-
1
-
-
0035839058
-
Genes, genetics, and epigenetics: A correspondence
-
Wu C, Morris JR: Genes, genetics, and epigenetics: a correspondence. Science 293(5532), 1103-1105 (2001).
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1103-1105
-
-
Wu, C.1
Morris, J.R.2
-
2
-
-
34249279527
-
Stability and flexibility of epigenetic gene regulation in mammalian development
-
Reik W: Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447(7143), 425-432 (2007).
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 425-432
-
-
Reik, W.1
-
3
-
-
34848911647
-
DNA methylation: The nuts and bolts of repression
-
Miranda TB, Jones PA: DNA methylation: the nuts and bolts of repression. J. Cell. Physiol. 213(2), 384-390 (2007).
-
(2007)
J. Cell. Physiol.
, vol.213
, Issue.2
, pp. 384-390
-
-
Miranda, T.B.1
Jones, P.A.2
-
4
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E: DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99(3), 247-257 (1999).
-
(1999)
Cell
, vol.99
, Issue.3
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
5
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R: Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69(6), 915-926 (1992).
-
(1992)
Cell
, vol.69
, Issue.6
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
6
-
-
0026439115
-
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
-
Leonhardt H, Page AW, Weier HU, Bestor TH: A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 71(5), 865-873 (1992).
-
(1992)
Cell
, vol.71
, Issue.5
, pp. 865-873
-
-
Leonhardt, H.1
Page, A.W.2
Weier, H.U.3
Bestor, T.H.4
-
7
-
-
0032519312
-
Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci
-
Liu Y, Oakeley EJ, Sun L, Jost JP: Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci. Nucleic Acids Res. 26(4), 1038-1045 (1998).
-
(1998)
Nucleic Acids Res.
, vol.26
, Issue.4
, pp. 1038-1045
-
-
Liu, Y.1
Oakeley, E.J.2
Sun, L.3
Jost, J.P.4
-
8
-
-
0036683055
-
Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases
-
Kim GD, Ni J, Kelesoglu N, Roberts RJ, Pradhan S: Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases. EMBO J. 21(15), 4183-4195 (2002).
-
(2002)
EMBO J.
, vol.21
, Issue.15
, pp. 4183-4195
-
-
Kim, G.D.1
Ni, J.2
Kelesoglu, N.3
Roberts, R.J.4
Pradhan, S.5
-
9
-
-
0042132027
-
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
-
Chen T, Ueda Y, Dodge JE, Wang Z, Li E: Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol. Cell. Biol. 23(16), 5594-5605 (2003).
-
(2003)
Mol. Cell. Biol.
, vol.23
, Issue.16
, pp. 5594-5605
-
-
Chen, T.1
Ueda, Y.2
Dodge, J.E.3
Wang, Z.4
Li, E.5
-
10
-
-
4644221440
-
Preference of DNA methyltransferases for CpG islands in mouse embryonic stem cells
-
Hattori N, Abe T, Suzuki M, et al.: Preference of DNA methyltransferases for CpG islands in mouse embryonic stem cells. Genome Res. 14(9), 1733-1740 (2004).
-
(2004)
Genome Res.
, vol.14
, Issue.9
, pp. 1733-1740
-
-
Hattori, N.1
Abe, T.2
Suzuki, M.3
-
11
-
-
77950187447
-
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
-
Feng J, Zhou Y, Campbell SL, et al.: Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat. Neurosci. 13(4), 423-430 (2010).
-
(2010)
Nat. Neurosci.
, vol.13
, Issue.4
, pp. 423-430
-
-
Feng, J.1
Zhou, Y.2
Campbell, S.L.3
-
12
-
-
64249157351
-
Epigenetic reprogramming and induced pluripotency
-
Hochedlinger K, Plath K: Epigenetic reprogramming and induced pluripotency. Development 136(4), 509-523 (2009).
-
(2009)
Development
, vol.136
, Issue.4
, pp. 509-523
-
-
Hochedlinger, K.1
Plath, K.2
-
13
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126(4), 663-676 (2006).
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
14
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, et al.: Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131(5), 861-872 (2007).
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
15
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, et al.: Induced pluripotent stem cell lines derived from human somatic cells. Science (New York) 318(5858), 1917-1920 (2007).
-
(2007)
Science (New York)
, vol.318
, Issue.5858
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
-
16
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB: The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3(6), 415-428 (2002).
-
(2002)
Nat. Rev. Genet.
, vol.3
, Issue.6
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
17
-
-
0023216891
-
Cpg islands in vertebrate genomes
-
Gardiner-Garden M, Frommer M: Cpg islands in vertebrate genomes. J. Mol. Biol. 196(2), 261-282 (1987).
-
(1987)
J. Mol. Biol.
, vol.196
, Issue.2
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
18
-
-
0037133565
-
Comprehensive analysis of CpG islands in human chromosomes 21 and 22
-
Takai D, Jones PA: Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc. Natl Acad. Sci. USA 99(6), 3740-3745 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, Issue.6
, pp. 3740-3745
-
-
Takai, D.1
Jones, P.A.2
-
19
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A, Mikkelsen TS, Gu H, et al.: Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454(7205), 766-770 (2008).
-
(2008)
Nature
, vol.454
, Issue.7205
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
-
20
-
-
51649129596
-
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
-
Mohn F, Weber M, Rebhan M, et al.: Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol. Cell 30(6), 755-766 (2008).
