-
1
-
-
67649660551
-
Redefining chronic viral infection
-
Virgin, H. W., Wherry, E. J. and Ahmed, R., Redefining chronic viral infection. Cell 2009. 138: 30-50.
-
(2009)
Cell
, vol.138
, pp. 30-50
-
-
Virgin, H.W.1
Wherry, E.J.2
Ahmed, R.3
-
2
-
-
45149111788
-
Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy
-
Peggs, K. S., Quezada, S. A. and Allison, J. P., Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy. Immunol. Rev. 2008. 224: 141-165.
-
(2008)
Immunol. Rev.
, vol.224
, pp. 141-165
-
-
Peggs, K.S.1
Quezada, S.A.2
Allison, J.P.3
-
3
-
-
1642577616
-
Immune surveillance against virus-induced tumors and nonrejectability of spontaneous tumors: Contrasting consequences of host versus tumor evolution
-
Klein, G. and Klein, E., Immune surveillance against virus-induced tumors and nonrejectability of spontaneous tumors: contrasting consequences of host versus tumor evolution. Proc. Natl. Acad. Sci. USA 1977. 74: 2121-2125.
-
(1977)
Proc. Natl. Acad. Sci. USA
, vol.74
, pp. 2121-2125
-
-
Klein, G.1
Klein, E.2
-
4
-
-
25844459154
-
NF-kappaB: Linking inflammation and immunity to cancer development and progression
-
Karin, M. and Greten, F. R., NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat. Rev. Immunol. 2005. 5: 749-759.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
5
-
-
35748960503
-
The adaptive immune response to sporadic cancer
-
Willimsky, G. and Blankenstein, T., The adaptive immune response to sporadic cancer. Immunol. Rev. 2007. 220: 102-112.
-
(2007)
Immunol. Rev.
, vol.220
, pp. 102-112
-
-
Willimsky, G.1
Blankenstein, T.2
-
6
-
-
70450015746
-
Does our current understanding of immune tolerance, autoimmunity, and immunosuppressive mechanisms facilitate the design of efficient cancer vaccines?
-
Sioud, M., Does our current understanding of immune tolerance, autoimmunity, and immunosuppressive mechanisms facilitate the design of efficient cancer vaccines? Scand. J. Immunol. 2009. 70: 516-525.
-
(2009)
Scand. J. Immunol.
, vol.70
, pp. 516-525
-
-
Sioud, M.1
-
7
-
-
33646804507
-
Mechanisms of immune evasion by tumors
-
Drake, C. G., Jaffee, E. and Pardoll, D. M., Mechanisms of immune evasion by tumors. Adv. Immunol. 2006. 90: 51-81.
-
(2006)
Adv. Immunol.
, vol.90
, pp. 51-81
-
-
Drake, C.G.1
Jaffee, E.2
Pardoll, D.M.3
-
8
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi, O. and Akira, S., Pattern recognition receptors and inflammation. Cell 2010. 140: 805-820.
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
9
-
-
66549123663
-
Natural killer and gammadelta T cells in haematological malignancies: Enhancing the immune effectors
-
Rey, J., Veuillen, C., Vey, N., Bouabdallah, R. and Olive, D., Natural killer and gammadelta T cells in haematological malignancies: enhancing the immune effectors. Trends Mol. Med. 2009. 15: 275-284.
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 275-284
-
-
Rey, J.1
Veuillen, C.2
Vey, N.3
Bouabdallah, R.4
Olive, D.5
-
10
-
-
0242491039
-
Negative selection and autoimmunity
-
Ohashi, P. S., Negative selection and autoimmunity. Curr. Opin. Immunol. 2003. 15: 668-676.
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 668-676
-
-
Ohashi, P.S.1
-
11
-
-
75649100153
-
Pattern recognition receptors of innate immunity and their application to tumor immunotherapy
-
Seya, T., Shime, H., Ebihara, T., Oshiumi, H. and Matsumoto, M., Pattern recognition receptors of innate immunity and their application to tumor immunotherapy. Cancer Sci. 2010. 101: 313-320.
-
(2010)
Cancer Sci.
, vol.101
, pp. 313-320
-
-
Seya, T.1
Shime, H.2
Ebihara, T.3
Oshiumi, H.4
Matsumoto, M.5
-
12
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
-
Ghiringhelli, F., Apetoh, L., Tesniere, A., Aymeric, L., Ma, Y., Ortiz, C., Vermaelen, K. et al., Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat. Med. 2009. 15: 1170-1178.
-
(2009)
Nat. Med.
, vol.15
, pp. 1170-1178
-
-
Ghiringhelli, F.1
Apetoh, L.2
Tesniere, A.3
Aymeric, L.4
Ma, Y.5
Ortiz, C.6
Vermaelen, K.7
-
13
-
-
37549032137
-
Immunological aspects of cancer chemotherapy
-
Zitvogel, L., Apetoh, L., Ghiringhelli, F. and Kroemer, G., Immunological aspects of cancer chemotherapy. Nat. Rev. Immunol. 2008. 8: 59-73.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 59-73
-
-
Zitvogel, L.1
Apetoh, L.2
Ghiringhelli, F.3
Kroemer, G.4
-
14
-
-
42449123606
-
Natural killer cell-directed therapies: Moving from unexpected results to successful strategies
-
Terme, M., Ullrich, E., Delahaye, N. F., Chaput, N. and Zitvogel, L., Natural killer cell-directed therapies: moving from unexpected results to successful strategies. Nat. Immunol. 2008. 9: 486-494.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 486-494
-
-
Terme, M.1
Ullrich, E.2
Delahaye, N.F.3
Chaput, N.4
Zitvogel, L.5
-
15
-
-
33846935228
-
Unique human tumor antigens: Immunobiology and use in clinical trials
-
Parmiani, G., De Filippo, A., Novellino, L. and Castelli, C., Unique human tumor antigens: immunobiology and use in clinical trials. J. Immunol. 2007. 178: 1975-1979. (Pubitemid 46233392)
-
(2007)
Journal of Immunology
, vol.178
, Issue.4
, pp. 1975-1979
-
-
Parmiani, G.1
De Filippo, A.2
Novellino, L.3
Castelli, C.4
-
16
-
-
33644816267
-
Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors
-
Teague, R. M., Sather, B. D., Sacks, J. A., Huang, M. Z., Dossett, M. L., Morimoto, J., Tan, X. et al., Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors. Nat. Med. 2006. 12: 335-341.
-
(2006)
Nat. Med.
, vol.12
, pp. 335-341
-
-
Teague, R.M.1
Sather, B.D.2
Sacks, J.A.3
Huang, M.Z.4
Dossett, M.L.5
Morimoto, J.6
Tan, X.7
-
17
-
-
44849084026
-
A study of T cell tolerance to the tumor-associated antigen MDM2: Cytokines can restore antigen responsiveness, but not high avidity T cell function
-
Bendle, G. M., Xue, S. A., Holler, A. and Stauss, H. J., A study of T cell tolerance to the tumor-associated antigen MDM2: cytokines can restore antigen responsiveness, but not high avidity T cell function. PLoS One 2007. 2: e353.
