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Volumn 11, Issue 7, 2010, Pages 2715-2745

Nitric oxide: Perspectives and emerging studies of a well known cytotoxin

Author keywords

Cytotoxicity; Epigenetics; High NO adaptation; Nitric oxide; Oncogenetic

Indexed keywords

ANDROGEN RECEPTOR; ANTINEOPLASTIC AGENT; APC PROTEIN; BRCA1 PROTEIN; CISPLATIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLOOXYGENASE 2; CYTOTOXIN; DEATH ASSOCIATED PROTEIN KINASE; DICKKOPF 1 PROTEIN; DNA; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESTROGEN RECEPTOR; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE P1; HISTONE; INDUCIBLE NITRIC OXIDE SYNTHASE; MICRORNA; NITRIC OXIDE; ORAL CONTRACEPTIVE AGENT; PROTEIN MLH1; REACTIVE NITROGEN SPECIES; SOMATOMEDIN BINDING PROTEIN 3; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 5; TRANSCRIPTION FACTOR HOXA9; UVOMORULIN;

EID: 77955067714     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms11072715     Document Type: Review
Times cited : (46)

References (190)
  • 1
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott, R.F.; Zawadzki, J.V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980, 288, 373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 2
    • 0001509578 scopus 로고
    • Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to escherichia coli lipopolysaccharide
    • USA
    • Stuehr, D.J.; Marletta, M.A. Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to escherichia coli lipopolysaccharide. Proc. Natl. Acad. Sci. USA 1985, 82, 7738-7742.
    • (1985) Proc. Natl. Acad. Sci , vol.82 , pp. 7738-7742
    • Stuehr, D.J.1    Marletta, M.A.2
  • 3
    • 0031401213 scopus 로고    scopus 로고
    • Nitric oxide signaling in invertebrates
    • Jacklet, J.W. Nitric oxide signaling in invertebrates. Invert. Neurosci. 1997, 3, 1-14.
    • (1997) Invert. Neurosci , vol.3 , pp. 1-14
    • Jacklet, J.W.1
  • 4
    • 41849130604 scopus 로고    scopus 로고
    • Nitric oxide synthesis and signalling in plants
    • Wilson, I.D.; Neill, S.J.; Hancock, J.T. Nitric oxide synthesis and signalling in plants. Plant Cell Environ. 2008, 31, 622-631.
    • (2008) Plant Cell Environ , vol.31 , pp. 622-631
    • Wilson, I.D.1    Neill, S.J.2    Hancock, J.T.3
  • 6
    • 0033989030 scopus 로고    scopus 로고
    • The yin and yang of nitricoxide: Reflections on the physiology and pathophysiology of no
    • Bentz, B.G.; Simmons, R.L.; Haines, G.K., III; Radosevich, J.A. The yin and yang of nitricoxide: Reflections on the physiology and pathophysiology of no. Head Neck 2000, 22, 71-83.
    • (2000) Head Neck , vol.22 , pp. 71-83
    • Bentz, B.G.1    Simmons, R.L.2    Haines III, G.K.3    Radosevich, J.A.4
  • 7
    • 34247613216 scopus 로고    scopus 로고
    • Nitric oxide, a double edged sword in cancer biology: Searching for therapeutic opportunities
    • Mocellin, S.; Bronte, V.; Nitti, D. Nitric oxide, a double edged sword in cancer biology: Searching for therapeutic opportunities. Med. Res. Rev. 2007, 27, 317-352.
    • (2007) Med. Res. Rev , vol.27 , pp. 317-352
    • Mocellin, S.1    Bronte, V.2    Nitti, D.3
  • 8
    • 0028132836 scopus 로고
    • Redox signaling: Nitrosylation and related target interactions of nitric oxide
    • Stamler, J.S. Redox signaling: Nitrosylation and related target interactions of nitric oxide. Cell 1994, 78, 931-936.
    • (1994) Cell , vol.78 , pp. 931-936
    • Stamler, J.S.1
  • 9
    • 0023142137 scopus 로고
    • L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells
    • Hibbs, J.B.; Vavrin, A.; Taintor, R.R. L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells. J. Immunol. 1987, 138, 550-565.
    • (1987) J. Immunol , vol.138 , pp. 550-565
    • Hibbs, J.B.1    Vavrin, A.2    Taintor, R.R.3
  • 11
    • 45149088480 scopus 로고    scopus 로고
    • Concepts of neural nitric oxide-mediated transmission
    • Garthwaite, J. Concepts of neural nitric oxide-mediated transmission. Eur. J. Neurosci. 2008, 27, 2783-2802.
    • (2008) Eur. J. Neurosci , vol.27 , pp. 2783-2802
    • Garthwaite, J.1
  • 12
    • 14644444482 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase regulates brain-derived neurotrophic factor expression and neurogenesis after stroke in mice
    • Chen, J.; Zacharek, A.; Zhang, C.; Jiang, H.; Li, Y.; Roberts, C.; Lu, M.; Kapke, A.; Chopp, M. Endothelial nitric oxide synthase regulates brain-derived neurotrophic factor expression and neurogenesis after stroke in mice. J. Neurosci. 2005, 25, 2366-2375.
    • (2005) J. Neurosci , vol.25 , pp. 2366-2375
    • Chen, J.1    Zacharek, A.2    Zhang, C.3    Jiang, H.4    Li, Y.5    Roberts, C.6    Lu, M.7    Kapke, A.8    Chopp, M.9
  • 14
    • 0035139227 scopus 로고    scopus 로고
    • Physiology of nitric oxide in skeletal muscle
    • Stamler, J.S.; Meissner, G. Physiology of nitric oxide in skeletal muscle. Physiol. Rev. 2001, 81, 209-237.
    • (2001) Physiol. Rev , vol.81 , pp. 209-237
    • Stamler, J.S.1    Meissner, G.2
  • 15
    • 46049093360 scopus 로고    scopus 로고
    • Nitric oxide, c-type natriuretic peptide and cgmp as regulators of endochondral ossification
    • Teixeira, C.C.; Agoston, H.; Beier, F. Nitric oxide, c-type natriuretic peptide and cgmp as regulators of endochondral ossification. Dev. Biol. 2008, 319, 171-178.
    • (2008) Dev. Biol , vol.319 , pp. 171-178
    • Teixeira, C.C.1    Agoston, H.2    Beier, F.3
  • 17
    • 42349113464 scopus 로고    scopus 로고
    • Diabetes and vessel wall remodelling: From mechanistic insights to regenerative therapies
    • Spinetti, G.; Kraenkel, N.; Emanueli, C.; Madeddu, P. Diabetes and vessel wall remodelling: From mechanistic insights to regenerative therapies. Cardiovasc. Res. 2008, 78, 265-273.
    • (2008) Cardiovasc. Res , vol.78 , pp. 265-273
    • Spinetti, G.1    Kraenkel, N.2    Emanueli, C.3    Madeddu, P.4
  • 18
    • 2942665472 scopus 로고    scopus 로고
    • Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide
    • USA
    • Thomas, D.D.; Espey, M.G.; Ridnour, L.A.; Hofseth, L.J.; Mancardi, D.; Harris, C.C.; Wink, D.A. Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide. Proc. Natl. Acad. Sci. USA 2004, 101, 8894-8899.
    • (2004) Proc. Natl. Acad. Sci , vol.101 , pp. 8894-8899
    • Thomas, D.D.1    Espey, M.G.2    Ridnour, L.A.3    Hofseth, L.J.4    Mancardi, D.5    Harris, C.C.6    Wink, D.A.7
  • 19
    • 1242321336 scopus 로고    scopus 로고
    • The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations
    • Ridnour, L.A.; Thomas, D.D.; Mancardi, D.; Espey, M.G.; Miranda, K.M.; Paolocci, N.; Feelisch, M.; Fukuto, J.; Wink, D.A. The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations. Biol. Chem. 2004, 385, 1-10.
    • (2004) Biol. Chem , vol.385 , pp. 1-10
    • Ridnour, L.A.1    Thomas, D.D.2    Mancardi, D.3    Espey, M.G.4    Miranda, K.M.5    Paolocci, N.6    Feelisch, M.7    Fukuto, J.8    Wink, D.A.9
  • 20
    • 33646908329 scopus 로고    scopus 로고
    • Nitric oxide-dependent negative feedback of parp-1 trans-activation of the inducible nitric-oxide synthase gene
    • Yu, Z.; Kuncewicz, T.; Dubinsky, W.P.; Kone, B.C. Nitric oxide-dependent negative feedback of parp-1 trans-activation of the inducible nitric-oxide synthase gene. J. Biol. Chem. 2006, 281, 9101-9109.
