Homeostatic (IL-7) and effector (IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease

Current Opinion in Gastroenterology

Volumn 25, Issue 4, 2009, Pages 306-313

  Kanai, Takanori ^a   Nemoto, Yasuhiro ^b   Kamada, Nobuhiko ^a   Totsuka, Teruji ^b   Hisamatsu, Tadakazu ^a   Watanabe, Mamoru ^b   Hibi, Toshifumi ^a  

^a KEIO UNIVERSITY   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Colitogenic memory CD4+ T cells; IL 7; Inflammatory bowel disease; Regulatory T cells; Th17

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; INTERLEUKIN 7; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL POPULATION; CROHN DISEASE; DISEASE CLASSIFICATION; DISEASE COURSE; EFFECTOR CELL; ENTERITIS; GENE EXPRESSION; HOMEOSTASIS; MEMORY T LYMPHOCYTE; NATURAL KILLER CELL; NONHUMAN; PATHOGENESIS; REGULATORY T LYMPHOCYTE; RELAPSE; REVIEW; SCID MOUSE; TARGET CELL; TH1 CELL; TH2 CELL; ULCERATIVE COLITIS;

ANIMALS; COHORT STUDIES; CYTOKINES; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; HOMEOSTASIS; IMMUNOLOGIC MEMORY; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-17; INTERLEUKIN-7; MICE; MICE, INBRED BALB C; MICE, SCID; SENSITIVITY AND SPECIFICITY; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY;

EID: 68049106295     PISSN: 02671379     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOG.0b013e32832bc627     Document Type: Review

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