-
1
-
-
0030846212
-
Alterations in DNA methylation: A fundamental aspect of neoplasia
-
Baylin SB, Herman JG, Graff JR, Vertino PM, Issa JP (1998) Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv Cancer Res 72: 141-196
-
(1998)
Adv Cancer Res
, vol.72
, pp. 141-196
-
-
Baylin, S.B.1
Herman, J.G.2
Graff, J.R.3
Vertino, P.M.4
Issa, J.P.5
-
2
-
-
0028307844
-
Molecular analysis of genomic abnormalities in human gliomas
-
Bello MJ, de Campos JM, Kusak ME, Vaquero J, Sarasa JL, Pestaña A, Rey JA (1994) Molecular analysis of genomic abnormalities in human gliomas. Cancer Genet Cytogenet 73: 122-129
-
(1994)
Cancer Genet Cytogenet
, vol.73
, pp. 122-129
-
-
Bello, M.J.1
De Campos, J.M.2
Kusak, M.E.3
Vaquero, J.4
Sarasa, J.L.5
Pestaña, A.6
Rey, J.A.7
-
3
-
-
0025059545
-
Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma
-
Bookstein R, Rio P, Madrepeira SA, Homg F, Allred C, Grizzle WE, Lee WH (1990a) Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma. Proc Natl Acad Sci USA 87: 7762-7766
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 7762-7766
-
-
Bookstein, R.1
Rio, P.2
Madrepeira, S.A.3
Homg, F.4
Allred, C.5
Grizzle, W.E.6
Lee, W.H.7
-
4
-
-
0025068887
-
Supression of tumourigenicity of human prostate carcinoma cells by replacing a mutated RB1 gene
-
Bookstein R, Shew J-Y, Chen P-L, Scully P, Lee W-H (1990b) Supression of tumourigenicity of human prostate carcinoma cells by replacing a mutated RB1 gene. Science 247: 712-715
-
(1990)
Science
, vol.247
, pp. 712-715
-
-
Bookstein, R.1
Shew, J.-Y.2
Chen, P.-L.3
Scully, P.4
Lee, W.-H.5
-
5
-
-
0026729463
-
The retinoblastoma gene in breast cancer: Allelic loss is not correlated with loss of gene protein expression
-
Borg A, Zhang QX, Alm P, Olsson H, Sellberg G (1992) The retinoblastoma gene in breast cancer: allelic loss is not correlated with loss of gene protein expression. Cancer Res 52: 2991-2994
-
(1992)
Cancer Res
, vol.52
, pp. 2991-2994
-
-
Borg, A.1
Zhang, Q.X.2
Alm, P.3
Olsson, H.4
Sellberg, G.5
-
6
-
-
0024439444
-
The retinoblastoma gene is phosphorylated during specific phases of the cell cycle
-
Buchkovich K, Duffy LA, Harlow E (1989) The retinoblastoma gene is phosphorylated during specific phases of the cell cycle. Cell 58: 1097-1105
-
(1989)
Cell
, vol.58
, pp. 1097-1105
-
-
Buchkovich, K.1
Duffy, L.A.2
Harlow, E.3
-
7
-
-
0031906358
-
Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas
-
Burns KL, Ueki K, Jhung SL, Koh J, Louis DN (1998) Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas. J Neuropathol Exp Neurol 57: 122-130
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 122-130
-
-
Burns, K.L.1
Ueki, K.2
Jhung, S.L.3
Koh, J.4
Louis, D.N.5
-
8
-
-
0025051384
-
Altered expression of the retinoblastoma gene product in human sarcomas
-
Cance WG, Brennan MF, Dudas ME, Huang CM, Cordon-Cardo C (1990) Altered expression of the retinoblastoma gene product in human sarcomas. N Engl J Med 323: 1457-1462
-
(1990)
N Engl J Med
, vol.323
, pp. 1457-1462
-
-
Cance, W.G.1
Brennan, M.F.2
Dudas, M.E.3
Huang, C.M.4
Cordon-Cardo, C.5
-
9
-
-
0030042776
-
Distinct regions of allelic loss on 13q in prostate cancer
-
Cooney KA, Wetzel JC, Merajver SD, Macoska JA, Singleton TP, Wojno KJ (1996) Distinct regions of allelic loss on 13q in prostate cancer. Cancer Res 56: 1142-1145
-
(1996)
Cancer Res
, vol.56
, pp. 1142-1145
-
-
Cooney, K.A.1
Wetzel, J.C.2
Merajver, S.D.3
Macoska, J.A.4
Singleton, T.P.5