    • (2006) J. Biol. Chem , vol.281 , pp. 9101-9109
    • Yu, Z.1    Kuncewicz, T.2    Dubinsky, W.P.3    Kone, B.C.4
  • 21
    • 62549126916 scopus 로고    scopus 로고
    • Nitric oxide: Cancer target or anticancer agent
    • Mocellin, S. Nitric oxide: Cancer target or anticancer agent? Curr. Cancer Drug Targets 2009, 9, 214-236.
    • (2009) Curr. Cancer Drug Targets , vol.9 , pp. 214-236
    • Mocellin, S.1
  • 25
    • 2642597076 scopus 로고    scopus 로고
    • Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
    • Papapetropoulos, A.; Garcia-Cardena, G.; Madri, J.A.; Sessa, W.C. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J. Clin. Invest. 1997, 100, 3131-3139.
    • (1997) J. Clin. Invest , vol.100 , pp. 3131-3139
    • Papapetropoulos, A.1    Garcia-Cardena, G.2    Madri, J.A.3    Sessa, W.C.4
  • 26
    • 2942686015 scopus 로고    scopus 로고
    • Is inducible nitric oxide synthase a target for chemoprevention
    • Crowell, J.A.; Steele, V.E.; Sigman, C.C.; Fay, J.R. Is inducible nitric oxide synthase a target for chemoprevention? Mol. Cancer Ther. 2003, 2, 815-823.
    • (2003) Mol. Cancer Ther , vol.2 , pp. 815-823
    • Crowell, J.A.1    Steele, V.E.2    Sigman, C.C.3    Fay, J.R.4
  • 28
    • 0031018039 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with l-arginine
    • Tozer, G.M.; Prise, V.E.; Chaplin, D.J. Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with l-arginine. Cancer Res. 1997, 57, 948-955.
    • (1997) Cancer Res , vol.57 , pp. 948-955
    • Tozer, G.M.1    Prise, V.E.2    Chaplin, D.J.3
  • 29
    • 0027739308 scopus 로고
    • Inhibition of nitric oxide synthesis increases blood pressure in healthy humans
    • Haynes, W.G.; Noon, J.P.; Walker, B.R.; Webb, D.J. Inhibition of nitric oxide synthesis increases blood pressure in healthy humans. J. Hypertens. 1993, 11, 1375-1380.
    • (1993) J. Hypertens , vol.11 , pp. 1375-1380
    • Haynes, W.G.1    Noon, J.P.2    Walker, B.R.3    Webb, D.J.4
  • 31
    • 0033989398 scopus 로고    scopus 로고
    • Increased protein nitrosylation in head and neck squamous cell carcinoma
    • Bentz, B.G.; Haines, G.K., III; Radosevich, J.A. Increased protein nitrosylation in head and neck squamous cell carcinoma. Head Neck 2000, 22, 64-70.
    • (2000) Head Neck , vol.22 , pp. 64-70
    • Bentz, B.G.1    Haines III, G.K.2    Radosevich, J.A.3
  • 35
    • 0029071838 scopus 로고
    • Role of n-nitroso compounds (noc) and n-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to noc
    • Mirvish, S.S. Role of n-nitroso compounds (noc) and n-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to noc. Cancer Lett. 1995, 93, 17-48.
    • (1995) Cancer Lett , vol.93 , pp. 17-48
    • Mirvish, S.S.1
  • 36
    • 77049302117 scopus 로고
    • The determination of the velocity constants of four successive reactions of carbon monoxide with sheep haemoglobin
    • Gibson, Q.H.; Roughton, F.J. The determination of the velocity constants of four successive reactions of carbon monoxide with sheep haemoglobin. Proc. Soc. Ser. B: Biol. Sci. Lond. 1957, 206-224.
    • (1957) Proc. Soc. Ser. B: Biol. Sci. Lond , pp. 206-224
    • Gibson, Q.H.1    Roughton, F.J.2
  • 38
    • 46649090918 scopus 로고    scopus 로고
    • Protein tyrosine nitration--functional alteration or just a biomarker
    • Souza, J.M.; Peluffo, G.; Radi, R. Protein tyrosine nitration--functional alteration or just a biomarker? Free Radic. Biol. Med. 2008, 45, 357-366.
    • (2008) Free Radic. Biol. Med , vol.45 , pp. 357-366
    • Souza, J.M.1    Peluffo, G.2    Radi, R.3
  • 40
    • 0343468123 scopus 로고    scopus 로고
    • Nos-mapping of Human Nasal Mucosa Under Physiologic and Pathophysiological Conditions
    • Moncada, S., Stamler, J., Gross, S., Higgs, E.A., Eds.; Portland Press: London, UK
    • Michel, O.; Bloch, W.; Rocker, J. Nos-mapping of human nasal mucosa under physiologic and pathophysiological conditions. In Proceedings of the Fourth International Meeting on the Biology of Nitric Oxide. Moncada, S., Stamler, J., Gross, S., Higgs, E.A., Eds.; Portland Press: London, UK, 1996; p. 230.
    • (1996) Proceedings Of The Fourth International Meeting On The Biology Of Nitric Oxide , pp. 230
    • Michel, O.1    Bloch, W.2    Rocker, J.3
  • 41
    • 0033038758 scopus 로고    scopus 로고
    • Concise review of the glutathione s-transferases and their significance to toxicology
    • Eaton, D.L.; Bammler, T.K. Concise review of the glutathione s-transferases and their significance to toxicology. Toxicol. Sci. 1999, 49, 156-164.
    • (1999) Toxicol. Sci , vol.49 , pp. 156-164
    • Eaton, D.L.1    Bammler, T.K.2
  • 42
    • 0035075872 scopus 로고    scopus 로고
    • Genetic deletions of glutathione-s-transferase as a risk factor in squamous cell carcinoma of the larynx: A preliminary report
    • Hanna, E.; MacLeod, S.; Vural, E.; Lang, N. Genetic deletions of glutathione-s-transferase as a risk factor in squamous cell carcinoma of the larynx: A preliminary report. Am. J. Otolaryngol. 2001, 22, 121-123.
    • (2001) Am. J. Otolaryngol , vol.22 , pp. 121-123
    • Hanna, E.1    Macleod, S.2    Vural, E.3    Lang, N.4
  • 43
    • 0023756891 scopus 로고
    • Protective role of glutathione and glutathione transferases in mutagenesis and carcinogenesis
    • Ketterer, B. Protective role of glutathione and glutathione transferases in mutagenesis and carcinogenesis. Mutat. Res. 1988, 202, 343-361.
    • (1988) Mutat. Res , vol.202 , pp. 343-361
    • Ketterer, B.1
  • 44
  • 45
    • 33645111448 scopus 로고    scopus 로고
    • Glutathione s-transferase polymorphisms: Cancer incidence and therapy
    • McIlwain, C.C.; Townsend, D.M.; Tew, K.D. Glutathione s-transferase polymorphisms: Cancer incidence and therapy. Oncogene 2006, 25, 1639-1648.
    • (2006) Oncogene , vol.25 , pp. 1639-1648
    • McIlwain, C.C.1    Townsend, D.M.2    Tew, K.D.3
  • 46
    • 53249119776 scopus 로고    scopus 로고
    • Elevated expression of glutathione s-transferase pi and p53 confers poor prognosis in head and neck cancer patients treated with chemoradiotherapy but not radiotherapy alone
    • Schumaker, L.; Nikitakis, N.; Goloubeva, O.; Tan, M.; Taylor, R.; Cullen, K.J. Elevated expression of glutathione s-transferase pi and p53 confers poor prognosis in head and neck cancer patients treated with chemoradiotherapy but not radiotherapy alone. Clin. Cancer Res. 2008, 14, 5877-5883.
