Thermostable variants constructed via the structure-guided consensus method also show increased stability in salts solutions and homogeneous aqueous-organic media

Protein Engineering, Design and Selection

Volumn 21, Issue 11, 2008, Pages 673-680

  Vazquez Figueroa, E ^a   Yeh, V ^a   Broering, J M ^a,b   Chaparro Riggers, J F ^a,c   Bommarius, A S ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b Stanford University   (United States)

^c PFIZER INC   (United States)

Author keywords

Biotransformation; Cofactors; Consensus sequence; Organic solvent stability; Protein stability

Indexed keywords

AMINES; AMINO ACIDS; CATALYSTS; CONCENTRATION (PROCESS); ENZYMES; GLUCOSE; MELTING POINT; OFFSHORE OIL WELL PRODUCTION; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC SOLVENTS; PROTEINS; RATE CONSTANTS; SALTS; SOLVENTS; SYSTEM STABILITY;

AMINO ACID SEQUENCES; AQUEOUS; AQUEOUS SYSTEMS; BIOTRANSFORMATION; CHAOTROPIC SALTS; COFACTOR REGENERATIONS; COFACTORS; CONSENSUS METHODS; CONSENSUS SEQUENCE; DEACTIVATION RATES; ENZYME STABILITIES; HIGH CONCENTRATIONS; HIGH SALT CONCENTRATIONS; HIGH TEMPERATURES; HOFMEISTER SERIES; IMPROVED STABILITIES; KINETIC STABILITIES; LOW TEMPERATURES; MAJOR FACTORS; MELTING TEMPERATURES; ORGANIC; ORGANIC MEDIAS; PROTEIN STABILITY; REDOX ENZYMES; SALT CONCENTRATIONS; SALT SOLUTIONS; STRONG CORRELATIONS; TEMPERATURE STABILITIES;

THERMODYNAMIC STABILITY;

GLUTAMATE DEHYDROGENASE; ORGANIC SOLVENT; SODIUM CHLORIDE; WATER;

AMINO ACID SEQUENCE; AQUEOUS SOLUTION; ARTICLE; CONSENSUS SEQUENCE; ENZYME STABILITY; KINETICS; MELTING POINT; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN VARIANT; THERMODYNAMICS; THERMOSTABILITY;

ANIMALS; BACILLUS SUBTILIS; CONSENSUS SEQUENCE; ENZYME STABILITY; GLUCOSE 1-DEHYDROGENASE; HOT TEMPERATURE; KINETICS; ORGANIC CHEMICALS; PROTEIN DENATURATION; SALTS; SOLUTIONS; SOLVENTS; TEMPERATURE;

EID: 54249164978     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzn048     Document Type: Article

References (65)