-
(2008)
Mol. Cell
, vol.30
, Issue.6
, pp. 755-766
-
-
Mohn, F.1
Weber, M.2
Rebhan, M.3
-
21
-
-
38649126918
-
Promoter Cpg methylation contributes to ES cell gene regulation in parallel with Oct4/ Nanog, PcG complex, and histone H3 K4/ K27 trimethylation
-
Fouse SD, Shen Y, Pellegrini M, et al.: Promoter Cpg methylation contributes to ES cell gene regulation in parallel with Oct4/ Nanog, PcG complex, and histone H3 K4/ K27 trimethylation. Cell Stem Cell 2(2), 160-169 (2008).
-
(2008)
Cell Stem Cell
, vol.2
, Issue.2
, pp. 160-169
-
-
Fouse, S.D.1
Shen, Y.2
Pellegrini, M.3
-
22
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M, Hellmann I, Stadler MB, et al.: Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat. Genet. 39(4), 457-466 (2007).
-
(2007)
Nat. Genet.
, vol.39
, Issue.4
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
-
23
-
-
64349091471
-
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
-
Ball MP, Li JB, Gao Y, et al.: Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat. Biotechnol. 27(4), 361-368 (2009).
-
(2009)
Nat. Biotechnol.
, vol.27
, Issue.4
, pp. 361-368
-
-
Ball, M.P.1
Li, J.B.2
Gao, Y.3
-
24
-
-
31944432339
-
A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters
-
Saxonov S, Berg P, Brutlag DL: A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters. Proc. Natl Acad. Sci. USA 103(5), 1412-1417 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.5
, pp. 1412-1417
-
-
Saxonov, S.1
Berg, P.2
Brutlag, D.L.3
-
25
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen TS, Ku M, Jaffe DB, et al.: Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448(7153), 553-560 (2007).
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
-
26
-
-
43749098985
-
DNA methylation landscapes: Provocative insights from epigenomics
-
Suzuki MM, Bird A: DNA methylation landscapes: Provocative insights from epigenomics. Nat. Rev. 9(6), 465-476 (2008).
-
(2008)
Nat. Rev.
, vol.9
, Issue.6
, pp. 465-476
-
-
Suzuki, M.M.1
Bird, A.2
-
27
-
-
33847304609
-
Gene body-specific methylation on the active X chromosome
-
Hellman A, Chess A: Gene body-specific methylation on the active X chromosome. Science 315(5815), 1141-1143 (2007).
-
(2007)
Science
, vol.315
, Issue.5815
, pp. 1141-1143
-
-
Hellman, A.1
Chess, A.2
-
28
-
-
64349106730
-
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming
-
Deng J, Shoemaker R, Xie B, et al.: Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat. Biotechnol. 27(4), 353-360 (2009).
-
(2009)
Nat. Biotechnol.
, vol.27
, Issue.4
, pp. 353-360
-
-
Deng, J.1
Shoemaker, R.2
Xie, B.3
-
29
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R, Pelizzola M, Dowen RH, et al.: Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 462(7271), 315-322 (2009).
-
(2009)
Nature
, vol.462
, Issue.7271
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
-
30
-
-
77649267695
-
Dynamic changes in the human methylome during differentiation
-
Laurent L, Wong E, Li G, et al.: Dynamic changes in the human methylome during differentiation. Genome Res. 20(3), 320-331 (2010).
-
(2010)
Genome Res.
, vol.20
, Issue.3
, pp. 320-331
-
-
Laurent, L.1
Wong, E.2
Li, G.3
-
31
-
-
66149147557
-
Developmental programming of CpG island methylation profiles in the human genome
-
Straussman R, Nejman D, Roberts D, et al.: Developmental programming of CpG island methylation profiles in the human genome. Nat. Struct. Mol. Biol. 16(5), 564-571 (2009).
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, Issue.5
, pp. 564-571
-
-
Straussman, R.1
Nejman, D.2
Roberts, D.3
-
32
-
-
72849110608
-
Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells
-
Xu J, Watts JA, Pope SD, et al.: Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes Dev. 23(24), 2824-2838 (2009).
-
(2009)
Genes Dev.
, vol.23
, Issue.24
, pp. 2824-2838
-
-
Xu, J.1
Watts, J.A.2
Pope, S.D.3
-
33
-
-
34547725157
-
Dnmt3l connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
-
Ooi SK, Qiu C, Bernstein E, et al.: Dnmt3l connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 448(7154), 714-717 (2007).
-
(2007)
Nature
, vol.448
, Issue.7154
, pp. 714-717
-
-
Ooi, S.K.1
Qiu, C.2
Bernstein, E.3
-
34
-
-
0034176639
-
Active demethylation of the paternal genome in the mouse zygote
-
Oswald J, Engemann S, Lane N, et al.: Active demethylation of the paternal genome in the mouse zygote. Curr. Biol. 10(8), 475-478 (2000).
-
(2000)
Curr. Biol.
, vol.10
, Issue.8
, pp. 475-478
-
-
Oswald, J.1
Engemann, S.2
Lane, N.3
-
35
-
-
0034598784
-
Demethylation of the zygotic paternal genome
-
Mayer W, Niveleau A, Walter J, Fundele R, Haaf T: Demethylation of the zygotic paternal genome. Nature 403(6769), 501-502 (2000).
-
(2000)
Nature
, vol.403
, Issue.6769
, pp. 501-502
-
-
Mayer, W.1
Niveleau, A.2
Walter, J.3
Fundele, R.4
Haaf, T.5
-
36
-
-
0032528255
-
Chromosome methylation patterns during mammalian preimplantation development
-
Rougier N, Bourchis D, Gomes DM, et al.: Chromosome methylation patterns during mammalian preimplantation development. Genes Dev. 12(14), 2108-2113 (1998).