    • (2008) Clin. Cancer Res , vol.14 , pp. 5877-5883
    • Schumaker, L.1    Nikitakis, N.2    Goloubeva, O.3    Tan, M.4    Taylor, R.5    Cullen, K.J.6
  • 47
    • 0030899372 scopus 로고    scopus 로고
    • Molecular cloning, characterization, and expression in escherichia coli of full-length cdnas of three human glutathione s-transferase pi gene variants. Evidence for differential catalytic activity of the encoded proteins
    • Ali-Osman, F.; Akande, O.; Antoun, G.; Mao, J.X.; Buolamwini, J. Molecular cloning, characterization, and expression in escherichia coli of full-length cdnas of three human glutathione s-transferase pi gene variants. Evidence for differential catalytic activity of the encoded proteins. J. Biol. Chem. 1997, 272, 10004-10012.
    • (1997) J. Biol. Chem , vol.272 , pp. 10004-10012
    • Ali-Osman, F.1    Akande, O.2    Antoun, G.3    Mao, J.X.4    Buolamwini, J.5
  • 48
    • 0032734575 scopus 로고    scopus 로고
    • Overexpression of glutathione s- transferase pi enhances the adduct formation of cisplatin with glutathione in human cancer cells
    • Goto, S.; Iida, T.; Cho, S.; Oka, M.; Kohno, S.; Kondo, T. Overexpression of glutathione s- transferase pi enhances the adduct formation of cisplatin with glutathione in human cancer cells. Free Radic. Res. 1999, 31, 549-558.
    • (1999) Free Radic. Res , vol.31 , pp. 549-558
    • Goto, S.1    Iida, T.2    Cho, S.3    Oka, M.4    Kohno, S.5    Kondo, T.6
  • 49
    • 0037134707 scopus 로고    scopus 로고
    • Association between glutathione s-transferase p1, t1, and m1 genetic polymorphism and survival of patients with metastatic colorectal cancer
    • Stoehlmacher, J.; Park, D.J.; Zhang, W.; Groshen, S.; Tsao-Wei, D.D.; Yu, M.C.; Lenz, H.J. Association between glutathione s-transferase p1, t1, and m1 genetic polymorphism and survival of patients with metastatic colorectal cancer. J. Natl. Cancer Inst. 2002, 94, 936-942.
    • (2002) J. Natl. Cancer Inst , vol.94 , pp. 936-942
    • Stoehlmacher, J.1    Park, D.J.2    Zhang, W.3    Groshen, S.4    Tsao-Wei, D.D.5    Yu, M.C.6    Lenz, H.J.7
  • 50
  • 51
    • 0028106016 scopus 로고
    • Glutathione-associated enzymes in anticancer drug resistance
    • Tew, K.D. Glutathione-associated enzymes in anticancer drug resistance. Cancer Res. 1994, 54, 4313-4320.
    • (1994) Cancer Res , vol.54 , pp. 4313-4320
    • Tew, K.D.1
  • 52
    • 0030932313 scopus 로고    scopus 로고
    • Correlated expression of glutathione s-transferase-pi and c-jun or other oncogene products in human squamous cell carcinomas of the head and neck: Relevance to relapse after radiation therapy
    • Miura, K.; Suzuki, S.; Tanita, J.; Shinkawa, H.; Satoh, K.; Tsuchida, S. Correlated expression of glutathione s-transferase-pi and c-jun or other oncogene products in human squamous cell carcinomas of the head and neck: Relevance to relapse after radiation therapy. Jpn. J. Cancer Res. 1997, 88, 143-151.
    • (1997) Jpn. J. Cancer Res , vol.88 , pp. 143-151
    • Miura, K.1    Suzuki, S.2    Tanita, J.3    Shinkawa, H.4    Satoh, K.5    Tsuchida, S.6
  • 53
    • 0028811596 scopus 로고
    • Second primary head and neck squamous cell carcinoma predicted by the glutathione s- transferase expression in healthy tissue in the direct vicinity of the first tumor
    • Bongers, V.; Snow, G.B.; de Vries, N.; Cattan, A.R.; Hall, A.G.; van der Waal, I.; Braakhuis, B.J. Second primary head and neck squamous cell carcinoma predicted by the glutathione s- transferase expression in healthy tissue in the direct vicinity of the first tumor. Lab. Invest. 1995, 73, 503-510.
    • (1995) Lab. Invest , vol.73 , pp. 503-510
    • Bongers, V.1    Snow, G.B.2    de Vries, N.3    Cattan, A.R.4    Hall, A.G.5    van der Waal, I.6    Braakhuis, B.J.7
  • 54
    • 0344631746 scopus 로고    scopus 로고
    • Nitric oxide synthase type 3 is increased in squamous hyperplasia, dysplasia, and squamous cell carcinoma of the head and neck
    • Bentz, B.G.; Haines, G.K., III; Lingen, M.W.; Pelzer, H.J.; Hanson, D.G.; Radosevich, J.A. Nitric oxide synthase type 3 is increased in squamous hyperplasia, dysplasia, and squamous cell carcinoma of the head and neck. Ann. Otol. Rhinol. Laryngol. 1999, 108, 781-787.
    • (1999) Ann. Otol. Rhinol. Laryngol , vol.108 , pp. 781-787
    • Bentz, B.G.1    Haines III, G.K.2    Lingen, M.W.3    Pelzer, H.J.4    Hanson, D.G.5    Radosevich, J.A.6
  • 55
    • 0033771046 scopus 로고    scopus 로고
    • Glutathione s-transferase pi in squamous cell carcinoma of the head and neck
    • Bentz, B.G.; Haines, G.K., III; Radosevich, J.A. Glutathione s-transferase pi in squamous cell carcinoma of the head and neck. Laryngoscope 2000, 110, 1642-1647.
    • (2000) Laryngoscope , vol.110 , pp. 1642-1647
    • Bentz, B.G.1    Haines III, G.K.2    Radosevich, J.A.3
  • 56
    • 0344631746 scopus 로고    scopus 로고
    • Nitric oxide synthase type 3 is increased in squamous hyperplasia, dysplasia, and squamous cell carcinoma of the head and neck
    • Bentz, B.G.; Haines, G.K., III; Lingen, M.W.; Pelzer, H.J.; Hanson, D.G.; Radosevich, J.A. Nitric oxide synthase type 3 is increased in squamous hyperplasia, dysplasia, and squamous cell carcinoma of the head and neck. Ann. Otol. Rhinol. Laryngol. 1999, 108, 781-787.
    • (1999) Ann. Otol. Rhinol. Laryngol , vol.108 , pp. 781-787
    • Bentz, B.G.1    Haines III, G.K.2    Lingen, M.W.3    Pelzer, H.J.4    Hanson, D.G.5    Radosevich, J.A.6
  • 57
    • 0033771046 scopus 로고    scopus 로고
    • Glutathione s-transferase pi in squamous cell carcinoma of the head and neck
    • Bentz, B.G.; Haines, G.K., III; Radosevich, J.A. Glutathione s-transferase pi in squamous cell carcinoma of the head and neck. Laryngoscope 2000, 110, 1642-1647.
    • (2000) Laryngoscope , vol.110 , pp. 1642-1647
    • Bentz, B.G.1    Haines III, G.K.2    Radosevich, J.A.3
  • 58
    • 66349114311 scopus 로고    scopus 로고
    • Nitric oxide induces early viral transcription coincident with increased DNA damage and mutation rates in human papillomavirus-infected cells
    • Wei, L.; Gravitt, P.E.; Song, H.; Maldonado, A.M.; Ozbun, M.A. Nitric oxide induces early viral transcription coincident with increased DNA damage and mutation rates in human papillomavirus-infected cells. Cancer Res. 2009, 69, 4878-4884.
    • (2009) Cancer Res , vol.69 , pp. 4878-4884
    • Wei, L.1    Gravitt, P.E.2    Song, H.3    Maldonado, A.M.4    Ozbun, M.A.5
  • 61
    • 43849085332 scopus 로고    scopus 로고
    • Review article: Steroid hormones and uterine vascular adaptation to pregnancy
    • Chang, K.; Lubo, Z. Review article: Steroid hormones and uterine vascular adaptation to pregnancy. Reprod. Sci. 2008, 15, 336-348.
    • (2008) Reprod. Sci , vol.15 , pp. 336-348
    • Chang, K.1    Lubo, Z.2
  • 62
    • 34249894787 scopus 로고    scopus 로고
    • Nitrative and oxidative DNA damage in cervical intraepithelial neoplasia associated with human papilloma virus infection
    • Hiraku, Y.; Tabata, T.; Ma, N.; Murata, M.; Ding, X.; Kawanishi, S. Nitrative and oxidative DNA damage in cervical intraepithelial neoplasia associated with human papilloma virus infection. Cancer Sci. 2007, 98, 964-972.
