Cutting edge: Secondary lymphoid organs are essential for maintaining the CD4, but not CD8, naive T cell pool

Journal of Immunology

Volumn 167, Issue 12, 2001, Pages 6711-6715

  Dai, Z ^a   Lakkis, F G ^a  

^a LMP 2073 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; HERMES ANTIGEN; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; LYMPHOCYTOPENIA; LYMPHOID ORGAN; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE SUBPOPULATION; THYMECTOMY; THYMUS;

EID: 0035892904     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.12.6711     Document Type: Article

References (35)

1. Selecting and maintaining a diverse T-cell repertoire
2. The life span of naive α/β T cells in secondary lymphoid organs
3. Turnover of naive- and memory-phenotype T cells
4. The role of the thymus and recent thymic migrants in the maintenance of the adult peripheral lymphocyte pool
5. Differential requirements for survival and proliferation of CD8 naive or memory T cells
6. Homeostatic T cell proliferation: How far can T cells be activated to self-ligands?
7. + T cells, but affect their long-term life span
8. Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules
9. Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells
10. Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses
11. Persistence of memory CD8 T cells in MHC class I-deficient mice
12. Designing and maintaining the mature TCR repertoire: The continuum of self-peptide:self-MHC complex recognition
13. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
14. IL-7 is critical for homeostatic proliferation and survival of naive T cells
15. Lymphocyte life-span and memory
16. Population biology of lymphocytes: The flight for survival
17. + T cells
18. Antigen localisation regulates immune responses in a dose- and time-dependent fashion: A geographical view of immune reactivity
19. Immunologic "ignorance" of vascularized organ transplants in the absence of secondary lymphoid tissue
20. A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice
21. The effect of thymectomy on the lymphoid tissues of the mouse
22. Effect of thymectomy in adult mice on immunological responsiveness
23. Functional heterogeneity among the T-derived lymphocytes of the mouse. I. Analysis by adult thymectomy
24. On the lifespan of virgin T lymphocytes
25. Visualizing the generation of memory CD4 T cells in the whole body
26. Bcl-2 rescues T lymphopolesis in interleukin-7 receptor-deficient mice
27. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
28. - T cells in lymphopenic hosts
29. + T cell survival is not directly linked to self-MHC-induced TCR signaling
30. + T cells in the absence of self peptide:MHC complexes
31. Alymphoplasia is caused by a point mutation in the mouse gene encoding NF-κB-inducing kinase
32. Immunodeficiency of alymphoplasia mice (aly/aly) in vivo: Structural defect of secondary lymphoid organs and functional B cell defect
33. Autologous regulation of naive T cell homeostasis within the T cell compartment
34. Chemokines and cell migration in secondary lymphoid organs
35. Class II-independent generation of CD4 memory T cells from effectors