The Type 1 Diabetes PhysioLab® Platform: A validated physiologically based mathematical model of pathogenesis in the non-obese diabetic mouse

Clinical and Experimental Immunology

Volumn 161, Issue 2, 2010, Pages 250-267

  Shoda, L ^a   Kreuwel, H ^b   Gadkar, K ^c   Zheng, Y ^d   Whiting, C ^f   Atkinson, M ^h   Bluestone, J ^g   Mathis, D ⁱ   Young, D ^c   Ramanujan, S ^e  

^a Entelos Inc   (United States)

^b BAXTER HEALTHCARE CORPORATION   (United States)

^c Theranos Inc   (United States)

^d GENENTECH INC   (United States)

^e Crescendo Bioscience   (United States)

^f STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF FLORIDA   (United States)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

Author keywords

mathematical model; NOD mouse; pathogenesis; therapies; type 1 diabetes

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN;

ACCURACY; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CELL LOSS; DENDRITIC CELL; DEVICE; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; LYMPH NODE; MACROPHAGE; MATHEMATICAL MODEL; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REPRODUCTION; SIMULATION; VALIDATION PROCESS;

ALGORITHMS; ANIMALS; COMPUTER SIMULATION; DIABETES MELLITUS, TYPE 1; LYMPH NODES; MICE; MICE, INBRED NOD; MODELS, BIOLOGICAL; MODELS, IMMUNOLOGICAL; PANCREAS;

EID: 77954637421     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2010.04166.x     Document Type: Article

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