    • (2007) Cancer Sci , vol.98 , pp. 964-972
    • Hiraku, Y.1    Tabata, T.2    Ma, N.3    Murata, M.4    Ding, X.5    Kawanishi, S.6
  • 63
    • 42949176956 scopus 로고    scopus 로고
    • Local profile of cytokines and nitric oxide in patients with bacterial vaginosis and cervical intraepithelial neoplasia
    • Tavares-Murta, B.M.; de Resende, A.D.; Cunha, F.Q.; Murta, E.F. Local profile of cytokines and nitric oxide in patients with bacterial vaginosis and cervical intraepithelial neoplasia. Eur. J. Obstet. Gynecol. Reprod. Biol. 2008, 138, 93-99.
    • (2008) Eur. J. Obstet. Gynecol. Reprod. Biol , vol.138 , pp. 93-99
    • Tavares-Murta, B.M.1    de Resende, A.D.2    Cunha, F.Q.3    Murta, E.F.4
  • 64
    • 0021964203 scopus 로고
    • Prooxidant states and tumor promotion
    • Cerutti, P.A. Prooxidant states and tumor promotion. Science 1985, 227, 375-381.
    • (1985) Science , vol.227 , pp. 375-381
    • Cerutti, P.A.1
  • 65
    • 35648983903 scopus 로고    scopus 로고
    • Inflammation and cancer: An ancient link with novel potentials
    • Hussain, S.P.; Harris, C.C. Inflammation and cancer: An ancient link with novel potentials. Int. J. Cancer 2007, 121, 2373-2380.
    • (2007) Int. J. Cancer , vol.121 , pp. 2373-2380
    • Hussain, S.P.1    Harris, C.C.2
  • 67
    • 33745847542 scopus 로고    scopus 로고
    • Increased etheno-DNA adducts in affected tissues of patients suffering from crohn's disease, ulcerative colitis, and chronic pancreatitis
    • Nair, J.; Gansauge, F.; Beger, H.; Dolara, P.; Winde, G.; Bartsch, H. Increased etheno-DNA adducts in affected tissues of patients suffering from crohn's disease, ulcerative colitis, and chronic pancreatitis. Antioxid. Redox. Signal 2006, 8, 1003-1010.
    • (2006) Antioxid. Redox. Signal , vol.8 , pp. 1003-1010
    • Nair, J.1    Gansauge, F.2    Beger, H.3    Dolara, P.4    Winde, G.5    Bartsch, H.6
  • 68
    • 0026035117 scopus 로고
    • Inflammation and oxidative stress in carcinogenesis
    • Cerutti, P.A.; Trump, B.F. Inflammation and oxidative stress in carcinogenesis. Cancer Cells 1991, 3, 1-7.
    • (1991) Cancer Cells , vol.3 , pp. 1-7
    • Cerutti, P.A.1    Trump, B.F.2
  • 69
    • 0036098552 scopus 로고    scopus 로고
    • Ap-1 as a regulator of cell life and death
    • Shaulian, E.; Karin, M. Ap-1 as a regulator of cell life and death. Nat. Cell Biol. 2002, 4, E131-E136.
    • (2002) Nat. Cell Biol , vol.4
    • Shaulian, E.1    Karin, M.2
  • 73
    • 0033780886 scopus 로고    scopus 로고
    • Nitric oxide upregulates expression of DNA-pkcs to protect cells from DNA-damaging anti-tumour agents
    • Xu, W.; Liu, L.; Smith, G.C.; Charles, G. Nitric oxide upregulates expression of DNA-pkcs to protect cells from DNA-damaging anti-tumour agents. Nat. Cell Biol. 2000, 2, 339-345.
    • (2000) Nat. Cell Biol , vol.2 , pp. 339-345
    • Xu, W.1    Liu, L.2    Smith, G.C.3    Charles, G.4
  • 74
    • 0036960243 scopus 로고    scopus 로고
    • The changing concept of epigenetics
    • Jablonka, E.; Lamb, M.J. The changing concept of epigenetics. Ann. NY Acad. Sci. 2002, 981, 82-96.
    • (2002) Ann. NY Acad. Sci , vol.981 , pp. 82-96
    • Jablonka, E.1    Lamb, M.J.2
  • 75
    • 72849115191 scopus 로고    scopus 로고
    • Overview of mammalian genome special issue on epigenetics
    • Peters, J. Overview of mammalian genome special issue on epigenetics. Mamm. Genome 2009, 20, 529-531.
    • (2009) Mamm. Genome , vol.20 , pp. 529-531
    • Peters, J.1
  • 76
  • 77
    • 16544395591 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • Das, P.M.; Singal, R. DNA methylation and cancer. J. Clin. Oncol. 2004, 22, 4632-4642.
    • (2004) J. Clin. Oncol , vol.22 , pp. 4632-4642
    • Das, P.M.1    Singal, R.2
  • 79
    • 24344477093 scopus 로고    scopus 로고
    • Gametes and embryo epigenetic reprogramming affect developmental outcome: Implication for assisted reproductive technologies
    • Jacob, S.; Moley, K.H. Gametes and embryo epigenetic reprogramming affect developmental outcome: Implication for assisted reproductive technologies. Pediatr. Res. 2005, 58, 437-446.
    • (2005) Pediatr. Res , vol.58 , pp. 437-446
    • Jacob, S.1    Moley, K.H.2
  • 80
    • 34548757364 scopus 로고    scopus 로고
    • Epigenetic reprogramming and imprinting in origins of disease
    • Tang, W.Y.; Ho, S.M. Epigenetic reprogramming and imprinting in origins of disease. Rev. Endocr. Metab. Disord. 2007, 8, 173-182.
    • (2007) Rev. Endocr. Metab. Disord , vol.8 , pp. 173-182
    • Tang, W.Y.1    Ho, S.M.2
  • 81
    • 33847614418 scopus 로고    scopus 로고
    • Covalent modification of DNA regulates memory formation
    • Miller, C.A.; Sweatt, J.D. Covalent modification of DNA regulates memory formation. Neuron 2007, 53, 857-869.
    • (2007) Neuron , vol.53 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 82
    • 42549126341 scopus 로고    scopus 로고
    • Epigenetic regulation of vascular endothelial gene expression
    • Matouk, C.C.; Marsden, P.A. Epigenetic regulation of vascular endothelial gene expression. Circ. Res. 2008, 102, 873-887.
    • (2008) Circ. Res , vol.102 , pp. 873-887
    • Matouk, C.C.1    Marsden, P.A.2
  • 83
    • 53249093709 scopus 로고    scopus 로고
    • The cell biology of DNA methylation in mammals
    • Prokhortchouk, E.; Defossez, P.A. The cell biology of DNA methylation in mammals. Biochim. Biophys. Acta 2008, 1783, 2167-2173.
    • (2008) Biochim. Biophys. Acta , vol.1783 , pp. 2167-2173
    • Prokhortchouk, E.1    Defossez, P.A.2
  • 84
    • 0037072601 scopus 로고    scopus 로고
    • Molecular biology. Chromatin higher order folding--wrapping up transcription
    • Horn, P.J.; Peterson, C.L. Molecular biology. Chromatin higher order folding--wrapping up transcription. Science 2002, 297, 1824-1827.
    • (2002) Science , vol.297 , pp. 1824-1827
    • Horn, P.J.1    Peterson, C.L.2
  • 85
    • 60149088848 scopus 로고    scopus 로고
    • Origins and mechanisms of mirnas and sirnas
    • Carthew, R.W.; Sontheimer, E.J. Origins and mechanisms of mirnas and sirnas. Cell 2009, 136, 642-655.
    • (2009) Cell , vol.136 , pp. 642-655
    • Carthew, R.W.1    Sontheimer, E.J.2
  • 86
    • 1842411320 scopus 로고    scopus 로고
    • Crystal structure of the nucleosome core particle at 2.8 a resolution
    • Luger, K.; Mader, A.W.; Richmond, R.K.; Sargent, D.F.; Richmond, T.J. Crystal structure of the nucleosome core particle at 2.8 a resolution. Nature 1997, 389, 251-260.
