gastroenterology
, vol.128
, Issue.2
, pp. 270-279
-
-
Debiec-Rychter, M.1
Cools, J.2
Dumez, H.3
Sciot, R.4
Stul, M.5
Mentens, N.6
Vranckx, H.7
Wasag, B.8
Prenen, H.9
Roesel, J.10
Hagemeijer, A.11
Van Oosterom, A.12
Marynen, P.13
-
10
-
-
34548788543
-
Presence of homozygous KIT exon 11 mutations is strongly associated with malignant clinical behavior in gastrointestinal stromal tumors
-
Lasota J, vel Dobosz AJ, Wasag B, et al. Presence of homozygous KIT exon 11 mutations is strongly associated with malignant clinical behavior in gastrointestinal stromal tumors. Lab Invest 2007;87:1029-1041
-
(2007)
Lab Invest
, vol.87
, pp. 1029-1041
-
-
Lasota, J.1
Vel Dobosz, A.J.2
Wasag, B.3
-
11
-
-
34250335270
-
L576P KIT mutation in anal melanomas correlates with KIT protein expression and is sensitive to specific kinase inhibition
-
Antonescu CR, Busam KJ, Francone TD, et al. L576P KIT mutation in anal melanomas correlates with KIT protein expression and is sensitive to specific kinase inhibition. Int J Cancer 2007;121:257-264
-
(2007)
Int J Cancer
, vol.121
, pp. 257-264
-
-
Antonescu, C.R.1
Busam, K.J.2
Francone, T.D.3
-
12
-
-
0037263987
-
Gastrointestinal stromal tumors and leiomyomas in the dog: A histopathologic, immunohistochemical, and molecular genetic study of 50 cases
-
DOI 10.1354/vp.40-1-42
-
Frost D, Lasota J, Miettinen M. Gastrointestinal stromal tumors and leiomyomas in the dog: a histopathologic, immunohistochemical, and molecular genetic study of 50 cases. Vet Pathol 2003;40:42-54. (Pubitemid 38406113)
-
(2003)
Veterinary Pathology
, vol.40
, Issue.1
, pp. 42-54
-
-
Frost, D.1
Lasota, J.2
Miettinen, M.3
-
13
-
-
0032948780
-
Clustering of activating mutations in c-KIT's juxtamembrane coding region in canine mast cell neoplasms
-
DOI 10.1046/j.1523-1747.1999.00488.x
-
Ma Y, Longley BJ, Wang X, et al. Clustering of activating mutations in c-KIT's juxtamembrane coding region in canine mast cell neoplasms. J Invest Dermatol 1999;112:165-170 (Pubitemid 29061971)
-
(1999)
Journal of Investigative Dermatology
, vol.112
, Issue.2
, pp. 165-170
-
-
Ma, Y.1
Longley, B.J.2
Wang, X.3
Blount, J.L.4
Langley, K.5
Caughey, G.H.6
-
14
-
-
2542520755
-
Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs)
-
DOI 10.1038/sj.onc.1207525
-
Duensing A, Medeiros F, McConarty B, et al. Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs). Oncogene 2004;23:3999-4006. (Pubitemid 38747928)
-
(2004)
Oncogene
, vol.23
, Issue.22
, pp. 3999-4006
-
-
Duensing, A.1
Medeiros, F.2
McConarty, B.3
Joseph, N.E.4
Panigrahy, D.5
Singer, S.6
Fletcher, C.D.M.7
Demetri, G.D.8
Fletcher, J.A.9
-
15
-
-
31544459272
-
Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies
-
DOI 10.1158/0008-5472.CAN-05-2050
-
Schittenhelm MM, Shiraga S, Schroeder A, et al. Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies. Cancer Res 2006;66:473-481 (Pubitemid 43166056)
-
(2006)
Cancer Research
, vol.66
, Issue.1
, pp. 473-481
-
-
Schittenhelm, M.M.1
Shiraga, S.2
Schroeder, A.3
Corbin, A.S.4
Griffith, D.5
Lee, F.Y.6
Bokemeyer, C.7
Deininger, M.W.N.8
Druker, B.J.9
Heinrich, M.C.10
-
17
-
-
2942542387
-
Structural basis for the autoinhibition and STI-571 inhibition of c-kit tyrosine kinase
-
Mol CD, Dougan DR, Schneider TR, et al. Structural basis for the autoinhibition and STI-571 inhibition of c-kit tyrosine kinase. J Biol Chem 2004;279:31655-31663
-
(2004)
J Biol Chem
, vol.279
, pp. 31655-31663
-
-
Mol, C.D.1
Dougan, D.R.2
Schneider, T.R.3
-
18
-
-
23844553757
-
T315I-mutated Bcr-Abl in chronic myeloid leukemia and imatinib: Insights from a computational study
-
DOI 10.1158/1535-7163.MCT-05-0101
-
Pricl S, Fermeglia M, Ferrone M, et al. T315I-mutated Bcr-Abl in chronic myeloid leucemia and imatinib: insights from a computational study. Mol Cancer Ther 2005;4:1167-1174 (Pubitemid 41149564)
-
(2005)
Molecular Cancer Therapeutics
, vol.4
, Issue.8
, pp. 1167-1174
-
-
Pricl, S.1
Fermeglia, M.2
Ferrone, M.3
Tamborini, E.4
-
19
-
-
59749086693
-
T670X KIT mutations in gastrointestinal stromal tumors: Making sense of missense
-
Negri T, Pavan GM, Virdis E, et al. T670X KIT mutations in gastrointestinal stromal tumors: making sense of missense. J Natl Cancer Inst 2009;101:194-204.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 194-204
-
-
Negri, T.1
Pavan, G.M.2
Virdis, E.3
-
20
-
-
0032560959
-
Continuum solvent studies of the stability of DNA, RNA, and phosphoramidate-DNA helices
-
DOI 10.1021/ja981844+
-
Srinivasan J, Cheatham TE III, Cieplak P, et al. Continuum solvent studies of the stability of DNA, RNA, and phosphoramidate-DNA helices. J Am Chem Soc 1998;120:9401-9409 (Pubitemid 28452628)
-
(1998)
Journal of the American Chemical Society
, vol.120
, Issue.37
, pp. 9401-9409
-
-
Srinivasan, J.1
Cheatham III, T.E.2
Cieplak, P.3
Kollman, P.A.4
Case, D.A.5
|