-
(1998)
Genes Dev.
, vol.12
, Issue.14
, pp. 2108-2113
-
-
Rougier, N.1
Bourchis, D.2
Gomes, D.M.3
-
37
-
-
0036145567
-
Dynamic reprogramming of DNA methylation in the early mouse embryo
-
Santos F, Hendrich B, Reik W, Dean W: Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev. Biol. 241(1), 172-182 (2002).
-
(2002)
Dev. Biol.
, vol.241
, Issue.1
, pp. 172-182
-
-
Santos, F.1
Hendrich, B.2
Reik, W.3
Dean, W.4
-
38
-
-
75749142980
-
A role for the elongator complex in zygotic paternal genome demethylation
-
Okada Y, Yamagata K, Hong K, Wakayama T, Zhang Y: A role for the elongator complex in zygotic paternal genome demethylation. Nature 463(7280), 554-558 (2010).
-
(2010)
Nature
, vol.463
, Issue.7280
, pp. 554-558
-
-
Okada, Y.1
Yamagata, K.2
Hong, K.3
Wakayama, T.4
Zhang, Y.5
-
39
-
-
0027096740
-
Properties and localization of DNA methyltransferase in preimplantation mouse embryos: Implications for genomic imprinting
-
Carlson LL, Page AW, Bestor TH: Properties and localization of DNA methyltransferase in preimplantation mouse embryos: implications for genomic imprinting. Genes Dev. 6(12B), 2536-2541 (1992).
-
(1992)
Genes Dev.
, vol.6
, Issue.12
, pp. 2536-2541
-
-
Carlson, L.L.1
Page, A.W.2
Bestor, T.H.3
-
40
-
-
0033523760
-
DNA methyltransferase is actively retained in the cytoplasm during early development
-
Cardoso MC, Leonhardt H: DNA methyltransferase is actively retained in the cytoplasm during early development. J. Cell Biol. 147(1), 25-32 (1999).
-
(1999)
J. Cell Biol.
, vol.147
, Issue.1
, pp. 25-32
-
-
Cardoso, M.C.1
Leonhardt, H.2
-
41
-
-
0033804210
-
Spatial separation of parental genomes during mouse interspecific (Mus musculus x M. spretus) spermiogenesis
-
Mayer W, Fundele R, Haaf T: Spatial separation of parental genomes during mouse interspecific (Mus musculus x M. spretus) spermiogenesis. Chromosome Res. 8(6), 555-558 (2000).
-
(2000)
Chromosome Res.
, vol.8
, Issue.6
, pp. 555-558
-
-
Mayer, W.1
Fundele, R.2
Haaf, T.3
-
42
-
-
53249133091
-
The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages
-
Kwon GS, Viotti M, Hadjantonakis AK: The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages. Dev. Cell 15(4), 509-520 (2008).
-
(2008)
Dev. Cell
, vol.15
, Issue.4
, pp. 509-520
-
-
Kwon, G.S.1
Viotti, M.2
Hadjantonakis, A.K.3
-
43
-
-
55549119925
-
Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5
-
Ng RK, Dean W, Dawson C, et al.: Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5. Nat. Cell. Biol. 10(11), 1280-1290 (2008).
-
(2008)
Nat. Cell. Biol.
, vol.10
, Issue.11
, pp. 1280-1290
-
-
Ng, R.K.1
Dean, W.2
Dawson, C.3
-
44
-
-
21044438948
-
Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning
-
Donnison M, Beaton A, Davey HW, Broadhurst R, Lhuillier P, Pfeffer PL: Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning. Development 132(10), 2299-2308 (2005).
-
(2005)
Development
, vol.132
, Issue.10
, pp. 2299-2308
-
-
Donnison, M.1
Beaton, A.2
Davey, H.W.3
Broadhurst, R.4
Lhuillier, P.5
Pfeffer, P.L.6
-
45
-
-
58149088296
-
Dynamic transition of Dnmt3b expression in mouse pre- and early post-implantation embryos
-
Hirasawa R, Sasaki H: Dynamic transition of Dnmt3b expression in mouse pre- and early post-implantation embryos. Gene Expr. Patterns 9(1), 27-30 (2009).
-
(2009)
Gene Expr. Patterns
, vol.9
, Issue.1
, pp. 27-30
-
-
Hirasawa, R.1
Sasaki, H.2
-
46
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al.: Embryonic stem cell lines derived from human blastocysts. Science 282(5391), 1145-1147 (1998).
-
(1998)
Science
, vol.282
, Issue.5391
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
-
47
-
-
0029935327
-
Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes
-
Tucker KL, Beard C, Dausmann J, et al.: Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes. Genes Dev. 10(8), 1008-1020 (1996).
-
(1996)
Genes Dev.
, vol.10
, Issue.8
, pp. 1008-1020
-
-
Tucker, K.L.1
Beard, C.2
Dausmann, J.3
-
48
-
-
33745270104
-
Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b
-
Tsumura A, Hayakawa T, Kumaki Y, et al.: Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells 11(7), 805-814 (2006).
-
(2006)
Genes Cells
, vol.11
, Issue.7
, pp. 805-814
-
-
Tsumura, A.1
Hayakawa, T.2
Kumaki, Y.3
-
49
-
-
4744372577
-
Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells
-
Jackson M, Krassowska A, Gilbert N, et al.: Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol. Cell. Biol. 24(20), 8862-8871 (2004).
-
(2004)
Mol. Cell. Biol.
