메뉴 건너뛰기




Volumn 4, Issue 3, 2010, Pages 201-224

New biomarkers for lung cancer

Author keywords

Early detection; Genomics; Lung cancer; Metabolomics; Molecular biomarkers; Prognosis; Proteomics; Screening

Indexed keywords

AUTOANTIBODY; C REACTIVE PROTEIN; CA 125 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CYCLIN D1; CYCLINE; CYTOKERATIN 19 FRAGMENT; EPIDERMAL GROWTH FACTOR RECEPTOR; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; KI 67 ANTIGEN; MICRORNA; NEURON SPECIFIC ENOLASE; PROGASTRIN RELEASING PEPTIDE; PROTEIN MDM2; PROTEIN P14; PROTEIN P15; PROTEIN P16; PROTEIN P18; PROTEIN P19; PROTEIN P21; PROTEIN P27; PROTEIN P53; PROTEIN P57; RETINOBLASTOMA PROTEIN; RIBONUCLEOTIDE REDUCTASE; SQUAMOUS CELL CARCINOMA ANTIGEN; TISSUE POLYPEPTIDE ANTIGEN; TRANSFORMING GROWTH FACTOR BETA; TUMOR MARKER;

EID: 77953772723     PISSN: 17530059     EISSN: 17530067     Source Type: Journal    
DOI: 10.1517/17530051003725113     Document Type: Review
Times cited : (9)

References (265)
  • 1
    • 67650469082 scopus 로고    scopus 로고
    • A review of novel biological tools used in screening for the early detection of lung cancer
    • Ghosal R, Kloer P, Lewis KE. A review of novel biological tools used in screening for the early detection of lung cancer. Postgrad Med J 2009;85:358-363
    • (2009) Postgrad Med J , vol.85 , pp. 358-363
    • Ghosal, R.1    Kloer, P.2    Lewis, K.E.3
  • 3
    • 23344438114 scopus 로고    scopus 로고
    • Cochrane systematic reviews of treatments for lung cancer
    • Fong KM, Yang IA, Zimmerman PV, et al. Cochrane systematic reviews of treatments for lung cancer. Respir Med 2005;99:1071-1078
    • (2005) Respir Med , vol.99 , pp. 1071-1078
    • Fong, K.M.1    Yang, I.A.2    Zimmerman, P.V.3
  • 5
    • 20644459456 scopus 로고    scopus 로고
    • Novel strategies for the early detection and prevention of lung cancer
    • Wardwell NR, Massion P. Novel strategies for the early detection and prevention of lung cancer. Semin Oncol 2005;32:259-268
    • (2005) Semin Oncol , vol.32 , pp. 259-268
    • Wardwell, N.R.1    Massion, P.2
  • 6
    • 73349107157 scopus 로고    scopus 로고
    • Management of lung nodules detected by volume CT scanning
    • van Klaveren RJ, Oudkerk M, Prokop M, et al. Management of lung nodules detected by volume CT scanning. N Engl J Med 2009;361:2221-2229
    • (2009) N Engl J Med , vol.361 , pp. 2221-2229
    • Van Klaveren, R.J.1    Oudkerk, M.2    Prokop, M.3
  • 7
    • 33744502855 scopus 로고    scopus 로고
    • Cancer biomarkers: An invitation to the table
    • Dalton WS, Friend SH. Cancer biomarkers: an invitation to the table. Science 2006;312:1165-1168
    • (2006) Science , vol.312 , pp. 1165-1168
    • Dalton, W.S.1    Friend, S.H.2
  • 8
    • 59949099451 scopus 로고    scopus 로고
    • Biomarkers in lung cancer: From early detection to novel therapeutics and decision making
    • Scott A, Salgia R. Biomarkers in lung cancer: from early detection to novel therapeutics and decision making. Biomark Med 2008;2:577-586
    • (2008) Biomark Med , vol.2 , pp. 577-586
    • Scott, A.1    Salgia, R.2
  • 9
    • 0038299179 scopus 로고    scopus 로고
    • Charcateristics and prognosis of patients after resection of non-small cell carcinoma measuring 2 cm or less in greatest dimension
    • Okada M, Sakamoto T, Nishio W, et al. Charcateristics and prognosis of patients after resection of non-small cell carcinoma measuring 2 cm or less in greatest dimension. Cancer 2003;98:535-541
    • (2003) Cancer , vol.98 , pp. 535-541
    • Okada, M.1    Sakamoto, T.2    Nishio, W.3
  • 10
    • 68049083613 scopus 로고    scopus 로고
    • Clinical significance of carcinoembryonic antigen level for clinical stage i non-small cell lung cancer: Can preoperative carcinoembryonic antigen level predict pathological stage?
