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Volumn 77, Issue 9, 2003, Pages 5401-5414

Protein-protein interactions between hepatitis C virus nonstructural proteins

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 5A; PROTEIN NS2; PROTEIN NS4A; PROTEIN NS4B; PROTEIN NS5B; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 0037404536     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.9.5401-5414.2003     Document Type: Article
Times cited : (162)

References (97)
  • 2
    • 0035138086 scopus 로고    scopus 로고
    • Specific interaction of hepatitis C virus protease/helicase NS3 with the 3′-terminal sequences of viral positive- and negative-strand RNA
    • Banerjee, R., and A. Dasgupta. 2001. Specific interaction of hepatitis C virus protease/helicase NS3 with the 3′-terminal sequences of viral positive- and negative-strand RNA. J. Virol. 75:1708-1721.
    • (2001) J. Virol. , vol.75 , pp. 1708-1721
    • Banerjee, R.1    Dasgupta, A.2
  • 3
    • 0027287798 scopus 로고
    • Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions
    • Bartenschlager, R., L. Ahlborn-Laake, J. Mous, and H. Jacobsen. 1993. Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions. J. Virol. 67:3835-3844.
    • (1993) J. Virol. , vol.67 , pp. 3835-3844
    • Bartenschlager, R.1    Ahlborn-Laake, L.2    Mous, J.3    Jacobsen, H.4
  • 4
    • 0028241489 scopus 로고
    • Kinetic and structural analyses of hepatitis C virus polyprotein processing
    • Bartenschlager, R., L. Ahlborn-Laake, J. Mous, and H. Jacobsen. 1994. Kinetic and structural analyses of hepatitis C virus polyprotein processing. J. Virol. 68:5045-5055.
    • (1994) J. Virol. , vol.68 , pp. 5045-5055
    • Bartenschlager, R.1    Ahlborn-Laake, L.2    Mous, J.3    Jacobsen, H.4
  • 6
    • 0028820118 scopus 로고
    • Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation
    • Bartenschlager, R., V. Lohmann, T. Wilkinson, and J. O. Koch. 1995. Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation. J. Virol. 69:7519-7528.
    • (1995) J. Virol. , vol.69 , pp. 7519-7528
    • Bartenschlager, R.1    Lohmann, V.2    Wilkinson, T.3    Koch, J.O.4
  • 7
    • 0030051777 scopus 로고    scopus 로고
    • Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus
    • Behrens, S. E., L. Tomei, and R. De Francesco. 1996. Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus. EMBO J. 15:12-22.
    • (1996) EMBO J. , vol.15 , pp. 12-22
    • Behrens, S.E.1    Tomei, L.2    De Francesco, R.3
  • 8
    • 0031687438 scopus 로고    scopus 로고
    • Intracellular localization of poliovirus plus- and minus-strand RNA visualized by strand-specific fluorescent in situ hybridization
    • Bolten, R., D. Egger, R. Gosert, G. Schaub, L. Landmann, and K. Bienz. 1998. Intracellular localization of poliovirus plus- and minus-strand RNA visualized by strand-specific fluorescent in situ hybridization. J. Virol. 72:8578-8585.
    • (1998) J. Virol. , vol.72 , pp. 8578-8585
    • Bolten, R.1    Egger, D.2    Gosert, R.3    Schaub, G.4    Landmann, L.5    Bienz, K.6
  • 9
    • 0037040923 scopus 로고    scopus 로고
    • An amino-terminal amphipathic alphahelix mediates membrane association of the hepatitis C virus nonstructural protein 5A
    • Brass, V., E. Bieck, R. Montserret, B. Wolk, J. A. Hellings, H. E. Blum, F. Penin, and D. Moradpour. 2002. An amino-terminal amphipathic alphahelix mediates membrane association of the hepatitis C virus nonstructural protein 5A. J. Biol. Chem. 277:8130-8139.
    • (2002) J. Biol. Chem. , vol.277 , pp. 8130-8139
    • Brass, V.1    Bieck, E.2    Montserret, R.3    Wolk, B.4    Hellings, J.A.5    Blum, H.E.6    Penin, F.7    Moradpour, D.8
  • 11
    • 0029977774 scopus 로고    scopus 로고
    • Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli
    • Chartier, C., E. Degryse, M. Gantzer, A. Dieterle, A. Pavirani, and M. Mehtali. 1996. Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli. J. Virol. 70:4805-4810.
