Targeting of human eNOS promoter to the Hprt locus of mice leads to tissue-restricted transgene expression

Physiological Genomics

Volumn 2000, Issue 2, 2000, Pages 77-83

  Guillot, Pascale V ^a   Liu, Lixin ^a   Kuivenhoven, Jan Albert ^b   Guan, Jason ^a   Rosenberg, Robert D ^c   Aird, William C ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Endothelial cells; Endothelial nitric oxide synthase; Gene expression; Hypoxanthine phosphoribosyltransferase; Transgenic mice

Indexed keywords

MUS MUSCULUS;

BETA GALACTOSIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; NOS3 PROTEIN, HUMAN; NOS3 PROTEIN, MOUSE;

ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; BIOSYNTHESIS; BLOOD VESSEL; CELL CLONE; CYTOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENE TARGETING; GENETICS; HEART; HEART MUSCLE; HUMAN; MALE; METABOLISM; MOUSE; NEWBORN; PRENATAL DEVELOPMENT; PROMOTER REGION; REPORTER GENE; STEM CELL; TRANSGENE; TRANSGENIC MOUSE; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

ANIMALS; ANIMALS, NEWBORN; BETA-GALACTOSIDASE; BLOOD VESSELS; CLONE CELLS; ENDOTHELIUM, VASCULAR; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENE TARGETING; GENES, REPORTER; HEART; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MALE; MICE; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; MYOCARDIUM; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; ORGAN SPECIFICITY; PROMOTER REGIONS (GENETICS); STEM CELLS; TRANSGENES;

EID: 0034642777     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.2000.2.2.77     Document Type: Article

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