    • Kawachi R, Nakazato Y, Takei H, et al. Clinical significance of carcinoembryonic antigen level for clinical stage I non-small cell lung cancer: can preoperative carcinoembryonic antigen level predict pathological stage? Interact Cardiovasc Thorac Surg 2009;9:199-202
    • (2009) Interact Cardiovasc Thorac Surg , vol.9 , pp. 199-202
    • Kawachi, R.1    Nakazato, Y.2    Takei, H.3
  • 11
    • 51049102813 scopus 로고    scopus 로고
    • Preoperative CYFRA 21-1 and CEA as prognostic factors in patients with stage i non-small cell lung cancer: External validation of a prognostic score
    • Blankenburg F, Hatz R, Nagel D, et al. Preoperative CYFRA 21-1 and CEA as prognostic factors in patients with stage I non-small cell lung cancer: external validation of a prognostic score. Tumour Biol 2008;29:272-277
    • (2008) Tumour Biol , vol.29 , pp. 272-277
    • Blankenburg, F.1    Hatz, R.2    Nagel, D.3
  • 12
    • 67650760768 scopus 로고    scopus 로고
    • Serum carcinoembrionic antigen level in non-small-cell lung cancer patients with preoperative normal serum level
    • Tomita M, Shimizu T, Hara M, et al. Serum carcinoembrionic antigen level in non-small-cell lung cancer patients with preoperative normal serum level. Gen Thorac Cardiovasc Surg 2009;57:303-306
    • (2009) Gen Thorac Cardiovasc Surg , vol.57 , pp. 303-306
    • Tomita, M.1    Shimizu, T.2    Hara, M.3
  • 13
    • 0012277796 scopus 로고    scopus 로고
    • Pro-gastrin-releasing peptide (ProGRP), neuron specific enolase (NSE), carcinoembryonic antigen (CEA), and cytokeratin 19-fragments (CYFRA 21-1) in patients with lung cancer in comparison to other lung diseases
    • Schneider J, Philipp M, Velcovsky HG, et al. Pro-gastrin-releasing peptide (ProGRP), neuron specific enolase (NSE), carcinoembryonic antigen (CEA), and cytokeratin 19-fragments (CYFRA 21-1) in patients with lung cancer in comparison to other lung diseases. Anticancer Res 2003;23:885-893
    • (2003) Anticancer Res , vol.23 , pp. 885-893
    • Schneider, J.1    Philipp, M.2    Velcovsky, H.G.3
  • 14
    • 52649178477 scopus 로고    scopus 로고
    • CYFRA 21.1 in non-small cell lung cancer-standardisation and application during diagnosis
    • Pavićević R, Bubanović G, Franjević A, et al. CYFRA 21.1 in non-small cell lung cancer-standardisation and application during diagnosis. Coll Antropol 2008;32:485-498
    • (2008) Coll Antropol , vol.32 , pp. 485-498
    • Pavićević, R.1    Bubanović, G.2    Franjević, A.3
  • 15
    • 0043234142 scopus 로고    scopus 로고
    • Clinical equivalence of two cytokeratin markers in mon-small cell lung cancer: A study of tissue polypeptide antigen, and cytokeratin 19 fragments
    • Buccheri G, Torchio P, Ferrigno D. Clinical equivalence of two cytokeratin markers in mon-small cell lung cancer: a study of tissue polypeptide antigen, and cytokeratin 19 fragments. Chest 2003;124:622-632
    • (2003) Chest , vol.124 , pp. 622-632
    • Buccheri, G.1    Torchio, P.2    Ferrigno, D.3
  • 16
    • 77953744322 scopus 로고    scopus 로고
    • Carcinoembryonic antigen, neuron-specific enolase and cytokeratin fragment 19 (CYFRA 21-1) levels in induced sputum of lung cancer patients
    • Hillas G, Moschos C, Dimakou K, et al. Carcinoembryonic antigen, neuron-specific enolase and cytokeratin fragment 19 (CYFRA 21-1) levels in induced sputum of lung cancer patients. Scand J Clin Lab Invest 2008;8:1-6
    • (2008) Scand J Clin Lab Invest , vol.8 , pp. 1-6
    • Hillas, G.1    Moschos, C.2    Dimakou, K.3
  • 17
    • 3042598857 scopus 로고    scopus 로고
    • Clinical utility of cytokeratins as tumour markers
    • Barak V, Goike H, Panaretakis KW, et al. Clinical utility of cytokeratins as tumour markers. Clin Biochem 2004;37:529-540
    • (2004) Clin Biochem , vol.37 , pp. 529-540
    • Barak, V.1    Goike, H.2    Panaretakis, K.W.3
  • 18
    • 34249803223 scopus 로고    scopus 로고
    • Biomarkers for lung cancer: Clinical uses
    • Greenberg AK, Lee MS. Biomarkers for lung cancer: clinical uses. Curr Opin Pulm Med 2007;13:249-255
    • (2007) Curr Opin Pulm Med , vol.13 , pp. 249-255
    • Greenberg, A.K.1    Lee, M.S.2
  • 19
    • 0043162180 scopus 로고    scopus 로고
    • Neuron-specific enolase is an effective tumour marker in non-small cell lung cancer (NSCLC)
    • Ferrigno D, Buccheri G, Giordano C. Neuron-specific enolase is an effective tumour marker in non-small cell lung cancer (NSCLC). Lung Cancer 2003;41:311-320
    • (2003) Lung Cancer , vol.41 , pp. 311-320
    • Ferrigno, D.1    Buccheri, G.2    Giordano, C.3
  • 20
    • 21244486698 scopus 로고    scopus 로고
    • Pro-gastrin-releasing peptide (proGRP) in patients with benign, and malignant diseases: Comparison with CEA, SCC, CYFRA 21-1, and NSE in patients with lung cancer