    • (1997) Nature , vol.389 , pp. 251-260
    • Luger, K.1    Mader, A.W.2    Richmond, R.K.3    Sargent, D.F.4    Richmond, T.J.5
  • 87
    • 0036089388 scopus 로고    scopus 로고
    • Conformational dynamics of the chromatin fiber in solution: Determinants, mechanisms, and functions
    • Hansen, J.C. Conformational dynamics of the chromatin fiber in solution: Determinants, mechanisms, and functions. Ann. Rev. Biophys. Biomol. Struct. 2002, 31, 361-392.
    • (2002) Ann. Rev. Biophys. Biomol. Struct , vol.31 , pp. 361-392
    • Hansen, J.C.1
  • 88
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein, T.; Allis, C.D. Translating the histone code. Science 2001, 293, 1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 89
    • 0345603004 scopus 로고    scopus 로고
    • The cpg island searcher: A new www resource
    • Takai, D.; Jones, P.A. The cpg island searcher: A new www resource. In Silico Biol. 2003, 3, 235-240.
    • (2003) In Silico Biol , vol.3 , pp. 235-240
    • Takai, D.1    Jones, P.A.2
  • 90
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller, M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat. Rev. Genet. 2007, 8, 286-298.
    • (2007) Nat. Rev. Genet , vol.8 , pp. 286-298
    • Esteller, M.1
  • 91
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones, P.A.; Baylin, S.B. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 2002, 3, 415-428.
    • (2002) Nat. Rev. Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 92
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: The mark and its mediators
    • Klose, R.J.; Bird, A.P. Genomic DNA methylation: The mark and its mediators. Trends Biochem. Sci. 2006, 31, 89-97.
    • (2006) Trends Biochem. Sci , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 93
    • 0037133565 scopus 로고    scopus 로고
    • Comprehensive analysis of cpg islands in human chromosomes 21 and 22
    • Takai, D.; Jones, P.A. Comprehensive analysis of cpg islands in human chromosomes 21 and 22. Proc. Natl. Acad. Sci. USA 2002, 99, 3740-3745.
    • (2002) Proc. Natl. Acad. Sci USA , vol.99 , pp. 3740-3745
    • Takai, D.1    Jones, P.A.2
  • 94
    • 0036389638 scopus 로고    scopus 로고
    • Brca1 methylation: A significant role in tumour development?
    • Catteau, A.; Morris, J.R. Brca1 methylation: A significant role in tumour development? Semin. Cancer Biol. 2002, 12, 359-371.
    • (2002) Semin. Cancer Biol , vol.12 , pp. 359-371
    • Catteau, A.1    Morris, J.R.2
  • 95
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger, G.; Liang, G.; Aparicio, A.; Jones, P.A. Epigenetics in human disease and prospects for epigenetic therapy. Nature 2004, 429, 457-463.
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 96
    • 0036902962 scopus 로고    scopus 로고
    • DNA methylation and demethylating drugs in myelodysplastic syndromes and secondary leukemias
    • Leone, G.; Teofili, L.; Voso, M.T.; Lubbert, M. DNA methylation and demethylating drugs in myelodysplastic syndromes and secondary leukemias. Haematologica 2002, 87, 1324-1341.
    • (2002) Haematologica , vol.87 , pp. 1324-1341
    • Leone, G.1    Teofili, L.2    Voso, M.T.3    Lubbert, M.4
  • 97
    • 0037068329 scopus 로고    scopus 로고
    • DNA methylation analysis: A powerful new tool for lung cancer diagnosis
    • Tsou, J.A.; Hagen, J.A.; Carpenter, C.L.; Laird-Offringa, I.A. DNA methylation analysis: A powerful new tool for lung cancer diagnosis. Oncogene 2002, 21, 5450-5461.
    • (2002) Oncogene , vol.21 , pp. 5450-5461
    • Tsou, J.A.1    Hagen, J.A.2    Carpenter, C.L.3    Laird-Offringa, I.A.4
  • 98
    • 77950867183 scopus 로고    scopus 로고
    • Epigenetic regulation of oligodendrocyte identity
    • Liu, J.; Casaccia, P. Epigenetic regulation of oligodendrocyte identity. Trends Neurosci. 2010, 33, 193-201.
    • (2010) Trends Neurosci , vol.33 , pp. 193-201
    • Liu, J.1    Casaccia, P.2
  • 99
  • 100
    • 77955070735 scopus 로고    scopus 로고
    • Cpg island methylator phenotype in colrectal cancer: A current perspective
    • Goel, A. Cpg island methylator phenotype in colrectal cancer: A current perspective. Curr. Colorect. Cancer Rep. 2008, 77-83.
    • (2008) Curr. Colorect. Cancer Rep , pp. 77-83
    • Goel, A.1
  • 101
    • 67651173046 scopus 로고    scopus 로고
    • Promoter methylation in the genesis of gastrointestinal cancer
    • Boland, R. Promoter methylation in the genesis of gastrointestinal cancer. Yonsei Med. J. 2009, 50, 309-321.
    • (2009) Yonsei Med. J , vol.50 , pp. 309-321
    • Boland, R.1
  • 102
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein, B.; Kinzler, K.W. Cancer genes and the pathways they control. Nat. Med. 2004, 10, 789-799.
    • (2004) Nat. Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 103
    • 0023230209 scopus 로고
    • Hypomethylation of DNA in pathological conditions of the human prostate
    • Bedford, M.T.; van Helden, P.D. Hypomethylation of DNA in pathological conditions of the human prostate. Cancer Res. 1987, 47, 5274-5276.
    • (1987) Cancer Res , vol.47 , pp. 5274-5276
    • Bedford, M.T.1    van Helden, P.D.2
  • 104
    • 0037068353 scopus 로고    scopus 로고
    • DNA methylation in cancer: Too much, but also too little
    • Ehrlich, M. DNA methylation in cancer: Too much, but also too little. Oncogene 2002, 21, 5400-5413.
    • (2002) Oncogene , vol.21 , pp. 5400-5413
    • Ehrlich, M.1
  • 110
    • 0037099625 scopus 로고    scopus 로고
    • Epigenetic factors controlling the brca1 and brca2 genes in sporadic ovarian cancer
    • Chan, K.Y.; Ozcelik, H.; Cheung, A.N.; Ngan, H.Y.; Khoo, U.S. Epigenetic factors controlling the brca1 and brca2 genes in sporadic ovarian cancer. Cancer Res. 2002, 62, 4151-4156.
    • (2002) Cancer Res , vol.62 , pp. 4151-4156
    • Chan, K.Y.1    Ozcelik, H.2    Cheung, A.N.3    Ngan, H.Y.4    Khoo, U.S.5
  • 111
    • 0030843274 scopus 로고    scopus 로고
    • Methylation of the brca1 gene in sporadic breast cancer
    • Dobrovic, A.; Simpfendorfer, D. Methylation of the brca1 gene in sporadic breast cancer. Cancer Res. 1997, 57, 3347-3350.
    • (1997) Cancer Res , vol.57 , pp. 3347-3350
    • Dobrovic, A.1    Simpfendorfer, D.2
  • 113
    • 0031655803 scopus 로고    scopus 로고
    • Loss of p16/ink4a protein expression in non-hodgkin's lymphomas is a frequent finding associated with tumor progression
    • Villuendas, R. Loss of p16/ink4a protein expression in non-hodgkin's lymphomas is a frequent finding associated with tumor progression. Am. J. Pathol. 1998, 887-897.
    • (1998) Am. J. Pathol , pp. 887-897
    • Villuendas, R.1
  • 115
    • 15144350589 scopus 로고    scopus 로고
    • Distinct patterns of e-cadherin cpg island methylation in papillary, follicular, hurthle's cell, and poorly differentiated human thyroid carcinoma
    • Graff, J.R.; Greenberg, V.E.; Herman, J.G.; Westra, W.H.; Boghaert, E.R.; Ain, K.B.; Saji, M.; Zeiger, M.A.; Zimmer, S.G.; Baylin, S.B. Distinct patterns of e-cadherin cpg island methylation in papillary, follicular, hurthle's cell, and poorly differentiated human thyroid carcinoma. Cancer Res. 1998, 58, 2063-2066.