    • (1996) J. Virol. , vol.70 , pp. 4805-4810
    • Chartier, C.1    Degryse, E.2    Gantzer, M.3    Dieterle, A.4    Pavirani, A.5    Mehtali, M.6
  • 12
    • 0030595329 scopus 로고    scopus 로고
    • Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly
    • Chen, P., and M. Hochstrasser. 1996. Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly. Cell 86:961-972.
    • (1996) Cell , vol.86 , pp. 961-972
    • Chen, P.1    Hochstrasser, M.2
  • 13
    • 0032798689 scopus 로고    scopus 로고
    • Specific interaction between the hepatitis C virus NS5B RNA polymerase and the 3′ end of the viral RNA
    • Cheng, J. C., M. F. Chang, and S. C. Chang. 1999. Specific interaction between the hepatitis C virus NS5B RNA polymerase and the 3′ end of the viral RNA. J. Virol. 73:7044-7049.
    • (1999) J. Virol. , vol.73 , pp. 7044-7049
    • Cheng, J.C.1    Chang, M.F.2    Chang, S.C.3
  • 14
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Choo, Q. L., G. Kuo, A. J. Weiner, L. R. Overby, D. W. Bradley, and M. Houghton. 1989. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244:359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 15
    • 0036100578 scopus 로고    scopus 로고
    • Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex
    • Egger, D., B. Wolk, R. Gosert, L. Bianchi, H. E. Blum, D. Moradpour, and K. Bienz. 2002. Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex. J. Virol. 76:5974-5984.
    • (2002) J. Virol. , vol.76 , pp. 5974-5984
    • Egger, D.1    Wolk, B.2    Gosert, R.3    Bianchi, L.4    Blum, H.E.5    Moradpour, D.6    Bienz, K.7
  • 16
    • 0029161576 scopus 로고
    • Comparison of fulllength sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region
    • Enomoto, N., I. Sakuma, Y. Asahina, M. Kurosaki, T. Murakami, C. Yamamoto, N. Izumi, F. Marumo, and C. Sato. 1995. Comparison of fulllength sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region. J. Clin. Investig. 96:224-230.
    • (1995) J. Clin. Investig. , vol.96 , pp. 224-230
    • Enomoto, N.1    Sakuma, I.2    Asahina, Y.3    Kurosaki, M.4    Murakami, T.5    Yamamoto, C.6    Izumi, N.7    Marumo, F.8    Sato, C.9
  • 18
    • 0029092610 scopus 로고
    • Correlation of two-hybrid affinity data with in vitro measurements
    • Estojak, J., R. Brent, and E. A. Golemis. 1995. Correlation of two-hybrid affinity data with in vitro measurements. Mol. Cell. Biol. 15:5820-5829.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5820-5829
    • Estojak, J.1    Brent, R.2    Golemis, E.A.3
  • 19
    • 0028851296 scopus 로고
    • An amino-terminal domain of the hepatitis C virus NS3 protease is essential for interaction with NS4A
    • Failla, C., L. Tomei, and R. De Francesco. 1995. An amino-terminal domain of the hepatitis C virus NS3 protease is essential for interaction with NS4A. J. Virol. 69:1769-1777.
    • (1995) J. Virol. , vol.69 , pp. 1769-1777
    • Failla, C.1    Tomei, L.2    De Francesco, R.3
  • 20
    • 0032902564 scopus 로고    scopus 로고
    • Characterization of soluble hepatitis C virus RNA-dependent RNA polymerase expressed in Escherichia coli
    • Ferrari, E., J. Wright-Minogue, J. W. Fang, B. M. Baroudy, J. Y. Lau, and Z. Hong. 1999. Characterization of soluble hepatitis C virus RNA-dependent RNA polymerase expressed in Escherichia coli. J. Virol. 73:1649-1654.
    • (1999) J. Virol. , vol.73 , pp. 1649-1654
    • Ferrari, E.1    Wright-Minogue, J.2    Fang, J.W.3    Baroudy, B.M.4    Lau, J.Y.5    Hong, Z.6
  • 21
    • 0028568056 scopus 로고
    • Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators
    • Finley, R. L., Jr., and R. Brent. 1994. Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators. Proc. Natl. Acad. Sci. USA 91:12980-12984.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12980-12984
    • Finley R.L., Jr.1    Brent, R.2
  • 23
    • 0344765507 scopus 로고    scopus 로고
    • Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: A potential mechanism of interferon resistance
    • Gale, M. J., Jr., M. J. Korth, and M. G. Katze. 1998. Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: a potential mechanism of interferon resistance. Clin. Diagn. Virol. 10:157-162.