, vol.24
, Issue.20
, pp. 8862-8871
-
-
Jackson, M.1
Krassowska, A.2
Gilbert, N.3
-
50
-
-
20344396373
-
Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein
-
Carlone DL, Lee JH, Young SR, et al.: Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein. Mol. Cell. Biol. 25(12), 4881-4891 (2005).
-
(2005)
Mol. Cell. Biol.
, vol.25
, Issue.12
, pp. 4881-4891
-
-
Carlone, D.L.1
Lee, J.H.2
Young, S.R.3
-
51
-
-
45349086923
-
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes
-
Farthing CR, Ficz G, Ng RK, et al.: Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet. 4(6), e1000116 (2008).
-
(2008)
PLoS Genet.
, vol.4
, Issue.6
-
-
Farthing, C.R.1
Ficz, G.2
Ng, R.K.3
-
52
-
-
0028104109
-
Sp1 elements protect a CpG island from de novo methylation
-
Brandeis M, Frank D, Keshet I, et al.: Sp1 elements protect a CpG island from de novo methylation. Nature 371(6496), 435-438 (1994).
-
(1994)
Nature
, vol.371
, Issue.6496
, pp. 435-438
-
-
Brandeis, M.1
Frank, D.2
Keshet, I.3
-
53
-
-
0037072943
-
A unique developmental pattern of Oct-3/4 DNA methylation is controlled by a cis-demodification element
-
Gidekel S, Bergman Y: A unique developmental pattern of Oct-3/4 DNA methylation is controlled by a cis-demodification element. J. Biol. Chem. 277(37), 34521-34530 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.37
, pp. 34521-34530
-
-
Gidekel, S.1
Bergman, Y.2
-
54
-
-
0034625064
-
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
-
Ramsahoye BH, Biniszkiewicz D, Lyko F, Clark V, Bird AP, Jaenisch R: Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc. Natl Acad. Sci. USA 97(10), 5237-5242 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, Issue.10
, pp. 5237-5242
-
-
Ramsahoye, B.H.1
Biniszkiewicz, D.2
Lyko, F.3
Clark, V.4
Bird, A.P.5
Jaenisch, R.6
-
55
-
-
0035933337
-
Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: The enzyme modifies DNA in a non-processive manner and also methylates non-CpA sites
-
DOI 10.1006/jmbi.2001.4710
-
Gowher H, Jeltsch A: Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites. J. Mol. Biol. 309(5), 1201-1208 (2001). (Pubitemid 32623318)
-
(2001)
Journal of Molecular Biology
, vol.309
, Issue.5
, pp. 1201-1208
-
-
Gowher, H.1
Jeltsch, A.2
-
56
-
-
0036572179
-
De novo methylation of MMLV provirus in embryonic stem cells: CpG versus non-CpG methylation
-
Dodge JE, Ramsahoye BH, Wo ZG, Okano M, Li E: De novo methylation of MMLV provirus in embryonic stem cells: CpG versus non-CpG methylation. Gene 289(1-2), 41-48 (2002).
-
(2002)
Gene
, vol.289
, Issue.1-2
, pp. 41-48
-
-
Dodge, J.E.1
Ramsahoye, B.H.2
Wo, Z.G.3
Okano, M.4
Li, E.5
-
57
-
-
0037087421
-
Differential patterns of methylation of the IFN-g promoter at CpG and non-CpG sites underlie differences in IFN-g gene expression between human neonatal and adult CD45ro- T cells
-
White GP, Watt PM, Holt BJ, Holt PG: Differential patterns of methylation of the IFN-g promoter at CpG and non-CpG sites underlie differences in IFN-g gene expression between human neonatal and adult CD45ro- T cells. J. Immunol. 168(6), 2820-2827 (2002).
-
(2002)
J. Immunol.
, vol.168
, Issue.6
, pp. 2820-2827
-
-
White, G.P.1
Watt, P.M.2
Holt, B.J.3
Holt, P.G.4
-
58
-
-
0042311434
-
Distinct enzymatic properties of recombinant mouse DNA methyltransferases Dnmt3a and Dnmt3b
-
Suetake I, Miyazaki J, Murakami C, Takeshima H, Tajima S: Distinct enzymatic properties of recombinant mouse DNA methyltransferases Dnmt3a and Dnmt3b. J. Biochem. 133(6), 737-744 (2003).
-
(2003)
J. Biochem.
, vol.133
, Issue.6
, pp. 737-744
-
-
Suetake, I.1
Miyazaki, J.2
Murakami, C.3
Takeshima, H.4
Tajima, S.5
-
59
-
-
69149087790
-
Non-CpG methylation of the pgc-1a promoter through Dnmt3b controls mitochondrial density
-
Barres R, Osler ME, Yan J, et al.: Non-CpG methylation of the pgc-1a promoter through Dnmt3b controls mitochondrial density. Cell Metab. 10(3), 189-198 (2009).
-
(2009)
Cell Metab.
, vol.10
, Issue.3
, pp. 189-198
-
-
Barres, R.1
Osler, M.E.2
Yan, J.3
-
60
-
-
0036120654
-
Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality
-
Biniszkiewicz D, Gribnau J, Ramsahoye B, et al.: Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality. Mol. Cell. Biol. 22(7), 2124-2135 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, Issue.7
, pp. 2124-2135
-
-
Biniszkiewicz, D.1
Gribnau, J.2
Ramsahoye, B.3
-
61
-
-
70350654370
-
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
-
Broske AM, Vockentanz L, Kharazi S, et al.: DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat. Genet. 41(11), 1207-1215 (2009).