-
(2007)
PLoS One
, vol.2
-
-
Bendle, G.M.1
Xue, S.A.2
Holler, A.3
Stauss, H.J.4
-
18
-
-
67349193717
-
Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies
-
Pellegrini, M., Calzascia, T., Elford, A. R., Shahinian, A., Lin, A. E., Dissanayake, D., Dhanji, S. et al., Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies. Nat. Med. 2009. 15: 528-536.
-
(2009)
Nat. Med.
, vol.15
, pp. 528-536
-
-
Pellegrini, M.1
Calzascia, T.2
Elford, A.R.3
Shahinian, A.4
Lin, A.E.5
Dissanayake, D.6
Dhanji, S.7
-
19
-
-
41149097574
-
Adoptive cell transfer: A clinical path to effective cancer immunotherapy
-
Rosenberg, S. A., Restifo, N. P., Yang, J. C., Morgan, R. A. and Dudley, M. E., Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat. Rev. Cancer 2008. 8: 299-308.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 299-308
-
-
Rosenberg, S.A.1
Restifo, N.P.2
Yang, J.C.3
Morgan, R.A.4
Dudley, M.E.5
-
20
-
-
58149213871
-
Behavior of immune players in the tumor microenvironment
-
Pittet, M. J., Behavior of immune players in the tumor microenvironment. Curr. Opin. Oncol. 2009. 21: 53-59.
-
(2009)
Curr. Opin. Oncol.
, vol.21
, pp. 53-59
-
-
Pittet, M.J.1
-
21
-
-
33947259319
-
Immunosuppressive strategies that are mediated by tumor cells
-
Rabinovich, G. A., Gabrilovich, D. and Sotomayor, E. M., Immunosuppressive strategies that are mediated by tumor cells. Annu. Rev. Immunol. 2007. 25: 267-296.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 267-296
-
-
Rabinovich, G.A.1
Gabrilovich, D.2
Sotomayor, E.M.3
-
22
-
-
47949090079
-
The role of myeloid cells in the promotion of tumour angiogenesis
-
Murdoch, C., Muthana, M., Coffelt, S. B. and Lewis, C. E., The role of myeloid cells in the promotion of tumour angiogenesis. Nat. Rev. Cancer 2008. 8: 618-631.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 618-631
-
-
Murdoch, C.1
Muthana, M.2
Coffelt, S.B.3
Lewis, C.E.4
-
23
-
-
47249102067
-
CD4+ T-regulatory cells: Toward therapy for human diseases
-
Allan, S. E., Broady, R., Gregori, S., Himmel, M. E., Locke, N., Roncarolo, M. G., Bacchetta, R. and Levings, M. K., CD4+ T-regulatory cells: toward therapy for human diseases. Immunol. Rev. 2008. 223: 391-421.
-
(2008)
Immunol. Rev.
, vol.223
, pp. 391-421
-
-
Allan, S.E.1
Broady, R.2
Gregori, S.3
Himmel, M.E.4
Locke, N.5
Roncarolo, M.G.6
Bacchetta, R.7
Levings, M.K.8
-
24
-
-
22344432319
-
Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia
-
Ruprecht, C. R., Gattorno, M., Ferlito, F., Gregorio, A., Martini, A., Lanzavecchia, A. and Sallusto, F., Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia. J. Exp. Med. 2005. 201: 1793-1803.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1793-1803
-
-
Ruprecht, C.R.1
Gattorno, M.2
Ferlito, F.3
Gregorio, A.4
Martini, A.5
Lanzavecchia, A.6
Sallusto, F.7
-
25
-
-
67449168109
-
IL-15 renders conventional lymphocytes resistant to suppressive functions of regulatory T cells through activation of the phosphatidylinositol 3-kinase pathway
-
Ben Ahmed, M., Belhadj Hmida, N., Moes, N., Buyse, S., Abdeladhim, M., Louzir, H. and Cerf-Bensussan, N., IL-15 renders conventional lymphocytes resistant to suppressive functions of regulatory T cells through activation of the phosphatidylinositol 3-kinase pathway. J. Immunol. 2009. 182: 6763-6770.
-
(2009)
J. Immunol.
, vol.182
, pp. 6763-6770
-
-
Ben Ahmed, M.1
Belhadj Hmida, N.2
Moes, N.3
Buyse, S.4
Abdeladhim, M.5
Louzir, H.6
Cerf-Bensussan, N.7
-
26
-
-
70449726875
-
Harnessing the physiology of lymphopenia to support adoptive immunotherapy in lymphoreplete hosts
-
Cui, Y., Zhang, H., Meadors, J., Poon, R., Guimond, M. and Mackall, C. L., Harnessing the physiology of lymphopenia to support adoptive immunotherapy in lymphoreplete hosts. Blood 2009. 114: 3831-3840.
-
(2009)
Blood
, vol.114
, pp. 3831-3840
-
-
Cui, Y.1
Zhang, H.2
Meadors, J.3
Poon, R.4
Guimond, M.5
Mackall, C.L.6
-
27
-
-
66849135251
-
Cancer immunotherapy: Co-stimulatory agonists and co-inhibitory antagonists
-
Peggs, K. S., Quezada, S. A. and Allison, J. P., Cancer immunotherapy: co-stimulatory agonists and co-inhibitory antagonists. Clin. Exp. Immunol. 2009. 157: 9-19.
-
(2009)
Clin. Exp. Immunol.
, vol.157
, pp. 9-19
-
-
Peggs, K.S.1
Quezada, S.A.2
Allison, J.P.3
-
28
-
-
33645837467
-
Molecular immunological approaches to biotherapy of human cancers - A review, hypothesis and implications
-
Becker, Y., Molecular immunological approaches to biotherapy of human cancers - a review, hypothesis and implications. Anticancer Res. 2006. 26: 1113-1134.
-
(2006)
Anticancer Res.
, vol.26
, pp. 1113-1134
-
-
Becker, Y.1
-
29
-
-
41149132390
-
Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape
-
Katz, J. B., Muller, A. J. and Prendergast, G. C., Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape. Immunol. Rev. 2008. 222: 206-221.
-
(2008)
Immunol. Rev.
, vol.222
, pp. 206-221
-
-
Katz, J.B.1
Muller, A.J.2
Prendergast, G.C.3
-
30
-
-
67649432744
-
Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: Can we see the wood for the trees?
-
Lob, S., Konigsrainer, A., Rammensee, H. G., Opelz, G. and Terness, P., Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees? Nat. Rev. Cancer 2009. 9: 445-452.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 445-452
-
-
Lob, S.1
Konigsrainer, A.2
Rammensee, H.G.3
Opelz, G.4
Terness, P.5
-
31
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
Yu, H., Pardoll, D. and Jove, R., STATs in cancer inflammation and immunity: a leading role for STAT3. Nat. Rev. Cancer 2009. 9: 798-809.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
32
-
-
33846465547
-
Immunostimulatory monoclonal antibodies for cancer therapy
-
Melero, I., Hervas-Stubbs, S., Glennie, M., Pardoll, D. M. and Chen, L., Immunostimulatory monoclonal antibodies for cancer therapy. Nat. Rev. Cancer 2007. 7: 95-106.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 95-106
-
-
Melero, I.1
Hervas-Stubbs, S.2
Glennie, M.3
Pardoll, D.M.4
Chen, L.5
-
33
-
-
70349560862
-
Cytokines as adjuvants for vaccine and cellular therapies for cancer
-
Capitini, C. M., Fry, T. J. and Mackall, C. L., Cytokines as adjuvants for vaccine and cellular therapies for cancer. Am. J. Immunol. 2009. 5: 65-83.