    • (1998) Clin. Diagn. Virol. , vol.10 , pp. 157-162
    • Gale M.J., Jr.1    Korth, M.J.2    Katze, M.G.3
  • 24
    • 0343924357 scopus 로고    scopus 로고
    • Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein
    • Gale, M. J., Jr., M. J. Korth, N. M. Tang, S. L. Tan, D. A. Hopkins, T. E. Dever, S. J. Polyak, D. R. Gretch, and M. G. Katze. 1997. Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein. Virology 230:217-227.
    • (1997) Virology , vol.230 , pp. 217-227
    • Gale M.J., Jr.1    Korth, M.J.2    Tang, N.M.3    Tan, S.L.4    Hopkins, D.A.5    Dever, T.E.6    Polyak, S.J.7    Gretch, D.R.8    Katze, M.G.9
  • 28
    • 0027414062 scopus 로고
    • Characterization of the hepatitis C virus-encoded serine proteinase: Determination of proteinase-dependent polyprotein cleavage sites
    • Grakoui, A., D. W. McCourt, C. Wychowski, S. M. Feinstone, and C. M. Rice. 1993. Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J. Virol. 67:2832-2843.
    • (1993) J. Virol. , vol.67 , pp. 2832-2843
    • Grakoui, A.1    McCourt, D.W.2    Wychowski, C.3    Feinstone, S.M.4    Rice, C.M.5
  • 29
    • 0027476809 scopus 로고
    • Expression and identification of hepatitis C virus polyprotein cleavage products
    • Grakoui, A., C. Wychowski, C. Lin, S. M. Feinstone, and C. M. Rice. 1993. Expression and identification of hepatitis C virus polyprotein cleavage products. J. Virol. 67:1385-1395.
    • (1993) J. Virol. , vol.67 , pp. 1385-1395
    • Grakoui, A.1    Wychowski, C.2    Lin, C.3    Feinstone, S.M.4    Rice, C.M.5
  • 30
    • 0025991559 scopus 로고
    • Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis
    • Hijikata, M., N. Kato, Y. Ootsuyama, M. Nakagawa, and K. Shimotohno. 1991. Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc. Natl. Acad. Sci. USA 88:5547-5551.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5547-5551
    • Hijikata, M.1    Kato, N.2    Ootsuyama, Y.3    Nakagawa, M.4    Shimotohno, K.5
  • 31
    • 0027163740 scopus 로고
    • Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus
    • Hijikata, M., H. Mizushima, T. Akagi, S. Mori, N. Kakiuchi, N. Kato, T. Tanaka, K. Kimura, and K. Shimotohno. 1993. Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. J. Virol. 67:4665-4675.
    • (1993) J. Virol. , vol.67 , pp. 4665-4675
    • Hijikata, M.1    Mizushima, H.2    Akagi, T.3    Mori, S.4    Kakiuchi, N.5    Kato, N.6    Tanaka, T.7    Kimura, K.8    Shimotohno, K.9
  • 34
    • 0033573028 scopus 로고    scopus 로고
    • 2+-dependent protease activity and a novel mode of enzyme activation
    • 2+-dependent protease activity and a novel mode of enzyme activation. EMBO J. 18:6880-6889.
    • (1999) EMBO J. , vol.18 , pp. 6880-6889
    • Hosfield, C.M.1    Elce, J.S.2    Davies, P.L.3    Jia, Z.4
  • 36
    • 0031579246 scopus 로고    scopus 로고
    • Hepatitis C virus NS5B protein is a membrane-associated phosphoprotein with a predominantly perinuclear localization
    • Hwang, S. B., K. J. Park, Y. S. Kim, Y. C. Sung, and M. M. Lai. 1997. Hepatitis C virus NS5B protein is a membrane-associated phosphoprotein with a predominantly perinuclear localization. Virology 227:439-446.
    • (1997) Virology , vol.227 , pp. 439-446
    • Hwang, S.B.1    Park, K.J.2    Kim, Y.S.3    Sung, Y.C.4    Lai, M.M.5
  • 37
    • 0032489233 scopus 로고    scopus 로고
    • Complex formation of NS5B with NS3 and NS4A proteins of hepatitis C virus
    • Ishido, S., T. Fujita, and H. Hotta. 1998. Complex formation of NS5B with NS3 and NS4A proteins of hepatitis C virus. Biochem. Biophys. Res. Commun. 244:35-40.
