메뉴 건너뛰기




Volumn 34, Issue 5, 2004, Pages 1395-1404

Increased NF-κB activity in B cells and bone marrow-derived dentritic cells from NOD mice

Author keywords

B cell; Dentritic cell; NF B; NOD mouse; Type 1 diabetes

Indexed keywords

B7 ANTIGEN; BIOLOGICAL MARKER; CD40 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; AUTOANTIGEN; INSULIN; MEMBRANE PROTEIN; PROTEIN TYROSINE PHOSPHATASE; PTPRN2 PROTEIN, HUMAN;

EID: 2942746324     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200324490     Document Type: Article
Times cited : (52)

References (37)
  • 1
    • 0027979956 scopus 로고
    • Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant
    • Serreze, D. V., Leiter, E. H., Christianson, G. J., Greiner, D. and Roopenian, D. C., Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant. Diabetes 1994. 43: 505-509.
    • (1994) Diabetes , vol.43 , pp. 505-509
    • Serreze, D.V.1    Leiter, E.H.2    Christianson, G.J.3    Greiner, D.4    Roopenian, D.C.5
  • 2
    • 0028900297 scopus 로고
    • Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse
    • Lenschow, D. J., Ho, S. C., Sattar, H., Rhee, L., Gray, G., Nabavi, N., Herold, K. C. and Bluestone, J. A., Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. J. Exp. Med. 1995. 181: 1145-1155.
    • (1995) J. Exp. Med. , vol.181 , pp. 1145-1155
    • Lenschow, D.J.1    Ho, S.C.2    Sattar, H.3    Rhee, L.4    Gray, G.5    Nabavi, N.6    Herold, K.C.7    Bluestone, J.A.8
  • 4
    • 0031854250 scopus 로고    scopus 로고
    • Splenic macrophages from the NOD mouse are defective in the ability to present antigen
    • Piganelli, J. D., Martin, T. and Haskins, K., Splenic macrophages from the NOD mouse are defective in the ability to present antigen. Diabetes 1998. 47: 1212-1218.
    • (1998) Diabetes , vol.47 , pp. 1212-1218
    • Piganelli, J.D.1    Martin, T.2    Haskins, K.3
  • 5
    • 0033939014 scopus 로고    scopus 로고
    • Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: Elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice
    • Alleva, D. G., Pavlovich, R. P., Grant, C., Kaser, S. B. and Beller, D. I., Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice. Diabetes 2000. 49: 1106-1115.
    • (2000) Diabetes , vol.49 , pp. 1106-1115
    • Alleva, D.G.1    Pavlovich, R.P.2    Grant, C.3    Kaser, S.B.4    Beller, D.I.5
  • 6
    • 0027443570 scopus 로고
    • Hematopoietic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: Defective regulation of cytokine receptors and protein kinase C
    • Serreze, D. V., Gaedeke, J. W. and Leiter, E. H., Hematopoietic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: defective regulation of cytokine receptors and protein kinase C. Proc. Natl. Acad. Sci. USA 1993. 90: 9625-9629.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9625-9629
    • Serreze, D.V.1    Gaedeke, J.W.2    Leiter, E.H.3
  • 7
    • 0026451165 scopus 로고
    • B cells turn off virgin but not memory T cells
    • Fuchs, E. J. and Matzinger, P., B cells turn off virgin but not memory T cells. Science 1992. 258: 1156-1159.
    • (1992) Science , vol.258 , pp. 1156-1159
    • Fuchs, E.J.1    Matzinger, P.2
  • 8
    • 0027270850 scopus 로고
    • Parameters of tolerance induction by antigen targeted to B lymphocytes
    • Eynon, E. E. and Parker, D. C., Parameters of tolerance induction by antigen targeted to B lymphocytes. J. Immunol. 1993. 151: 2958-2964.
    • (1993) J. Immunol. , vol.151 , pp. 2958-2964
    • Eynon, E.E.1    Parker, D.C.2
  • 10
    • 0035085973 scopus 로고    scopus 로고
    • Development and function of diabetogenic T-cells in B-cell-deficient nonobese diabetic mice
    • Chiu, P. P., Serreze, D. V. and Danska, J. S., Development and function of diabetogenic T-cells in B-cell-deficient nonobese diabetic mice. Diabetes 2001. 50: 763-770.
    • (2001) Diabetes , vol.50 , pp. 763-770
    • Chiu, P.P.1    Serreze, D.V.2    Danska, J.S.3
  • 11
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh, S., May, M. J. and Kopp, E. B., NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 1998. 16: 225-260.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 13
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: New discoveries and insights
    • Baldwin, A. S., Jr., The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol. 1996. 14: 649-683.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 14
    • 0031586174 scopus 로고    scopus 로고
