-
1
-
-
0038621384
-
Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death
-
Arlt A, Gehrz A, Muerkoster S, Vorndamm J, Kruse ML, Folsch UR, Schafer H (2003) Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death. Oncogene 22: 3243-3251
-
(2003)
Oncogene
, vol.22
, pp. 3243-3251
-
-
Arlt, A.1
Gehrz, A.2
Muerkoster, S.3
Vorndamm, J.4
Kruse, M.L.5
Folsch, U.R.6
Schafer, H.7
-
2
-
-
0035422178
-
Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells
-
Bachelder RE, Crago A, Chung J, Wendt MA, Shaw LM, Robinson G, Mercurio AM (2001) Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells. Cancer Res 61: 5736-5740
-
(2001)
Cancer Res
, vol.61
, pp. 5736-5740
-
-
Bachelder, R.E.1
Crago, A.2
Chung, J.3
Wendt, M.A.4
Shaw, L.M.5
Robinson, G.6
Mercurio, A.M.7
-
3
-
-
0141816865
-
Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells
-
Bachelder RE, Lipscomb EA, Lin X, Wendt MA, Chadborn NH, Eickholt BJ, Mercurio AM (2003) Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells. Cancer Res 63: 5230-5233
-
(2003)
Cancer Res
, vol.63
, pp. 5230-5233
-
-
Bachelder, R.E.1
Lipscomb, E.A.2
Lin, X.3
Wendt, M.A.4
Chadborn, N.H.5
Eickholt, B.J.6
Mercurio, A.M.7
-
4
-
-
0037386821
-
Combined vascular endothelial growth factor and TP53 status predicts poor response to tamoxifen therapy in estrogen receptor-positive advanced breast cancer
-
Berns EM, Klijn JG, Look MP, Grebenchtchikov N, Vossen R, Peters H, Geurts-Moespot A, Portengen H, Van Staveren IL, Meijer-Van Gelder ME, Bakker B, Sweep FC, Foekens JA (2003) Combined vascular endothelial growth factor and TP53 status predicts poor response to tamoxifen therapy in estrogen receptor-positive advanced breast cancer. Clin Cancer Res 9: 1253-1258
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1253-1258
-
-
Berns, E.M.1
Klijn, J.G.2
Look, M.P.3
Grebenchtchikov, N.4
Vossen, R.5
Peters, H.6
Geurts-Moespot, A.7
Portengen, H.8
Van Staveren, I.L.9
Meijer-Van Gelder, M.E.10
Bakker, B.11
Sweep, F.C.12
Foekens, J.A.13
-
5
-
-
0033870677
-
Comparative pharmacokinetic analysis of 5-fluorouracil and its major metabolite 5-fluoro-5, 6-dihydrouracil after conventional and reduced test dose in cancer patients
-
Bocci G, Danesi R, Di Paolo AD, Innocenti F, Allegrini G, Falcone A, Melosi A, Battistoni M, Barsanti G, Conte PF, Del Tacca M (2000) Comparative pharmacokinetic analysis of 5-fluorouracil and its major metabolite 5-fluoro-5, 6-dihydrouracil after conventional and reduced test dose in cancer patients. Clin Cancer Res 6: 3032-3037
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3032-3037
-
-
Bocci, G.1
Danesi, R.2
Di Paolo, A.D.3
Innocenti, F.4
Allegrini, G.5
Falcone, A.6
Melosi, A.7
Battistoni, M.8
Barsanti, G.9
Conte, P.F.10
Del Tacca, M.11
-
6
-
-
0034618369
-
MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells
-
Boucher MJ, Morisset J, Vachon PH, Reed JC, Laine J, Rivard N (2000) MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells. J Cell Biochem 79: 355-369
-
(2000)
J Cell Biochem
, vol.79
, pp. 355-369
-
-
Boucher, M.J.1
Morisset, J.2
Vachon, P.H.3
Reed, J.C.4
Laine, J.5
Rivard, N.6
-
7
-
-
2342443733
-
JNK regulates HIPK3 expression and promotes resistance to Fas-mediated apoptosis in du 145 prostate carcinoma cells
-
Curtin JF, Cotter TG (2004) JNK regulates HIPK3 expression and promotes resistance to Fas-mediated apoptosis in DU 145 prostate carcinoma cells. J Biol Chem 279: 17090-17100
-
(2004)
J Biol Chem
, vol.279
, pp. 17090-17100
-
-
Curtin, J.F.1
Cotter, T.G.2
-
8
-
-
0033817158
-
Phase I and pharmacologic study of weekly gemcitabine and paclitaxel in chemo-naive patients with advanced non-small-cell lung cancer
-