    • Molina R, Auge JM, Filella X, et al. Pro-gastrin-releasing peptide (proGRP) in patients with benign, and malignant diseases: comparison with CEA, SCC, CYFRA 21-1, and NSE in patients with lung cancer. Anticancer Res 2005;25:1773-1778
    • (2005) Anticancer Res , vol.25 , pp. 1773-1778
    • Molina, R.1    Auge, J.M.2    Filella, X.3
  • 21
    • 35348825431 scopus 로고    scopus 로고
    • The significance of TU M2-PK tumour marker for lung cancer diagnostics
    • Oremek G, Kukshaite R, Sapoutzis N, et al. The significance of TU M2-PK tumour marker for lung cancer diagnostics. Klin Med (Mosk) 2007;85:56-58
    • (2007) Klin Med (Mosk) , vol.85 , pp. 56-58
    • Oremek, G.1    Kukshaite, R.2    Sapoutzis, N.3
  • 22
    • 0036249158 scopus 로고    scopus 로고
    • Tumour M2-pyruvate kinase in lung cancer patients: Immunohistochemical detection and disease monitoring
    • Schneider J, Neu K, Grimm H, et al. Tumour M2-pyruvate kinase in lung cancer patients: immunohistochemical detection and disease monitoring. Anticancer Res 2002;22:311-318
    • (2002) Anticancer Res , vol.22 , pp. 311-318
    • Schneider, J.1    Neu, K.2    Grimm, H.3
  • 23
    • 34247155282 scopus 로고    scopus 로고
    • C-reactive protein levels, variation in the C-reactive protein gene, and cancer risk: The rotterdam study
    • Siemes C, Visser LE, Coebergh JW, et al. C-reactive protein levels, variation in the C-reactive protein gene, and cancer risk: the Rotterdam Study. J Clin Oncol 2006;24:5216-5222
    • (2006) J Clin Oncol , vol.24 , pp. 5216-5222
    • Siemes, C.1    Visser, L.E.2    Coebergh, J.W.3
  • 24
    • 0345059332 scopus 로고    scopus 로고
    • Tumour markers (CEA, CA 125, CYFRA 21-1, SCC and NSE) in patients with non-small cell lung cancer as an aid in histological diagnosis and prognosis. Comparison with the main clinical and pathological prognostic factors
    • Molina R, Filella X, Augé JM, et al. Tumour markers (CEA, CA 125, CYFRA 21-1, SCC and NSE) in patients with non-small cell lung cancer as an aid in histological diagnosis and prognosis. Comparison with the main clinical and pathological prognostic factors. Tumour Biol 2003;24:209-218
    • (2003) Tumour Biol , vol.24 , pp. 209-218
    • Molina, R.1    Filella, X.2    Augé, J.M.3
  • 25
    • 66449111135 scopus 로고    scopus 로고
    • Usefulness of serum tumour markers including progastrin-releasing peptide
    • Molina R, Augè JM, Bosch X, et al. Usefulness of serum tumour markers including progastrin-releasing peptide. Tumour Biol 2009;30:121-129
    • (2009) Tumour Biol , vol.30 , pp. 121-129
    • Molina, R.1    Augè, J.M.2    Bosch, X.3
  • 26
    • 0033162085 scopus 로고    scopus 로고
    • Tumour markers in lung cancer: EGTM recommendations
    • European Group on Tumour Markers
    • European Group on Tumour Markers. Tumour markers in lung cancer: EGTM recommendations. Anticancer Res 1999;19:2817-2819
    • (1999) Anticancer Res , vol.19 , pp. 2817-2819
  • 27
    • 66649116391 scopus 로고    scopus 로고
    • The efficacy of serum carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), carbohydrate antigen 19-9 (CA19-9), carbohydrate antigen 15-3 (CA15-3), alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG) levels in determining the malignancy of solitary pulmonary nodules
    • Bekci TT, Senol T, Maden E. The efficacy of serum carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), carbohydrate antigen 19-9 (CA19-9), carbohydrate antigen 15-3 (CA15-3), alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG) levels in determining the malignancy of solitary pulmonary nodules. J Int Med Res 2009;37(2):438-445
    • (2009) J Int Med Res , vol.37 , Issue.2 , pp. 438-445
    • Bekci, T.T.1    Senol, T.2    Maden, E.3
  • 28
    • 33747074100 scopus 로고    scopus 로고
    • Immunohistochemical markers of prognosis in non-small cell lung cancer: A review and proposal for a multiphase approach to marker evaluation
    • Zhu CQ, Shih W, Tsao MS. Immunohistochemical markers of prognosis in non-small cell lung cancer: a review and proposal for a multiphase approach to marker evaluation. J Clin Pathol 2006;59:790-800
    • (2006) J Clin Pathol , vol.59 , pp. 790-800
    • Zhu, C.Q.1    Shih, W.2    Tsao, M.S.3
  • 29
    • 34247891719 scopus 로고    scopus 로고
    • A translational view of the molecular pathogenesis of lung cancer
    • Sato M, Shames DS, Gazdar AF, et al. A translational view of the molecular pathogenesis of lung cancer. J Thorac Oncol 2007;2:327-343
    • (2007) J Thorac Oncol , vol.2 , pp. 327-343
    • Sato, M.1    Shames, D.S.2    Gazdar, A.F.3
  • 30
    • 58149134374 scopus 로고    scopus 로고
    • 3p22.1 and 10q22.3 deletions detected by fluorescence in situ hybridization (FISH): A potential new tool for early detection of non-small cell lung cancer (NSCLC)