Wojno, K.J.6
-
10
-
-
0028204821
-
Loss of retinoblastoma tumour-suppressor gene in parathyroid carcinoma
-
Cryns VL, Thor A, Xu HJ, Hu SX, Wierman ME, Vickery AL, Benedict WF, Arnold A (1994) Loss of retinoblastoma tumour-suppressor gene in parathyroid carcinoma. N Engl J Med 330: 757-761
-
(1994)
N Engl J Med
, vol.330
, pp. 757-761
-
-
Cryns, V.L.1
Thor, A.2
Xu, H.J.3
Hu, S.X.4
Wierman, M.E.5
Vickery, A.L.6
Benedict, W.F.7
Arnold, A.8
-
11
-
-
2642647114
-
Initiation of DNA replication at CpG islands in mammalian chromosomes
-
Delgado S, Gomez M, Bird A, Antequera F (1998) Initiation of DNA replication at CpG islands in mammalian chromosomes. EMBO J 17: 2426-2435
-
(1998)
EMBO J
, vol.17
, pp. 2426-2435
-
-
Delgado, S.1
Gomez, M.2
Bird, A.3
Antequera, F.4
-
12
-
-
0034925182
-
Concurrent hypermethylation of multiple genes is associated with grade of oligodendroglial tumours
-
Dong S-M, Pang JC-S, Poon W-S, Hu J, Yo K-F, Chang AR, Ng H-K (2001) Concurrent hypermethylation of multiple genes is associated with grade of oligodendroglial tumours. J Neuropathol Exp Neurol 60: 808-816
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 808-816
-
-
Dong, S.-M.1
Pang, J.C.-S.2
Poon, W.-S.3
Hu, J.4
Yo, K.-F.5
Chang, A.R.6
Ng, H.-K.7
-
13
-
-
0036145156
-
Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours
-
Esteller M, Herman JG (2002) Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours. J Pathol 196: 1-7
-
(2002)
J Pathol
, vol.196
, pp. 1-7
-
-
Esteller, M.1
Herman, J.G.2
-
14
-
-
0022506980
-
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
-
Friend SH, Bernards R, Rogelji S, Weinberg RA, Rapaport JM, Alberts DM, Dryja TP (1986) A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323: 643-646
-
(1986)
Nature
, vol.323
, pp. 643-646
-
-
Friend, S.H.1
Bernards, R.2
Rogelji, S.3
Weinberg, R.A.4
Rapaport, J.M.5
Alberts, D.M.6
Dryja, T.P.7
-
15
-
-
0027956684
-
Loss of heterozygosity at the RB locus correlates with loss of RB protein in primary malignant neuroendocrine lung carcinoma
-
Gouyer V, Gazzeri S, Brambilla E, Bolon I, Moro D, Perron P, Benabid AL, Brambilla C (1994) Loss of heterozygosity at the RB locus correlates with loss of RB protein in primary malignant neuroendocrine lung carcinoma. Int J Cancer 58: 818-824
-
(1994)
Int J Cancer
, vol.58
, pp. 818-824
-
-
Gouyer, V.1
Gazzeri, S.2
Brambilla, E.3
Bolon, I.4
Moro, D.5
Perron, P.6
Benabid, A.L.7
Brambilla, C.8
-
16
-
-
0027962591
-
Frequency and parental origin of hypermethylated RB1 alleles in retinoblastoma
-
Greger V, Debus N, Lohmann D, Hopping W, Passarge E, Horsthemke B (1994) Frequency and parental origin of hypermethylated RB1 alleles in retinoblastoma. Hum Genet 94: 491-496
-
(1994)
Hum Genet
, vol.94
, pp. 491-496
-
-
Greger, V.1
Debus, N.2
Lohmann, D.3
Hopping, W.4
Passarge, E.5
Horsthemke, B.6
-
17
-
-
0025311341
-
Altered structure and expression of the human retinoblastoma susceptibility gene in small cell lung cancer
-
Hensel CH, Hsieh C-L, Gazdar AF, Johnson BE, Sakaguchi AY, Naylor SL, Lee W-H, Lee EY-HP (1990) Altered structure and expression of the human retinoblastoma susceptibility gene in small cell lung cancer. Cancer Res 50: 3067-3072
-
(1990)
Cancer Res
, vol.50
, pp. 3067-3072
-
-
Hensel, C.H.1
Hsieh, C.-L.2
Gazdar, A.F.3
Johnson, B.E.4
Sakaguchi, A.Y.5
Naylor, S.L.6
Lee, W.-H.7
Lee, E.Y.-H.P.8
-
18
-
-
0027943938
-
The retinoblastoma gene is involved in malignant progression of astrocytomas
