Effect of a coffee lipid (cafestol) on cholesterol metabolism in human skin fibroblasts

Journal of Lipid Research

Volumn 39, Issue 4, 1998, Pages 901-912

  Halvorsen, Bente ^a   Ranheim, Trine ^a   Nenseter, Marit S ^a   Huggett, Anthony C ^b   Drevon, Christian A ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

25 hydroxycholesterol; Cafestol; Kahweol; LDL receptor; Low density lipoprotein

Indexed keywords

CELLOBIOSE; CHLORAMPHENICOL ACETYLTRANSFERASE; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LIPID; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; OLEIC ACID; TYRAMINE;

ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; COFFEE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; RECEPTOR GENE; SKIN FIBROBLAST; TRANSCRIPTION REGULATION;

ACETATES; CELLS, CULTURED; CHOLESTEROL; CHOLESTEROL ESTERS; COFFEE; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GENE EXPRESSION; HUMANS; HYDROXYCHOLESTEROLS; LIPIDS; LIPOPROTEINS, LDL; OLEIC ACID; PROMOTER REGIONS (GENETICS); RECEPTORS, LDL; RNA, MESSENGER; SKIN; STEROL O-ACYLTRANSFERASE;

EID: 0031977243     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Thelle, D. S., E. Arnesen, and O. H. Førde. 1983. The Tromsø heart study. Does coffee raise serum cholesterol? N. Engl. J. Med. 308: 1454-1457.
2. Bønaa, K., E. Arnesen, D. S. Thelle, and O. H. Førde. 1988. Coffee and cholesterol: is it all in the brewing? The Tromsø Study. Br. Med. J. 297: 1103-1104.
3. Aro, A., J. Teirila, and C. G. Gref. 1990. Dose-dependent effect on serum cholesterol and apoprotein B concentrations by consumption of boiled, non-filtered coffee. Atherosclerosis 83: 257-261.
4. Aro, A., J. Tuomilehto, E. Kostiainen, U. Uusitalo, and P. Pietinen. 1987. Boiled coffee increases serum low density lipoprotein concentration. Metabolism 36: 1027-1030.
5. Bak, A. A., and D. E. Grobbee. 1989. The effect on serum cholesterol levels of coffee brewed by filtering or boiling. N. Engl. J. Med. 321: 1432-1437.
6. Ratnayake, W. M., R. Hollywood, E. O'Grady, and B. Stavric. 1993. Lipid content and composition of coffee brews prepared by different methods. Food Chem. Toxicol. 31: 263-269.
7. van Dusseldorp, M., M. B. Katan, T. van Vliet, P. N. Demacker, and A. F. Stalenhoef. 1991. Cholesterol-raising factor from boiled coffee does not pass a paper filter. Arterioscler. Thromb. 11: 586-593.
8. Urgert, R., and M. B. Katan. 1996. The cholesterol-raising factor from coffee beans. J. R. Soc. Med. 89: 618-623.
9. Zock, P. L., M. B. Katan, M. P. Merkus, M. van Dusseldorp, and J. L. Harryvan. 1990. Effect of a lipid-rich fraction from boiled coffee on serum cholesterol. Lancet. 335: 1235-1237.
10. Weusten-Van der Wouw, M. P., M. B. Katan, R. Viani, A. C. Huggett, R. Liardon, R. Liardon, P. G. Lund-Larsen, D. S. Thelle, I. Ahola, A. Aro, S. Meyboom, and A. C. Beynen. 1994. Identity of the cholesterol-raising factor from boiled coffee and its effects on liver function enzymes. J. Lipid. Res. 35: 721-733.
11. Goldstein, J. L., and M. S. Brown. 1977. The low-density lipoprotein pathway and its relation to atherosclerosis. Annu. Rev. Biochem. 46: 897-930.
12. Goldstein, J. L., and M. S. Brown. 1990. Regulation of the mevalonate pathway. Nature 343: 425-430.