    • (1998) Biochem. Biophys. Res. Commun. , vol.244 , pp. 35-40
    • Ishido, S.1    Fujita, T.2    Hotta, H.3
  • 38
    • 0032898362 scopus 로고    scopus 로고
    • Expression of hepatitis C virus NS5B protein: Characterization of its RNA polymerase activity and RNA binding
    • Ishii, K., Y. Tanaka, C. C. Yap, H. Aizaki, Y. Matsuura, and T. Miyamura. 1999. Expression of hepatitis C virus NS5B protein: characterization of its RNA polymerase activity and RNA binding. Hepatology 29:1227-1235.
    • (1999) Hepatology. , vol.29 , pp. 1227-1235
    • Ishii, K.1    Tanaka, Y.2    Yap, C.C.3    Aizaki, H.4    Matsuura, Y.5    Miyamura, T.6
  • 39
    • 0028983898 scopus 로고
    • Crystal structure of a conserved protease that binds DNA: The bleomycin hydrolase, Gal6
    • Joshua-Tor, L., H. E. Xu, S. A. Johnston, and D. C. Rees. 1995. Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science 269:945-950.
    • (1995) Science , vol.269 , pp. 945-950
    • Joshua-Tor, L.1    Xu, H.E.2    Johnston, S.A.3    Rees, D.C.4
  • 41
    • 0034749457 scopus 로고    scopus 로고
    • Mutations that affect dimer formation and helicase activity of the hepatitis C virus helicase
    • Khu, Y. L., E. Koh, S. P. Lim, Y. H. Tan, S. Brenner, S. G. Lim, W. J. Hong, and P. Y. Goh. 2001. Mutations that affect dimer formation and helicase activity of the hepatitis C virus helicase. J. Virol. 75:205-214.
    • (2001) J. Virol. , vol.75 , pp. 205-214
    • Khu, Y.L.1    Koh, E.2    Lim, S.P.3    Tan, Y.H.4    Brenner, S.5    Lim, S.G.6    Hong, W.J.7    Goh, P.Y.8
  • 42
    • 0037373385 scopus 로고    scopus 로고
    • Analysis of the subcellular localization of hepatitis C virus E2 glycoprotein in live cells using EGFP fusion proteins
    • Kien, F., J. D. Abraham, C. Schuster, and M. P. Kieny. 2003. Analysis of the subcellular localization of hepatitis C virus E2 glycoprotein in live cells using EGFP fusion proteins. J. Gen. Virol. 84:561-566.
    • (2003) J. Gen. Virol. , vol.84 , pp. 561-566
    • Kien, F.1    Abraham, J.D.2    Schuster, C.3    Kieny, M.P.4
  • 43
    • 0028817781 scopus 로고
    • C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity
    • Kim, D. W., Y. Gwack, J. H. Han, and J. Choe. 1995. C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity. Biochem. Biophys. Res. Commun. 215:160-166.
    • (1995) Biochem. Biophys. Res. Commun. , vol.215 , pp. 160-166
    • Kim, D.W.1    Gwack, Y.2    Han, J.H.3    Choe, J.4
  • 45
    • 0032837572 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus NS5A hyperphosphorylation by nonstructural proteins NS3, NS4A, and NS4B
    • Koch, J. O., and R. Bartenschlager. 1999. Modulation of hepatitis C virus NS5A hyperphosphorylation by nonstructural proteins NS3, NS4A, and NS4B. J. Virol. 73:7138-7146.
    • (1999) J. Virol. , vol.73 , pp. 7138-7146
    • Koch, J.O.1    Bartenschlager, R.2
  • 47
    • 0033920304 scopus 로고    scopus 로고
    • Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3′ nontranslated region are essential for virus replication in vivo
    • Kolykhalov, A. A., K. Mihalik, S. M. Feinstone, and C. M. Rice. 2000. Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3′ nontranslated region are essential for virus replication in vivo. J. Virol. 74:2046-2051.
    • (2000) J. Virol. , vol.74 , pp. 2046-2051
    • Kolykhalov, A.A.1    Mihalik, K.2    Feinstone, S.M.3    Rice, C.M.4
  • 48
    • 0032876683 scopus 로고    scopus 로고
    • Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site
    • Lesburg, C. A., M. B. Cable, E. Ferrari, Z. Hong, A. F. Mannarino, and P. C. Weber. 1999. Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site. Nat. Struct. Biol. 6:937-943.