De Pas T, de Braud F, Danesi R, Sessa C, Catania C, Curigliano G, Fogli S, del Tacca M, Zampino G, Sbanotto A, Rocca A, Cinieri S, Marrocco E, Milani A, Goldhirsch A (2000) Phase I and pharmacologic study of weekly gemcitabine and paclitaxel in chemo-naive patients with advanced non-small-cell lung cancer. Ann Oncol 11: 821-827
-
(2000)
Ann Oncol
, vol.11
, pp. 821-827
-
-
De Pas, T.1
De Braud, F.2
Danesi, R.3
Sessa, C.4
Catania, C.5
Curigliano, G.6
Fogli, S.7
Del Tacca, M.8
Zampino, G.9
Sbanotto, A.10
Rocca, A.11
Cinieri, S.12
Marrocco, E.13
Milani, A.14
Goldhirsch, A.15
-
9
-
-
1642551021
-
Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma ecus
-
Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE (2004) Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma ecus. Clin Cancer Res 10: 2307-2318
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2307-2318
-
-
Duxbury, M.S.1
Ito, H.2
Zinner, M.J.3
Ashley, S.W.4
Whang, E.E.5
-
10
-
-
0029004025
-
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
Dvorak HF, Brown LF, Detmar M, Dvorak AM (1995) Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 146: 1029-1039
-
(1995)
Am J Pathol
, vol.146
, pp. 1029-1039
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
Dvorak, A.M.4
-
11
-
-
0035990106
-
Gemcitabine, epirubicin and paclitaxel: Pharmacokinetic and pharmacodynamic interactions in advanced breast cancer
-
Fogli S, Danesi R, Gennari A, Donati S, Conte PF, Del Tacca M (2002) Gemcitabine, epirubicin and paclitaxel: pharmacokinetic and pharmacodynamic interactions in advanced breast cancer. Ann Oncol 13: 919-927
-
(2002)
Ann Oncol
, vol.13
, pp. 919-927
-
-
Fogli, S.1
Danesi, R.2
Gennari, A.3
Donati, S.4
Conte, P.F.5
Del Tacca, M.6
-
12
-
-
0028057613
-
Disruption of epithelial cell-matrix interactions induces apoptosis
-
Frisch SM, Francis H (1994) Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124: 619-626
-
(1994)
J Cell Biol
, vol.124
, pp. 619-626
-
-
Frisch, S.M.1
Francis, H.2
-
13
-
-
0034282885
-
The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1
-
Fuh G, Garcia KC, de Vos AM (2000) The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1. J Biol Chem 275: 26690-26695
-
(2000)
J Biol Chem
, vol.275
, pp. 26690-26695
-
-
Fuh, G.1
Garcia, K.C.2
De Vos, A.M.3
-
14
-
-
0032146088
-
Expression of two angiogenic factors, vascular endothelial growth factor and platelet-derived endothelial cell growth factor in human pancreatic cancer, and its relationship to angiogenesis
-
Fujimoto K, Hosotani R, Wada M, Lee JU, Koshiba T, Miyamoto Y, Tsuji S, Nakajima S, Doi R, Imamura M (1998) Expression of two angiogenic factors, vascular endothelial growth factor and platelet-derived endothelial cell growth factor in human pancreatic cancer, and its relationship to angiogenesis. Eur J Cancer 34: 1439-1447
-
(1998)
Eur J Cancer
, vol.34
, pp. 1439-1447
-
-
Fujimoto, K.1
Hosotani, R.2
Wada, M.3
Lee, J.U.4
Koshiba, T.5
Miyamoto, Y.6
Tsuji, S.7
Nakajima, S.8
Doi, R.9
Imamura, M.10
-
15
-
-
0842268386
-
Aberrant expression of neuropilin-1 and -2 in human pancreatic cancer cells
-
Fukahi K, Fukasawa M, Neufeld G, Itakura J, Korc M (2004) Aberrant expression of neuropilin-1 and -2 in human pancreatic cancer cells. Clin Cancer Res 10: 581-590
-
(2004)
Clin Cancer Res
, vol.10
, pp. 581-590
-
-
Fukahi, K.1
Fukasawa, M.2
Neufeld, G.3
Itakura, J.4
Korc, M.5
-
16
-
-
0012366019
-
Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway
-
Fukazawa H, Noguchi K, Murakami Y, Uehara Y (2002) Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway. Mol Cancer Ther 1: 303-309
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 303-309
-
-
Fukazawa, H.1
Noguchi, K.2
Murakami, Y.3
Uehara, Y.4
-
17
-
-
0141721698
-
Differential expression of vascular endothelial growth factor-A isoforms at different stages of melanoma progression
-
Gorski DH, Leal AD, Goydos JS (2003) Differential expression of vascular endothelial growth factor-A isoforms at different stages of melanoma progression. J Am Coll Surg 197: 408-418