    • (1998) Cancer Res , vol.58 , pp. 2063-2066
    • Graff, J.R.1    Greenberg, V.E.2    Herman, J.G.3    Westra, W.H.4    Boghaert, E.R.5    Ain, K.B.6    Saji, M.7    Zeiger, M.A.8    Zimmer, S.G.9    Baylin, S.B.10
  • 116
    • 0036966214 scopus 로고    scopus 로고
    • Promoter methylation status of e-cadherin, hmlh1, and p16 genes in nonneoplastic gastric epithelia
    • Waki, T.; Tamura, G.; Tsuchiya, T.; Sato, K.; Nishizuka, S.; Motoyama, T. Promoter methylation status of e-cadherin, hmlh1, and p16 genes in nonneoplastic gastric epithelia. Am. J. Pathol. 2002, 161, 399-403.
    • (2002) Am. J. Pathol , vol.161 , pp. 399-403
    • Waki, T.1    Tamura, G.2    Tsuchiya, T.3    Sato, K.4    Nishizuka, S.5    Motoyama, T.6
  • 118
    • 0033950894 scopus 로고    scopus 로고
    • Frequent methylation of estrogen receptor in prostate cancer: Correlation with tumor progression
    • Li, L.C.; Chui, R.; Nakajima, K.; Oh, B.R.; Au, H.C.; Dahiya, R. Frequent methylation of estrogen receptor in prostate cancer: Correlation with tumor progression. Cancer Res. 2000, 60, 702-706.
    • (2000) Cancer Res , vol.60 , pp. 702-706
    • Li, L.C.1    Chui, R.2    Nakajima, K.3    Oh, B.R.4    Au, H.C.5    Dahiya, R.6
  • 119
    • 0028152397 scopus 로고
    • Cytidine methylation of regulatory sequences near the pi-class glutathione s-transferase gene accompanies human prostatic carcinogenesis
    • USA
    • Lee, W.H.; Morton, R.A.; Epstein, J.I.; Brooks, J.D.; Campbell, P.A.; Bova, G.S.; Hsieh, W.S.; Isaacs, W.B.; Nelson, W.G. Cytidine methylation of regulatory sequences near the pi-class glutathione s-transferase gene accompanies human prostatic carcinogenesis. Proc. Natl. Acad. Sci. USA 1994, 91, 11733-11737.
    • (1994) Proc. Natl. Acad. Sci , vol.91 , pp. 11733-11737
    • Lee, W.H.1    Morton, R.A.2    Epstein, J.I.3    Brooks, J.D.4    Campbell, P.A.5    Bova, G.S.6    Hsieh, W.S.7    Isaacs, W.B.8    Nelson, W.G.9
  • 121
    • 0034264425 scopus 로고    scopus 로고
    • Not hmsh2 but hmlh1 is frequently silenced by hypermethylation in endometrial cancer but rarely silenced in pancreatic cancer with microsatellite instability
    • Kondo, E. Not hmsh2 but hmlh1 is frequently silenced by hypermethylation in endometrial cancer but rarely silenced in pancreatic cancer with microsatellite instability. Int. J. Oncol. 2000, 535-541.
    • (2000) Int. J. Oncol , pp. 535-541
    • Kondo, E.1
  • 122
    • 0033535612 scopus 로고    scopus 로고
    • A role for methylation of the hmlh1 promoter in loss of hmlh1 expression and drug resistance in ovarian cancer
    • Strathdee, G.; MacKean, M.J.; Illand, M.; Brown, R. A role for methylation of the hmlh1 promoter in loss of hmlh1 expression and drug resistance in ovarian cancer. Oncogene 1999, 18, 2335-2341.
    • (1999) Oncogene , vol.18 , pp. 2335-2341
    • Strathdee, G.1    Mackean, M.J.2    Illand, M.3    Brown, R.4
  • 125
    • 0033179375 scopus 로고    scopus 로고
    • Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia
    • Melki, J.R.; Vincent, P.C.; Clark, S.J. Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. Cancer Res. 1999, 59, 3730-3740.
    • (1999) Cancer Res , vol.59 , pp. 3730-3740
    • Melki, J.R.1    Vincent, P.C.2    Clark, S.J.3
  • 126
    • 0036733566 scopus 로고    scopus 로고
    • Different incidence and pattern of p15ink4b and p16ink4a promoter region hypermethylation in hodgkin's and cd30-positive non-hodgkin's lymphomas
    • Garcia, M.J.; Martinez-Delgado, B.; Cebrian, A.; Martinez, A.; Benitez, J.; Rivas, C. Different incidence and pattern of p15ink4b and p16ink4a promoter region hypermethylation in hodgkin's and cd30-positive non-hodgkin's lymphomas. Am. J. Pathol. 2002, 161, 1007-1013.
    • (2002) Am. J. Pathol , vol.161 , pp. 1007-1013
    • Garcia, M.J.1    Martinez-Delgado, B.2    Cebrian, A.3    Martinez, A.4    Benitez, J.5    Rivas, C.6
  • 127
    • 0030046322 scopus 로고    scopus 로고
    • Hypermethylation-associated inactivation indicates a tumor suppressor role for p15ink4b
    • Herman, J.G.; Jen, J.; Merlo, A.; Baylin, S.B. Hypermethylation-associated inactivation indicates a tumor suppressor role for p15ink4b. Cancer Res. 1996, 56, 722-727.
    • (1996) Cancer Res , vol.56 , pp. 722-727
    • Herman, J.G.1    Jen, J.2    Merlo, A.3    Baylin, S.B.4
  • 128
    • 0035932393 scopus 로고    scopus 로고
    • Methylation associated inactivation of rassf1a from region 3p21.3 in lung, breast and ovarian tumours
    • Agathanggelou, A. Methylation associated inactivation of rassf1a from region 3p21.3 in lung, breast and ovarian tumours. Oncogene 2001, 1509-1518.
    • (2001) Oncogene , pp. 1509-1518
    • Agathanggelou, A.1
  • 130
  • 132
    • 0037434432 scopus 로고    scopus 로고
    • Cpg island methylation status and mutation analysis of the rb1 gene essential promoter region and protein-binding pocket domain in nervous system tumours
    • Gonzalez-Gomez, P.; Bello, M.J.; Alonso, M.E.; Arjona, D.; Lomas, J.; de Campos, J.M.; Isla, A.; Rey, J.A. Cpg island methylation status and mutation analysis of the rb1 gene essential promoter region and protein-binding pocket domain in nervous system tumours. Br. J. Cancer 2003, 88, 109-114.
    • (2003) Br. J. Cancer , vol.88 , pp. 109-114
    • Gonzalez-Gomez, P.1    Bello, M.J.2    Alonso, M.E.3    Arjona, D.4    Lomas, J.5    de Campos, J.M.6    Isla, A.7    Rey, J.A.8
  • 133
    • 34447513434 scopus 로고    scopus 로고
    • Regulation and specificity of s-nitrosylation and denitrosylation
    • Tannenbaum, S.R.; White, F.M. Regulation and specificity of s-nitrosylation and denitrosylation. ACS Chem. Biol. 2006, 1, 615-618.
    • (2006) ACS Chem. Biol , vol.1 , pp. 615-618
    • Tannenbaum, S.R.1    White, F.M.2
  • 134
    • 24744452818 scopus 로고    scopus 로고
    • The double regulation of endothelial nitric oxide synthase by caveolae and caveolin: A paradox solved through the study of angiogenesis
    • Sbaa, E.; Frerart, F.; Feron, O. The double regulation of endothelial nitric oxide synthase by caveolae and caveolin: A paradox solved through the study of angiogenesis. Trends Cardiovasc. Med. 2005, 15, 157-162.
    • (2005) Trends Cardiovasc. Med , vol.15 , pp. 157-162
    • Sbaa, E.1    Frerart, F.2    Feron, O.3
  • 136
    • 0015440096 scopus 로고
    • Intracellular iron-binding macromolecules in hela cells
    • USA
    • Robbins, E.; Fant, J.; Norton, W. Intracellular iron-binding macromolecules in hela cells. Proc. Natl. Acad. Sci. USA 1972, 69, 3708-3712.
    • (1972) Proc. Natl. Acad. Sci , vol.69 , pp. 3708-3712
    • Robbins, E.1    Fant, J.2    Norton, W.3
  • 137
    • 0017834413 scopus 로고
    • Effects of disulphides and alpha-oxoglutarate on nuclear thiol formation and thiol content of chromatin in lysed rat spleen nuclei
    • Bitny-Szlachto, S.; Ochalska-Czepulis, M. Effects of disulphides and alpha-oxoglutarate on nuclear thiol formation and thiol content of chromatin in lysed rat spleen nuclei. Int. J. Biochem. 1978, 9, 179-183.