-
(2009)
Am. J. Immunol.
, vol.5
, pp. 65-83
-
-
Capitini, C.M.1
Fry, T.J.2
Mackall, C.L.3
-
34
-
-
68149155982
-
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
-
Peggs, K. S., Quezada, S. A., Chambers, C. A., Korman, A. J. and Allison, J. P., Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. J. Exp. Med. 2009. 206: 1717-1725.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1717-1725
-
-
Peggs, K.S.1
Quezada, S.A.2
Chambers, C.A.3
Korman, A.J.4
Allison, J.P.5
-
35
-
-
36849043810
-
The role of E3 ligases in autoimmunity and the regulation of autoreactive T cells
-
Lin, A. E. and Mak, T.W., The role of E3 ligases in autoimmunity and the regulation of autoreactive T cells. Curr. Opin. Immunol. 2007. 19: 665-673.
-
(2007)
Curr. Opin. Immunol.
, vol.19
, pp. 665-673
-
-
Lin, A.E.1
Mak, T.W.2
-
36
-
-
34249660614
-
SOCS proteins, cytokine signalling and immune regulation
-
Yoshimura, A., Naka, T. and Kubo, M., SOCS proteins, cytokine signalling and immune regulation. Nat. Rev. Immunol. 2007. 7: 454-465.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 454-465
-
-
Yoshimura, A.1
Naka, T.2
Kubo, M.3
-
37
-
-
38549157070
-
NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins
-
Huang,G. N., Huso, D. L., Bouyain, S., Tu, J., McCorkell, K. A., May, M. J., Zhu, Y. et al., NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins. Science 2008. 319: 476-481.
-
(2008)
Science
, vol.319
, pp. 476-481
-
-
Huang, G.N.1
Huso, D.L.2
Bouyain, S.3
Tu, J.4
McCorkell, K.A.5
May, M.J.6
Zhu, Y.7
-
38
-
-
33750093594
-
T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha
-
Zha, Y., Marks, R., Ho, A. W., Peterson, A. C., Janardhan, S., Brown, I., Praveen, K. et al., T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha. Nat. Immunol. 2006. 7: 1166-1173.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1166-1173
-
-
Zha, Y.1
Marks, R.2
Ho, A.W.3
Peterson, A.C.4
Janardhan, S.5
Brown, I.6
Praveen, K.7
-
39
-
-
18244375249
-
Egr-2 and Egr-3 are negative regulators of T cell activation
-
Safford, M., Collins, S., Lutz, M. A., Allen, A., Huang, C. T., Kowalski, J., Blackford, A. et al., Egr-2 and Egr-3 are negative regulators of T cell activation. Nat. Immunol. 2005. 6: 472-480.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 472-480
-
-
Safford, M.1
Collins, S.2
Lutz, M.A.3
Allen, A.4
Huang, C.T.5
Kowalski, J.6
Blackford, A.7
-
40
-
-
33645064841
-
IL-7 promotes T cell proliferation through destabilization of p27Kip1
-
Li, W. Q., Jiang, Q., Aleem, E., Kaldis, P., Khaled, A. R. and Durum, S. K., IL-7 promotes T cell proliferation through destabilization of p27Kip1. J. Exp. Med. 2006. 203: 573-582.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 573-582
-
-
Li, W.Q.1
Jiang, Q.2
Aleem, E.3
Kaldis, P.4
Khaled, A.R.5
Durum, S.K.6
-
41
-
-
42949131224
-
CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity
-
Calzascia, T., Pellegrini, M., Lin, A., Garza, K. M., Elford, A. R., Shahinian, A., Ohashi, P. S. and Mak, T. W., CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity. Proc. Natl. Acad. Sci. USA 2008. 105: 2999-3004.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 2999-3004
-
-
Calzascia, T.1
Pellegrini, M.2
Lin, A.3
Garza, K.M.4
Elford, A.R.5
Shahinian, A.6
Ohashi, P.S.7
Mak, T.W.8
-
42
-
-
33750321707
-
Interferons, immunity and cancer immunoediting
-
Dunn, G. P., Koebel, C. M. and Schreiber, R. D., Interferons, immunity and cancer immunoediting. Nat. Rev. Immunol. 2006. 6: 836-848.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 836-848
-
-
Dunn, G.P.1
Koebel, C.M.2
Schreiber, R.D.3
-
43
-
-
18244371047
-
Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD81 memory cell pool
-
Melchionda, F., Fry, T. J., Milliron, M. J., McKirdy, M. A., Tagaya, Y. and Mackall, C. L., Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD81 memory cell pool. J. Clin. Invest. 2005. 115: 1177-1187.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1177-1187
-
-
Melchionda, F.1
Fry, T.J.2
Milliron, M.J.3
McKirdy, M.A.4
Tagaya, Y.5
Mackall, C.L.6
-
44
-
-
46949105036
-
Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets
-
Sportes, C., Hakim, F. T., Memon, S. A., Zhang, H., Chua, K. S., Brown, M. R., Fleisher, T. A. et al., Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets. J. Exp. Med. 2008. 205: 1701-1714.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1701-1714
-
-
Sportes, C.1
Hakim, F.T.2
Memon, S.A.3
Zhang, H.4
Chua, K.S.5
Brown, M.R.6
Fleisher, T.A.7
-
45
-
-
58149334990
-
Can NK cells be a therapeutic target in human cancer?
-
Chan, C. J., Andrews, D. M. and Smyth, M. J., Can NK cells be a therapeutic target in human cancer? Eur. J. Immunol. 2008. 38: 2964-2968.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 2964-2968
-
-
Chan, C.J.1
Andrews, D.M.2
Smyth, M.J.3
-
46
-
-
34250634403
-
A potential role for epigenetic modulatory drugs in the enhancement of cancer/germ-line antigen vaccine efficacy
-
Karpf, A. R., A potential role for epigenetic modulatory drugs in the enhancement of cancer/germ-line antigen vaccine efficacy. Epigenetics 2006. 1: 116-120.
-
(2006)
Epigenetics
, vol.1
, pp. 116-120
-
-
Karpf, A.R.1
-
47
-
-
33646704729
-
Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy
-
Reits, E. A., Hodge, J. W., Herberts, C. A., Groothuis, T. A., Chakraborty, M., Wansley, E. K. et al., Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. J. Exp. Med. 2006. 203: 1259-1271.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1259-1271
-
-
Reits, E.A.1
Hodge, J.W.2
Herberts, C.A.3
Groothuis, T.A.4
Chakraborty, M.5
Wansley, E.K.6
-
48
-
-
77951614830
-
Monoclonal antibodies: Versatile platforms for cancer immunotherapy
-
Weiner, L. M., Surana, R. and Wang, S., Monoclonal antibodies: versatile platforms for cancer immunotherapy. Nat. Rev. Immunol. 2010. 10: 317-327.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 317-327
-
-
Weiner, L.M.1
Surana, R.2
Wang, S.3
-
49
-
-
73849140105
-
Immune modulation with interleukin-21
-
Bhave, N. S. and Carson, W. E., 3rd., Immune modulation with interleukin-21. Ann. NY Acad. Sci. 2009. 1182: 39-46.
-
(2009)
Ann. NY Acad. Sci.