    • (1999) Nat. Struct. Biol. , vol.6 , pp. 937-943
    • Lesburg, C.A.1    Cable, M.B.2    Ferrari, E.3    Hong, Z.4    Mannarino, A.F.5    Weber, P.C.6
  • 49
    • 0028290389 scopus 로고
    • Processing in the hepatitis C virus E2-NS2 region: Identification of p7 and two distinct E2-specific products with different C termini
    • Lin, C., B. D. Lindenbach, B. M. Pragai, D. W. McCourt, and C. M. Rice. 1994. Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini. J. Virol. 68:5063-5073.
    • (1994) J. Virol. , vol.68 , pp. 5063-5073
    • Lin, C.1    Lindenbach, B.D.2    Pragai, B.M.3    McCourt, D.W.4    Rice, C.M.5
  • 50
    • 0029074519 scopus 로고
    • A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro
    • Lin, C., J. A. Thomson, and C. M. Rice. 1995. A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro. J. Virol. 69:4373-4380.
    • (1995) J. Virol. , vol.69 , pp. 4373-4380
    • Lin, C.1    Thomson, J.A.2    Rice, C.M.3
  • 51
    • 0030860853 scopus 로고    scopus 로고
    • The hepatitis C virus NS4A protein: Interactions with the NS4B and NS5A proteins
    • Lin, C., J. W. Wu, K. Hsiao, and M. S. Su. 1997. The hepatitis C virus NS4A protein: interactions with the NS4B and NS5A proteins. J. Virol. 71:6465-6471.
    • (1997) J. Virol. , vol.71 , pp. 6465-6471
    • Lin, C.1    Wu, J.W.2    Hsiao, K.3    Su, M.S.4
  • 53
    • 1842289764 scopus 로고    scopus 로고
    • Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity
    • Lohmann, V., F. Korner, U. Herlan, and R. Bartenschlager. 1997. Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity. J. Virol. 71:8416-8428.
    • (1997) J. Virol. , vol.71 , pp. 8416-8428
    • Lohmann, V.1    Korner, F.2    Herlan, U.3    Bartenschlager, R.4
  • 56
    • 0025249362 scopus 로고
    • Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups
    • Miller, R. H., and R. H. Purcell. 1990. Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups. Proc. Natl. Acad. Sci. USA 87:2057-2061.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 2057-2061
    • Miller, R.H.1    Purcell, R.H.2
  • 58
    • 0019966544 scopus 로고
    • Growth of human hepatoma cells lines with differentiated functions in chemically defined medium
    • Nakahayashi, H., K. Taketa, K. Miyano, T. Yamane, and J. Sato. 1982. Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer Res. 42:3858-3863.
    • (1982) Cancer Res. , vol.42 , pp. 3858-3863
    • Nakahayashi, H.1    Taketa, K.2    Miyano, K.3    Yamane, T.4    Sato, J.5
  • 59
    • 0032710924 scopus 로고    scopus 로고
    • Hyperphosphorylation of the hepatitis C virus NS5A protein requires an active NS3 protease, NS4A, NS4B, and NS5A encoded on the same polyprotein
    • Neddermann, P., A. Clementi, and R. De Francesco. 1999. Hyperphosphorylation of the hepatitis C virus NS5A protein requires an active NS3 protease, NS4A, NS4B, and NS5A encoded on the same polyprotein. J. Virol. 73:9984-9991.
    • (1999) J. Virol. , vol.73 , pp. 9984-9991
    • Neddermann, P.1    Clementi, A.2    De Francesco, R.3
  • 61
    • 0036500976 scopus 로고    scopus 로고
    • The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding
    • Pang, P. S., E. Jankowsky, P. J. Planet, and A. M. Pyle. 2002. The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding. EMBO J. 21:1168-1176.
    • (2002) EMBO J. , vol.21 , pp. 1168-1176
    • Pang, P.S.1    Jankowsky, E.2    Planet, P.J.3    Pyle, A.M.4
  • 62
    • 0032885602 scopus 로고    scopus 로고
    • The non-structural 5A protein of hepatitis C virus
    • Pawlotsky, J. M., and G. Germanidis. 1999. The non-structural 5A protein of hepatitis C virus. J. Viral Hepat. 6:343-356.
    • (1999) J. Viral Hepat. , vol.6 , pp. 343-356
    • Pawlotsky, J.M.1    Germanidis, G.2
  • 63
    • 0347457077 scopus 로고    scopus 로고
    • Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein
    • Piccininni, S., A. Varaklioti, M. Nardelli, B. Dave, K. D. Raney, and J. E. McCarthy. 2002. Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein. J. Biol. Chem. 277:45670-45679.
