-
1
-
-
0031554925
-
Crytal structure of the beta-glycosidase from the hyperthermophilic archeon Sulfolobus solfataricus: Resilience as a key factor in thermostability
-
Aguilar, C. F., I. Sanderson, M. Moracci, M. Ciaramella, R. Nucci, M. Rossi, and L. H. Pearl. 1997. Crytal structure of the beta-glycosidase from the hyperthermophilic archeon Sulfolobus solfataricus: resilience as a key factor in thermostability. J. Mol. Biol. 271:789-802.
-
(1997)
J. Mol. Biol.
, vol.271
, pp. 789-802
-
-
Aguilar, C.F.1
Sanderson, I.2
Moracci, M.3
Ciaramella, M.4
Nucci, R.5
Rossi, M.6
Pearl, L.H.7
-
2
-
-
0030626451
-
Optimizing industrial enzymes by directed evolution
-
Arnold, F. H., and J. C. Moore. 1997. Optimizing industrial enzymes by directed evolution. Adv. Biochem. Eng. Biotechnol. 58:1-14.
-
(1997)
Adv. Biochem. Eng. Biotechnol.
, vol.58
, pp. 1-14
-
-
Arnold, F.H.1
Moore, J.C.2
-
4
-
-
0029892667
-
Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme
-
Baldwin, E., J. Xu, O. Hajiseyedjavadi, W. A. Baase, and B. W. Matthews. 1996. Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme. J. Mol. Biol. 259:542-559.
-
(1996)
J. Mol. Biol.
, vol.259
, pp. 542-559
-
-
Baldwin, E.1
Xu, J.2
Hajiseyedjavadi, O.3
Baase, W.A.4
Matthews, B.W.5
-
5
-
-
0027980041
-
Molecular characterization of enterobacterial pldA genes encoding outer membrane phospholipase A
-
Brok, R. G., E. Brinkman, R. van Boxtel, A. C. Bekkers, H. M. Verheij, and J. Tommassen. 1994. Molecular characterization of enterobacterial pldA genes encoding outer membrane phospholipase A. J. Bacteriol. 176:861-870.
-
(1994)
J. Bacteriol.
, vol.176
, pp. 861-870
-
-
Brok, R.G.1
Brinkman, E.2
Van Boxtel, R.3
Bekkers, A.C.4
Verheij, H.M.5
Tommassen, J.6
-
6
-
-
85045502002
-
Randomization of genes by PCR mutagenesis
-
Cadwell, R. C., and G. F. Joyce. 1992. Randomization of genes by PCR mutagenesis. PCR Methods Applic. 2:28-33.
-
(1992)
PCR Methods Applic.
, vol.2
, pp. 28-33
-
-
Cadwell, R.C.1
Joyce, G.F.2
-
8
-
-
0027163023
-
Signalling properties of lysophosphatidic acid
-
Durieux, M. E., and K. R. Lynch. 1993. Signalling properties of lysophosphatidic acid. Trends Pharmacol. Sci. 14:249-254.
-
(1993)
Trends Pharmacol. Sci.
, vol.14
, pp. 249-254
-
-
Durieux, M.E.1
Lynch, K.R.2
-
9
-
-
0029548161
-
Engineering surface charges in a subtilisin
-
Egmond, M. R., W. P. Antheunisse, P. Ravestein, A. T. Mooren, and J. de Vlieg. 1996. Engineering surface charges in a subtilisin. Adv. Exp. Med. Biol. 379:219-228.
-
(1996)
Adv. Exp. Med. Biol.
, vol.379
, pp. 219-228
-
-
Egmond, M.R.1
Antheunisse, W.P.2
Ravestein, P.3
Mooren, A.T.4
De Vlieg, J.5
-
10
-
-
0029162070
-
Understanding and increasing protein stability
-
Fagain, C. O. 1995. Understanding and increasing protein stability. Biochim. Biophys. Acta 1252:1-14.