-
(2003)
J Am Coll Surg
, vol.197
, pp. 408-418
-
-
Gorski, D.H.1
Leal, A.D.2
Goydos, J.S.3
-
18
-
-
1442329388
-
Expression of neuropilin-1 in high-grade dysplasia, invasive cancer, and metastases of the human gastrointestinal tract
-
Hansel DE, Wilentz RE, Yeo CJ, Schulick RD, Montgomery E, Maitra A (2004) Expression of neuropilin-1 in high-grade dysplasia, invasive cancer, and metastases of the human gastrointestinal tract. Am J Surg Pathol 28: 347-356
-
(2004)
Am J Surg Pathol
, vol.28
, pp. 347-356
-
-
Hansel, D.E.1
Wilentz, R.E.2
Yeo, C.J.3
Schulick, R.D.4
Montgomery, E.5
Maitra, A.6
-
19
-
-
0033991167
-
Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer
-
Itakura J, Ishiwata T, Shen B, Kornmann M, Korc M (2000) Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer. Int J Cancer 85: 27-34
-
(2000)
Int J Cancer
, vol.85
, pp. 27-34
-
-
Itakura, J.1
Ishiwata, T.2
Shen, B.3
Kornmann, M.4
Korc, M.5
-
20
-
-
0033215389
-
Extracellular signal-regulated kinase activation is required for up-regulation of vascular endothelial growth factor by serum starvation in human colon carcinoma cells
-
Jung YD, Nakano K, Liu W, Gallick GE, Ellis LM (1999) Extracellular signal-regulated kinase activation is required for up-regulation of vascular endothelial growth factor by serum starvation in human colon carcinoma cells. Cancer Res 59: 4804-4807
-
(1999)
Cancer Res
, vol.59
, pp. 4804-4807
-
-
Jung, Y.D.1
Nakano, K.2
Liu, W.3
Gallick, G.E.4
Ellis, L.M.5
-
21
-
-
0034075041
-
Prognostic value of vascular endothelial growth factor expression in colorectal cancer patients
-
Lee J, Chow N, Want S, Huan S (2000) Prognostic value of vascular endothelial growth factor expression in colorectal cancer patients. Eur J Cancer 36: 748-753
-
(2000)
Eur J Cancer
, vol.36
, pp. 748-753
-
-
Lee, J.1
Chow, N.2
Want, S.3
Huan, S.4
-
22
-
-
0035885932
-
Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors
-
Masood R, Cai J, Zheng T, Smith DL, Hinton DR, Gill PS (2001) Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors. Blood 98: 1904-1913
-
(2001)
Blood
, vol.98
, pp. 1904-1913
-
-
Masood, R.1
Cai, J.2
Zheng, T.3
Smith, D.L.4
Hinton, D.R.5
Gill, P.S.6
-
23
-
-
0033674846
-
Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression
-
Miao HQ, Lee P, Lin H, Soker S, Klagsbrun M (2000) Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression. FASEB J 14: 2532-2539
-
(2000)
FASEB J
, vol.14
, pp. 2532-2539
-
-
Miao, H.Q.1
Lee, P.2
Lin, H.3
Soker, S.4
Klagsbrun, M.5
-
24
-
-
0042071578
-
Expression and regulation of the novel vascular endothelial growth factor receptor neuropilin-1 by epidermal growth factor in human pancreatic carcinoma
-
Parikh AA, Liu WB, Fan F, Stoeltzing O, Reinmuth N, Bruns CJ, Bucana CD, Evans DB, Ellis LM (2003) Expression and regulation of the novel vascular endothelial growth factor receptor neuropilin-1 by epidermal growth factor in human pancreatic carcinoma. Cancer 98: 720-729
-
(2003)
Cancer
, vol.98
, pp. 720-729
-
-
Parikh, A.A.1
Liu, W.B.2
Fan, F.3
Stoeltzing, O.4
Reinmuth, N.5
Bruns, C.J.6
Bucana, C.D.7
Evans, D.B.8
Ellis, L.M.9
-
25
-
-
0036057585
-
Acquired resistance of pancreatic cancer cells towards 5-Fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes
-
Shi X, Liu S, Kleeff J, Friess H, Buchler MW (2002) Acquired resistance of pancreatic cancer cells towards 5-Fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes. Oncology 62: 354-362
-
(2002)
Oncology
, vol.62
, pp. 354-362
-
-
Shi, X.1
Liu, S.2
Kleeff, J.3
Friess, H.4
Buchler, M.W.5
-
26
-
-
0032549799
-
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
-
Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M (1998) Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92: 735-745
-
(1998)
Cell
, vol.92