    • (2002) J. Biol. Chem. , vol.277 , pp. 45670-45679
    • Piccininni, S.1    Varaklioti, A.2    Nardelli, M.3    Dave, B.4    Raney, K.D.5    McCarthy, J.E.6
  • 65
    • 0037127306 scopus 로고    scopus 로고
    • Oligomeric interaction of hepatitis C virus NS5B is critical for catalytic activity of RNA-dependent RNA polymerase
    • Qin, W., H. Luo, T. Nomura, N. Hayashi, T. Yamashita, and S. Murakami. 2002. Oligomeric interaction of hepatitis C virus NS5B is critical for catalytic activity of RNA-dependent RNA polymerase. J. Biol. Chem. 277:2132-2137.
    • (2002) J. Biol. Chem. , vol.277 , pp. 2132-2137
    • Qin, W.1    Luo, H.2    Nomura, T.3    Hayashi, N.4    Yamashita, T.5    Murakami, S.6
  • 66
    • 0029059334 scopus 로고
    • Hepatitis C virus-encoded NS2-3 protease: Cleavage-site mutagenesis and requirements for bimolecular cleavage
    • Reed, K. E., A. Grakoui, and C. M. Rice. 1995. Hepatitis C virus-encoded NS2-3 protease: cleavage-site mutagenesis and requirements for bimolecular cleavage. J. Virol. 69:4127-4136.
    • (1995) J. Virol. , vol.69 , pp. 4127-4136
    • Reed, K.E.1    Grakoui, A.2    Rice, C.M.3
  • 67
    • 0033600812 scopus 로고    scopus 로고
    • Identification of the major phosphorylation site of the hepatitis C virus H strain NS5A protein as serine 2321
    • Reed, K. E., and C. M. Rice. 1999. Identification of the major phosphorylation site of the hepatitis C virus H strain NS5A protein as serine 2321. J. Biol. Chem. 274:28011-28018.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28011-28018
    • Reed, K.E.1    Rice, C.M.2
  • 68
    • 0033992516 scopus 로고    scopus 로고
    • Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties
    • Reed, K. E., and C. M. Rice. 2000. Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties. Curr. Top. Microbiol. Immunol. 242:55-84.
    • (2000) Curr. Top. Microbiol. Immunol. , vol.242 , pp. 55-84
    • Reed, K.E.1    Rice, C.M.2
  • 69
    • 0030828466 scopus 로고    scopus 로고
    • Phosphorylation of the hepatitis C virus NS5A protein in vitro and in vivo: Properties of the NS5A-associated kinase
    • Reed, K. E., J. Xu, and C. M. Rice. 1997. Phosphorylation of the hepatitis C virus NS5A protein in vitro and in vivo: properties of the NS5A-associated kinase. J. Virol. 71:7187-7197.
    • (1997) J. Virol. , vol.71 , pp. 7187-7197
    • Reed, K.E.1    Xu, J.2    Rice, C.M.3
  • 70
    • 0020501764 scopus 로고
    • Monoclonal antibodies which recognize native and denatured forms of the adenovirus DNA-binding protein
    • Reich, N. C., P. Sarnow, E. Duprey, and A. J. Levine. 1983. Monoclonal antibodies which recognize native and denatured forms of the adenovirus DNA-binding protein. Virology 128:480-484.
    • (1983) Virology , vol.128 , pp. 480-484
    • Reich, N.C.1    Sarnow, P.2    Duprey, E.3    Levine, A.J.4
  • 72
    • 0028233530 scopus 로고
    • Biosynthesis and biochemical properties of the hepatitis C virus core protein
    • Santolini, E., G. Migliaccio, and N. La Monica. 1994. Biosynthesis and biochemical properties of the hepatitis C virus core protein. J. Virol. 68:3631-3641.
    • (1994) J. Virol. , vol.68 , pp. 3631-3641
    • Santolini, E.1    Migliaccio, G.2    La Monica, N.3
  • 73
    • 0028832632 scopus 로고
    • The NS2 protein of hepatitis C virus is a transmembrane polypeptide
    • Santolini, E., L. Pacini, C. Fipaldini, G. Migliaccio, and N. Monica. 1995. The NS2 protein of hepatitis C virus is a transmembrane polypeptide. J. Virol. 69:7461-7471.
