Universally sloppy parameter sensitivities in systems biology models

PLoS Computational Biology

Volumn 3, Issue 10, 2007, Pages 1871-1878

  Gutenkunst, Ryan N ^a   Waterfall, Joshua J ^b   Casey, Fergal P ^c   Brown, Kevin S ^d   Myers, Christopher R ^b   Sethna, James P ^a  

^a Laboratory of Atomic and Solid State Physics and Sibley School of Mechanical and Aerospace Engineering   (United States)

^b Department of Obstetrics Gynecology   (United States)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY; EIGENVALUES AND EIGENFUNCTIONS;

BIOCHEMICAL PARAMETERS; COMPUTATIONAL MODELLING; FREE PARAMETERS; GROWTH FACTOR; IN-VIVO; MODEL DEVELOPMENT; MODERN BIOLOGY; PARAMETER SENSITIVITIES; SPECTRA'S; SYSTEMS BIOLOGY;

FORECASTING;

GROWTH FACTOR;

ACCURACY; ARTICLE; BIOLOGICAL MODEL; BIOLOGY; CHEMICAL ANALYSIS; PARAMETER; SENSITIVITY ANALYSIS; STATISTICAL DISTRIBUTION; STATISTICAL PARAMETERS; TIME SERIES ANALYSIS;

EID: 35748977901     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.0030189     Document Type: Article

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