    • Identification and characterization of an IkappaB kinase
    • Regnier, C. H., Song, H. Y., Gao, X., Goeddel, D. V., Cao, Z. and Rothe, M., Identification and characterization of an IkappaB kinase. Cell 1997. 90: 373-383.
    • (1997) Cell , vol.90 , pp. 373-383
    • Regnier, C.H.1    Song, H.Y.2    Gao, X.3    Goeddel, D.V.4    Cao, Z.5    Rothe, M.6
  • 16
    • 0033106338 scopus 로고    scopus 로고
    • N-acetyl-l-cysteine inhibits primary human T cell responses at the dendritic cell level: Association with NF-kappaB inhibition
    • Verhasselt, V., Vanden Berghe, W., Vanderheyde, N., Willems, F., Haegeman, G. and Goldman, M., N-acetyl-l-cysteine inhibits primary human T cell responses at the dendritic cell level: association with NF-kappaB inhibition. J. Immunol. 1999. 162: 2569-2574.
    • (1999) J. Immunol. , vol.162 , pp. 2569-2574
    • Verhasselt, V.1    Vanden Berghe, W.2    Vanderheyde, N.3    Willems, F.4    Haegeman, G.5    Goldman, M.6
  • 18
    • 0036199656 scopus 로고    scopus 로고
    • Dendritic cell development and survival require distinct NF-kappaB subunits
    • Ouaaz, F., Arron, J., Zheng, Y., Choi, Y. and Beg, A. A., Dendritic cell development and survival require distinct NF-kappaB subunits. Immunity 2002. 16: 257-270.
    • (2002) Immunity , vol.16 , pp. 257-270
    • Ouaaz, F.1    Arron, J.2    Zheng, Y.3    Choi, Y.4    Beg, A.A.5
  • 19
    • 0028817585 scopus 로고
    • Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family
    • Weih, F., Carrasco, D., Durham, S. K., Barton, D. S., Rizzo, C. A., Ryseck, R. P., Lira, S. A. and Bravo, R., Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family. Cell 1995. 80: 331-340.
    • (1995) Cell , vol.80 , pp. 331-340
    • Weih, F.1    Carrasco, D.2    Durham, S.K.3    Barton, D.S.4    Rizzo, C.A.5    Ryseck, R.P.6    Lira, S.A.7    Bravo, R.8
  • 20
    • 0029143632 scopus 로고
    • Regulation of interleukin 12 p40 expression through an NF-kappa B half-site
    • Murphy, T. L., Cleveland, M. G., Kulesza, P, Magram, J. and Murphy, K. M., Regulation of interleukin 12 p40 expression through an NF-kappa B half-site. Mol. Cell. Biol. 1995. 15: 5258-5267.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 5258-5267
    • Murphy, T.L.1    Cleveland, M.G.2    Kulesza, P.3    Magram, J.4    Murphy, K.M.5
  • 21
    • 0028145676 scopus 로고
    • Insulin- specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice
    • Wegmann, D. R., Norbury-Glaser, M. and Daniel, D., Insulin- specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice. Eur. J. Immunol. 1994. 24: 1853-1857.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1853-1857
    • Wegmann, D.R.1    Norbury-Glaser, M.2    Daniel, D.3
  • 22
    • 0028914351 scopus 로고
    • Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice
    • Daniel, D., Gill, R. G., Schloot, N. and Wegmann, D., Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice. Eur. J. Immunol. 1995. 25: 1056-1062.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1056-1062
    • Daniel, D.1    Gill, R.G.2    Schloot, N.3    Wegmann, D.4
  • 23
    • 0030069688 scopus 로고    scopus 로고
    • Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)
    • Daniel, D. and Wegmann, D. R., Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23). Proc. Natl. Acad. Sci. USA 1996. 93: 956-960.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 956-960
    • Daniel, D.1    Wegmann, D.R.2
  • 24
    • 0032768786 scopus 로고    scopus 로고
    • Cellular immune response to phogrin in the NOD mouse: Cloned T cells cause destruction of islet transplants
    • Kelemen, K., Crawford, M. L., Gill, R. G., Hutton, J. C. and Wegmann, D., Cellular immune response to phogrin in the NOD mouse: cloned T cells cause destruction of islet transplants. Diabetes 1999. 48: 1529-1534.
    • (1999) Diabetes , vol.48 , pp. 1529-1534
    • Kelemen, K.1    Crawford, M.L.2    Gill, R.G.3    Hutton, J.C.4    Wegmann, D.5
  • 25
    • 0033499621 scopus 로고    scopus 로고
    • NOD mice are defective in proteasome production and activation of NF-kappaB
    • Hayashi, T. and Faustman, D., NOD mice are defective in proteasome production and activation of NF-kappaB. Mol. Cell. Biol. 1999. 19: 8646-8659.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 8646-8659
    • Hayashi, T.1    Faustman, D.2
  • 26
    • 0036680001 scopus 로고    scopus 로고
    • Measurement of IKK activity in primary rat T cells: Rapid activation and inactivation