    • (1995) J. Virol. , vol.69 , pp. 7461-7471
    • Santolini, E.1    Pacini, L.2    Fipaldini, C.3    Migliaccio, G.4    Monica, N.5
  • 74
    • 0035941344 scopus 로고    scopus 로고
    • Determinants for membrane association of the hepatitis C virus RNA-dependent RNA polymerase
    • Schmidt-Mende, J., E. Bieck, T. Hugle, F. Penin, C. M. Rice, H. E. Blum, and D. Moradpour. 2001. Determinants for membrane association of the hepatitis C virus RNA-dependent RNA polymerase. J. Biol. Chem. 276:44052-44063.
    • (2001) J. Biol. Chem. , vol.276 , pp. 44052-44063
    • Schmidt-Mende, J.1    Bieck, E.2    Hugle, T.3    Penin, F.4    Rice, C.M.5    Blum, H.E.6    Moradpour, D.7
  • 75
    • 0037192863 scopus 로고    scopus 로고
    • Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity
    • Shirota, Y., H. Luo, W. Qin, S. Kaneko, T. Yamashita, K. Kobayashi, and S. Murakami. 2002. Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity. J. Biol. Chem. 277:11149-11155.
    • (2002) J. Biol. Chem. , vol.277 , pp. 11149-11155
    • Shirota, Y.1    Luo, H.2    Qin, W.3    Kaneko, S.4    Yamashita, T.5    Kobayashi, K.6    Murakami, S.7
  • 76
    • 0028218513 scopus 로고
    • Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions
    • Simmonds, P., D. B. Smith, F. McOmish, P. L. Yap, J. Kolberg, M. S. Urdea, and E. C. Holmes. 1994. Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions. J. Gen. Virol. 75:1053-1061.
    • (1994) J. Gen. Virol. , vol.75 , pp. 1053-1061
    • Simmonds, P.1    Smith, D.B.2    McOmish, F.3    Yap, P.L.4    Kolberg, J.5    Urdea, M.S.6    Holmes, E.C.7
  • 78
    • 0027199917 scopus 로고
    • Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes
    • Suzich, J. A., J. K. Tamura, F. Palmer-Hill, P. Warrener, A. Grakoui, C. M. Rice, S. M. Feinstone, and M. S. Collett. 1993. Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes. J. Virol. 67:6152-6158.
    • (1993) J. Virol. , vol.67 , pp. 6152-6158
    • Suzich, J.A.1    Tamura, J.K.2    Palmer-Hill, F.3    Warrener, P.4    Grakoui, A.5    Rice, C.M.6    Feinstone, S.M.7    Collett, M.S.8
  • 79
    • 0001118596 scopus 로고    scopus 로고
    • Synthesis, assembly, and processing of viral proteins
    • J. M. Coffin, S. H. Hughes, and H. E. Varmus (ed.). Cold Spring Harbor Laboratory Press, Plainview, N.Y.
    • Swanstrom, R., and J. W. Wills. 1997. Synthesis, assembly, and processing of viral proteins, p. 263-334. In J. M. Coffin, S. H. Hughes, and H. E. Varmus (ed.), Retroviruses. Cold Spring Harbor Laboratory Press, Plainview, N.Y.
    • (1997) Retroviruses , pp. 263-334
    • Swanstrom, R.1    Wills, J.W.2
  • 81
    • 0035947270 scopus 로고    scopus 로고
    • How hepatitis C virus counteracts the interferon response: The jury is still out on NS5A
    • Tan, S. L., and M. G. Katze. 2001. How hepatitis C virus counteracts the interferon response: the jury is still out on NS5A. Virology 284:1-12.
    • (2001) Virology , vol.284 , pp. 1-12
    • Tan, S.L.1    Katze, M.G.2
  • 82
    • 0028978937 scopus 로고
    • Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A
    • Tanji, Y., T. Kaneko, S. Satoh, and K. Shimotohno. 1995. Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A. J. Virol. 69:3980-3986.
    • (1995) J. Virol. , vol.69 , pp. 3980-3986
    • Tanji, Y.1    Kaneko, T.2    Satoh, S.3    Shimotohno, K.4
  • 83
    • 0035824669 scopus 로고    scopus 로고
    • In vitro characterization of a purified NS2/3 protease variant of hepatitis C virus
    • Thibeault, D., R. Maurice, L. Pilote, D. Lamarre, and A. Pause. 2001. In vitro characterization of a purified NS2/3 protease variant of hepatitis C virus. J. Biol. Chem. 276:46678-46684.
