A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127

Nature Immunology

Volumn 7, Issue 11, 2006, Pages 1217-1224

  Vosshenrich, Christian A J ^a   García Ojeda, Marcos E ^a   Samson Villéger, Sandrine I ^a   Pasqualetto, Valerie ^b   Enault, Laurence ^a   Goff, Odile Richard Le ^a   Corcuff, Erwan ^a   Guy Grand, Delphine ^a   Rocha, Benedita ^b   Cumano, Ana ^a   Rogge, Lars ^c   Ezine, Sophie ^b   Di Santo, James P ^a  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD16 ANTIGEN; CD56 ANTIGEN; CD69 ANTIGEN; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; TRANSCRIPTION FACTOR GATA 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HOMEOSTASIS; HUMAN; HUMAN CELL; LYMPHOCYTE SUBPOPULATION; MOUSE; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; THYMUS;

ANIMALS; CELL DIFFERENTIATION; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; GATA3 TRANSCRIPTION FACTOR; HUMANS; IMMUNOPHENOTYPING; INTERLEUKIN-7; INTERLEUKIN-7 RECEPTOR ALPHA SUBUNIT; KILLER CELLS, NATURAL; LYMPHOCYTE SUBSETS; MICE; MICE, INBRED C57BL; MICE, NUDE; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; THYMUS GLAND;

EID: 33750121077     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1395     Document Type: Article

References (42)

1. Herberman, R.B., Nunn, M.E., Holden, H.T. & Lavrin, D.H. Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cells. Int. J. Cancer 16, 230-239 (1975).
2. Di Santo, J.P. Natural killer cell developmental pathways: A question of balance. Annu. Rev. Immunol. 24, 257-286 (2006).
3. Vosshenrich, C.A., Samson Villeger, S.I. & Di Santo, J.P. Distinguishing features of developing natural killer cells. Curr. Opin. Immunol. 17, 151-158 (2005).
4. Rosmaraki, E.E. et al. Identification of committed NK cell progenitors in adult murine bone marrow. Eur. J. Immunol. 31, 1900-1909 (2001).
5. Raulet, D.H., Vance, R.E. & McMahon, C.W. Regulation of the natural killer cell receptor repertoire. Annu. Rev. Immunol. 19, 291-330 (2001).
6. Kim, S. et al. In vivo developmental stages in murine natural killer cell maturation. Nat. Immunol. 3, 523-528 (2002).
7. Cooper, M.A. et al. In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells. Blood 100, 3633-3638 (2002).
8. Kennedy, M.K. et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J. Exp. Med. 191, 771-780 (2000).
9. + hematopoietic progenitor cells. Blood 87, 2632-2640 (1996).
10. Ranson, T. et al. IL-15 is an essential mediator of peripheral NK cell homeostasis. Blood (2003).
11. Peschon, J.J. et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J. Exp. Med. 180, 1955-1960 (1994).
12. + T cells, but not natural killer cells. J. Exp. Med. 184, 289-293 (1996).
13. -/- mice. J. Immunol. 157, 2366-2373 (1996).
14. Vosshenrich, C.A. et al. Roles for common cytokine receptor γ-chain-dependent cytokines in the generation, differentiation, and maturation of NK cell precursors and peripheral NK cells in vivo. J. Immunol. 174, 1213-1221 (2005).
15. Rothenberg, E.V. & Taghon, T. Molecular genetics of T cell development. Annu. Rev. Immunol. 23, 601-649 (2005).
16. Singh, H., Medina, K.L. & Pongubala, J.M. Contingent gene regulatory networks and B cell fate specification. Proc. Natl. Acad. Sci. USA 102, 4949-4953 (2005).
17. Samson, S.I. et al. GATA3 promotes maturation, IFN-γ production, and liver-specific homing of NK cells. Immunity 19, 701-711 (2003).
18. Taki, S., Nakajima, S., Ichikawa, E., Saito, T. & Hida, S. IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells. J. Immunol. 174, 6005-6012 (2005).
19. α14i NKT cells. Immunity 20, 477-494 (2004).
20. Garni-Wagner, B.A. et al. Natural killer cells in the thymus. Studies in mice with severe combined immune deficiency. J. Immunol. 144, 796-803 (1990).
21. Takeda, K. et al. TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver. Blood 105, 2082-2089 (2005).
22. Haller, O. & Wigzell, H. Suppression of natural killer cell activity with radioactive strontium: Effector cells are marrow dependent. J. Immunol. 118, 1503-1506 (1977).
23. Puzanov, I.J., Bennett, M. & Kumar, V. IL-15 can substitute for the marrow micro-environment in the differentiation of natural killer cells. J. Immunol. 157, 4282-4285 (1996).
24. Sanchez, M.J., Muench, M.O., Roncarolo, M.G., Lanier, L.L. & Phillips, J.H. Identification of a common T/natural killer cell progenitor in human fetal thymus. J. Exp. Med. 180, 569-576 (1994).
25. Spits, H. et al. Early stages in the development of human T, natural killer and thymic dendritic cells. Immunol. Rev. 165, 75-86 (1998).
26. Michie, A.M. et al. Clonal characterization of a bipotent T cell and NK cell progenitor in the mouse fetal thymus. J. Immunol. 164, 1730-1733 (2000).
27. bright subset. Blood 97, 3146-3151 (2001).
28. Hendriks, R.W. et al. Expression of the transcription factor GATA3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus. Eur. J. Immunol. 29, 1912-1918 (1999).
29. Dong, C. & Flavell, R.A. Control of T helper cell differentiation-in search of master genes. Sci. STKE 2000 PE1 (2000).
30. Penix, L., Weaver, W.M., Pang, Y., Young, H.A. & Wilson, C.B. Two essential regulatory elements in the human interferon γ promoter confer activation specific expression in T cells. J. Exp. Med. 178, 1483-1496 (1993).
31. Leiden, J.M. Transcriptional regulation of T cell receptor genes. Annu. Rev. Immunol. 11, 539-570 (1993).
32. Ma, A., Koka, R. & Burkett, P. Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis. Annu. Rev. Immunol. 24, 657-679 (2006).
33. Degli-Esposti, M.A. & Smyth, M.J. Close encounters of different kinds: dendritic cells and NK cells take centre stage. Nat. Rev. Immunol. 5, 112-124 (2005).
34. Chan, C.W. et al. Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity. Nat. Med. 12, 207-213 (2006).
35. Taieb, J. et al. A novel dendritic cell subset involved in tumor immunosurveillance. Nat. Med. 12, 214-219 (2006).
36. H1 priming. Nat. Immunol. 5, 1260-1265 (2004).
37. Ferlazzo, G. & Munz, C. NK cell compartments and their activation by dendritic cells. J. Immunol. 172, 1333-1339 (2004).
38. bright natural killer cells. Immunity 22, 295-304 (2005).
39. Hansson, M., Kiessling, R., Andersson, B., Karre, K. & Roder, J. NK cell-sensitive T-cell subpopulation in thymus: Inverse correlation to host NK activity. Nature 278, 174-176 (1979).
40. Schott, E., Bonasio, R. & Ploegh, H.L. Elimination in vivo of developing T cells by natural killer cells. J. Exp. Med. 198, 1213-1224 (2003).
41. Mowen, K.A. & Glimcher, L.H. Signaling pathways in Th2 development. Immunol. Rev. 202, 203-222 (2004).
42. Haddad, R. et al. Dynamics of thymus-colonizing cells during human development. Immunity 24, 217-230 (2006).