    • Yendamuri S, Vaporciyan AA, Zaidi T, et al. 3p22.1 and 10q22.3 deletions detected by fluorescence in situ hybridization (FISH): a potential new tool for early detection of non-small cell lung cancer (NSCLC). J Thorac Oncol 2008;3:979-984
    • (2008) J Thorac Oncol , vol.3 , pp. 979-984
    • Yendamuri, S.1    Vaporciyan, A.A.2    Zaidi, T.3
  • 31
    • 70349388721 scopus 로고    scopus 로고
    • Understanding prognostic gene expression signatures in lung cancer
    • Zhu CQ, Pintilie M, John T, et al. Understanding prognostic gene expression signatures in lung cancer. Clin Lung Cancer 2009;10:331-340
    • (2009) Clin Lung Cancer , vol.10 , pp. 331-340
    • Zhu, C.Q.1    Pintilie, M.2    John, T.3
  • 32
    • 33746875641 scopus 로고    scopus 로고
    • A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer
    • Potti A, Mukherjee S, Petersen R, et al. A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med 2006;355:570-580
    • (2006) N Engl J Med , vol.355 , pp. 570-580
    • Potti, A.1    Mukherjee, S.2    Petersen, R.3
  • 33
    • 33750966349 scopus 로고    scopus 로고
    • Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts
    • Hayes DN, Monti S, Parmigiani G, et al. Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts. J Clin Oncol 2006;24:5079-5090
    • (2006) J Clin Oncol , vol.24 , pp. 5079-5090
    • Hayes, D.N.1    Monti, S.2    Parmigiani, G.3
  • 34
    • 0035923583 scopus 로고    scopus 로고
    • Diversity of gene expression in adenocarcinoma of the lung
    • Garber ME, Troyanskaya OG, Schluens K, et al. Diversity of gene expression in adenocarcinoma of the lung. Proc Natl Acad Sci USA 2001;98:13784-13789
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13784-13789
    • Garber, M.E.1    Troyanskaya, O.G.2    Schluens, K.3
  • 35
    • 0035923521 scopus 로고    scopus 로고
    • Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
    • Bhattacharjee A, Richards WG, Staunton J, et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci USA 2001;98:13790-13795
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13790-13795
    • Bhattacharjee, A.1    Richards, W.G.2    Staunton, J.3
  • 36
    • 33847749502 scopus 로고    scopus 로고
    • Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer
    • Spira A, Beane JE, Shah V, et al. Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat Med 2007;13:361-366
    • (2007) Nat Med , vol.13 , pp. 361-366
    • Spira, A.1    Beane, J.E.2    Shah, V.3
  • 37
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumour
    • Ramaswamy S, Ross KN, Lander ES, et al. A molecular signature of metastasis in primary solid tumour. Nat Genet 2003;33:49-54
    • (2003) Nat Genet , vol.33 , pp. 49-54
    • Ramaswamy, S.1    Ross, K.N.2    Lander, E.S.3
  • 38
    • 2342419135 scopus 로고    scopus 로고
    • Expression profiling of non-small cell lung carcinoma identifies metastatic genotypes based on lymphnode tumour burden
    • Hoang CD, D'Cunha J, Tawfic SH, et al. Expression profiling of non-small cell lung carcinoma identifies metastatic genotypes based on lymphnode tumour burden. J Thorac Cardiovasc Surg 2004;127:1332-1342
    • (2004) J Thorac Cardiovasc Surg , vol.127 , pp. 1332-1342
    • Hoang, C.D.1    D'cunha, J.2    Tawfic, S.H.3
  • 39
    • 18544365698 scopus 로고    scopus 로고
    • Gene-expression profiles predict survival of patients with lung adenocarcinoma
    • Beer DG, Kardia SL, Huang CC, et al. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 2002;8:816-824
    • (2002) Nat Med , vol.8 , pp. 816-824
    • Beer, D.G.1    Kardia, S.L.2    Huang, C.C.3
  • 40
    • 1542608359 scopus 로고    scopus 로고
    • Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction
    • Endoh H, Tomida S, Yatabe Y, et al. Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction. J Clin Oncol 2004;22:811-819
    • (2004) J Clin Oncol , vol.22 , pp. 811-819
    • Endoh, H.1    Tomida, S.2    Yatabe, Y.3
  • 41
    • 0036606299 scopus 로고    scopus 로고
    • Molecular profiling of non-small-cell lung cancer and correlation with disease-free survival
    • Wigle DA, Jurisica I, Radulovich N, et al. Molecular profiling of non-small-cell lung cancer and correlation with disease-free survival. Cancer Res 2002;62:3005-3008
    • (2002) Cancer Res , vol.62 , pp. 3005-3008
    • Wigle, D.A.1    Jurisica, I.2    Radulovich, N.3
  • 42
    • 13244289883 scopus 로고    scopus 로고
    • Joint analysis of two microarray gene-expression data sets to select lung adenocarcinoma marker genes
    • Jiang H, Deng Y, Chen HS, et al. Joint analysis of two microarray gene-expression data sets to select lung adenocarcinoma marker genes. BMC Bioinformatics 2004;5:81
    • (2004) BMC Bioinformatics , vol.5 , pp. 81