    • (2001) J. Biol. Chem. , vol.276 , pp. 46678-46684
    • Thibeault, D.1    Maurice, R.2    Pilote, L.3    Lamarre, D.4    Pause, A.5
  • 84
    • 0026513651 scopus 로고
    • Internal ribosome entry site within hepatitis C virus RNA
    • Tsukiyama-Kohara, K., N. Iizuka, M. Kohara, and A. Nomoto. 1992. Internal ribosome entry site within hepatitis C virus RNA. J. Virol. 66:1476-1483.
    • (1992) J. Virol. , vol.66 , pp. 1476-1483
    • Tsukiyama-Kohara, K.1    Iizuka, N.2    Kohara, M.3    Nomoto, A.4
  • 86
    • 0037124073 scopus 로고    scopus 로고
    • Alternate translation occurs within the core coding region of the hepatitis C viral genome
    • Varaklioti, A., N. Vassilaki, U. Georgopoulou, and P. Mavromara. 2002. Alternate translation occurs within the core coding region of the hepatitis C viral genome. J. Biol. Chem. 277:17713-17721.
    • (2002) J. Biol. Chem. , vol.277 , pp. 17713-17721
    • Varaklioti, A.1    Vassilaki, N.2    Georgopoulou, U.3    Mavromara, P.4
  • 87
    • 0030419901 scopus 로고    scopus 로고
    • Proteolytic processing and particle maturation
    • Vogt, V. M. 1996. Proteolytic processing and particle maturation. Curr. Top. Microbiol. Immunol. 214:95-131.
    • (1996) Curr. Top. Microbiol. Immunol. , vol.214 , pp. 95-131
    • Vogt, V.M.1
  • 88
    • 0035050164 scopus 로고    scopus 로고
    • Evidence for a new hepatitis C virus antigen encoded in an overlapping reading frame
    • Walewski, J. L., T. R. Keller, D. D. Stump, and A. D. Branch. 2001. Evidence for a new hepatitis C virus antigen encoded in an overlapping reading frame. RNA. 7:710-721.
    • (2001) RNA , vol.7 , pp. 710-721
    • Walewski, J.L.1    Keller, T.R.2    Stump, D.D.3    Branch, A.D.4
  • 89
    • 0027153210 scopus 로고
    • Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism
    • Wang, C., P. Sarnow, and A. Siddiqui. 1993. Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism. J. Virol. 67:3338-3344.
    • (1993) J. Virol. , vol.67 , pp. 3338-3344
    • Wang, C.1    Sarnow, P.2    Siddiqui, A.3
  • 91
    • 0030846512 scopus 로고    scopus 로고
    • Ultrastructure of Kunjin virus-infected cells: Colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures
    • Westaway, E. G., J. M. Mackenzie, M. T. Kenney, M. K. Jones, and A. A. Khromykh. 1997. Ultrastructure of Kunjin virus-infected cells: colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures. J. Virol. 71:6650-6661.
    • (1997) J. Virol. , vol.71 , pp. 6650-6661
    • Westaway, E.G.1    Mackenzie, J.M.2    Kenney, M.T.3    Jones, M.K.4    Khromykh, A.A.5
  • 92
    • 0242456017 scopus 로고    scopus 로고
    • Subcellular localization, stability, and transcleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines
    • Wolk, B., D. Sansonno, H. G. Krausslich, F. Dammacco, C. M. Rice, H. E. Blum, and D. Moradpour. 2000. Subcellular localization, stability, and transcleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines. J. Virol. 74:2293-2304.
    • (2000) J. Virol. , vol.74 , pp. 2293-2304
    • Wolk, B.1    Sansonno, D.2    Krausslich, H.G.3    Dammacco, F.4    Rice, C.M.5    Blum, H.E.6    Moradpour, D.7
  • 94
    • 0037031947 scopus 로고    scopus 로고
    • Membrane topology of the hepatitis C virus NS2 protein
    • Yamaga, A. K., and J. H. Ou. 2002. Membrane topology of the hepatitis C virus NS2 protein. J. Biol. Chem. 277:33228-33234.
    • (2002) J. Biol. Chem. , vol.277 , pp. 33228-33234
    • Yamaga, A.K.1    Ou, J.H.2
  • 95
    • 0032546963 scopus 로고    scopus 로고
    • RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the Cterminal region
    • Yamashita, T., S. Kaneko, Y. Shirota, W. Qin, T. Nomura, K. Kobayashi, and S. Murakami. 1998. RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the Cterminal region. J. Biol. Chem. 273:15479-15486.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15479-15486
    • Yamashita, T.1    Kaneko, S.2    Shirota, Y.3    Qin, W.4    Nomura, T.5    Kobayashi, K.6    Murakami, S.7


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