, vol.1182
, pp. 39-46
-
-
Bhave, N.S.1
Carson III, W.E.2
-
50
-
-
67649976634
-
Functions of gammaC cytokines in immune homeostasis: Current and potential clinical applications
-
Overwijk, W. W. and Schluns, K. S., Functions of gammaC cytokines in immune homeostasis: current and potential clinical applications. Clin. Immunol. 2009. 132: 153-165.
-
(2009)
Clin. Immunol.
, vol.132
, pp. 153-165
-
-
Overwijk, W.W.1
Schluns, K.S.2
-
51
-
-
67649876115
-
New insights into the regulation of T cells by gamma(c) family cytokines
-
Rochman, Y., Spolski, R. and Leonard, W. J., New insights into the regulation of T cells by gamma(c) family cytokines. Nat. Rev. Immunol. 2009. 9: 480-490.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 480-490
-
-
Rochman, Y.1
Spolski, R.2
Leonard, W.J.3
-
52
-
-
8344239652
-
A review of recent findings involving interleukin-2-based cancer therapy
-
Eklund, J. W. and Kuzel, T. M., A review of recent findings involving interleukin-2-based cancer therapy. Curr. Opin. Oncol. 2004. 16: 542-546.
-
(2004)
Curr. Opin. Oncol.
, vol.16
, pp. 542-546
-
-
Eklund, J.W.1
Kuzel, T.M.2
-
53
-
-
33745224089
-
Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells
-
Williams, M. A., Tyznik, A. J. and Bevan, M. J., Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells. Nature 2006. 441: 890-893.
-
(2006)
Nature
, vol.441
, pp. 890-893
-
-
Williams, M.A.1
Tyznik, A.J.2
Bevan, M.J.3
-
54
-
-
4544241811
-
Tolerance, not immunity, crucially depends on IL-2
-
Malek, T. R. and Bayer, A. L., Tolerance, not immunity, crucially depends on IL-2. Nat. Rev. Immunol. 2004. 4: 665-674.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 665-674
-
-
Malek, T.R.1
Bayer, A.L.2
-
55
-
-
30744458573
-
Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells
-
Zhang, H., Chua, K. S., Guimond, M., Kapoor, V., Brown, M. V., Fleisher, T. A. and Long, L. M. Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells. Nat. Med. 2005. 11: 1238-1243.
-
(2005)
Nat. Med.
, vol.11
, pp. 1238-1243
-
-
Zhang, H.1
Chua, K.S.2
Guimond, M.3
Kapoor, V.4
Brown, M.V.5
Fleisher, T.A.6
Long, L.M.7
-
56
-
-
77953297342
-
Expansion of regulatory T cells via IL-2/anti-IL-2 mAb complexes suppresses experimental myasthenia
-
Liu, R., Zhou, Q., La Cava, A., Campagnolo, D. I., Van Kaer, L. and Shi, F. D., Expansion of regulatory T cells via IL-2/anti-IL-2 mAb complexes suppresses experimental myasthenia. Eur. J. Immunol. 2010. 40: 1577-1589.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 1577-1589
-
-
Liu, R.1
Zhou, Q.2
La Cava, A.3
Campagnolo, D.I.4
Van Kaer, L.5
Shi, F.D.6
-
57
-
-
33645465526
-
Selective stimulation of T cell subsets with antibody-cytokine immune complexes
-
Boyman, O., Kovar, M., Rubinstein, M. P., Surh, C. D. and Sprent, J., Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science 2006. 311: 1924-1927.
-
(2006)
Science
, vol.311
, pp. 1924-1927
-
-
Boyman, O.1
Kovar, M.2
Rubinstein, M.P.3
Surh, C.D.4
Sprent, J.5
-
58
-
-
33746547247
-
The biology of interleukin-2 and interleukin-15: Implications for cancer therapy and vaccine design
-
Waldmann, T. A., The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat. Rev. Immunol. 2006. 6: 595-601.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 595-601
-
-
Waldmann, T.A.1
-
59
-
-
0036826914
-
IL-15Ralpha recycles and presents IL-15 in trans to neighboring cells
-
DOI 10.1016/S1074-7613(02)00429-6
-
Dubois, S., Mariner, J., Waldmann, T. A. and Tagaya, Y., IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells. Immunity 2002. 17: 537-547. (Pubitemid 35351500)
-
(2002)
Immunity
, vol.17
, Issue.5
, pp. 537-547
-
-
Dubois, S.1
Mariner, J.2
Waldmann, T.A.3
Tagaya, Y.4
-
60
-
-
0034610970
-
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
-
Kennedy, M. K., Glaccum, M., Brown, S. N., Butz, E. A., Viney, J. L., Embers, M., Matsuki, N. et al., Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J. Exp. Med. 2000. 191: 771-780.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 771-780
-
-
Kennedy, M.K.1
Glaccum, M.2
Brown, S.N.3
Butz, E.A.4
Viney, J.L.5
Embers, M.6
Matsuki, N.7
-
61
-
-
0032211699
-
IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
-
Lodolce, J. P., Boone, D. L., Chai, S., Swain, R. E., Dassopoulos, T., Trettin, S. and Ma, A., IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998. 9: 669-676.
-
(1998)
Immunity
, vol.9
, pp. 669-676
-
-
Lodolce, J.P.1
Boone, D.L.2
Chai, S.3
Swain, R.E.4
Dassopoulos, T.5
Trettin, S.6
Ma, A.7
-
62
-
-
30044448268
-
Interleukin 15 controls the generation of the restricted T cell receptor repertoire of gamma delta intestinal intraepithelial lymphocytes
-
Zhao, H., Nguyen, H. and Kang, J., Interleukin 15 controls the generation of the restricted T cell receptor repertoire of gamma delta intestinal intraepithelial lymphocytes. Nat. Immunol. 2005. 6: 1263-1271.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1263-1271
-
-
Zhao, H.1
Nguyen, H.2
Kang, J.3
-
63
-
-
50849131938
-
Trans-presentation of IL-15 dictates IFN-producing killer dendritic cells effector functions
-
Ullrich, E., Bonmort, M., Mignot, G., Jacobs, B., Bosisio, D., Sozzani, S., Jalil, A. et al., Trans-presentation of IL-15 dictates IFN-producing killer dendritic cells effector functions. J. Immunol. 2008. 180: 7887-7897.
-
(2008)
J. Immunol.
, vol.180
, pp. 7887-7897
-
-
Ullrich, E.1
Bonmort, M.2
Mignot, G.3
Jacobs, B.4
Bosisio, D.5
Sozzani, S.6
Jalil, A.7
-
64
-
-
10744226452
-
IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells
-
Klebanoff, C. A., Finkelstein, S. E., Surman, D. R., Lichtman, M. K., Gattinoni, L., Theoret, M. R., Grewal, N. et al., IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells. Proc. Natl. Acad. Sci. USA 2004. 101: 1969-1974.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1969-1974
-
-
Klebanoff, C.A.1
Finkelstein, S.E.2
Surman, D.R.3
Lichtman, M.K.4
Gattinoni, L.5
Theoret, M.R.6
Grewal, N.7
-
65
-
-
42349091974
-
Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells
-
Epardaud, M., Elpek, K. G., Rubinstein, M. P., Yonekura, A. R., Bellemare-Pelletier, A., Bronson, R., Hamerman, J. A. et al., Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells. Cancer Res. 2008. 68: 2972-2983.