-
Henson JW, Schnitker BL, Correa KM, von Deimling A, Fassbender F, Xu H-J, Benedict WF, Yandell DW, Louis DN (1994) The retinoblastoma gene is involved in malignant progression of astrocytomas. Ann Neurol 36: 714-721
-
(1994)
Ann Neurol
, vol.36
, pp. 714-721
-
-
Henson, J.W.1
Schnitker, B.L.2
Correa, K.M.3
Von Deimling, A.4
Fassbender, F.5
Xu, H.-J.6
Benedict, W.F.7
Yandell, D.W.8
Louis, D.N.9
-
19
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB (1996) Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 93: 9821-9826
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
20
-
-
0027297105
-
Molecular mechanisms of oncogenetic mutations in tumours from patients with bilateral and unilateral retinoblastoma
-
Hogg A, Bia B, Onadim Z, Cowell K (1993) Molecular mechanisms of oncogenetic mutations in tumours from patients with bilateral and unilateral retinoblastoma. Proc Natl Acad Sci USA 90: 7351-7355
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 7351-7355
-
-
Hogg, A.1
Bia, B.2
Onadim, Z.3
Cowell, K.4
-
22
-
-
0025988149
-
Inactivation of the retinoblastoma gene in human bladder and renal cell carcinomas
-
Ishikawa J, Xu H-J, Yandell DW, Maeda S, Kamidono S, Benedict WF, Takahashi R (1991) Inactivation of the retinoblastoma gene in human bladder and renal cell carcinomas. Cancer Res 51: 5736-5743
-
(1991)
Cancer Res
, vol.51
, pp. 5736-5743
-
-
Ishikawa, J.1
Xu, H.-J.2
Yandell, D.W.3
Maeda, S.4
Kamidono, S.5
Benedict, W.F.6
Takahashi, R.7
-
23
-
-
0029898837
-
DNA methylation errors and cancer
-
Jones PA (1996) DNA methylation errors and cancer. Cancer Res 56: q2463-2467
-
(1996)
Cancer Res
, vol.56
-
-
Jones, P.A.1
-
24
-
-
0032960181
-
Cancer epigenetic comes of age
-
Jones PA, Laird PW (1999) Cancer epigenetic comes of age. Nat Genet 21: 163-167
-
(1999)
Nat Genet
, vol.21
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
26
-
-
0023261635
-
The retinoblastoma susceptibility gene product is a nuclear phosphoprotein associated with DNA binding activity
-
Lee WH, Shew JY, Hong F, Sery T, Donoso LA, Young LJ, Bookstein R, Lee EYHP (1987) The retinoblastoma susceptibility gene product is a nuclear phosphoprotein associated with DNA binding activity. Nature 329: 642-645
-
(1987)
Nature
, vol.329
, pp. 642-645
-
-
Lee, W.H.1
Shew, J.Y.2
Hong, F.3
Sery, T.4
Donoso, L.A.5
Young, L.J.6
Bookstein, R.7
Lee, E.Y.H.P.8
-
27
-
-
0026673062
-
Altered expression of retinoblastoma protein and known prognostic variables in locally advanced bladder cancer
-
Logothetis CJ, Xu HJ, Ro JY, Xu SX, Sahin A, Ordonez N, Benedict WF (1992) Altered expression of retinoblastoma protein and known prognostic variables in locally advanced bladder cancer. J Natl Cancer Inst 84: 1256-1261
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 1256-1261
-
-
Logothetis, C.J.1
Xu, H.J.2
Ro, J.Y.3
Xu, S.X.4
Sahin, A.5
Ordonez, N.6
Benedict, W.F.7
-
29
-
-
0025223332
-
Variable mutation of the RB gene in small-cell lung carcinoma
-
Mori N, Yokota J, Akiyama T, Sameshima Y, Okamoto A, Mizoguchi H, Toyoshima K, Sugimura T, Terada M (1990) Variable mutation of the RB gene in small-cell lung carcinoma. Oncogene 11: 1713-1717
-
(1990)
Oncogene
, vol.11
, pp. 1713-1717
-
-
Mori, N.1
Yokota, J.2
Akiyama, T.3
Sameshima, Y.4
Okamoto, A.5
Mizoguchi, H.6
Toyoshima, K.7
Sugimura, T.8
Terada, M.9
-
30
-
-
0029916697
-