-
(1995)
Biochim. Biophys. Acta
, vol.1252
, pp. 1-14
-
-
Fagain, C.O.1
-
11
-
-
0029919832
-
Design of heterotetrameric coiled coils: Evidence for increased stabilization by Glu(-)-Lys(+) ion pair interactions
-
Fairman, R., H. G. Chao, T. B. Lavoie, J. J. Villafranca, G. R. Matsueda, and J. Novotny. 1996. Design of heterotetrameric coiled coils: evidence for increased stabilization by Glu(-)-Lys(+) ion pair interactions. Biochemistry 35:2824-2829.
-
(1996)
Biochemistry
, vol.35
, pp. 2824-2829
-
-
Fairman, R.1
Chao, H.G.2
Lavoie, T.B.3
Villafranca, J.J.4
Matsueda, G.R.5
Novotny, J.6
-
12
-
-
0032573217
-
Directed evolution of a thermostable esterase
-
Giver, L., A. Gershenson, P. O. Freskgard, and F. H. Arnold. 1998. Directed evolution of a thermostable esterase. Proc. Natl. Acad. Sci. USA 95:12809-12813.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12809-12813
-
-
Giver, L.1
Gershenson, A.2
Freskgard, P.O.3
Arnold, F.H.4
-
13
-
-
0033616712
-
Thermal adaptation analyzed by comparison of protein sequences from mesophilic and extremely thermophilic Methanococcus species
-
Haney, P. J., J. H. Badger, G. L. Buldak, C. I. Reich, C. R. Woese, and G. J. Olsen. 1999. Thermal adaptation analyzed by comparison of protein sequences from mesophilic and extremely thermophilic Methanococcus species. Proc. Natl. Acad. Sci. USA 96:3578-3583.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3578-3583
-
-
Haney, P.J.1
Badger, J.H.2
Buldak, G.L.3
Reich, C.I.4
Woese, C.R.5
Olsen, G.J.6
-
14
-
-
4243067681
-
Protein stabilization by removal of unsatisfied polar groups: Computational approaches and experimental tests
-
Hendsch, Z. S., T. Jonsson, R. T. Sauer, and B. Tidor. 1996. Protein stabilization by removal of unsatisfied polar groups: computational approaches and experimental tests. Biochemistry 35:7621-7625.
-
(1996)
Biochemistry
, vol.35
, pp. 7621-7625
-
-
Hendsch, Z.S.1
Jonsson, T.2
Sauer, R.T.3
Tidor, B.4
-
15
-
-
0028358990
-
Allergens in hymenoptera venom. XXVI. The complete amino acid sequences of two vespid venom phospholipases
-
Hoffman, D. R. 1994. Allergens in hymenoptera venom. XXVI. The complete amino acid sequences of two vespid venom phospholipases. Int. Arch. Allergy Immunol. 104:184-190.
-
(1994)
Int. Arch. Allergy Immunol.
, vol.104
, pp. 184-190
-
-
Hoffman, D.R.1
-
16
-
-
0031042074
-
Ion-pair and charged hydrogen-bond interactions between histidine and aspartate in a peptide helix
-
Huyghues-Despointes, B. M., and R. L. Baldwin. 1997. Ion-pair and charged hydrogen-bond interactions between histidine and aspartate in a peptide helix. Biochemistry 36:1965-1970.
-
(1997)
Biochemistry
, vol.36
, pp. 1965-1970
-
-
Huyghues-Despointes, B.M.1
Baldwin, R.L.2
-
17
-
-
0030067190
-
Stability and folding of ultrastable proteins: Eye lens crystallins and enzymes from thermophiles
-
Jaenicke, R. 1996. Stability and folding of ultrastable proteins: eye lens crystallins and enzymes from thermophiles. FASEB J. 10:84-92.
-
(1996)
FASEB J.
, vol.10
, pp. 84-92
-
-
Jaenicke, R.1
-
18
-
-
0342900944
-
-
April. U.S. patent 5,744,459
-
Makriyannis, A., R. L. Duclos, and D. J. Fournier. April 1998. Phospholipid compounds and use therefor. U.S. patent 5,744,459.