-
(2008)
Cancer Res.
, vol.68
, pp. 2972-2983
-
-
Epardaud, M.1
Elpek, K.G.2
Rubinstein, M.P.3
Yonekura, A.R.4
Bellemare-Pelletier, A.5
Bronson, R.6
Hamerman, J.A.7
-
66
-
-
7444252881
-
Failed adoptive immunotherapy with tumor-specific T cells: Reversal with low-dose interleukin 15 but not low-dose interleukin 2
-
Roychowdhury, S., May, K. F., Jr., Tzou, K. S., Lin, T., Bhatt, D., Freud, A. G., Guimond, M. et al., Failed adoptive immunotherapy with tumor-specific T cells: reversal with low-dose interleukin 15 but not low-dose interleukin 2. Cancer Res. 2004. 64: 8062-8067.
-
(2004)
Cancer Res.
, vol.64
, pp. 8062-8067
-
-
Roychowdhury, S.1
May Jr., K.F.2
Tzou, K.S.3
Lin, T.4
Bhatt, D.5
Freud, A.G.6
Guimond, M.7
-
67
-
-
33750335080
-
Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo
-
Stoklasek, T. A., Schluns, K. S. and Lefrancois, L., Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo. J. Immunol. 2006. 177: 6072-6080. (Pubitemid 44628822)
-
(2006)
Journal of Immunology
, vol.177
, Issue.9
, pp. 6072-6080
-
-
Stoklasek, T.A.1
Schluns, K.S.2
Lefrancois, L.3
-
68
-
-
0037159687
-
A critical role for IL-21 in regulating immunoglobulin production
-
Ozaki, K., Spolski, R., Feng, C. G., Qi, C. F., Cheng, J., Sher, A., Morse, H. C., 3rd. et al., A critical role for IL-21 in regulating immunoglobulin production. Science 2002. 298: 1630-1634.
-
(2002)
Science
, vol.298
, pp. 1630-1634
-
-
Ozaki, K.1
Spolski, R.2
Feng, C.G.3
Qi, C.F.4
Cheng, J.5
Sher, A.6
Morse III, H.C.7
-
69
-
-
39549101010
-
Interleukin-21 activates human natural killer cells and modulates their surface receptor expression
-
Skak, K., Frederiksen, K. S. and Lundsgaard, D., Interleukin-21 activates human natural killer cells and modulates their surface receptor expression. Immunology 2008. 123: 575-583.
-
(2008)
Immunology
, vol.123
, pp. 575-583
-
-
Skak, K.1
Frederiksen, K.S.2
Lundsgaard, D.3
-
70
-
-
18344394955
-
IL-21 limits NK cell responses and promotes antigen-specific T cell activation: A mediator of the transition from innate to adaptive immunity
-
Kasaian, M. T., Whitters, M. J., Carter, L. L., Lowe, L. D., Jussif, J. M., Deng, B., Johnson, K. A. et al., IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity. Immunity 2002. 16: 559-569.
-
(2002)
Immunity
, vol.16
, pp. 559-569
-
-
Kasaian, M.T.1
Whitters, M.J.2
Carter, L.L.3
Lowe, L.D.4
Jussif, J.M.5
Deng, B.6
Johnson, K.A.7
-
71
-
-
0034597789
-
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
-
Parrish-Novak, J., Dillon, S. R., Nelson, A., Hammond, A., Sprecher, C., Gross, J. A., Johnston, J. et al., Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 2000. 408: 57-63.
-
(2000)
Nature
, vol.408
, pp. 57-63
-
-
Parrish-Novak, J.1
Dillon, S.R.2
Nelson, A.3
Hammond, A.4
Sprecher, C.5
Gross, J.A.6
Johnston, J.7
-
72
-
-
19944434230
-
Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function
-
Zeng, R., Spolski, R., Finkelstein, S. E., Oh, S., Kovanen, P. E., Hinrichs, C. S., Pise-Masison, C. A. et al., Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function. J. Exp. Med. 2005. 201: 139-148.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 139-148
-
-
Zeng, R.1
Spolski, R.2
Finkelstein, S.E.3
Oh, S.4
Kovanen, P.E.5
Hinrichs, C.S.6
Pise-Masison, C.A.7
-
73
-
-
34848927882
-
IL-21 synergizes with IL-7 to augment expansion and anti-tumor function of cytotoxic T cells
-
Liu, S., Lizee, G., Lou, Y., Liu, C., Overwijk,W.W.,Wang, G. and Hwu, P., IL-21 synergizes with IL-7 to augment expansion and anti-tumor function of cytotoxic T cells. Int. Immunol. 2007. 19: 1213-1221.
-
(2007)
Int. Immunol.
, vol.19
, pp. 1213-1221
-
-
Liu, S.1
Lizee, G.2
Lou, Y.3
Liu, C.4
Overwijk, W.W.5
Wang, G.6
Hwu, P.7
-
74
-
-
48149096869
-
IL-21 induces in vivo immune activation of NK cells and CD8(+) T cells in patients with metastatic melanoma and renal cell carcinoma
-
Frederiksen, K. S., Lundsgaard, D., Freeman, J. A., Hughes, S. D., Holm, T. L., Skrumsager, B. K., Petri, A. et al., IL-21 induces in vivo immune activation of NK cells and CD8(+) T cells in patients with metastatic melanoma and renal cell carcinoma. Cancer Immunol. Immunother. 2008. 57: 1439-1449.
-
(2008)
Cancer Immunol. Immunother.
, vol.57
, pp. 1439-1449
-
-
Frederiksen, K.S.1
Lundsgaard, D.2
Freeman, J.A.3
Hughes, S.D.4
Holm, T.L.5
Skrumsager, B.K.6
Petri, A.7
-
75
-
-
67649203681
-
A vital role for interleukin-21 in the control of a chronic viral infection
-
Yi, J. S., Du, M. and Zajac, A. J., A vital role for interleukin-21 in the control of a chronic viral infection. Science 2009. 324: 1572-1576.
-
(2009)
Science
, vol.324
, pp. 1572-1576
-
-
Yi, J.S.1
Du, M.2
Zajac, A.J.3
-
76
-
-
67649234772
-
IL-21R on T cells is critical for sustained functionality and control of chronic viral infection
-
Frohlich, A., Kisielow, J., Schmitz, I., Freigang, S., Shamshiev, A. T., Weber, J., Marsland, B. J. et al., IL-21R on T cells is critical for sustained functionality and control of chronic viral infection. Science 2009. 324: 1576-1580.
-
(2009)
Science
, vol.324
, pp. 1576-1580
-
-
Frohlich, A.1
Kisielow, J.2
Schmitz, I.3
Freigang, S.4
Shamshiev, A.T.5
Weber, J.6
Marsland, B.J.7
-
77
-
-
67649217469
-
IL-21 is required to control chronic viral infection
-
Elsaesser, H., Sauer, K. and Brooks, D. G., IL-21 is required to control chronic viral infection. Science 2009. 324: 1569-1572.
-
(2009)
Science
, vol.324
, pp. 1569-1572
-
-
Elsaesser, H.1
Sauer, K.2
Brooks, D.G.3
-
78
-
-
2542595794
-
IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: Comparative evaluation of IL-2, IL-15, and IL-21
-
Moroz, A., Eppolito, C., Li, Q., Tao, J., Clegg, C. H. and Shrikant, P. A., IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: comparative evaluation of IL-2, IL-15, and IL-21. J. Immunol. 2004. 173: 900-909.