Immunohistochemical detection of CDKN2, retinoblastoma and p53 gene products in primary astrocytic tumours
-
Nakamura M, Konishi N, Hiasa Y, Tsunoda S, Fukushima Y, Tsuzuki T, Takemura K, Aoki H, Kobitsu K, Sakaki Y (1996) Immunohistochemical detection of CDKN2, retinoblastoma and p53 gene products in primary astrocytic tumours. Int J Oncol 8: 889-893
-
(1996)
Int J Oncol
, vol.8
, pp. 889-893
-
-
Nakamura, M.1
Konishi, N.2
Hiasa, Y.3
Tsunoda, S.4
Fukushima, Y.5
Tsuzuki, T.6
Takemura, K.7
Aoki, H.8
Kobitsu, K.9
Sakaki, Y.10
-
32
-
-
0027537296
-
CpG methylation inactivates the promoter activity of the human retinoblastoma tumour-suppressor gene
-
Ohtani-Fujita N, Fujita T, Aoike A, Osifchin NE, Robbins PD, Sakai T (1993) CpG methylation inactivates the promoter activity of the human retinoblastoma tumour-suppressor gene. Oncogene 8: 1063-1067
-
(1993)
Oncogene
, vol.8
, pp. 1063-1067
-
-
Ohtani-Fujita, N.1
Fujita, T.2
Aoike, A.3
Osifchin, N.E.4
Robbins, P.D.5
Sakai, T.6
-
33
-
-
0026627772
-
Loss of heterozygosity for distal markers on 22q in human gliomas
-
Rey JA, Bello MJ, Jimenez-Lara A, Vaquero J, Kusak ME, de Campos JM, Sarasa JL, Pestaña A (1992) Loss of heterozygosity for distal markers on 22q in human gliomas. Int J Cancer 51: 703-706
-
(1992)
Int J Cancer
, vol.51
, pp. 703-706
-
-
Rey, J.A.1
Bello, M.J.2
Jimenez-Lara, A.3
Vaquero, J.4
Kusak, M.E.5
De Campos, J.M.6
Sarasa, J.L.7
Pestaña, A.8
-
34
-
-
0025900744
-
Oncogenic germ-line mutations in SpI and ATF sites in the human retinoblastoma gene
-
Sakai T, Ohtami N, McGee TL, Robbins PD, Dryja TP (1991) Oncogenic germ-line mutations in SpI and ATF sites in the human retinoblastoma gene. Nature 353: 83-86
-
(1991)
Nature
, vol.353
, pp. 83-86
-
-
Sakai, T.1
Ohtami, N.2
McGee, T.L.3
Robbins, P.D.4
Dryja, T.P.5
-
35
-
-
0033626213
-
INK4 gene inactivation by hypermethylaton in lung cancer during the process of metastasis and its relation to the status of p53
-
INK4 gene inactivation by hypermethylaton in lung cancer during the process of metastasis and its relation to the status of p53. Clin Cancer Res 6: 4307-4313
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4307-4313
-
-
Seike, M.1
Gemma, A.2
Hosoya, Y.3
Hemmi, S.4
Taniguchi, Y.5
Fukuda, Y.6
Yamanaka, N.7
Kudoh, S.8
-
36
-
-
0033119604
-
Chromosome 13q deletion mapping in pituitary tumours: Infrequent loss of the retinoblastoma susceptibility gene (RB1) locus despite loss of RB1 protein product in somatotrophinomas
-
Simpson DJ, Magnay J, Bicknell JE, Barkan AL, McNicol AM, Clayton RN, Farrell WE (1999) Chromosome 13q deletion mapping in pituitary tumours: infrequent loss of the retinoblastoma susceptibility gene (RB1) locus despite loss of RB1 protein product in somatotrophinomas. Cancer Res 59: 2703-2709
-
(1999)
Cancer Res
, vol.59
, pp. 2703-2709
-
-
Simpson, D.J.1
Magnay, J.2
Bicknell, J.E.3
Barkan, A.L.4
McNicol, A.M.5
Clayton, R.N.6
Farrell, W.E.7
-
37
-
-
0034161905
-
Loss of pRb expression in pituitary adenomas is associated with methylation of the RB1 CpG island
-
Simpson DJ, Hibberts NA, McNicol AM, Clayton RN, Farrell WE (2000) Loss of pRb expression in pituitary adenomas is associated with methylation of the RB1 CpG island. Cancer Res 60: 1211-1216
-
(2000)
Cancer Res
, vol.60
, pp. 1211-1216
-
-
Simpson, D.J.1
Hibberts, N.A.2
McNicol, A.M.3
Clayton, R.N.4
Farrell, W.E.5
-
38
-
-
0030925099
-
Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumours
-