    • Jiang, H.1    Deng, Y.2    Chen, H.S.3
  • 43
    • 2442545413 scopus 로고    scopus 로고
    • A cross-study comparison of gene expression studies for the molecular classification of lung cancer
    • DOI 10.1158/1078-0432.CCR-03-0490
    • Parmigiani G, Garrett-Mayer ES, Anbazhagan R, et al. A cross-study comparison of gene-expression studies for the molecular classification of lung cancer. Clin Cancer Res 2004;10:2922-2927 (Pubitemid 38619666)
    • (2004) Clinical Cancer Research , vol.10 , Issue.9 , pp. 2922-2927
    • Parmigiani, G.1    Garrett-Mayer, E.S.2    Anbazhagan, R.3    Gabrielson, E.4
  • 44
    • 33845877973 scopus 로고    scopus 로고
    • A gene expression signature predicts survival of patients with stage i non-small cell lung cancer
    • Lu Y, Lemon W, Liu PY, et al. A gene expression signature predicts survival of patients with stage I non-small cell lung cancer. PLoS Med 2006;3:e467
    • (2006) PLoS Med , vol.3
    • Lu, Y.1    Lemon, W.2    Liu, P.Y.3
  • 45
    • 33846011470 scopus 로고    scopus 로고
    • A five-gene signature and clinical outcome in non-small-cell lung cancer
    • Chen HY, Yu SL, Chen CH, et al. A five-gene signature and clinical outcome in non-small-cell lung cancer. N Engl J Med 2007;356:11-20
    • (2007) N Engl J Med , vol.356 , pp. 11-20
    • Chen, H.Y.1    Yu, S.L.2    Chen, C.H.3
  • 46
    • 61549143718 scopus 로고    scopus 로고
    • Clinical impact of high-throughput gene expression studies in lung cancer
    • Beane J, Spira A, Lenburg ME. Clinical impact of high-throughput gene expression studies in lung cancer. J Thorac Oncol 2009;4:109-118
    • (2009) J Thorac Oncol , vol.4 , pp. 109-118
    • Beane, J.1    Spira, A.2    Lenburg, M.E.3
  • 47
    • 33748491517 scopus 로고    scopus 로고
    • The MicroArray Quality Control (MAQC) project shows inter-and intraplatform reproducibility of gene expression measurements
    • Shi L, Reil LH, Jones WD, et al. The MicroArray Quality Control (MAQC) project shows inter-and intraplatform reproducibility of gene expression measurements. Nat Biotechnol 2006;24:1151-1161
    • (2006) Nat Biotechnol , vol.24 , pp. 1151-1161
    • Shi, L.1    Reil, L.H.2    Jones, W.D.3
  • 49
    • 77349091545 scopus 로고    scopus 로고
    • Biological and clinical significance of KRAS mutations in lung cancer: An oncogenic driver that contrasts with EGFR mutation
    • Suda K, Tomizawa K, Mitsudomi T. Biological and clinical significance of KRAS mutations in lung cancer: an oncogenic driver that contrasts with EGFR mutation. Cancer Metastasis Rev 2010;29(1):49-60
    • (2010) Cancer Metastasis Rev , vol.29 , Issue.1 , pp. 49-60
    • Suda, K.1    Tomizawa, K.2    Mitsudomi, T.3
  • 50
    • 59049105640 scopus 로고    scopus 로고
    • The predictive value of epidermal growth factor receptor tests in patients with pulmonary adenocarcinoma: Review of current 'best evidence' with meta-analysis
    • Gupta R, Dastane AM, McKenna R Jr, et al. The predictive value of epidermal growth factor receptor tests in patients with pulmonary adenocarcinoma: review of current 'best evidence' with meta-analysis. Hum Pathol 2009;40:356-365
    • (2009) Hum Pathol , vol.40 , pp. 356-365
    • Gupta, R.1    Dastane, A.M.2    McKenna Jr., R.3
  • 51
    • 27244443759 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: A Southwest oncology group study
    • Hirsch FR, Varella-Garcia M, McCoy J, et al. Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: a Southwest Oncology Group Study. J Clin Oncol 2005;23:6838-6845
    • (2005) J Clin Oncol , vol.23 , pp. 6838-6845
    • Hirsch, F.R.1    Varella-Garcia, M.2    McCoy, J.3
  • 52
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361:947-957
    • (2009) N Engl J Med , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 53
    • 17644403128 scopus 로고    scopus 로고
    • Association of HER-2 overexpression with prognosis in non-small cell lung carcinoma: A metanalysis
    • Nakamura H, Kawasaki N, Taguchi M, et al. Association of HER-2 overexpression with prognosis in non-small cell lung carcinoma: a metanalysis. Cancer 2005;103:1865-1873
    • (2005) Cancer , vol.103 , pp. 1865-1873
    • Nakamura, H.1    Kawasaki, N.2    Taguchi, M.3
  • 54
    • 0031934761 scopus 로고    scopus 로고
    • Molecular abnormalities in lung cancer
    • Salgia R, Skarin AT. Molecular abnormalities in lung cancer. J Clin Oncol 1998;16:1207-1217
    • (1998) J Clin Oncol , vol.16 , pp. 1207-1217
    • Salgia, R.1    Skarin, A.T.2
  • 55
    • 0026654238 scopus 로고
    • Ras gene mutations as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis
    • Sugio K, Ishida T, Yokoyama H, et al. Ras gene mutations as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis. Cancer Res 1992;52:2903-2906