1. Baik,S.H., Ide,T., Yoshida,H., Kagami,O. and Harayama,S. (2003) Appl. Microbiol. Biotechnol., 61, 329-335.
2. Baik,S.H., Michel,F., Aghajari,N., Haser,R. and Harayama,S. (2005) Appl. Environ. Microbiol., 71, 3285-3293.
3. Bommarius,A.S., Schwarm,M. and Drauz,K. (1998) J. Mol. Catal. B Enzymatic, 5, 1-11.
4. Broering,J.M. and Bommarius,A.S. (2005) J. Phys. Chem. B, 109, 20612-20619.
5. Carrea,G. and Riva,S. (2008) Organic Synthesis with Enzymes in Non-Aqueous Media. WILEY-VCH Verlag GmbH & Co, Weinheim, Germany.
6. Chaparro-Riggers,J.F., Rogers,T.A., Vázquez-Figueroa,E. and Bommarius,A.S. (2007) Adv. Synth. Catal., 349, 1521-1531.
7. Constable,D.J.C., et al. (2007) Green Chem., 9, 411-420.
8. Cowan,D.A. (1997) Comp. Biochem. Physiol. A Physiol., 118, 429-438.
9. Davis-Searles,P.R., Saunders,A.J., Erie,D.A., Winzor,D.J. and Pielak,G.J. (2001) Annu. Rev. Biophys. Biomol. Struct., 30, 271-306.
10. De Wildeman,S.M.A., Sonke,T., Schoemaker,H.E. and May,O. (2007) Acc. Chem. Res., 40, 1260-1266.
11. Dordick,J.S. (1989) Enzyme Microb. Technol., 11, 194-211.
12. Eijsink,V.G.H., Bjork,A., Gaseidnes,S., Sirevag,R., Synstad,B., van den Burg,B. and Vriend,G. (2004) J. Biotechnol., 113, 105-120.
13. Eijsink,V.G.H., Gaseidnes,S., Borchert,T.V. and van den Burg,B. (2005) Biomol. Eng., 22, 21-30.
14. Filikov,A.V., Hayes,R.J., Luo,P.Z., Stark,D.M., Chan,C., Kundu,A. and Dahiyat,B.I. (2002) Protein Sci., 11, 1452-1461.
15. Gaseidnes,S., Synstad,B., Jia,X.H., Kjellesvik,H., Vriend,G. and Eijsink,V.G.H. (2003) Protein Eng., 16, 841-846.
16. Ghatorae,A.S., Guerra,M.J., Bell,G. and Halling,P.J. (1994) Biotechnol. Bioeng., 44, 1355-1361.
17. Gómez-Puyou,A., Darszon,A. and Tuena de Gâomez-Puyou,M. (1992) Biomolecules in Organic Solvents. CRC Press, Boca Raton.
18. Griebenow,K. and Klibanov,A.M. (1996) J. Am. Chem. Soc., 118, 11695-11700.
19. Griebenow,K., Vidal,M., Baez,C., Santos,A.M. and Barletta,G. (2001) J. Am. Chem. Soc., 123, 5380-5381.
20. Gupta,M.N., Batra,R., Tyagi,R. and Sharma,A. (1997) Biotechnol. Prog., 13, 284-288.
21. Haki,G.D. and Rakshit,S.K. (2003) Bioresour. Technol., 89, 17-34.
22. Hall,M., Stueckler,C., Kroutil,W., Macheroux,P. and Faber,K. (2007) Angew. Chem. Int. Edit., 46, 3934-3937.
23. Hao,J.J. and Berry,A. (2004) Protein Eng. Des. Sel., 17, 689-697.
24. Hine,J.S. (1962) Physical Organic Chemistry, 2nd edn. McGraw-Hill, New York.
25. Jaenicke,R. and Zavodszky,P. (1990) FEBS Lett., 268, 344-349.
26. Kandimalla,V.B., Tripathi,V.S. and Ju,H.X. (2006) Crit. Rev. Anal. Chem., 36, 73-106.
27. Khmelnitsky,Y.L., Mozhaev,V.V., Belova,A.B., Sergeeva,M.V. and Martinek,K. (1991) Eur. J. Biochem., 198, 31-41.
28. Khmelnitsky,Y.L., Welch,S.H., Clark,D.S. and Dordick,J.S. (1994) J. Am. Chem. Soc., 116, 2647-2648.
29. Kim,J., Clark,D.S. and Dordick,J.S. (2000) Biotechnol. Bioeng., 67, 112-116.
30. Kim,J., Grate,J.W. and Wang,P. (2006) Chem. Eng. Sci., 61, 1017-1026.
31. Klibanov,A.M., Semenov,A.N., Samokhin,G.P. and Martinek,K. (1978) Bioorg. Khim., 4, 82-87.
32. Korkegian,A., Black,M.E., Baker,D. and Stoddard,B.L. (2005) Science, 308, 857-860.