Stirzaker C, Millar S, Paul CL, Warnecke PM, Harrison J, Vincent PC, Frommer M, Clark SJ (1997) Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumours. Cancer Res 57: 2229-2237
-
(1997)
Cancer Res
, vol.57
, pp. 2229-2237
-
-
Stirzaker, C.1
Millar, S.2
Paul, C.L.3
Warnecke, P.M.4
Harrison, J.5
Vincent, P.C.6
Frommer, M.7
Clark, S.J.8
-
39
-
-
0027078657
-
Retinoblastoma and p53 gene product expression in breast carcinoma: Immunohistochemical analysis and clinicopathologic correlation
-
Trudel M, Mulligna L, Cavenee W, Margolese R, Cote J, Gariepy G (1992) Retinoblastoma and p53 gene product expression in breast carcinoma: immunohistochemical analysis and clinicopathologic correlation. Hum Pathol 23: 1388-1394
-
(1992)
Hum Pathol
, vol.23
, pp. 1388-1394
-
-
Trudel, M.1
Mulligna, L.2
Cavenee, W.3
Margolese, R.4
Cote, J.5
Gariepy, G.6
-
40
-
-
0030056824
-
Alterations of retinoblastoma, p53, p16(CDKN2), and p15 genes in human astrocytomas
-
Tsuzuki T, Tsunoda S, Sakaki T, Konishi N, Hiasa Y, Nakamura M (1996) Alterations of retinoblastoma, p53, p16(CDKN2), and p15 genes in human astrocytomas. Cancer 78: 287-293
-
(1996)
Cancer
, vol.78
, pp. 287-293
-
-
Tsuzuki, T.1
Tsunoda, S.2
Sakaki, T.3
Konishi, N.4
Hiasa, Y.5
Nakamura, M.6
-
41
-
-
0030070484
-
CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated
-
Ueki K, Ono Y, Henson JW, Efird JT, von Deimling A, Louis DN (1996) CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Res 56: 150-153
-
(1996)
Cancer Res
, vol.56
, pp. 150-153
-
-
Ueki, K.1
Ono, Y.2
Henson, J.W.3
Efird, J.T.4
Von Deimling, A.5
Louis, D.N.6
-
42
-
-
0035213384
-
Concurrent inactivation of RB1 and TP53 pathways in anaplastic oligodendrogliomas
-
Watanabe T, Yokoo H, Yokoo M, Yonekawa Y, Kleihues P, Ohgaki H (2001) Concurrent inactivation of RB1 and TP53 pathways in anaplastic oligodendrogliomas. J Neuropathol Exp Neurol 60: 1181-1189
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 1181-1189
-
-
Watanabe, T.1
Yokoo, H.2
Yokoo, M.3
Yonekawa, Y.4
Kleihues, P.5
Ohgaki, H.6
-
43
-
-
0025899109
-
Absence of retinoblastoma protein expression in primary non-small cell lung carcinomas
-
Xu HJ, Xu SX, Cagle PT, Moore GE, Benedict WF (1991) Absence of retinoblastoma protein expression in primary non-small cell lung carcinomas. Cancer Res 51: 2735-2739
-
(1991)
Cancer Res
, vol.51
, pp. 2735-2739
-
-
Xu, H.J.1
Xu, S.X.2
Cagle, P.T.3
Moore, G.E.4
Benedict, W.F.5
-
44
-
-
0027516618
-
Loss of RB protein expression in primary bladder cancer correlates with loss of heterozygosity at the RB locus and tumour progression
-
Xu HJ, Cairns P, Hu SX, Knowles MA, Benedict WF (1993) Loss of RB protein expression in primary bladder cancer correlates with loss of heterozygosity at the RB locus and tumour progression. Int J Cancer 53: 781-784
-
(1993)
Int J Cancer
, vol.53
, pp. 781-784
-
-
Xu, H.J.1
Cairns, P.2
Hu, S.X.3
Knowles, M.A.4
Benedict, W.F.5
-
45
-
-
0024835010
-
Oncogeneic point mutations in the human retinoblastoma gene: Their application to genetic counselling
-
Yandell DW, Campbell TA, Dayton SH, Petersen R, Walton D, Little JB, McConkie-Rosell A, Buckley EG, Dryja TP (1989) Oncogeneic point mutations in the human retinoblastoma gene: their application to genetic counselling. N Engl J Med 21: 1689-1695
-
(1989)
N Engl J Med
, vol.21
, pp. 1689-1695
-
-
Yandell, D.W.1
Campbell, T.A.2
Dayton, S.H.3
Petersen, R.4
Walton, D.5
Little, J.B.6
McConkie-Rosell, A.7
Buckley, E.G.8
Dryja, T.P.9
|