The role of epoxidation and electrophile-responsive element-regulated gene transcription in the potentially beneficial and harmful effects of the coffee components cafestol and kahweol

Journal of Nutritional Biochemistry

Volumn 21, Issue 8, 2010, Pages 757-763

  van Cruchten, Saskia T J ^a,b   de Haan, Laura H J ^a   Mulder, Patrick P J ^a   Kunne, Cindy ^c   Boekschoten, Mark V ^a,b   Katan, Martijn B ^d   Aarts, Jac M M J G ^a   Witkamp, Renger F ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Cafestol; Diterpenes; Electrophile responsive element; Epoxidation; Glutathione; Metabolism

Indexed keywords

ACETYLCYSTEINE; BUTHIONINE SULFOXIMINE; CAFESTOL; CYTOCHROME P450; ELECTROPHILE; GLUCURONIDE; GLUTATHIONE; KAHWEOL; LUCIFERASE; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BILE DUCT; BIOTRANSFORMATION; CANNULATION; COFFEE; CONTROLLED STUDY; ELECTROPHILE RESPONSIVE ELEMENT; EPOXIDATION; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSCRIPTION; HEPATOMA CELL; HYPOTHESIS; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLIC ACTIVATION; MODULATION; MOUSE; NONHUMAN; OXIDATION; REGULATOR GENE; REPORTER GENE;

ANIMALS; BILE; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; COFFEE; DITERPENES; EPOXY COMPOUNDS; GENE EXPRESSION REGULATION; HUMANS; MALE; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; TRANSCRIPTION, GENETIC;

MURINAE; MUS;

EID: 77954658473     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2009.05.001     Document Type: Article

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