    • (1992) Cancer Res , vol.52 , pp. 2903-2906
    • Sugio, K.1    Ishida, T.2    Yokoyama, H.3
  • 56
    • 0025074419 scopus 로고
    • K-ras oncogene activation as a prognostic marker in adenocarcinoma of the lung
    • Slebos RJ, Kibbelaar RE, Dalesio O, et al. K-ras oncogene activation as a prognostic marker in adenocarcinoma of the lung. N Engl J Med 1990;323:561-565
    • (1990) N Engl J Med , vol.323 , pp. 561-565
    • Slebos, R.J.1    Kibbelaar, R.E.2    Dalesio, O.3
  • 57
    • 0032975370 scopus 로고    scopus 로고
    • Prognostic significance of K-ras codon 12 mutations in patients with resected stage i and II non-small-cell lung cancer
    • Graziano SL, Gamble GP, Newman NB, et al. Prognostic significance of K-ras codon 12 mutations in patients with resected stage I and II non-small-cell lung cancer. J Clin Oncol 1999;17:668-675
    • (1999) J Clin Oncol , vol.17 , pp. 668-675
    • Graziano, S.L.1    Gamble, G.P.2    Newman, N.B.3
  • 58
    • 65649108558 scopus 로고    scopus 로고
    • A gene expression signature associated with 'K-ras addiction' reveals regulators of EMT and tumour cell survival
    • Singh A, Greninger P, Rhodes D, et al. A gene expression signature associated with 'K-ras addiction' reveals regulators of EMT and tumour cell survival. Cancer Cell 2009;15:489-500
    • (2009) Cancer Cell , vol.15 , pp. 489-500
    • Singh, A.1    Greninger, P.2    Rhodes, D.3
  • 59
    • 57349194139 scopus 로고    scopus 로고
    • Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
    • Engelman JA, Chen L, Tan X, et al. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med 2008;14:1351-1356
    • (2008) Nat Med , vol.14 , pp. 1351-1356
    • Engelman, J.A.1    Chen, L.2    Tan, X.3
  • 60
    • 70449091786 scopus 로고    scopus 로고
    • Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
    • Barbie DA, Tamayo P, Boehm JS, et al. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature 2009;462:108-112
    • (2009) Nature , vol.462 , pp. 108-112
    • Barbie, D.A.1    Tamayo, P.2    Boehm, J.S.3
  • 61
    • 77953779015 scopus 로고    scopus 로고
    • Hepatocyte growth factor is predomintantly expressed by the carcinoma cells in non-small cell lung cancer
    • Tsa MS, Yang Y, Marcus A, et al. Hepatocyte growth factor is predomintantly expressed by the carcinoma cells in non-small cell lung cancer. Hum Pathol 2001;3257-3265
    • (2001) Hum Pathol , pp. 3257-3265
    • Tsa, M.S.1    Yang, Y.2    Marcus, A.3
  • 62
    • 0031667559 scopus 로고    scopus 로고
    • Differential expression of Met/ Hepatocyte growth factor receptor in subtypes of non-small cell lung cancer
    • Tsao MS, Liu N, Chen JR, et al. Differential expression of Met/ Hepatocyte growth factor receptor in subtypes of non-small cell lung cancer. Lung Cancer 1998;20:1-16
    • (1998) Lung Cancer , vol.20 , pp. 1-16
    • Tsao, M.S.1    Liu, N.2    Chen, J.R.3
  • 63
    • 24944468127 scopus 로고    scopus 로고
    • Overexpression of circulating c-met messenger RNA is significantly correlated with nodal stage and early recurrence in non-small cell lung cancer
    • Cheng TL, Chang MY, Huang SY, et al. Overexpression of circulating c-met messenger RNA is significantly correlated with nodal stage and early recurrence in non-small cell lung cancer. Chest 2005;128:1453-1460
    • (2005) Chest , vol.128 , pp. 1453-1460
    • Cheng, T.L.1    Chang, M.Y.2    Huang, S.Y.3
  • 64
    • 0030043970 scopus 로고    scopus 로고
    • Prognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small cell lung cancer
    • Betticher DC, Heighway J, Hasleton PS, et al. Prognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small cell lung cancer. Br J Cancer 1996;73:294-300
    • (1996) Br J Cancer , vol.73 , pp. 294-300
    • Betticher, D.C.1    Heighway, J.2    Hasleton, P.S.3
  • 65
    • 0037868819 scopus 로고    scopus 로고
    • Cyclin D1 overexpression in bronchial epithelia of patients with lung cancer is associated with smoking and predicts survival
    • Ratschiller D, Heighway J, Gugger M, et al. Cyclin D1 overexpression in bronchial epithelia of patients with lung cancer is associated with smoking and predicts survival. J Clin Oncol 2003;21:2085-2093
    • (2003) J Clin Oncol , vol.21 , pp. 2085-2093
    • Ratschiller, D.1    Heighway, J.2    Gugger, M.3
  • 66
    • 21844434717 scopus 로고    scopus 로고
    • Cell cycle related proteins as prognostic parameters in radically resected non-small cell lung cancer
    • Esposito V, Baldi A, De Luca A, et al. Cell cycle related proteins as prognostic parameters in radically resected non-small cell lung cancer. J Clin Pathol 2005;58:734-739
    • (2005) J Clin Pathol , vol.58 , pp. 734-739
    • Esposito, V.1    Baldi, A.2    De Luca, A.3
  • 67