-
(2004)
J. Immunol.
, vol.173
, pp. 900-909
-
-
Moroz, A.1
Eppolito, C.2
Li, Q.3
Tao, J.4
Clegg, C.H.5
Shrikant, P.A.6
-
79
-
-
0038784488
-
IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-gamma
-
Ma, H. L., Whitters, M. J., Konz, R. F., Senices, M., Young, D. A., Grusby, M. J., Collins, M. and Dunussi-Joannopoulos, K., IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-gamma. J. Immunol. 2003. 171: 608-615. (Pubitemid 36871368)
-
(2003)
Journal of Immunology
, vol.171
, Issue.2
, pp. 608-615
-
-
Ma, H.-L.1
Whitters, M.J.2
Konz, R.F.3
Senices, M.4
Young, D.A.5
Grusby, M.J.6
Collins, M.7
Dunussi-Joannopoulos, K.8
-
80
-
-
0347320749
-
In vivo antitumor activity of interleukin 21 mediated by natural killer cells
-
Wang, G., Tschoi, M., Spolski, R., Lou, Y., Ozaki, K., Feng, C., Kim, G. et al., In vivo antitumor activity of interleukin 21 mediated by natural killer cells. Cancer Res. 2003. 63: 9016-9022.
-
(2003)
Cancer Res.
, vol.63
, pp. 9016-9022
-
-
Wang, G.1
Tschoi, M.2
Spolski, R.3
Lou, Y.4
Ozaki, K.5
Feng, C.6
Kim, G.7
-
81
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn, T., Bettelli, E., Gao, W., Awasthi, A., Jager, A., Strom, T. B., Oukka, M. and Kuchroo, V. K., IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 2007. 448: 484-487.
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
Awasthi, A.4
Jager, A.5
Strom, T.B.6
Oukka, M.7
Kuchroo, V.K.8
-
82
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva, R., Yang, X. O., Martinez, G., Zhang, Y., Panopoulos, A. D., Ma, L., Schluns, K. et al., Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 2007. 448: 480-483.
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
Yang, X.O.2
Martinez, G.3
Zhang, Y.4
Panopoulos, A.D.5
Ma, L.6
Schluns, K.7
-
83
-
-
70449530422
-
T helper 17 cells promote cytotoxic T cell activation in tumor immunity
-
Martin-Orozco, N., Muranski, P., Chung, Y., Yang, X. O., Yamazaki, T., Lu, S., Hwu, P. et al., T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity 2009. 31: 787-798.
-
(2009)
Immunity
, vol.31
, pp. 787-798
-
-
Martin-Orozco, N.1
Muranski, P.2
Chung, Y.3
Yang, X.O.4
Yamazaki, T.5
Lu, S.6
Hwu, P.7
-
84
-
-
47649122633
-
Tumor-specific Th17-polarized cells eradicate large established melanoma
-
Muranski, P., Boni, A., Antony, P. A., Cassard, L., Irvine, K. R., Kaiser, A., Paulos, C. M. et al., Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood 2008. 112: 362-373.
-
(2008)
Blood
, vol.112
, pp. 362-373
-
-
Muranski, P.1
Boni, A.2
Antony, P.A.3
Cassard, L.4
Irvine, K.R.5
Kaiser, A.6
Paulos, C.M.7
-
85
-
-
42949139835
-
Phase I study of recombinant interleukin-21 in patients with metastatic melanoma and renal cell carcinoma
-
Thompson, J. A., Curti, B. D., Redman, B. G., Bhatia, S., Weber, J. S., Agarwala, S. S., Sievers, E. L. et al., Phase I study of recombinant interleukin-21 in patients with metastatic melanoma and renal cell carcinoma. J. Clin. Oncol. 2008. 26: 2034-2039.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2034-2039
-
-
Thompson, J.A.1
Curti, B.D.2
Redman, B.G.3
Bhatia, S.4
Weber, J.S.5
Agarwala, S.S.6
Sievers, E.L.7
-
86
-
-
63449095686
-
Clinical and biological efficacy of recombinant human interleukin-21 in patients with stage IV malignant melanoma without prior treatment: A phase IIa trial
-
Davis, I. D., Brady, B., Kefford, R. F., Millward, M., Cebon, J., Skrumsager, B. K., Mouritzen, U. et al., Clinical and biological efficacy of recombinant human interleukin-21 in patients with stage IV malignant melanoma without prior treatment: a phase IIa trial. Clin. Cancer Res. 2009. 15: 2123-2129.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 2123-2129
-
-
Davis, I.D.1
Brady, B.2
Kefford, R.F.3
Millward, M.4
Cebon, J.5
Skrumsager, B.K.6
Mouritzen, U.7
-
87
-
-
34250761481
-
An open-label, two-arm, phase I trial of recombinant human interleukin-21 in patients with metastatic melanoma
-
Davis, I. D., Skrumsager, B. K., Cebon, J., Nicholaou, T., Barlow, J. W., Moller, N. P., Skak, K. et al., An open-label, two-arm, phase I trial of recombinant human interleukin-21 in patients with metastatic melanoma. Clin. Cancer Res. 2007. 13: 3630-3636.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 3630-3636
-
-
Davis, I.D.1
Skrumsager, B.K.2
Cebon, J.3
Nicholaou, T.4
Barlow, J.W.5
Moller, N.P.6
Skak, K.7
-
88
-
-
60249091474
-
Use of tumour-responsive T cells as cancer treatment
-
Disis, M. L., Bernhard, H. and Jaffee, E. M., Use of tumour-responsive T cells as cancer treatment. Lancet 2009. 373: 673-683.
-
(2009)
Lancet
, vol.373
, pp. 673-683
-
-
Disis, M.L.1
Bernhard, H.2
Jaffee, E.M.3
-
89
-
-
51349123892
-
Cancer immunotherapy by dendritic cells
-
Melief, C. J., Cancer immunotherapy by dendritic cells. Immunity 2008. 29: 372-383.
-
(2008)
Immunity
, vol.29
, pp. 372-383
-
-
Melief, C.J.1
-
90
-
-
67349223911
-
Dendritic-cell- And peptide-based vaccination strategies for glioma
-
discussion 273
-
Yamanaka, R., Dendritic-cell- and peptide-based vaccination strategies for glioma. Neurosurg. Rev. 2009. 32: 265-273; discussion 273.
-
(2009)
Neurosurg. Rev.
, vol.32
, pp. 265-273
-
-
Yamanaka, R.1
-
91
-
-
70350504578
-
Targets of protective tumor immunity
-
Dranoff, G., Targets of protective tumor immunity. Ann. NY Acad. Sci. 2009. 1174: 74-80.
-
(2009)
Ann. NY Acad. Sci.
, vol.1174
, pp. 74-80
-
-
Dranoff, G.1
-
92
-
-
46049110918
-
Sipuleucel-T for the treatment of prostate cancer
-
Harzstark, A. L. and Small, E. J., Sipuleucel-T for the treatment of prostate cancer. Drugs Today (Barc) 2008. 44: 271-278.