33. Kumar,S. and Nussinov,R. (2001) Cell Mol. Life Sci., 58, 1216-1233.
34. Laane,C. (1987) Biocatalysis, 1, 17-22.
35. Laane,C., Boeren,S., Vos,K. and Veeger,C. (1986) Biotechnol. Bioeng., 30, 81-87.
36. Lehmann,M. and Wyss,M. (2001) Curr. Opin. Biotechnol., 12, 371-375.
37. Lehmann,M., Loch,C., Middendorf,A., Studer,D., Lassen,S.F., Pasamontes,L., van Loon,A. and Wyss,M. (2002) Protein Eng., 15, 403-411.
38. Mansfeld,J., Vriend,G., Dijkstra,B.W., Veltman,O.R., VandenBurg,B., Venema,G., UlbrichHofmann,R. and Eijsink,V.G.H. (1997) J. Biol. Chem., 272, 11152-11156.
39. Martinek,K., Klibanov,A.M., Samokhin,G.P., Semenov,A.N. and Berezin,I.V. (1977) Bioorg. Khim., 3, 696-702.
40. Martinek,K., Semenov,A.N. and Berezin,I.V. (1980) Dok. Akad. Nauk. SSSR, 254, 121-123.
41. Matthews,B.W., Nicholson,H. and Becktel,W.J. (1987) Proc. Natl Acad. Sci. USA, 84, 6663-6667.
42. Mihovilovic,M.D. (2006) Curr. Org. Chem., 10, 1265-1287.
43. Moore,J.C., Pollard,D.J., Kosjek,B. and Devine,P.N. (2007) Acc. Chem. Res., 40, 1412-1419.
44. Mozhaev,V.V., Khmelnitsky,Y.L., Sergeeva,M.V., Belova,A.B., Klyachko,N.L., Levashov,A.V. and Martinek,K. (1989) Eur. J. Biochem., 184, 597-602.
45. Nagao,T., Makino,Y., Yamamoto,K., Urabe,I. and Okada,H. (1989) FEBS Lett., 253, 113-116.
46. Owusu,R.K. and Cowan,D.A. (1989) Enzyme Microbiol. Technol., 11, 568-574.
47. Panke,S., Held,M. and Wubbolts,M. (2004) Curr. Opin. Biotechnol., 15, 272-279.
48. Polizzi,K.M., Bommarius,A.S., Broering,J.M. and Chaparro-Riggers,J.F. (2007) Curr. Opin. Chem. Biol., 11, 220-225.
49. Polizzi,K.M., Chaparro-Riggers,J.F., Vázquez-Figueroa,E. and Bommarius,A.S. (2006) Biotechnol. J., 1, 531-536.
50. Pollard,D.J. and Woodley,J.M. (2007) Trends Biotechnol., 25, 66-73.
51. Ran,N.Q., Zhao,L.S., Chen,Z.M. and Tao,J.H. (2008) Green Chem., 10, 361-372.
52. Reetz,M.T., D Carballeira,J. and Vogel,A. (2006) Angew. Chem. Int. Ed., 45, 7745-7751.
53. Semenov,A.N. and Martinek,K. (1980) Bioorg. Khim., 6, 1559-1571.
54. Semenov,A.N., Martinek,K. and Berezin,I.V. (1980) Bioorg. Khim., 6, 600-608.
55. Serdakowski,A.L. and Dordick,J.S. (2008) Trends Biotechnol., 26, 48-54.
56. Smallwood,I.M. (1996) Handbook of Organic Solvent Properties. Arnold, Halsted Press, London, New York.
57. Steipe,B., Schiller,B., Pluckthun,A. and Steinbacher,S. (1994) J. Mol. Biol., 240, 188-192.
58. Strickler,S.S., Gribenko,A.V., Keiffer,T.R., Tomlinson,J., Reihle,T., Loladze,V.V. and Makhatadze,G.I. (2006) Biochemistry, 45, 2761-2766.
59. Valivety,R.H., Halling,P.J. and Macrae,A.R. (1992) Biochim. Biophys. Acta, 1118, 218-222.
60. Valivety,R.H., Halling,P.J., Peilow,A.D. and Macrae,A.R. (1994) Eur. J. Biochem., 222, 461-466.
61. Vazquez-Figueroa,E., Chaparro-Riggers,J. and Bommarius,A.S. (2007) ChemBioChem., 8, 2295-2301.
62. Wong,C.H., Drueckhammer,D.G. and Sweers,H.M. (1985) J. Am. Chem. Soc., 107, 4028-4031.
63. Wong,T.S., Arnold,F.H. and Schwaneberg,U. (2004) Biotechnol. Bioeng., 85, 351-358.
64. Wunderlich,M., Martin,A. and Schmid,F.X. (2005) J. Mol. Biol., 347, 1063-1076.
65. Zavodszky,P., Kardos,J., Svingor,A. and Petsko,G.A. (1998) Proc. Natl Acad. Sci. USA, 95, 7406-7411.