, pp. 735-745
-
-
Soker, S.1
Takashima, S.2
Miao, H.Q.3
Neufeld, G.4
Klagsbrun, M.5
-
27
-
-
2442606429
-
Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility
-
Subauste MC, Pertz O, Adamson ED, Turner CE, Junger S, Hahn KM (2004) Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility. J Cell Biol 165: 371-381
-
(2004)
J Cell Biol
, vol.165
, pp. 371-381
-
-
Subauste, M.C.1
Pertz, O.2
Adamson, E.D.3
Turner, C.E.4
Junger, S.5
Hahn, K.M.6
-
28
-
-
0041592695
-
Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer
-
Swan EA, Jasser SA, Holsinger FC, Doan D, Bucana C, Myers JN (2003) Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer. Oral Oncol 39: 648-655
-
(2003)
Oral Oncol
, vol.39
, pp. 648-655
-
-
Swan, E.A.1
Jasser, S.A.2
Holsinger, F.C.3
Doan, D.4
Bucana, C.5
Myers, J.N.6
-
29
-
-
0033214312
-
Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors
-
Takahashi T, Fournier A, Nakamura F, Wang LH, Murakami Y, Kalb RG, Fujisawa H, Strittmatter SM (1999) Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell 99: 59-69
-
(1999)
Cell
, vol.99
, pp. 59-69
-
-
Takahashi, T.1
Fournier, A.2
Nakamura, F.3
Wang, L.H.4
Murakami, Y.5
Kalb, R.G.6
Fujisawa, H.7
Strittmatter, S.M.8
-
30
-
-
84970070220
-
Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
-
Takahashi Y, Kitadai Y, Bucana CD, Cleary KR, Ellis LM (1995) Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 55: 3964-3968
-
(1995)
Cancer Res
, vol.55
, pp. 3964-3968
-
-
Takahashi, Y.1
Kitadai, Y.2
Bucana, C.D.3
Cleary, K.R.4
Ellis, L.M.5
-
31
-
-
0025023532
-
Heterogeneity of potential for hematogenous metastasis in a human pancreatic carcinoma
-
Vezeridis MP, Meitner PA, Tibbetts LM, Doremus CM, Tzanakakis G, Calabresi P (1990) Heterogeneity of potential for hematogenous metastasis in a human pancreatic carcinoma. J Surg Res 48: 51-55
-
(1990)
J Surg Res
, vol.48
, pp. 51-55
-
-
Vezeridis, M.P.1
Meitner, P.A.2
Tibbetts, L.M.3
Doremus, C.M.4
Tzanakakis, G.5
Calabresi, P.6
-
32
-
-
1542571789
-
Neuropilin-1-mediated vascular permeability factor/vascular endothelial growth factor-dependent endothelial cell migration
-
Wang L, Zeng H, Wang P, Soker S, Mukhopadhyay D (2003) Neuropilin-1-mediated vascular permeability factor/vascular endothelial growth factor-dependent endothelial cell migration. J Biol Chem 278: 48848-48860
-
(2003)
J Biol Chem
, vol.278
, pp. 48848-48860
-
-
Wang, L.1
Zeng, H.2
Wang, P.3
Soker, S.4
Mukhopadhyay, D.5
-
33
-
-
0035816698
-
Vascular endothelial growth factor receptor-2 and neuropilin-1 form a receptor complex that is responsible for the differential signaling potency of VEGF(165) and VEGF(121)
-
Whitaker GB, Limberg BJ, Rosenbaum JS (2001) Vascular endothelial growth factor receptor-2 and neuropilin-1 form a receptor complex that is responsible for the differential signaling potency of VEGF(165) and VEGF(121). J Biol Chem 276: 25520-25531
-
(2001)
J Biol Chem
, vol.276
, pp. 25520-25531
-
-
Whitaker, G.B.1
Limberg, B.J.2
Rosenbaum, J.S.3
-
34
-
-
0037237136
-
C-Jun NH(2)-terminal kinase mediates proliferation and tumor growth of human prostate carcinoma
-
Yang YM, Bost F, Charbono W, Dean N, McKay R, Rhim JS, Depatie C, Mercola D (2003) C-Jun NH(2)-terminal kinase mediates proliferation and tumor growth of human prostate carcinoma. Clin Cancer Res 9: 391-401
-
(2003)
Clin Cancer Res
, vol.9
, pp. 391-401
-
-
Yang, Y.M.1
Bost, F.2
Charbono, W.3
Dean, N.4
McKay, R.5
Rhim, J.S.6
Depatie, C.7
Mercola, D.8
-
35
-
-
1242316958
-
JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD
-
Yu C, Minemoto Y, Zhang J, Liu J, Tang F, Bui TN, Xiang J, Lin A (2004) JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD. Mol Cell 13: 329-340
-
(2004)
Mol Cell
, vol.13
, pp. 329-340
-
-
Yu, C.1
Minemoto, Y.2
Zhang, J.3
Liu, J.4
Tang, F.5
Bui, T.N.6
Xiang, J.7
Lin, A.8
|