-
(2008)
Drugs Today (Barc)
, vol.44
, pp. 271-278
-
-
Harzstark, A.L.1
Small, E.J.2
-
93
-
-
45549099784
-
Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1
-
Hunder, N. N., Wallen, H., Cao, J., Hendricks, D. W., Reilly, J. Z., Rodmyre, R., Jungbluth, A. et al., Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1. N. Engl. J. Med .2008. 358: 2698-2703.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 2698-2703
-
-
Hunder, N.N.1
Wallen, H.2
Cao, J.3
Hendricks, D.W.4
Reilly, J.Z.5
Rodmyre, R.6
Jungbluth, A.7
-
94
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
Morgan, R. A., Dudley, M. E.,Wunderlich, J. R., Hughes, M. S., Yang, J. C., Sherry, R. M., Royal, R. E. et al., Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 2006. 314: 126-129.
-
(2006)
Science
, vol.314
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
Hughes, M.S.4
Yang, J.C.5
Sherry, R.M.6
Royal, R.E.7
-
95
-
-
70449516435
-
The allogeneic graft-versus-cancer effect
-
Ringden, O., Karlsson, H., Olsson, R., Omazic, B. and Uhlin, M., The allogeneic graft-versus-cancer effect. Br. J. Haematol. 2009. 147: 614-633.
-
(2009)
Br. J. Haematol.
, vol.147
, pp. 614-633
-
-
Ringden, O.1
Karlsson, H.2
Olsson, R.3
Omazic, B.4
Uhlin, M.5
-
96
-
-
0037086131
-
Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
-
Ruggeri, L., Capanni, M., Urbani, E., Perruccio, K., Shlomchik, W. D., Tosti, A., Posati, S. et al., Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 2002. 295: 2097-2100.
-
(2002)
Science
, vol.295
, pp. 2097-2100
-
-
Ruggeri, L.1
Capanni, M.2
Urbani, E.3
Perruccio, K.4
Shlomchik, W.D.5
Tosti, A.6
Posati, S.7
-
97
-
-
20144388509
-
Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer
-
Miller, J. S., Soignier, Y., Panoskaltsis-Mortari, A., McNearney, S. A., Yun, G. H., Fautsch, S. K., McKenna, D. et al., Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. Blood 2005. 105: 3051-3057.
-
(2005)
Blood
, vol.105
, pp. 3051-3057
-
-
Miller, J.S.1
Soignier, Y.2
Panoskaltsis-Mortari, A.3
McNearney, S.A.4
Yun, G.H.5
Fautsch, S.K.6
McKenna, D.7
-
98
-
-
17144363277
-
Use of natural killer cells in hematopoetic stem cell transplantation
-
DOI 10.1038/sj.bmt.1704810
-
Passweg, J. R., Stern, M., Koehl, U., Uharek, L. and Tichelli, A., Use of natural killer cells in hematopoetic stem cell transplantation. Bone Marrow Transplant. 2005. 35: 637-643. (Pubitemid 40520947)
-
(2005)
Bone Marrow Transplantation
, vol.35
, Issue.7
, pp. 637-643
-
-
Passweg, J.R.1
Stern, M.2
Koehl, U.3
Uharek, L.4
Tichelli, A.5
-
99
-
-
67650467728
-
Modulating T-cell homeostasis with IL-7: Preclinical and clinical studies
-
Capitini, C. M., Chisti, A. A. and Mackall, C. L., Modulating T-cell homeostasis with IL-7: preclinical and clinical studies. J. Intern. Med. 2009. 266: 141-153.
-
(2009)
J. Intern. Med.
, vol.266
, pp. 141-153
-
-
Capitini, C.M.1
Chisti, A.A.2
Mackall, C.L.3
-
100
-
-
33750121077
-
A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127
-
Vosshenrich,C. A., Garcia-Ojeda, M. E., Samson-Villeger, S. I., Pasqualetto, V., Enault, L., Richard-Le Goff, O., Corcuff, E. et al., A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127. Nat. Immunol. 2006. 7: 1217-1224.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1217-1224
-
-
Vosshenrich, C.A.1
Garcia-Ojeda, M.E.2
Samson-Villeger, S.I.3
Pasqualetto, V.4
Enault, L.5
Richard-Le Goff, O.6
Corcuff, E.7
-
101
-
-
77149155687
-
IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors
-
Satoh-Takayama, N., Lesjean-Pottier, S., Vieira, P., Sawa, S., Eberl, G., Vosshenrich, C. A. and Di Santo, J. P., IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors. J. Exp. Med. 2010. 207: 273-280.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 273-280
-
-
Satoh-Takayama, N.1
Lesjean-Pottier, S.2
Vieira, P.3
Sawa, S.4
Eberl, G.5
Vosshenrich, C.A.6
Di Santo, J.P.7
-
102
-
-
70149094177
-
Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells
-
Schmutz, S., Bosco, N., Chappaz, S., Boyman, O., Acha-Orbea, H., Ceredig, R., Rolink, A. G. and Finke, D., Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells. J. Immunol. 2009. 183: 2217-2221.
-
(2009)
J. Immunol.
, vol.183
, pp. 2217-2221
-
-
Schmutz, S.1
Bosco, N.2
Chappaz, S.3
Boyman, O.4
Acha-Orbea, H.5
Ceredig, R.6
Rolink, A.G.7
Finke, D.8
-
103
-
-
34248573325
-
Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue-inducer cells
-
Meier, D., Bornmann, C., Chappaz, S., Schmutz, S., Otten, L. A., Ceredig, R., Acha-Orbea, H. and Finke, D., Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue-inducer cells. Immunity 2007. 26: 643-654.
-
(2007)
Immunity
, vol.26
, pp. 643-654
-
-
Meier, D.1
Bornmann, C.2
Chappaz, S.3
Schmutz, S.4
Otten, L.A.5
Ceredig, R.6
Acha-Orbea, H.7
Finke, D.8
-
104
-
-
65449185003
-
Novel function for interleukin-7 in dendritic cell development
-
Vogt, T. K., Link, A., Perrin, J., Finke, D. and Luther, S. A., Novel function for interleukin-7 in dendritic cell development. Blood 2009. 113: 3961-3968.
-
(2009)
Blood
, vol.113
, pp. 3961-3968
-
-
Vogt, T.K.1
Link, A.2
Perrin, J.3
Finke, D.4
Luther, S.A.5
-
105
-
-
0035469821
-
Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27kip1
-
Barata, J. T., Cardoso, A. A., Nadler, L. M. and Boussiotis, V. A., Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27kip1. Blood 2001. 98: 1524-1531.
-
(2001)
Blood
, vol.98
, pp. 1524-1531
-
-
Barata, J.T.1
Cardoso, A.A.2
Nadler, L.M.3
Boussiotis, V.A.4
-
106
-
-
0028114542
-
Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor
-
Boussiotis, V. A., Barber, D. L., Nakarai, T., Freeman, G. J., Gribben, J. G., Bernstein, G. M., D'Andrea, A. D. et al., Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor. Science 1994. 266: 1039-1042.
-
(1994)
Science
, vol.266
, pp. 1039-1042
-
-
Boussiotis, V.A.1
Barber, D.L.2
Nakarai, T.3
Freeman, G.J.4
Gribben, J.G.5
Bernstein, G.M.6
D'Andrea, A.D.7
-
107
-
-
0033621780
-
p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes
-
Boussiotis, V. A., Freeman, G. J., Taylor, P. A., Berezovskaya, A., Grass, I., Blazar, B. R. and Nadler, L. M., p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes. Nat. Med. 2000. 6: 290-297.