    • 4544264923 scopus 로고    scopus 로고
    • Evaluation of immunohistochemical markers in non-small cell lung cancer by unsupervised hierarchical clustering analysis: A tissue microarray study of 284 cases and 18 markers
    • Au NH, Cheang M, Huntsman DG, et al. Evaluation of immunohistochemical markers in non-small cell lung cancer by unsupervised hierarchical clustering analysis: a tissue microarray study of 284 cases and 18 markers. J Pathol 2004;204:101-109
    • (2004) J Pathol , vol.204 , pp. 101-109
    • Au, N.H.1    Cheang, M.2    Huntsman, D.G.3
  • 68
    • 0033843716 scopus 로고    scopus 로고
    • Expression of cyclin D1, Ki-67 amd PCNA in non-small cell lung cancer: Prognostic significance and comparison with p53 and bcl-2
    • Nguyen VN, Mirejovsky P, Mirejovsky T, et al. Expression of cyclin D1, Ki-67 amd PCNA in non-small cell lung cancer: prognostic significance and comparison with p53 and bcl-2. Acta Histochem 2000;102:323-338
    • (2000) Acta Histochem , vol.102 , pp. 323-338
    • Nguyen, V.N.1    Mirejovsky, P.2    Mirejovsky, T.3
  • 69
    • 12344255903 scopus 로고    scopus 로고
    • Ki-67 expression and patients survival in lung cancer: Systematic review of the literature with meta-analysis
    • Martin B, Paesmans M, Mascaux C, et al. Ki-67 expression and patients survival in lung cancer: systematic review of the literature with meta-analysis. Br J Cancer 2004;91:2108-3025
    • (2004) Br J Cancer , vol.91 , pp. 2108-3025
    • Martin, B.1    Paesmans, M.2    Mascaux, C.3
  • 70
    • 1542388144 scopus 로고    scopus 로고
    • Significance of expression of TGF-b in pulmonary metastasis in non-small cell lung cancer tissues
    • Saji H, Nakamura H, Awut I, et al. Significance of expression of TGF-b in pulmonary metastasis in non-small cell lung cancer tissues. Ann Thorac Cardiovasc Surg 2003;92:295-300
    • (2003) Ann Thorac Cardiovasc Surg , vol.92 , pp. 295-300
    • Saji, H.1    Nakamura, H.2    Awut, I.3
  • 71
    • 0037106265 scopus 로고    scopus 로고
    • Clinical significance of p21 expression in non-small cell lung cancer
    • Shoji T, Tanaka F, Takata T, et al. Clinical significance of p21 expression in non-small cell lung cancer. J Clin Oncol 2002;20:3865-3871
    • (2002) J Clin Oncol , vol.20 , pp. 3865-3871
    • Shoji, T.1    Tanaka, F.2    Takata, T.3
  • 72
    • 13844275550 scopus 로고    scopus 로고
    • Absense of prognostic significance of p21 (WAF1/CIP1) protein expression in non-small cell lung cancer
    • Dworakowska D, Jassem E, Jassem J, et al. Absense of prognostic significance of p21 (WAF1/CIP1) protein expression in non-small cell lung cancer. Acta oncol 2005;44:75-79
    • (2005) Acta Oncol , vol.44 , pp. 75-79
    • Dworakowska, D.1    Jassem, E.2    Jassem, J.3
  • 73
    • 0034848442 scopus 로고    scopus 로고
    • Reduced expression of cell-cycle regulator p27(Kip1) correlates with a shortened survival in non-small cell lung cancer
    • Tsukamoto S, Sugio K, Sakada T, et al. Reduced expression of cell-cycle regulator p27(Kip1) correlates with a shortened survival in non-small cell lung cancer. Lung Cancer 2001;34:83-90
    • (2001) Lung Cancer , vol.34 , pp. 83-90
    • Tsukamoto, S.1    Sugio, K.2    Sakada, T.3
  • 74
    • 14444268041 scopus 로고    scopus 로고
    • Prognostic role of the cicli-dependent kinase inhibitor p27 in non-small cell lung lung cancer
    • Esposito V, Baldi A, De Luca A, et al. Prognostic role of the cicli-dependent kinase inhibitor p27 in non-small cell lung lung cancer. Cancer Res 1997;57:3381-3385
    • (1997) Cancer Res , vol.57 , pp. 3381-3385
    • Esposito, V.1    Baldi, A.2    De Luca, A.3
  • 75
    • 9144243525 scopus 로고    scopus 로고
    • Analysis of cell cycle regulator proteins in non-small cell lung cancer
    • Esposito V, Baldi A, Tonini G, et al. Analysis of cell cycle regulator proteins in non-small cell lung cancer. J Clin Pathol 2004;57:58-63
    • (2004) J Clin Pathol , vol.57 , pp. 58-63
    • Esposito, V.1    Baldi, A.2    Tonini, G.3
  • 76
    • 0037307872 scopus 로고    scopus 로고
    • Prognostic prediction of the immunohistochemical expression of p53 and p16 in resected non-small cell lung cancer
    • Cheng YL, Lee SC, Harn HJ, et al. Prognostic prediction of the immunohistochemical expression of p53 and p16 in resected non-small cell lung cancer. Eur J Cardiothoracic Surg 2003;23:221-228
    • (2003) Eur J Cardiothoracic Surg , vol.23 , pp. 221-228
    • Cheng, Y.L.1    Lee, S.C.2    Harn, H.J.3
  • 77
    • 0030989021 scopus 로고    scopus 로고
    • Altered retino blastoma protein expression in nonsmall cell lung cancer: Its synergistic effects with altered ras and p53 protein status on prognosis