13. Smith, P. K., R. I. Krohn, G. T. Hermanson, A. K. Mallia, F. H. Gartner, M. D. Provenzano, E. K. Fujimoto, N. M. Goeke, B. J. Olson, and D. C. Klenk. 1985. Measurement of protein using bicinchoninic acid. Anal. Biochem. 150: 76-85.
14. Havel, R. J., H. A. Eder, and J. H. Bragdon. 1955. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Clin. Invest. 34: 1345-1353.
15. Pittman, R. C., T. E. Carew, C. K. Glass, S. R. Green, C. Taylor, Jr., and A. D. Attie. 1983. A radioiodiated, intracellularly trapped ligand for determining the sites of plasma protein degradation in vivo. Biochem. J. 212: 791-800.
16. Brown, M. S., and J. L. Goldstein. 1975. Regulation of the activity of the low density lipoprotein receptor in human fibroblasts. Cell. 6: 307-316.
17. Hulme, E. C., and N. J. M. Birdsall. 1992. Strategy and tactics in receptor-binding studies. In Receptor-Ligand Interactions: a Practical Approach. E. C. Hulme, editor. Oxford University Press, New York, NY. 63-174.
18. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
19. Peacock, S. L., M. P. Bates, D. W. Russell, M. S. Brown, and J. L. Goldstein. 1988. Human low density lipoprotein receptor expressed in Xenopus oocytes. Conserved signals for O-linked glycosylation and receptor-mediated endocytosis. J. Biol. Chem. 263: 7838-7845.
20. Arcari, P., R. Martinelli, and F. Salvatore. 1984. The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species. Nucleic Acids Res. 12: 9179-9189.
21. Church, G. M., and W. Gilbert. 1984. Genomic sequencing. Proc. Natl. Acad. Sci. USA. 81: 1991-1995.
22. Yokoyama, C., X. Wang, M. R. Briggs, A. Admon, J. Wu, X. Hua, J. L. Goldstein, and M. S. Brown. 1993. SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell. 75: 187-197.
23. Lee, F., C. V. Hall, G. M. Ringold, D. E. Dobson, J. Luh, and P. E. Jacob. 1984. Functional analysis of the steroid hormone control region of mouse mammary tumor virus. Nucleic Acids Res. 12: 4191-4206.
24. Gorman, C. M., L. F. Moffatt, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2: 1044-1051.
25. Rustan, A. C., J. O. Nossen, H. Osmundsen, and C. A. Drevon. 1988. Eicosapentaenoic acid inhibits cholesterol esterification in cultured parenchymal cells and isolated microsomes from rat liver. J. Biol. Chem. 263: 8126-8132.
26. Folch, J., M. Lees, and G. H. Sloane Stanley. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226: 497-509.
27. Edwards, P. A., A. M. Fogelman, and G. Popjak. 1976. A direct relationship between the amount of sterol lost from rat hepatocytes and the increase in activity of HMG-CoA reductase. Biochem. Biophys. Res. Commun. 68: 64-69.
28. Sharkey, M. F., A. Miyanohara, R. L. Elam, T. Friedmann, and J. L. Witztum. 1990. Post-transcriptional regulation of retroviral vector-transduced low density lipoprotein receptor activity. J. Lipid. Res. 31: 2167-2178.
29. Wang, X., M. R. Briggs, X. Hua, C. Yokoyama, J. L. Goldstein, and M. S. Brown. 1993. Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. II. Purification and characterization. J. Biol. Chem. 268: 14497-14504.
30. Wang, X., R. Sato, M. S. Brown, X. Hua, and J. L. Goldstein. 1994. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell 77: 53-62.
31. Gasic, G. P. 1994. Basic-helix-loop-helix transcription factor and sterol sensor in a single membrane-bound molecule. Cell. 77: 17-19.