-
(2000)
Nat. Med.
, vol.6
, pp. 290-297
-
-
Boussiotis, V.A.1
Freeman, G.J.2
Taylor, P.A.3
Berezovskaya, A.4
Grass, I.5
Blazar, B.R.6
Nadler, L.M.7
-
108
-
-
33847072648
-
Induction of granzyme B and T cell cytotoxic capacity by IL-2 or IL-15 without antigens: Multiclonal responses that are extremely lytic if triggered and short-lived after cytokine withdrawal
-
Tamang, D. L., Redelman, D., Alves, B. N., Vollger, L., Bethley, C. and Hudig, D., Induction of granzyme B and T cell cytotoxic capacity by IL-2 or IL-15 without antigens: multiclonal responses that are extremely lytic if triggered and short-lived after cytokine withdrawal. Cytokine 2006. 36: 148-159.
-
(2006)
Cytokine
, vol.36
, pp. 148-159
-
-
Tamang, D.L.1
Redelman, D.2
Alves, B.N.3
Vollger, L.4
Bethley, C.5
Hudig, D.6
-
109
-
-
68049106295
-
Homeostatic (IL-7) and effector (IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease
-
Kanai, T., Nemoto, Y., Kamada, N., Totsuka, T., Hisamatsu, T., Watanabe, M. and Hibi, T., Homeostatic (IL-7) and effector (IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease. Curr. Opin. Gastroenterol. 2009. 25: 306-313.
-
(2009)
Curr. Opin. Gastroenterol.
, vol.25
, pp. 306-313
-
-
Kanai, T.1
Nemoto, Y.2
Kamada, N.3
Totsuka, T.4
Hisamatsu, T.5
Watanabe, M.6
Hibi, T.7
-
110
-
-
49649119363
-
NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways
-
Verhoeven, D. H., de Hooge, A. S., Mooiman, E. C., Santos, S. J., ten Dam, M. M., Gelderblom, H., Melief, C. J. et al., NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways. Mol. Immunol. 2008. 45: 3917-3925.
-
(2008)
Mol. Immunol.
, vol.45
, pp. 3917-3925
-
-
Verhoeven, D.H.1
De Hooge, A.S.2
Mooiman, E.C.3
Santos, S.J.4
Ten Dam, M.M.5
Gelderblom, H.6
Melief, C.J.7
-
111
-
-
65449177238
-
NK cells recognize and kill human glioblastoma cells with stem cell-like properties
-
Castriconi, R., Daga, A., Dondero, A., Zona, G., Poliani, P. L., Melotti, A., Griffero, F. et al., NK cells recognize and kill human glioblastoma cells with stem cell-like properties. J. Immunol. 2009. 182: 3530-3539.
-
(2009)
J. Immunol.
, vol.182
, pp. 3530-3539
-
-
Castriconi, R.1
Daga, A.2
Dondero, A.3
Zona, G.4
Poliani, P.L.5
Melotti, A.6
Griffero, F.7
-
112
-
-
36049007739
-
NK cell survival mediated through the regulatory synapse with human DCs requires IL-15Ralpha
-
Brilot, F., Strowig, T., Roberts, S. M., Arrey, F. and Munz, C., NK cell survival mediated through the regulatory synapse with human DCs requires IL-15Ralpha. J. Clin. Invest. 2007. 117: 3316-3329.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 3316-3329
-
-
Brilot, F.1
Strowig, T.2
Roberts, S.M.3
Arrey, F.4
Munz, C.5
-
113
-
-
34247100277
-
Dendritic cells prime natural killer cells by trans-presenting interleukin 15
-
Lucas, M., Schachterle, W., Oberle, K., Aichele, P. and Diefenbach, A., Dendritic cells prime natural killer cells by trans-presenting interleukin 15. Immunity 2007. 26: 503-517.
-
(2007)
Immunity
, vol.26
, pp. 503-517
-
-
Lucas, M.1
Schachterle, W.2
Oberle, K.3
Aichele, P.4
Diefenbach, A.5
-
114
-
-
33746046073
-
IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells
-
Rosenberg, S. A., Sportes, C., Ahmadzadeh, M., Fry, T. J., Ngo, L. T., Schwarz, S. L., Stetler-Stevenson, M. et al., IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells. J. Immunother. 2006. 29: 313-319.
-
(2006)
J. Immunother.
, vol.29
, pp. 313-319
-
-
Rosenberg, S.A.1
Sportes, C.2
Ahmadzadeh, M.3
Fry, T.J.4
Ngo, L.T.5
Schwarz, S.L.6
Stetler-Stevenson, M.7
-
115
-
-
0031749740
-
Vaccination with IL-7 gene-modified autologous melanoma cells can enhance the anti-melanoma lytic activity in peripheral blood of patients with a good clinical performance status: A clinical phase I study
-
Moller, P., Sun, Y., Dorbic, T., Alijagic, S., Makki, A., Jurgovsky, K., Schroff, M. et al., Vaccination with IL-7 gene-modified autologous melanoma cells can enhance the anti-melanoma lytic activity in peripheral blood of patients with a good clinical performance status: a clinical phase I study. Br. J. Cancer 1998. 77: 1907-1916.
-
(1998)
Br. J. Cancer
, vol.77
, pp. 1907-1916
-
-
Moller, P.1
Sun, Y.2
Dorbic, T.3
Alijagic, S.4
Makki, A.5
Jurgovsky, K.6
Schroff, M.7
-
116
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
Hafler, D. A., Compston, A., Sawcer, S., Lander, E. S., Daly, M. J., De Jager, P. L., de Bakker, P. I. et al. Risk alleles for multiple sclerosis identified by a genomewide study. N. Engl. J. Med. 2007. 357: 851-862.
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 851-862
-
-
Hafler, D.A.1
Compston, A.2
Sawcer, S.3
Lander, E.S.4
Daly, M.J.5
De Jager, P.L.6
De Bakker, P.I.7
-
117
-
-
34548368541
-
Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis
-
Lundmark, F., Duvefelt, K., Iacobaeus, E., Kockum, I., Wallstrom, E., Khademi, M., Oturai, A. et al., Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. Nat. Genet. 2007. 39: 1108-1113.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1108-1113
-
-
Lundmark, F.1
Duvefelt, K.2
Iacobaeus, E.3
Kockum, I.4
Wallstrom, E.5
Khademi, M.6
Oturai, A.7
-
118
-
-
0041808918
-
Identification of 11 novel and common single nucleotide polymorphisms in the interleukin-7 receptor-alpha gene and their associations with multiple sclerosis
-
Teutsch, S. M., Booth, D. R., Bennetts, B. H., Heard, R. N. and Stewart, G. J., Identification of 11 novel and common single nucleotide polymorphisms in the interleukin-7 receptor-alpha gene and their associations with multiple sclerosis. Eur. J. Hum. Genet. 2003. 11: 509-515.
-
(2003)
Eur. J. Hum. Genet.
, vol.11
, pp. 509-515
-
-
Teutsch, S.M.1
Booth, D.R.2
Bennetts, B.H.3
Heard, R.N.4
Stewart, G.J.5
|