-
(1998)
Phospholipid Compounds and Use Therefor
-
-
Makriyannis, A.1
Duclos, R.L.2
Fournier, D.J.3
-
19
-
-
0023741058
-
Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3
-
Matsumura, M., W. J. Becktel, and B. W. Matthews. 1988. Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3. Nature 334:406-410.
-
(1988)
Nature
, vol.334
, pp. 406-410
-
-
Matsumura, M.1
Becktel, W.J.2
Matthews, B.W.3
-
20
-
-
0031080996
-
A two-dimensional NMR study of exchange behavior of amide hydrogens in a lysozyme derivative with an extra cross-link between Glu35 and Trp108 - Quenching of cooperative fluctuations and effects on the protein stability
-
Noda, Y., Y. Fukuda, and S. Segawa. 1997. A two-dimensional NMR study of exchange behavior of amide hydrogens in a lysozyme derivative with an extra cross-link between Glu35 and Trp108 - quenching of cooperative fluctuations and effects on the protein stability. Biopolymers 41:131-143.
-
(1997)
Biopolymers
, vol.41
, pp. 131-143
-
-
Noda, Y.1
Fukuda, Y.2
Segawa, S.3
-
22
-
-
0023691688
-
The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: Subtilisin as a test case
-
Pantoliano, M. W., M. Whitlow, J. F. Wood, M. L. Rollence, B. C. Finzel, G. L. Gilliland, T. L. Poulos, and P. N. Bryan. 1988. The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case. Biochemistry 27:8311-8317.
-
(1988)
Biochemistry
, vol.27
, pp. 8311-8317
-
-
Pantoliano, M.W.1
Whitlow, M.2
Wood, J.F.3
Rollence, M.L.4
Finzel, B.C.5
Gilliland, G.L.6
Poulos, T.L.7
Bryan, P.N.8
-
24
-
-
0029822284
-
An evaluation of possible mechanisms underlying amiodarone-induced pulmonary toxicity
-
Reasor, M. J., and S. Kacew. 1996. An evaluation of possible mechanisms underlying amiodarone-induced pulmonary toxicity. Proc. Soc. Exp. Biol. Med. 212:297-304.
-
(1996)
Proc. Soc. Exp. Biol. Med.
, vol.212
, pp. 297-304
-
-
Reasor, M.J.1
Kacew, S.2
-
25
-
-
0029554780
-
Disulfide stabilization of antibody Fv: Computer predictions and experimental evaluation
-
Reiter, Y., U. Brinkmann, S. H. Jung, I. Pastan, and B. Lee. 1995. Disulfide stabilization of antibody Fv: computer predictions and experimental evaluation. Protein Eng. 8:1323-1331.
-
(1995)
Protein Eng.
, vol.8
, pp. 1323-1331
-
-
Reiter, Y.1
Brinkmann, U.2
Jung, S.H.3
Pastan, I.4
Lee, B.5
-
26
-
-
0030877138
-
Protein engineering from a bioindustrial point of view
-
Rubingh, D. N. 1997. Protein engineering from a bioindustrial point of view. Curr. Opin. Biotechnol. 8:417-422.
-
(1997)
Curr. Opin. Biotechnol.
, vol.8
, pp. 417-422
-
-
Rubingh, D.N.1
-
27
-
-
0029099960
-
Engineering thermostability: Lessons from thermophilic proteins
-
Russell, R. J., and G. L. Taylor. 1995. Engineering thermostability: lessons from thermophilic proteins. Curr. Opin. Biotechnol. 6:370-374.
-
(1995)
Curr. Opin. Biotechnol.
, vol.6
, pp. 370-374
-
-
Russell, R.J.1
Taylor, G.L.2
-
28
-
-
0004136246
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
(1989)
Molecular Cloning: A Laboratory Manual, 2nd Ed.
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
29
-
-
0031872389
-
Phospholipase A of Yersinia enterocolitica contributes to pathogenesis in a mouse model
-
Schmiel, D. H., E. Wagar, L. Karamanou, D. Weeks, and V. L. Miller. 1998. Phospholipase A of Yersinia enterocolitica contributes to pathogenesis in a mouse model. Infect. Immun. 66:3941-3951.
-
(1998)
Infect. Immun.
