Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality

Molecular and Cellular Biology

Volumn 22, Issue 7, 2002, Pages 2124-2135

  Biniszkiewicz, Detlev ^a   Gribnau, Joost ^a   Ramsahoye, Bernard ^a   Gaudet, François ^a   Eggan, Kevin ^a   Humpherys, David ^a   Mastrangelo, Mary Ann ^a   Jun, Zhan ^a   Walter, Jörn ^a   Jaenisch, Rudolf ^a  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE; PROTEIN DNMT1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BLASTOCYST; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; EMBRYOTOXICITY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE OVEREXPRESSION; GENE SILENCING; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RETROVIRUS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STEM CELL; TRANSGENE; WESTERN BLOTTING;

ALLELES; ANIMALS; BLOTTING, WESTERN; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EMBRYO LOSS; GENE DELETION; GENE DOSAGE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE ORDER; GENE SILENCING; GENOME; GENOMIC IMPRINTING; IN SITU HYBRIDIZATION, FLUORESCENCE; MICE; POLYPLOIDY; PROTEIN KINASES; PROTEINS; RECEPTOR, IGF TYPE 2; RNA, MESSENGER; RNA, UNTRANSLATED; STEM CELLS; TRANSCRIPTION FACTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); UNIDENTIFIED RETROVIRUS;

EID: 0036120654     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.7.2124-2135.2002     Document Type: Article

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