    • (1978) Int. J. Biochem , vol.9 , pp. 179-183
    • Bitny-Szlachto, S.1    Ochalska-Czepulis, M.2
  • 138
    • 41149101469 scopus 로고    scopus 로고
    • Interaction of iron ions with oxygen or nitrogen monoxide in chromosomes triggers synchronous expression/suppression oscillations of compact gene groups (Genomewide oscillation): Hypothesis
    • Vanin, A.F.; Ivanov, V.I. Interaction of iron ions with oxygen or nitrogen monoxide in chromosomes triggers synchronous expression/suppression oscillations of compact gene groups (Genomewide oscillation): Hypothesis. Nitric Oxide 2008, 18, 147-152.
    • (2008) Nitric Oxide , vol.18 , pp. 147-152
    • Vanin, A.F.1    Ivanov, V.I.2
  • 140
    • 33750370444 scopus 로고    scopus 로고
    • Microrna signatures in human cancers
    • Calin, G.A.; Croce, C.M. Microrna signatures in human cancers. Nat. Rev. Cancer 2006, 6, 857-866.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 141
    • 34247364093 scopus 로고    scopus 로고
    • Mechanisms of microrna-mediated gene regulation in animal cells
    • Nilsen, T.W. Mechanisms of microrna-mediated gene regulation in animal cells. Trends Genet. 2007, 23, 243-249.
    • (2007) Trends Genet , vol.23 , pp. 243-249
    • Nilsen, T.W.1
  • 144
    • 28944439309 scopus 로고    scopus 로고
    • Animal micrornas confer robustness to gene expression and have a significant impact on 3'utr evolution
    • Stark, A.; Brennecke, J.; Bushati, N.; Russell, R.B.; Cohen, S.M. Animal micrornas confer robustness to gene expression and have a significant impact on 3'utr evolution. Cell 2005, 123, 1133-1146.
    • (2005) Cell , vol.123 , pp. 1133-1146
    • Stark, A.1    Brennecke, J.2    Bushati, N.3    Russell, R.B.4    Cohen, S.M.5
  • 150
  • 152
    • 22244467087 scopus 로고    scopus 로고
    • Microrna-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan, J.A.; Krichevsky, A.M.; Kosik, K.S. Microrna-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 2005, 65, 6029-6033.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 153
    • 0036267029 scopus 로고    scopus 로고
    • Expression of glutathione s-transferase pi in benign mucosa, barrett's metaplasia, and adenocarcinoma of the esophagus
    • Chandra, R.K.; Bentz, B.G.; Haines, G.K., III; Robinson, A.M.; Radosevich, J.A. Expression of glutathione s-transferase pi in benign mucosa, barrett's metaplasia, and adenocarcinoma of the esophagus. Head Neck 2002, 24, 575-581.
    • (2002) Head Neck , vol.24 , pp. 575-581
    • Chandra, R.K.1    Bentz, B.G.2    Haines III, G.K.3    Robinson, A.M.4    Radosevich, J.A.5
  • 157
    • 31944444262 scopus 로고    scopus 로고
    • Mir-155/bic as an oncogenic microrna
    • Tam, W.; Dahlberg, J.E. Mir-155/bic as an oncogenic microrna. Genes Chromos. Cancer 2006, 45, 211-212.
    • (2006) Genes Chromos. Cancer , vol.45 , pp. 211-212
    • Tam, W.1    Dahlberg, J.E.2
  • 158
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microrna-127 with downregulation of the proto-oncogene bcl6 by chromatin-modifying drugs in human cancer cells
    • Saito, Y.; Liang, G.; Egger, G.; Friedman, J.M.; Chuang, J.C.; Coetzee, G.A.; Jones, P.A. Specific activation of microrna-127 with downregulation of the proto-oncogene bcl6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 2006, 9, 435-443.
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3    Friedman, J.M.4    Chuang, J.C.5    Coetzee, G.A.6    Jones, P.A.7
  • 159
    • 33644856123 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer: Past, present and future
    • Yoo, C.B.; Jones, P.A. Epigenetic therapy of cancer: Past, present and future. Nat. Rev. Drug Discov. 2006, 5, 37-50.
    • (2006) Nat. Rev. Drug Discov , vol.5 , pp. 37-50
    • Yoo, C.B.1    Jones, P.A.2
  • 160
    • 77949488939 scopus 로고    scopus 로고
    • Mir-21 is induced in endothelial cells by shear stress and modulates apoptosis and enos activity
    • Weber, M.; Baker, M.B.; Moore, J.P.; Searles, C.D. Mir-21 is induced in endothelial cells by shear stress and modulates apoptosis and enos activity. Biochem. Biophys. Res. Commun. 2010, 393, 643-648.
    • (2010) Biochem. Biophys. Res. Commun , vol.393 , pp. 643-648
    • Weber, M.1    Baker, M.B.2    Moore, J.P.3    Searles, C.D.4
  • 161
    • 34250172419 scopus 로고    scopus 로고
    • Microrna expression signature and antisense-mediated depletion reveal an essential role of microrna in vascular neointimal lesion formation
    • Ji, R.; Cheng, Y.; Yue, J.; Yang, J.; Liu, X.; Chen, H.; Dean, D.B.; Zhang, C. Microrna expression signature and antisense-mediated depletion reveal an essential role of microrna in vascular neointimal lesion formation. Circ. Res. 2007, 100, 1579-1588.
    • (2007) Circ. Res , vol.100 , pp. 1579-1588
    • Ji, R.1    Cheng, Y.2    Yue, J.3    Yang, J.4    Liu, X.5    Chen, H.6    Dean, D.B.7    Zhang, C.8
  • 163
    • 58649107855 scopus 로고    scopus 로고
    • Microrna and cancer--focus on apoptosis
    • Wang, Y.; Lee, C.G. Microrna and cancer--focus on apoptosis. J. Cell Mol. Med. 2009, 13, 12-23.
    • (2009) J. Cell Mol. Med , vol.13 , pp. 12-23
    • Wang, Y.1    Lee, C.G.2
  • 164
    • 70449584568 scopus 로고    scopus 로고
    • Mir-145 directs intestinal maturation in zebrafish
    • USA
    • Zeng, L.; Carter, A.D.; Childs, S.J. Mir-145 directs intestinal maturation in zebrafish. Proc. Natl. Acad. Sci. USA 2009, 106, 17793-17798.
    • (2009) Proc. Natl. Acad. Sci , vol.106 , pp. 17793-17798
    • Zeng, L.1    Carter, A.D.2    Childs, S.J.3
  • 165
    • 70350455091 scopus 로고    scopus 로고
    • Inducible nitric-oxide synthase expression is regulated by mitogen-activated protein kinase phosphatase-1
    • Wang, X.; Zhao, Q.; Matta, R.; Meng, X.; Liu, X.; Liu, C.G.; Nelin, L.D.; Liu, Y. Inducible nitric-oxide synthase expression is regulated by mitogen-activated protein kinase phosphatase-1. J. Biol. Chem. 2009, 284, 27123-27134.
    • (2009) J. Biol. Chem , vol.284 , pp. 27123-27134
    • Wang, X.1    Zhao, Q.2    Matta, R.3    Meng, X.4    Liu, X.5    Liu, C.G.6    Nelin, L.D.7    Liu, Y.8
  • 166
    • 77951215073 scopus 로고    scopus 로고
    • Stimulation of inducible nitric oxide by hepatitis b virus transactivator protein hbx requires mta1 coregulator
    • Bui-Nguyen, T.M.; Pakala, S.B.; Sirigiri, D.R.; Martin, E.; Murad, F.; Kumar, R. Stimulation of inducible nitric oxide by hepatitis b virus transactivator protein hbx requires mta1 coregulator. J. Biol. Chem. 2010, 285, 6980-6986.
    • (2010) J. Biol. Chem , vol.285 , pp. 6980-6986
    • Bui-Nguyen, T.M.1    Pakala, S.B.2    Sirigiri, D.R.3    Martin, E.4    Murad, F.5    Kumar, R.6
  • 168
    • 24744438447 scopus 로고    scopus 로고
    • Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells
    • Chan, G.C.; Fish, J.E.; Mawji, I.A.; Leung, D.D.; Rachlis, A.C.; Marsden, P.A. Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells. J. Immunol. 2005, 175, 3846-3861.
    • (2005) J. Immunol , vol.175 , pp. 3846-3861
    • Chan, G.C.1    Fish, J.E.2    Mawji, I.A.3    Leung, D.D.4    Rachlis, A.C.5    Marsden, P.A.6
  • 169
    • 33847047461 scopus 로고    scopus 로고
    • Epigenetics: A landscape takes shape
    • Goldberg, A.D.; Allis, C.D.; Bernstein, E. Epigenetics: A landscape takes shape. Cell 2007, 128, 635-638.
    • (2007) Cell , vol.128 , pp. 635-638
    • Goldberg, A.D.1    Allis, C.D.2    Bernstein, E.3
  • 170
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides, T. Chromatin modifications and their function. Cell 2007, 128, 693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 172
    • 39749127166 scopus 로고    scopus 로고
    • The rpd3/hda1 family of lysine deacetylases: From bacteria and yeast to mice and men
    • Yang, X.J.; Seto, E. The rpd3/hda1 family of lysine deacetylases: From bacteria and yeast to mice and men. Nat. Rev. Mol. Cell Biol. 2008, 9, 206-218.
    • (2008) Nat. Rev. Mol. Cell Biol , vol.9 , pp. 206-218
    • Yang, X.J.1    Seto, E.2
  • 173
    • 53649086367 scopus 로고    scopus 로고
    • Mechanisms and molecular probes of sirtuins
    • Smith, B.C.; Hallows, W.C.; Denu, J.M. Mechanisms and molecular probes of sirtuins. Chem. Biol. 2008, 15, 1002-1013.
    • (2008) Chem. Biol , vol.15 , pp. 1002-1013
    • Smith, B.C.1    Hallows, W.C.2    Denu, J.M.3
  • 174
    • 34548526743 scopus 로고    scopus 로고
    • Chromatin remodeling and cancer, part I: Covalent histone modifications
    • Wang, G.G.; Allis, C.D.; Chi, P. Chromatin remodeling and cancer, part I: Covalent histone modifications. Trends Mol. Med. 2007, 13, 363-372.
    • (2007) Trends Mol. Med , vol.13 , pp. 363-372
    • Wang, G.G.1    Allis, C.D.2    Chi, P.3
  • 175
    • 13844252820 scopus 로고    scopus 로고
    • Regulation of histone deacetylase activities
    • Sengupta, N.; Seto, E. Regulation of histone deacetylase activities. J. Cell Biochem. 2004, 93, 57-67.
    • (2004) J. Cell Biochem , vol.93 , pp. 57-67
    • Sengupta, N.1    Seto, E.2
  • 176
    • 0027104253 scopus 로고
    • Biochemistry of nitric oxide and its redox-activated forms
    • Stamler, J.S.; Singel, D.J.; Loscalzo, J. Biochemistry of nitric oxide and its redox-activated forms. Science 1992, 258, 1898-1902.
    • (1992) Science , vol.258 , pp. 1898-1902
    • Stamler, J.S.1    Singel, D.J.2    Loscalzo, J.3
  • 177
    • 16244366803 scopus 로고    scopus 로고
    • Class ii histone deacetylases: From sequence to function, regulation, and clinical implication
    • Yang, X.J.; Gregoire, S. Class ii histone deacetylases: From sequence to function, regulation, and clinical implication. Mol. Cell Biol. 2005, 25, 2873-2884.
    • (2005) Mol. Cell Biol , vol.25 , pp. 2873-2884
    • Yang, X.J.1    Gregoire, S.2
  • 178
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the pgc-1 family of transcription coactivators
    • Lin, J.; Handschin, C.; Spiegelman, B.M. Metabolic control through the pgc-1 family of transcription coactivators. Cell Metab. 2005, 1, 361-370.
    • (2005) Cell Metab , vol.1 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 179
    • 0036753290 scopus 로고    scopus 로고
    • DNA methylation: A profile of methods and applications
    • Fraga, M.F.; Esteller, M. DNA methylation: A profile of methods and applications. BioTechniques 2002, 33, 632, 634, 636-649.
    • (2002) BioTechniques , vol.33
    • Fraga, M.F.1    Esteller, M.2
  • 180
    • 0033564902 scopus 로고    scopus 로고
    • DNA methylation
    • Singal, R.; Ginder, G.D. DNA methylation. Blood 1999, 93, 4059-4070.
    • (1999) Blood , vol.93 , pp. 4059-4070
    • Singal, R.1    Ginder, G.D.2
  • 181
    • 77954061853 scopus 로고    scopus 로고
    • Enzymatic approaches and bisulfite sequencing cannot distinguish between 5- methylcytosine and 5-hydroxymethylcytosine in DNA
    • Nestor, C. Enzymatic approaches and bisulfite sequencing cannot distinguish between 5- methylcytosine and 5-hydroxymethylcytosine in DNA. BioTechniques 2010, 48, 317-319.
    • (2010) BioTechniques , vol.48 , pp. 317-319
    • Nestor, C.1
  • 183
    • 0034642777 scopus 로고    scopus 로고
    • Targeting of human enos promoter to the hprt locus of mice leads to tissue-restricted transgene expression
    • Guillot, P.V.; Liu, L.; Kuivenhoven, J.A.; Guan, J.; Rosenberg, R.D.; Aird, W.C. Targeting of human enos promoter to the hprt locus of mice leads to tissue-restricted transgene expression. Physiol. Genomics 2000, 2, 77-83.
    • (2000) Physiol. Genomics , vol.2 , pp. 77-83
    • Guillot, P.V.1    Liu, L.2    Kuivenhoven, J.A.3    Guan, J.4    Rosenberg, R.D.5    Aird, W.C.6
  • 185
    • 13644268928 scopus 로고    scopus 로고
    • Nitrosative stress induces DNA strand breaks but not caspase mediated apoptosis in a lung cancer cell line
    • Bentz, B.G.; Hammer, N.D.; Radosevich, J.A.; Haines, G.K., III Nitrosative stress induces DNA strand breaks but not caspase mediated apoptosis in a lung cancer cell line. J. Carcinog. 2004, 3, 16.
    • (2004) J. Carcinog , vol.3 , pp. 16
    • Bentz, B.G.1    Hammer, N.D.2    Radosevich, J.A.3    Haines III, G.K.4
  • 186
    • 77955073133 scopus 로고    scopus 로고
    • Long-term adaptation of lung tumor cell lines with increasing concentrations of nitric oxide donor
    • Radosevich, J.A.; Elseth, K.M.; Vesper, B.J.; Tarjan, G.; Haines, G.K., III Long-term adaptation of lung tumor cell lines with increasing concentrations of nitric oxide donor. Open Lung Cancer J. 2009, 2, 35-44.
    • (2009) Open Lung Cancer J , vol.2 , pp. 35-44
    • Radosevich, J.A.1    Elseth, K.M.2    Vesper, B.J.3    Tarjan, G.4    Haines III, G.K.5
  • 187
    • 77954637770 scopus 로고    scopus 로고
    • Long-term adaptation of breast tumor cell lines to high concentrations of nitric oxide
    • Vesper, B.J.; Elseth, K.M.; Tarjan, G.; Haines, G.K., III; Radosevich, J.A. Long-term adaptation of breast tumor cell lines to high concentrations of nitric oxide. Tumor. Biol. 2010, 31, 267-275.
    • (2010) Tumor. Biol , vol.31 , pp. 267-275
    • Vesper, B.J.1    Elseth, K.M.2    Tarjan, G.3    Haines III, G.K.4    Radosevich, J.A.5
  • 189
    • 0032171420 scopus 로고    scopus 로고
    • Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide
    • Wink, D.A.; Mitchell, J.B. Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide. Free Radic. Biol. Med. 1998, 25, 434-456.
    • (1998) Free Radic. Biol. Med , vol.25 , pp. 434-456
    • Wink, D.A.1    Mitchell, J.B.2
  • 190
    • 74049140048 scopus 로고    scopus 로고
    • Inflammation and cancer: Interweaving microrna, free radical, cytokine and p53 pathways
    • Schetter, A.J.; Heegaard, N.H.; Harris, C.C. Inflammation and cancer: Interweaving microrna, free radical, cytokine and p53 pathways. Carcinogenesis 2010, 31, 37-49.
    • (2010) Carcinogenesis , vol.31 , pp. 37-49
    • Schetter, A.J.1    Heegaard, N.H.2    Harris, C.C.3


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