, vol.66
, pp. 3941-3951
-
-
Schmiel, D.H.1
Wagar, E.2
Karamanou, L.3
Weeks, D.4
Miller, V.L.5
-
30
-
-
0028896311
-
A relationship between protein stability and protein function
-
Shoichet, B. K., W. A. Baase, R. Kuroki, and B. W. Matthews. 1995. A relationship between protein stability and protein function. Proc. Natl. Acad. Sci. USA 92:452-456.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 452-456
-
-
Shoichet, B.K.1
Baase, W.A.2
Kuroki, R.3
Matthews, B.W.4
-
31
-
-
0025005525
-
Contributions of the large hydrophobic amino acids to the stability of staphylococcal nuclease
-
Shortle, D., W. E. Stites, and A. K. Meeker. 1990. Contributions of the large hydrophobic amino acids to the stability of staphylococcal nuclease. Biochemistry 29:8033-8041.
-
(1990)
Biochemistry
, vol.29
, pp. 8033-8041
-
-
Shortle, D.1
Stites, W.E.2
Meeker, A.K.3
-
33
-
-
0028110130
-
DNA shuffling by random fragmentation and reassembly: In vitro recombination for molecular evolution
-
Stemmer, W. P. 1994. DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution. Proc. Natl. Acad. Sci. USA 91:10747-10751.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10747-10751
-
-
Stemmer, W.P.1
-
34
-
-
0031938211
-
Engineering of a cold-adapted protease by sequential random mutagenesis and a screening system
-
Taguchi, S., A. Ozaki, and H. Momose. 1998. Engineering of a cold-adapted protease by sequential random mutagenesis and a screening system. Appl. Environ. Microbiol. 64:492-495.
-
(1998)
Appl. Environ. Microbiol.
, vol.64
, pp. 492-495
-
-
Taguchi, S.1
Ozaki, A.2
Momose, H.3
-
35
-
-
0029890431
-
Analysis of the critical sites for protein thermostabilization by proline substitution in oligo-1,6-glucosidase from Bacillus coagulans ATCC 7050 and the evolutionary consideration of proline residues
-
Watanabe, K., K. Kitamura, and Y. Suzuki. 1996. Analysis of the critical sites for protein thermostabilization by proline substitution in oligo-1,6-glucosidase from Bacillus coagulans ATCC 7050 and the evolutionary consideration of proline residues. Appl. Environ. Microbiol. 62:2066-2073.
-
(1996)
Appl. Environ. Microbiol.
, vol.62
, pp. 2066-2073
-
-
Watanabe, K.1
Kitamura, K.2
Suzuki, Y.3
-
36
-
-
0032510667
-
Directed evolution of an aspartate aminotransferase with new substrate specificities
-
Yano, T., S. Oue, and H. Kagamiyama. 1998. Directed evolution of an aspartate aminotransferase with new substrate specificities. Proc. Natl. Acad. Sci. USA 95:5511-5515.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5511-5515
-
-
Yano, T.1
Oue, S.2
Kagamiyama, H.3
-
37
-
-
0023368698
-
Dependence of conformational stability on hydrophobicity of the amino acid residue in a series of variant proteins substituted at a unique position of tryptophan synthase alpha subunit
-
Yutani, K., K. Ogasahara, T. Tsujita, and Y. Sugino. 1987. Dependence of conformational stability on hydrophobicity of the amino acid residue in a series of variant proteins substituted at a unique position of tryptophan synthase alpha subunit. Proc. Natl. Acad. Sci. USA 84:4441-4444.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 4441-4444
-
-
Yutani, K.1
Ogasahara, K.2
Tsujita, T.3
Sugino, Y.4
-
38
-
-
0032973026
-
Directed evolution converts subtilisin E into a functional equivalent of thermitase
-
Zhao, H., and F. H. Arnold. 1999. Directed evolution converts subtilisin E into a functional equivalent of thermitase. Protein Eng. 12:47-53.
-
(1999)
Protein Eng.
, vol.12
, pp. 47-53
-
-
Zhao, H.1
Arnold, F.H.2
|