    • Kupfer, R. and Scheinman, R. I., Measurement of IKK activity in primary rat T cells: rapid activation and inactivation. J. Immunol. Methods 2002. 266: 155-164.
    • (2002) J. Immunol. Methods , vol.266 , pp. 155-164
    • Kupfer, R.1    Scheinman, R.I.2
  • 27
    • 0035424898 scopus 로고    scopus 로고
    • Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase
    • Weaver, D. J., Jr., Poligone, B., Bui, T., Abdel-Motal, U. M., Baldwin, A. S., Jr. and Tisch, R., Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase. J. Immunol. 2001. 167: 1461-1468.
    • (2001) J. Immunol. , vol.167 , pp. 1461-1468
    • Weaver Jr., D.J.1    Poligone, B.2    Bui, T.3    Abdel-Motal, U.M.4    Baldwin Jr., A.S.5    Tisch, R.6
  • 28
    • 0021260621 scopus 로고
    • Non-obese-diabetic mice: Immune mechanisms of pancreatic beta-cell destruction
    • Kanazawa, Y., Komeda, K., Sato, S., Mori, S., Akanuma, K. and Takaku, F., Non-obese-diabetic mice: immune mechanisms of pancreatic beta-cell destruction. Diabetologia 1984. 27 Suppl: 113-115.
    • (1984) Diabetologia , vol.27 , Issue.SUPPL. , pp. 113-115
    • Kanazawa, Y.1    Komeda, K.2    Sato, S.3    Mori, S.4    Akanuma, K.5    Takaku, F.6
  • 29
  • 30
    • 0029826977 scopus 로고    scopus 로고
    • B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: Analysis of a new "speed congenic" stock of NOD.Ig mu null mice
    • Serreze, D. V., Chapman, H. D., Varnum, D. S., Hanson, M. S., Reifsnyder, P. C., Richard, S. D., Fleming, S. A., Leiter, E. H. and Shultz, L. D., B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice. J. Exp. Med. 1996. 184: 2049-2053.
    • (1996) J. Exp. Med. , vol.184 , pp. 2049-2053
    • Serreze, D.V.1    Chapman, H.D.2    Varnum, D.S.3    Hanson, M.S.4    Reifsnyder, P.C.5    Richard, S.D.6    Fleming, S.A.7    Leiter, E.H.8    Shultz, L.D.9
  • 31
    • 0032532294 scopus 로고    scopus 로고
    • B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice
    • Serreze, D. V., Fleming, S. A., Chapman, H. D., Richard, S. D., Leiter, E. H. and Tisch, R. M., B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice. J. Immunol. 1998. 161: 3912-3918.
    • (1998) J. Immunol. , vol.161 , pp. 3912-3918
    • Serreze, D.V.1    Fleming, S.A.2    Chapman, H.D.3    Richard, S.D.4    Leiter, E.H.5    Tisch, R.M.6
  • 32
    • 0030969531 scopus 로고    scopus 로고
    • B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice
    • Noorchashm, H., Noorchashm, N., Kern, J., Rostami, S. Y., Barker, C. F. and Naji, A., B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice. Diabetes 1997. 46: 941-946.
    • (1997) Diabetes , vol.46 , pp. 941-946
    • Noorchashm, H.1    Noorchashm, N.2    Kern, J.3    Rostami, S.Y.4    Barker, C.F.5    Naji, A.6
  • 35
    • 0026750296 scopus 로고
    • Breaking T cell tolerance with foreign and self co-immunogens. A study of autoimmune B and T cell epitopes of cytochrome c
    • Mamula, M. J., Lin, R. H., Janeway, C. A., Jr. and Hardin, J. A., Breaking T cell tolerance with foreign and self co-immunogens. A study of autoimmune B and T cell epitopes of cytochrome c. J. Immunol. 1992. 149: 789-795.
    • (1992) J. Immunol. , vol.149 , pp. 789-795
    • Mamula, M.J.1    Lin, R.H.2    Janeway Jr., C.A.3    Hardin, J.A.4
  • 36
    • 4544263445 scopus 로고
    • Flow cytometry
    • Coligan, J. E., Kruisbeek, A. M., Marguiles, D. H., Shevach, E. M. and Strober, W. (Eds.) John Wiley & Sons Section 5.3.6
    • Shevach, E. M., Flow cytometry. In Coligan, J. E., Kruisbeek, A. M., Marguiles, D. H., Shevach, E. M. and Strober, W. (Eds.) Current Protocols in Immunology. John Wiley & Sons 1994, Section 5.3.6.
    • (1994) Current Protocols in Immunology
    • Shevach, E.M.1
  • 37
    • 0033049571 scopus 로고    scopus 로고
    • The highly conserved beta-hairpin of the paired DNA-binding domain is required for assembly of Pax-Ets ternary complexes
    • Wheat, W., Fitzsimmons, D., Lennox, H., Krautkramer, S. R., Gentile, L. N., McIntosh, L. P. and Hagman, J., The highly conserved beta-hairpin of the paired DNA-binding domain is required for assembly of Pax-Ets ternary complexes. Mol. Cell. Biol. 1999. 19: 2231-2241.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 2231-2241
    • Wheat, W.1    Fitzsimmons, D.2    Lennox, H.3    Krautkramer, S.R.4    Gentile, L.N.5    McIntosh, L.P.6    Hagman, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.