-
1
-
-
0034597789
-
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
-
Parrish-Novak J, Dillon SR, Nelson A et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 2000 408 : 57 63.
-
(2000)
Nature
, vol.408
, pp. 57-63
-
-
Parrish-Novak, J.1
Dillon, S.R.2
Nelson, A.3
-
2
-
-
33847367120
-
IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production
-
Coquet JM, Kyparissoudis K, Pellicci DG, Besra G, Berzins SP, Smyth MJ, Godfrey DI. IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production. J Immunol 2007 178 : 2827 34.
-
(2007)
J Immunol
, vol.178
, pp. 2827-34
-
-
Coquet, J.M.1
Kyparissoudis, K.2
Pellicci, D.G.3
Besra, G.4
Berzins, S.P.5
Smyth, M.J.6
Godfrey, D.I.7
-
3
-
-
2942709751
-
Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis
-
Jin H, Carrio R, Yu A, Malek TR. Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis. J Immunol 2004 173 : 657 65.
-
(2004)
J Immunol
, vol.173
, pp. 657-65
-
-
Jin, H.1
Carrio, R.2
Yu, A.3
Malek, T.R.4
-
4
-
-
25444434157
-
Interleukin-21: A modulator of lymphoid proliferation, apoptosis and differentiation
-
Leonard WJ, Spolski R. Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation. Nat Rev Immunol 2005 5 : 688 98.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 688-98
-
-
Leonard, W.J.1
Spolski, R.2
-
5
-
-
0842278642
-
IL-21 induces the functional maturation of murine NK cells
-
Brady J, Hayakawa Y, Smyth MJ, Nutt SL. IL-21 induces the functional maturation of murine NK cells. J Immunol 2004 172 : 2048 58.
-
(2004)
J Immunol
, vol.172
, pp. 2048-58
-
-
Brady, J.1
Hayakawa, Y.2
Smyth, M.J.3
Nutt, S.L.4
-
6
-
-
18344394955
-
IL-21 limits NK cell responses and promotes antigen-specific T cell activation: A mediator of the transition from innate to adaptive immunity
-
Kasaian MT, Whitters MJ, Carter LL et al. IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity. Immunity 2002 16 : 559 69.
-
(2002)
Immunity
, vol.16
, pp. 559-69
-
-
Kasaian, M.T.1
Whitters, M.J.2
Carter, L.L.3
-
7
-
-
0348013081
-
IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors
-
Sivori S, Cantoni C, Parolini S, Marcenaro E, Conte R, Moretta L, Moretta A. IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors. Eur J Immunol 2003 33 : 3439 47.
-
(2003)
Eur J Immunol
, vol.33
, pp. 3439-47
-
-
Sivori, S.1
Cantoni, C.2
Parolini, S.3
Marcenaro, E.4
Conte, R.5
Moretta, L.6
Moretta, A.7
-
8
-
-
34347387967
-
Interleukin 21 therapy increases the density of tumor infiltrating CD8+ T cells and inhibits the growth of syngeneic tumors
-
Søndergaard H, Frederiksen KS, Thygesen P, Galsgaard ED, Skak K, Kristjansen PEG, Ødum N, Kragh M. Interleukin 21 therapy increases the density of tumor infiltrating CD8+ T cells and inhibits the growth of syngeneic tumors. Cancer Immunol Immunother 2007 56 : 1417 28.
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 1417-28
-
-
Søndergaard, H.1
Frederiksen, K.S.2
Thygesen, P.3
Galsgaard, E.D.4
Skak, K.5
Kristjansen, P.E.G.6
Ødum, N.7
Kragh, M.8
-
9
-
-
1642444178
-
IL-21 induces tumor rejection by specific CTL and IFN-gamma-dependent CXC chemokines in syngeneic mice
-
Di Carlo E, Comes A, Orengo AM, Rosso O, Meazza R, Musiani P, Colombo MP, Ferrini S. IL-21 induces tumor rejection by specific CTL and IFN-gamma-dependent CXC chemokines in syngeneic mice. J Immunol 2004 172 : 1540 7.
-
(2004)
J Immunol
, vol.172
, pp. 1540-7
-
-
Di Carlo, E.1
Comes, A.2
Orengo, A.M.3
Rosso, O.4
Meazza, R.5
Musiani, P.6
Colombo, M.P.7
Ferrini, S.8
-
10
-
-
10744230081
-
Interleukin (IL)-21 and IL-15 genetic transfer synergistically augments therapeutic antitumor immunity and promotes regression of metastatic lymphoma
-
Kishida T, Asada H, Itokawa Y et al. Interleukin (IL)-21 and IL-15 genetic transfer synergistically augments therapeutic antitumor immunity and promotes regression of metastatic lymphoma. Mol Ther 2003 8 : 552 8.
-
(2003)
Mol Ther
, vol.8
, pp. 552-8
-
-
Kishida, T.1
Asada, H.2
Itokawa, Y.3
-
11
-
-
2542595794
-
+ T cell responses to achieve durable tumor immunity: Comparative evaluation of IL-2, IL-15, and IL-21
-
+ T cell responses to achieve durable tumor immunity: comparative evaluation of IL-2, IL-15, and IL-21. J Immunol 2004 173 : 900 9.
-
(2004)
J Immunol
, vol.173
, pp. 900-9
-
-
Moroz, A.1
Eppolito, C.2
Li, Q.3
Tao, J.4
Clegg, C.H.5
Shrikant, P.A.6
-
12
-
-
0347320749
-
In vivo antitumor activity of interleukin 21 mediated by natural killer cells
-
Wang G, Tschoi M, Spolski R et al. In vivo antitumor activity of interleukin 21 mediated by natural killer cells. Cancer Res 2003 63 : 9016 22.
-
(2003)
Cancer Res
, vol.63
, pp. 9016-22
-
-
Wang, G.1
Tschoi, M.2
Spolski, R.3
-
13
-
-
34250761481
-
An open-label, two-arm, phase I trial of recombinant human interleukin-21 in patients with metastatic melanoma
-
Davis ID, Skrumsager BK, Cebon J et al. An open-label, two-arm, phase I trial of recombinant human interleukin-21 in patients with metastatic melanoma. Clin Cancer Res 2007 13 : 3630 6.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3630-6
-
-
Davis, I.D.1
Skrumsager, B.K.2
Cebon, J.3
-
14
-
-
31144479124
-
IL-21 down-regulates NKG2D/DAP10 expression on human NK and CD8+ T cells
-
Burgess SJ, Marusina AI, Pathmanathan I, Borrego F, Coligan JE. IL-21 down-regulates NKG2D/DAP10 expression on human NK and CD8+ T cells. J Immunol 2006 176 : 1490 7.
-
(2006)
J Immunol
, vol.176
, pp. 1490-7
-
-
Burgess, S.J.1
Marusina, A.I.2
Pathmanathan, I.3
Borrego, F.4
Coligan, J.E.5
-
15
-
-
23444453820
-
2B4/CD48-mediated regulation of lymphocyte activation and function
-
Assarsson E, Kambayashi T, Persson CM, Chambers BJ, Ljunggren HG. 2B4/CD48-mediated regulation of lymphocyte activation and function. J Immunol 2005 175 : 2045 9.
-
(2005)
J Immunol
, vol.175
, pp. 2045-9
-
-
Assarsson, E.1
Kambayashi, T.2
Persson, C.M.3
Chambers, B.J.4
Ljunggren, H.G.5
-
16
-
-
2942707968
-
NK cells stimulate proliferation of T and NK cells through 2B4/CD48 interactions
-
Assarsson E, Kambayashi T, Schatzle JD, Cramer SO, von Bonin A, Jensen PE, Ljunggren HG, Chambers BJ. NK cells stimulate proliferation of T and NK cells through 2B4/CD48 interactions. J Immunol 2004 173 : 174 80.
-
(2004)
J Immunol
, vol.173
, pp. 174-80
-
-
Assarsson, E.1
Kambayashi, T.2
Schatzle, J.D.3
Cramer, S.O.4
Von Bonin, A.5
Jensen, P.E.6
Ljunggren, H.G.7
Chambers, B.J.8
-
17
-
-
30344457351
-
Effect of IL-21 on NK cells derived from different umbilical cord blood populations
-
Perez SA, Mahaira LG, Sotiropoulou PA et al. Effect of IL-21 on NK cells derived from different umbilical cord blood populations. Int Immunol 2006 18 : 49 58.
-
(2006)
Int Immunol
, vol.18
, pp. 49-58
-
-
Perez, S.A.1
Mahaira, L.G.2
Sotiropoulou, P.A.3
-
18
-
-
0032945045
-
NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells
-
Sivori S, Pende D, Bottino C, Marcenaro E, Pessino A, Biassoni R, Moretta L, Moretta A. NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells. Eur J Immunol 1999 29 : 1656 66.
-
(1999)
Eur J Immunol
, vol.29
, pp. 1656-66
-
-
Sivori, S.1
Pende, D.2
Bottino, C.3
Marcenaro, E.4
Pessino, A.5
Biassoni, R.6
Moretta, L.7
Moretta, A.8
-
19
-
-
1842763735
-
Killer cell immunoglobulin-like receptor diversity: Balancing signals in the natural killer cell response
-
Parham P. Killer cell immunoglobulin-like receptor diversity: balancing signals in the natural killer cell response. Immunol Lett 2004 92 : 11 3.
-
(2004)
Immunol Lett
, vol.92
, pp. 11-3
-
-
Parham, P.1
-
20
-
-
22344451592
-
Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer
-
Smyth MJ, Wallace ME, Nutt SL, Yagita H, Godfrey DI, Hayakawa Y. Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer. J Exp Med 2005 201 : 1973 85.
-
(2005)
J Exp Med
, vol.201
, pp. 1973-85
-
-
Smyth, M.J.1
Wallace, M.E.2
Nutt, S.L.3
Yagita, H.4
Godfrey, D.I.5
Hayakawa, Y.6
-
21
-
-
23444459564
-
IL-21 enhances tumor rejection through a NKG2D-dependent mechanism
-
Takaki R, Hayakawa Y, Nelson A, Sivakumar PV, Hughes S, Smyth MJ, Lanier LL. IL-21 enhances tumor rejection through a NKG2D-dependent mechanism. J Immunol 2005 175 : 2167 73.
-
(2005)
J Immunol
, vol.175
, pp. 2167-73
-
-
Takaki, R.1
Hayakawa, Y.2
Nelson, A.3
Sivakumar, P.V.4
Hughes, S.5
Smyth, M.J.6
Lanier, L.L.7
-
22
-
-
31144449386
-
CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity
-
Hayakawa Y, Smyth MJ. CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity. J Immunol 2006 176 : 1517 24.
-
(2006)
J Immunol
, vol.176
, pp. 1517-24
-
-
Hayakawa, Y.1
Smyth, M.J.2
-
23
-
-
23844501960
-
Multiple cytokines regulate the NK gene complex-encoded receptor repertoire of mature NK cells and T cells
-
Gays F, Martin K, Kenefeck R, Aust JG, Brooks CG. Multiple cytokines regulate the NK gene complex-encoded receptor repertoire of mature NK cells and T cells. J Immunol 2005 175 : 2938 47.
-
(2005)
J Immunol
, vol.175
, pp. 2938-47
-
-
Gays, F.1
Martin, K.2
Kenefeck, R.3
Aust, J.G.4
Brooks, C.G.5
-
24
-
-
0034924584
-
Factors regulating the cytotoxic activity of the human natural killer cell line, NK-92
-
Maki G, Klingemann HG, Martinson JA, Tam YK. Factors regulating the cytotoxic activity of the human natural killer cell line, NK-92. J Hematother Stem Cell Res 2001 10 : 369 83.
-
(2001)
J Hematother Stem Cell Res
, vol.10
, pp. 369-83
-
-
Maki, G.1
Klingemann, H.G.2
Martinson, J.A.3
Tam, Y.K.4
-
25
-
-
9144233578
-
Novel insights on human NK cells' immunological modalities revealed by gene expression profiling
-
Hanna J, Bechtel P, Zhai Y, Youssef F, McLachlan K, Mandelboim O. Novel insights on human NK cells' immunological modalities revealed by gene expression profiling. J Immunol 2004 173 : 6547 63.
-
(2004)
J Immunol
, vol.173
, pp. 6547-63
-
-
Hanna, J.1
Bechtel, P.2
Zhai, Y.3
Youssef, F.4
McLachlan, K.5
Mandelboim, O.6
-
26
-
-
32244445715
-
A novel dendritic cell subset involved in tumor immunosurveillance
-
Taieb J, Chaput N, Monard C et al. A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med 2006 12 : 214 9.
-
(2006)
Nat Med
, vol.12
, pp. 214-9
-
-
Taieb, J.1
Chaput, N.2
Monard, C.3
-
27
-
-
32244448339
-
Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity
-
Chan CW, Crafton E, Fan HN et al. Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity. Nat Med 2006 12 : 207 13.
-
(2006)
Nat Med
, vol.12
, pp. 207-13
-
-
Chan, C.W.1
Crafton, E.2
Fan, H.N.3
-
28
-
-
33748298768
-
What is natural in natural killer cells?
-
Vivier E. What is natural in natural killer cells? Immunol Lett 2006 107 : 1 7.
-
(2006)
Immunol Lett
, vol.107
, pp. 1-7
-
-
Vivier, E.1
-
29
-
-
0036779576
-
Functional significance of the perforin/granzyme cell death pathway
-
Trapani JA, Smyth MJ. Functional significance of the perforin/granzyme cell death pathway. Nat Rev Immunol 2002 2 : 735 47.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 735-47
-
-
Trapani, J.A.1
Smyth, M.J.2
-
30
-
-
33646489777
-
IL-21 enhances tumor-specific CTL induction by anti-DR5 antibody therapy
-
Smyth MJ, Hayakawa Y, Cretney E, Zerafa N, Sivakumar P, Yagita H, Takeda K. IL-21 enhances tumor-specific CTL induction by anti-DR5 antibody therapy. J Immunol 2006 176 : 6347 55.
-
(2006)
J Immunol
, vol.176
, pp. 6347-55
-
-
Smyth, M.J.1
Hayakawa, Y.2
Cretney, E.3
Zerafa, N.4
Sivakumar, P.5
Yagita, H.6
Takeda, K.7
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