-
(2009)
Nat. Genet.
, vol.41
, Issue.11
, pp. 1207-1215
-
-
Broske, A.M.1
Vockentanz, L.2
Kharazi, S.3
-
62
-
-
70349469788
-
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
-
Trowbridge JJ, Snow JW, Kim J, Orkin SH: DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell 5(4), 442-449 (2009).
-
(2009)
Cell Stem Cell
, vol.5
, Issue.4
, pp. 442-449
-
-
Trowbridge, J.J.1
Snow, J.W.2
Kim, J.3
Orkin, S.H.4
-
63
-
-
0035656305
-
DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain
-
Takizawa T, Nakashima K, Namihira M, et al.: DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Dev. Cell 1(6), 749-758 (2001).
-
(2001)
Dev. Cell
, vol.1
, Issue.6
, pp. 749-758
-
-
Takizawa, T.1
Nakashima, K.2
Namihira, M.3
-
64
-
-
24344472335
-
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling
-
Fan G, Martinowich K, Chin MH, et al.: DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development 132(15), 3345-3356 (2005).
-
(2005)
Development
, vol.132
, Issue.15
, pp. 3345-3356
-
-
Fan, G.1
Martinowich, K.2
Chin, M.H.3
-
65
-
-
75749104729
-
Dnmt1 maintains progenitor function in self-renewing somatic tissue
-
Sen GL, Reuter JA, Webster DE, Zhu L, Khavari PA: Dnmt1 maintains progenitor function in self-renewing somatic tissue. Nature 463(7280), 563-567 (2010).
-
(2010)
Nature
, vol.463
, Issue.7280
, pp. 563-567
-
-
Sen, G.L.1
Reuter, J.A.2
Webster, D.E.3
Zhu, L.4
Khavari, P.A.5
-
66
-
-
0033515827
-
Multilineage potential of adult human mesenchymal stem cells
-
Pittenger MF, Mackay AM, Beck SC, et al.: Multilineage potential of adult human mesenchymal stem cells. Science 284(5411), 143-147 (1999).
-
(1999)
Science
, vol.284
, Issue.5411
, pp. 143-147
-
-
Pittenger, M.F.1
MacKay, A.M.2
Beck, S.C.3
-
67
-
-
0035067539
-
Multilineage cells from human adipose tissue: Implications for cell-based therapies
-
Zuk PA, Zhu M, Mizuno H, et al.: Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng. 7(2), 211-228 (2001).
-
(2001)
Tissue Eng.
, vol.7
, Issue.2
, pp. 211-228
-
-
Zuk, P.A.1
Zhu, M.2
Mizuno, H.3
-
68
-
-
14844304694
-
Isolation and transcription profiling of purified uncultured human stromal stem cells: Alteration of gene expression after in vitro cell culture
-
Boquest AC, Shahdadfar A, Fronsdal K, et al.: Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture. Mol. Biol. Cell 16(3), 1131-1141 (2005).
-
(2005)
Mol. Biol. Cell
, vol.16
, Issue.3
, pp. 1131-1141
-
-
Boquest, A.C.1
Shahdadfar, A.2
Fronsdal, K.3
-
69
-
-
33746640414
-
Stable CpG hypomethylation of adipogenic promoters in freshly isolated, cultured, and differentiated mesenchymal stem cells from adipose tissue
-
Noer A, Sorensen AL, Boquest AC, Collas P: Stable CpG hypomethylation of adipogenic promoters in freshly isolated, cultured, and differentiated mesenchymal stem cells from adipose tissue. Mol. Biol. Cell 17(8), 3543-3556 (2006).
-
(2006)
Mol. Biol. Cell
, vol.17
, Issue.8
, pp. 3543-3556
-
-
Noer, A.1
Sorensen, A.L.2
Boquest, A.C.3
Collas, P.4
-
70
-
-
77953522433
-
Lineage-specific promoter DNA methylation patterns segregate adult progenitor cell types
-
Epub ahead of print
-
Sorensen AL, Timoskainen S, West FD, et al.: Lineage-specific promoter DNA methylation patterns segregate adult progenitor cell types. Stem Cells Dev. (2009) (Epub ahead of print).
-
(2009)
Stem Cells Dev.
-
-
Sorensen, A.L.1
Timoskainen, S.2
West, F.D.3
-
71
-
-
33846933757
-
Qualification of embryonal carcinoma 2102ep as a reference for human embryonic stem cell research
-
Josephson R, Ording CJ, Liu Y, et al.: Qualification of embryonal carcinoma 2102ep as a reference for human embryonic stem cell research. Stem Cells 25(2), 437-446 (2007).
-
(2007)
Stem Cells
, vol.25
, Issue.2
, pp. 437-446
-
-
Josephson, R.1
Ording, C.J.2
Liu, Y.3
-
72
-
-
70649099225
-
Epigenetic signatures associated with different levels of differentiation potential in human stem cells
-
Aranda P, Agirre X, Ballestar E, et al.: Epigenetic signatures associated with different levels of differentiation potential in human stem cells. PloS ONE 4(11), e7809 (2009).
