De novo methylation of MMLV provirus in embryonic stem cells: CpG versus non-CpG methylation

Gene

Volumn 289, Issue 1-2, 2002, Pages 41-48

  Dodge, Jonathan E ^a   Ramsahoye, Bernard H ^b   Wo, Z Galen ^a   Okano, Masaki ^a   Li, En ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

5 Methylcytosine; Dnmt1; Dnmt3a; Dnmt3b; Embryonic stem cell

Indexed keywords

BISULFITE; DNA METHYLTRANSFERASE; PROTEIN DNMT1; PROTEIN DNMT3A; PROTEIN DNMT3B; UNCLASSIFIED DRUG; VIRUS DNA;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; DNA METHYLATION; LEUKEMIA VIRUS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN METHYLATION; PROVIRUS; SEQUENCE ANALYSIS; STEM CELL; WILD TYPE;

5-METHYLCYTOSINE; ANIMALS; CPG ISLANDS; CYTOSINE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA, VIRAL; EMBRYO; MICE; MOLONEY MURINE LEUKEMIA VIRUS; MUTATION; PROVIRUSES; SEQUENCE ANALYSIS, DNA; STEM CELLS;

MURINAE;

EID: 0036572179     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(02)00469-9     Document Type: Article

References (23)

1. Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases
2. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
3. High sensitivity mapping of methylated cytosines
4. CpNpG methylation in mammalian cells
5. Selective variegated methylation of the p15 CpG island in acute myeloid leukemia
6. Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: The enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites
7. De novo methylation and expression of retroviral genomes during mouse embryogenesis
8. RNA-directed transcriptional gene silencing in plants can be inherited independently of the RNA trigger and requires Met1 for maintenance
9. De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells
10. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
11. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
12. Requirement of chromomethylase3 for maintenance of cpxpg methylation
13. Dynamic analysis of proviral induction and de novo methylation: Implications for a histone deacetylase-independent, methylation density-dependent mechanism of transcriptional repression
14. Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila
15. CmC(A/T)GG DNA methylation in mature B cell lymphoma gene silencing
16. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
17. Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells
18. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
19. Heavy de novo methylation at symmetrical and non-symmetrical sites is a hallmark of RNA-directed DNA methylation
20. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
21. DNA methylation in health and disease
22. The somatic replication of DNA methylation
23. A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast