Enhanced activity and stability in the presence of organic solvents by increased active site polarity and stabilization of a surface loop in a metalloprotease

Journal of Biochemistry

Volumn 148, Issue 2, 2010, Pages 231-238

  Badoei Dalfard, Arastoo ^a   Khajeh, Khosro ^a   Asghari, S Mohsen ^b   Ranjbar, Bijan ^a   Karbalaei Heidari, Hamid Reza ^c  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b UNIVERSITY OF GUILAN   (Iran)

^c SHIRAZ UNIVERSITY   (Iran)

Author keywords

activity and stability; organic solvent; site directed mutagenesis; zinc metalloprotease

Indexed keywords

2 PROPANOL; METALLOPROTEINASE; METHANOL; N,N DIMETHYLFORMAMIDE; ORGANIC SOLVENT; PROPANOL;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STABILITY; HEAT TOLERANCE; HYDRATION; MUTATION; NONHUMAN;

SALINIVIBRIO;

EID: 77955207297     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvq057     Document Type: Article

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