-
(2009)
PloS ONE
, vol.4
, Issue.11
-
-
Aranda, P.1
Agirre, X.2
Ballestar, E.3
-
73
-
-
34547635995
-
Epigenetic characterization of hematopoietic stem cell differentiation using minichip and bisulfite sequencing analysis
-
Attema JL, Papathanasiou P, Forsberg EC, Xu J, Smale ST, Weissman IL: Epigenetic characterization of hematopoietic stem cell differentiation using minichip and bisulfite sequencing analysis. Proc. Natl Acad. Sci. USA 104(30), 12371-12376 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, Issue.30
, pp. 12371-12376
-
-
Attema, J.L.1
Papathanasiou, P.2
Forsberg, E.C.3
Xu, J.4
Smale, S.T.5
Weissman, I.L.6
-
74
-
-
34547635650
-
Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells
-
Xu J, Pope SD, Jazirehi AR, et al.: Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells. Proc. Natl Acad. Sci. USA 104(30), 12377-12382 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, Issue.30
, pp. 12377-12382
-
-
Xu, J.1
Pope, S.D.2
Jazirehi, A.R.3
-
75
-
-
34247337999
-
De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells
-
Tadokoro Y, Ema H, Okano M, Li E, Nakauchi H: De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells. J. Exp. Med. 204(4), 715-722 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, Issue.4
, pp. 715-722
-
-
Tadokoro, Y.1
Ema, H.2
Okano, M.3
Li, E.4
Nakauchi, H.5
-
76
-
-
0035408256
-
Stem cell plasticity - Building the brain of our dreams
-
Temple S: Stem cell plasticity - building the brain of our dreams. Nat. Rev. Neurosci. 2(7), 513-520 (2001).
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, Issue.7
, pp. 513-520
-
-
Temple, S.1
-
77
-
-
33747879037
-
Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells
-
Shen Y, Chow J, Wang Z, Fan G: Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells. Human Mol. Genet. 15(17), 2623-2635 (2006).
-
(2006)
Human Mol. Genet.
, vol.15
, Issue.17
, pp. 2623-2635
-
-
Shen, Y.1
Chow, J.2
Wang, Z.3
Fan, G.4
-
78
-
-
68049097008
-
Epigenetic dynamics of stem cells and cell lineage commitment: Digging Waddingtons canal
-
Hemberger M, Dean W, Reik W: Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddingtons canal. Nat. Rev. 10(8), 526-537 (2009).
-
(2009)
Nat. Rev.
, vol.10
, Issue.8
, pp. 526-537
-
-
Hemberger, M.1
Dean, W.2
Reik, W.3
-
79
-
-
42249094716
-
Chromatin dynamics during epigenetic reprogramming in the mouse germ line
-
Hajkova P, Ancelin K, Waldmann T, et al.: Chromatin dynamics during epigenetic reprogramming in the mouse germ line. Nature 452(7189), 877-881 (2008).
-
(2008)
Nature
, vol.452
, Issue.7189
, pp. 877-881
-
-
Hajkova, P.1
Ancelin, K.2
Waldmann, T.3
-
80
-
-
77249148019
-
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
-
Popp C, Dean W, Feng S, et al.: Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 463(7284), 1101-1105 (2010).
-
(2010)
Nature
, vol.463
, Issue.7284
, pp. 1101-1105
-
-
Popp, C.1
Dean, W.2
Feng, S.3
-
81
-
-
68549115638
-
Germ line, stem cells, and epigenetic reprogramming
-
Surani MA, Durcova-Hills G, Hajkova P, Hayashi K, Tee WW: Germ line, stem cells, and epigenetic reprogramming. Cold Spring Harb. Symp. Quant. Biol. 73, 9-15 (2008).
-
(2008)
Cold Spring Harb. Symp. Quant. Biol.
, vol.73
, pp. 9-15
-
-
Surani, M.A.1
Durcova-Hills, G.2
Hajkova, P.3
Hayashi, K.4
Tee, W.W.5
-
82
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22
-
Eckhardt F, Lewin J, Cortese R, et al.: DNA methylation profiling of human chromosomes 6, 20 and 22. Nat. Genet. 38(12), 1378-1385 (2006).
-
(2006)
Nat. Genet.
, vol.38
, Issue.12
, pp. 1378-1385
-
-
Eckhardt, F.1
Lewin, J.2
Cortese, R.3
-
83
-
-
34547476585
-
Global, comparative analysis of tissue-specific promoter CpG methylation
-
Schilling E, Rehli M: Global, comparative analysis of tissue-specific promoter CpG methylation. Genomics 90(3), 314-323 (2007).
-
(2007)
Genomics
, vol.90
, Issue.3
, pp. 314-323
-
-
Schilling, E.1
Rehli, M.2
-
84
-
-
38949212693
-
A novel CpG island set identifies tissue-specific methylation at developmental gene loci
-
Illingworth R, Kerr A, Desousa D, et al.: A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol. 6(1), e22 (2008).
-
(2008)
PLoS Biol.
, vol.6
, Issue.1
-
-
Illingworth, R.1
Kerr, A.2
Desousa, D.3
-
85
-
-
50649108994
-
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)
-
Rakyan VK, Down TA, Thorne NP, et al.: An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs). Genome Res. 18(9), 1518-1529 (2008).
-
(2008)
Genome Res.
, vol.18
, Issue.9
, pp. 1518-1529
-
-
Rakyan, V.K.1
Down, T.A.2
Thorne, N.P.3
-
86
-
-
58149490976
-
Tissue specific differentially methylated regions (TDMR): Changes in DNA methylation during development
-
Song F, Mahmood S, Ghosh S, et al.: Tissue specific differentially methylated regions (TDMR): changes in DNA methylation during development. Genomics 93(2), 130-139 (2009).
-
(2009)
Genomics
, vol.93
, Issue.2
, pp. 130-139
-
-
Song, F.1
Mahmood, S.2
Ghosh, S.3
-
87
-
-
70649095120
-
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
-
Doi A, Park IH, Wen B, et al.: Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat. Genet. 41(12), 1350-1353 (2009).
