Cafestol, the cholesterol-raising factor in boiled coffee, suppresses bile acid synthesis by downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase in rat hepatocytes

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 17, Issue 11, 1997, Pages 3064-3070

  Post, Sabine M ^a   De Wit, Elly C M ^a   Princen, Hans M G ^a,b  

^a TNO   (Netherlands)

^b NONE   (Netherlands)

Author keywords

Bile acid synthesis; Cafestol; Cholesterol 7 hydroxylase; Rat hepatocytes; Sterol 27 hydroxylase

Indexed keywords

BILE ACID; CAFESTOL; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLESTEROL ESTER; DITERPENE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; ISOKAHWEOL; KAHWEOL; LITHOCHOLIC ACID; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; OXYGENASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BILE ACID SYNTHESIS; COFFEE; DRUG EFFECT; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HYPERCHOLESTEROLEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031456961     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.17.11.3064     Document Type: Article

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