32. Ranheim, T., B. Halvorsen, A. C. Huggett, R. Blomhoff, and C. A. Drevon. 1995. Effect of a coffee lipid (cafestol) on regulation of lipid metabolism in CaCo-2 cells. J. Lipid. Res. 36: 2079-2089.
33. Edwards, E. H., E. A. Sprague, J. L. Kelley, J. J. Kerbacher, C. J. Schwartz, and A. D. Elbein. 1989. Castanospermine inhibits the function of the low-density lipoprotein receptor. Biochemistry. 28: 7679-7687.
34. Lodish, H. F., and N. Kong. 1984. Glucose removal from N-linked oligosaccharides is required for efficient maturation of certain secretory glycoproteins from the rough endoplasmic reticulum to the Golgi complex. J. Cell Biol. 98: 1720-1729.
35. Fong, L. G. 1994. Posttransitional regulation of macrophage scavenger receptor by protein phosphorylation. Circulation. 90(suppl I): I-189. Abstract.
36. Fong, L. G. 1996. Modulation of macrophage scavenger receptor transport by protein phosphorylation. J. Lipid. Res. 37: 574-587.
37. Tanaka, R. D., A. C. Li, A. M. Fogelman, and P. A. Edwards. 1986. Inhibition of lysosomal protein degradation inhibits the basal degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase. J. Lipid. Res. 27: 261-273.
38. Tanaka, R. D., P. A. Edwards, S. F. Lan, and A. M. Fogelman. 1983. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in avian myeloblasts. Mode of action of 25-hydroxycholesterol. J. Biol. Chem. 258: 13331-13339.
39. Hochstrasser, M. 1996. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30: 405-439.
40. Drevon, C. A., D. B. Weinstein, and D. Steinberg. 1980. Regulation of cholesterol esterification and biosynthesis in monolayer cultures of normal adult rat hepatocytes. J. Biol. Chem. 255: 9128-9137.
41. Drevon, C. A., A. D. Attie, S. H. Pangburn, and D. Steinberg. 1981. Metabolism of homologous and heterologous lipoproteins by cultured rat and human skin fibroblasts. J. Lipid. Res. 22: 37-46.
42. Hashimoto, S., C. A. Drevon, D. B. Weinstein, J. S. Bernett, S. Dayton, and D. Steinberg. 1983. Activity of acyl-CoA: cholesterol acyltransferase and 3-hydroxy-3-methylglutaryl-CoA reductase in subfractions of hepatic microsomes enriched with cholesterol. Biochim. Biophys. Acta. 754: 126-133.
43. Steinberg, D., S. Parthasarathy, T. E. Carew, J. C. Khoo, and J. L. Witztum. 1989. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320: 915-924.
44. Gavey, K. L., D. L. Trujillo, and T. J. Scallen. 1983. Evidence for phosphorylation/dephosphorylation of rat liver acyl-CoA:cholesterol acyltransferase. Proc. Natl. Acad. Sci. USA. 80: 2171-2174.
45. Suckling, K. E., E. F. Stange, and J. M. Dietschy. 1983. In vivo modulation of rat liver acyl-coenzyme A:cholesterol acyltransferase by phosphorylation and substrate supply. FEBS Lett. 159: 29-32.
46. Kwok, C. T., J. L. Smith, S. P. Pillay, and I. R. Hardie. 1984. Inactivation of acyl-CoA:cholesterol acyltransferase by ATP+Mg2+ in rat liver microsomes. Biochem. Int. 8: 271-282.
47. Faust, J. R., K. L. Luskey, D. J. Chin, J. L. Goldstein, and M. S. Brown. 1982. Regulation of synthesis and degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by low density lipoprotein and 25-hydroxycholesterol in UT-1 cells Proc. Natl. Acad. Sci. USA. 79: 5205-5209.
48. Luskey, K. L., and B. Stevens. 1985. Human 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation. J. Biol. Chem. 260: 10271-10277.
49. 865 of Syrian hamster 3-hydroxy-3-methylglutaryl-CoA reductase. J. Biol. Chem. 269: 16862-16866.