-
(2009)
Nat. Genet.
, vol.41
, Issue.12
, pp. 1350-1353
-
-
Doi, A.1
Park, I.H.2
Wen, B.3
-
88
-
-
34249909232
-
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
-
Maherali N, Sridharan R, Xie W, et al.: Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1(1), 55-70 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, Issue.1
, pp. 55-70
-
-
Maherali, N.1
Sridharan, R.2
Xie, W.3
-
89
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
Mikkelsen TS, Hanna J, Zhang X, et al.: Dissecting direct reprogramming through integrative genomic analysis. Nature 454(7200), 49-55 (2008).
-
(2008)
Nature
, vol.454
, Issue.7200
, pp. 49-55
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, X.3
-
90
-
-
70350536767
-
A small-molecule inhibitor of TGF-b signaling replaces sox2 in reprogramming by inducing nanog
-
Ichida JK, Blanchard J, Lam K, et al.: A small-molecule inhibitor of TGF-b signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell 5(5), 491-503 (2009).
-
(2009)
Cell Stem Cell
, vol.5
, Issue.5
, pp. 491-503
-
-
Ichida, J.K.1
Blanchard, J.2
Lam, K.3
-
91
-
-
73349104113
-
Active DNA demethylation mediated by DNA glycosylases
-
Zhu JK: Active DNA demethylation mediated by DNA glycosylases. Annu. Rev. Genet. 43, 143-166 (2009).
-
(2009)
Annu. Rev. Genet.
, vol.43
, pp. 143-166
-
-
Zhu, J.K.1
-
92
-
-
60749094831
-
Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis
-
Ma DK, Jang MH, Guo JU, et al.: Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 323(5917), 1074-1077 (2009).
-
(2009)
Science
, vol.323
, Issue.5917
, pp. 1074-1077
-
-
Ma, D.K.1
Jang, M.H.2
Guo, J.U.3
-
93
-
-
33846933274
-
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
-
Barreto G, Schafer A, Marhold J, et al.: Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 445(7128), 671-675 (2007).
-
(2007)
Nature
, vol.445
, Issue.7128
, pp. 671-675
-
-
Barreto, G.1
Schafer, A.2
Marhold, J.3
-
94
-
-
10644282845
-
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming
-
Morgan HD, Dean W, Coker HA, Reik W, Petersen-Mahrt SK: Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J. Biol. Chem. 279(50), 52353-52360 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.50
, pp. 52353-52360
-
-
Morgan, H.D.1
Dean, W.2
Coker, H.A.3
Reik, W.4
Petersen-Mahrt, S.K.5
-
95
-
-
41949136533
-
GADD45A does not promote DNA demethylation
-
Jin SG, Guo C, Pfeifer GP: GADD45A does not promote DNA demethylation. PLoS Genet. 4(3), e1000013 (2008).
-
(2008)
PLoS Genet.
, vol.4
, Issue.3
-
-
Jin, S.G.1
Guo, C.2
Pfeifer, G.P.3
-
96
-
-
40449123137
-
Cyclical DNA methylation of a transcriptionally active promoter
-
Metivier R, Gallais R, Tiffoche C, et al.: Cyclical DNA methylation of a transcriptionally active promoter. Nature 452(7183), 45-50 (2008).
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 45-50
-
-
Metivier, R.1
Gallais, R.2
Tiffoche, C.3
-
97
-
-
77649104794
-
Reprogramming towards pluripotency requires AID-dependent DNA demethylation
-
Bhutani N, Brady JJ, Damian M, Sacco A, Corbel SY, Blau HM: Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature 463(7284), 1042-1047 (2009).
-
(2009)
Nature
, vol.463
, Issue.7284
, pp. 1042-1047
-
-
Bhutani, N.1
Brady, J.J.2
Damian, M.3
Sacco, A.4
Corbel, S.Y.5
Blau, H.M.6
-
98
-
-
67649222358
-
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures
-
Chin MH, Mason MJ, Xie W, et al.: Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell 5(1), 111-123 (2009).
-
(2009)
Cell Stem Cell
, vol.5
, Issue.1
, pp. 111-123
-
-
Chin, M.H.1
Mason, M.J.2
Xie, W.3
-
99
-
-
33748274499
-
Human embryonic stem cells have a unique epigenetic signature
-
Bibikova M, Chudin E, Wu B, et al.: Human embryonic stem cells have a unique epigenetic signature. Genome Res. 16(9), 1075-1083 (2006).
-
(2006)
Genome Res.
, vol.16
, Issue.9
, pp. 1075-1083
-
-
Bibikova, M.1
Chudin, E.2
Wu, B.3
-
100
-
-
34249897719
-
Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome
-
Allegrucci C, Wu YZ, Thurston A, et al.: Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome. Human Mol. Genet. 16(10), 1253-1268 (2007).
-
(2007)
Human Mol. Genet.
, vol.16
, Issue.10
, pp. 1253-1268
-
-
Allegrucci, C.1
Wu, Y.Z.2
Thurston, A.3
-
101
-
-
27144538978
-
Genomic alterations in cultured human embryonic stem cells
-
Maitra A, Arking DE, Shivapurkar N, et al.: Genomic alterations in cultured human embryonic stem cells. Nat. Genet. 37(10), 1099-1103 (2005).
-
(2005)
Nat. Genet.
, vol.37
, Issue.10
, pp. 1099-1103
-
-
Maitra, A.1
Arking, D.E.2
Shivapurkar, N.3
-
103
-
-
55749089875
-
Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
-
Aasen T, Raya A, Barrero MJ, et al.: Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat. Biotechnol. 26(11), 1276-1284 (2008).
-
(2008)
Nat. Biotechnol.
, vol.26
, Issue.11
, pp. 1276-1284
-
-
Aasen, T.1
Raya, A.2
Barrero, M.J.3
-
104
-
-
12344266614
-
5-azacytidine induces cardiac differentiation of p19 embryonic stem cells
-
Choi SC, Yoon J, Shim WJ, Ro YM, Lim DS: 5-azacytidine induces cardiac differentiation of p19 embryonic stem cells. Exp. Mol. Med. 36(6), 515-523 (2004).
-
(2004)
Exp. Mol. Med.
, vol.36
, Issue.6
, pp. 515-523
-
-
Choi, S.C.1
Yoon, J.2
Shim, W.J.3
Ro, Y.M.4
Lim, D.S.5
-
105
-
-
55749104227
-
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
-
Huangfu D, Osafune K, Maehr R, et al.: Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat. Biotechnol. 26(11), 1269-1275 (2008).
-
(2008)
Nat. Biotechnol.
, vol.26
, Issue.11
, pp. 1269-1275
-
-
Huangfu, D.1
Osafune, K.2
Maehr, R.3
-
106
-
-
46949085597
-
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
-
Huangfu D, Maehr R, Guo W, et al.: Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat. Biotechnol. 26(7), 795-797 (2008).
-
(2008)
Nat. Biotechnol.
, vol.26
, Issue.7
, pp. 795-797
-
-
Huangfu, D.1
Maehr, R.2
Guo, W.3
-
107
-
-
54949115497
-
Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds
-
Shi Y, Desponts C, Do JT, Hahm HS, Scholer HR, Ding S: Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell 3(5), 568-574 (2008).
-
(2008)
Cell Stem Cell
, vol.3
, Issue.5
, pp. 568-574
-
-
Shi, Y.1
Desponts, C.2
Do, J.T.3
Hahm, H.S.4
Scholer, H.R.5
Ding, S.6
-
108
-
-
44349103591
-
A combined chemical and genetic approach for the generation of induced pluripotent stem cells
-
Shi Y, Do JT, Desponts C, Hahm HS, Scholer HR, Ding S: A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell 2(6), 525-528 (2008).
-
(2008)
Cell Stem Cell
, vol.2
, Issue.6
, pp. 525-528
-
-
Shi, Y.1
Do, J.T.2
Desponts, C.3
Hahm, H.S.4
Scholer, H.R.5
Ding, S.6
-
109
-
-
0035495740
-
Brain from bone: Efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with noggin or a demethylating agent
-
Kohyama J, Abe H, Shimazaki T, et al.: Brain from bone: efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with noggin or a demethylating agent. Differentiation 68(4-5), 235-244 (2001).
-
(2001)
Differentiation
, vol.68
, Issue.4-5
, pp. 235-244
-
-
Kohyama, J.1
Abe, H.2
Shimazaki, T.3
-
110
-
-
0037106144
-
Adult bone marrow stromal stem cells express germline, ectodermal, endodermal, and mesodermal genes prior to neurogenesis
-
Woodbury D, Reynolds K, Black IB: Adult bone marrow stromal stem cells express germline, ectodermal, endodermal, and mesodermal genes prior to neurogenesis. J. Neurosci. Res. 69(6), 908-917 (2002).
-
(2002)
J. Neurosci. Res.
, vol.69
, Issue.6
, pp. 908-917
-
-
Woodbury, D.1
Reynolds, K.2
Black, I.B.3
-
111
-
-
38649108184
-
Unraveling epigenetic regulation in embryonic stem cells
-
Bibikova M, Laurent LC, Ren B, Loring JF, Fan JB: Unraveling epigenetic regulation in embryonic stem cells. Cell Stem Cell 2(2), 123-134 (2008).
-
(2008)
Cell Stem Cell
, vol.2
, Issue.2
, pp. 123-134
-
-
Bibikova, M.1
Laurent, L.C.2
Ren, B.3
Loring, J.F.4
Fan, J.B.5
-
112
-
-
67649669255
-
A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling
-
Ramirez-Carrozzi VR, Braas D, Bhatt DM, et al.: A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling. Cell 138(1), 114-128 (2009).
-
(2009)
Cell
, vol.138
, Issue.1
, pp. 114-128
-
-
Ramirez-Carrozzi, V.R.1
Braas, D.2
Bhatt, D.M.3
-
113
-
-
41749108163
-
Stem cell regulation by polycomb repressors: Postponing commitment
-
Pietersen AM, Van Lohuizen M: Stem cell regulation by polycomb repressors: postponing commitment. Curr. Opin. Cell Biol. 20(2), 201-207 (2008).
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, Issue.2
, pp. 201-207
-
-
Pietersen, A.M.1
Van Lohuizen, M.2
-
114
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, et al.: Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324(5929), 930-935 (2009).
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
-
115
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis S, Heintz N: The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324(5929), 929-930 (2009).
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
116
-
-
39349105090
-
Expanding chemical biology of 2-oxoglutarate oxygenases
-
Loenarz C, Schofield CJ: Expanding chemical biology of 2-oxoglutarate oxygenases. Nature Chem. Biol. 4(3), 152-156 (2008).
-
(2008)
Nature Chem. Biol.
, vol.4
, Issue.3
, pp. 152-156
-
-
Loenarz, C.1
Schofield, C.J.2
|