    • Dosaka-Akita H, Hu SX, Fujino M, et al. Altered retino blastoma protein expression in nonsmall cell lung cancer: its synergistic effects with altered ras and p53 protein status on prognosis. Cancer 1997;79:1329-1337
    • (1997) Cancer , vol.79 , pp. 1329-1337
    • Dosaka-Akita, H.1    Hu, S.X.2    Fujino, M.3
  • 78
    • 19944427869 scopus 로고    scopus 로고
    • Prognostic implications of molecular and immunohistochemical profiles of the Rb and p53 cell cycle regulatory pathways in primary non-small cell lung carcinoma
    • Burke L, Flieder DB, Guinee DG, et al. Prognostic implications of molecular and immunohistochemical profiles of the Rb and p53 cell cycle regulatory pathways in primary non-small cell lung carcinoma. Clin Cancer Res 2005;11:232-241
    • (2005) Clin Cancer Res , vol.11 , pp. 232-241
    • Burke, L.1    Flieder, D.B.2    Guinee, D.G.3
  • 79
    • 0035144783 scopus 로고    scopus 로고
    • Loss of p16 and/or pRb protein expression in NSCLC. An immunohistochemical and prognostic study
    • Chen JT, Chen YC, Chen CY, et al. Loss of p16 and/or pRb protein expression in NSCLC. An immunohistochemical and prognostic study. Lung Cancer 2001;31:163-170
    • (2001) Lung Cancer , vol.31 , pp. 163-170
    • Chen, J.T.1    Chen, Y.C.2    Chen, C.Y.3
  • 80
    • 0031841384 scopus 로고    scopus 로고
    • IARC database of p53 gene mutations in human tumours and cell lines: Updated compilation, revised formats and new visualisation tools
    • Hainaut P, Hernandez T, Robinson A, et al. IARC database of p53 gene mutations in human tumours and cell lines: updated compilation, revised formats and new visualisation tools. Nucleic Acids Res 1998;26:205-213
    • (1998) Nucleic Acids Res , vol.26 , pp. 205-213
    • Hainaut, P.1    Hernandez, T.2    Robinson, A.3
  • 81
    • 0024452546 scopus 로고
    • P53: A frequent target for genetic abnormalities in lung cancer
    • Takahashi T, Nau MM, Chiba I, et al. p53: a frequent target for genetic abnormalities in lung cancer. Science 1989;246:491-494
    • (1989) Science , vol.246 , pp. 491-494
    • Takahashi, T.1    Nau, M.M.2    Chiba, I.3
  • 82
    • 20444374483 scopus 로고    scopus 로고
    • Circulating tumour-derived DNA and RNA markers in blood: A tool for early detection, diagnostics, and follow-up?
    • Bremnes RM, Sirera R, Camps C. Circulating tumour-derived DNA and RNA markers in blood: a tool for early detection, diagnostics, and follow-up? Lung Cancer 2005;49:1-12
    • (2005) Lung Cancer , vol.49 , pp. 1-12
    • Bremnes, R.M.1    Sirera, R.2    Camps, C.3
  • 83
    • 0345687975 scopus 로고    scopus 로고
    • Detecting lung cancer in plasma with the use of multiple genetic markers
    • Andriani F, Conte D, Mastrangelo T, et al. Detecting lung cancer in plasma with the use of multiple genetic markers. Int J Cancer 2004;108:91-96
    • (2004) Int J Cancer , vol.108 , pp. 91-96
    • Andriani, F.1    Conte, D.2    Mastrangelo, T.3
  • 84
    • 0042964835 scopus 로고    scopus 로고
    • P53 mutations and survival in stage i non-small-cell lung cancer: Results of a prospective study
    • Ahrendt SA, Hu Y, Buta M, et al. p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study. J Natl Cancer Inst 2003;95:961-970
    • (2003) J Natl Cancer Inst , vol.95 , pp. 961-970
    • Ahrendt, S.A.1    Hu, Y.2    Buta, M.3
  • 85
    • 10744230829 scopus 로고    scopus 로고
    • MDM2 gene amplification: A new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC)
    • Dworakowska D, Jassem E, Jassem J, et al. MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC). Lung Cancer 2004;43:285-295
    • (2004) Lung Cancer , vol.43 , pp. 285-295
    • Dworakowska, D.1    Jassem, E.2    Jassem, J.3
  • 87
    • 0842286954 scopus 로고    scopus 로고
    • Prognostic value of immunohistochemical expression of p53, bax, Bcl-2 and Bcl-XL in resected non-small cell lung cancers
    • Groeger AM, Esposito V, De Luca A, et al. Prognostic value of immunohistochemical expression of p53, bax, Bcl-2 and Bcl-XL in resected non-small cell lung cancers. Histopathology 2004;44:54-63
    • (2004) Histopathology , vol.44 , pp. 54-63
    • Groeger, A.M.1    Esposito, V.2    De Luca, A.3
  • 88
    • 0035985813 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of apoptosis-regulated proteins, Bcl-2 and Bax, in resected non-small-cell lung cancers
    • Hanaoka T, Nakayama J, Haniuda M, et al. Immunohistochemical demonstration of apoptosis-regulated proteins, Bcl-2 and Bax, in resected non-small-cell lung cancers. Int J Clin Oncol 2002;7:152-158
    • (2002) Int J Clin Oncol , vol.7 , pp. 152-158
    • Hanaoka, T.1    Nakayama, J.2    Haniuda, M.3
  • 89
    • 18044373030 scopus 로고    scopus 로고
    • Clinical application of biological markers for treatments of resectable non-small-cell lung cancer
    • Huang C, Liu D, Masuya D, et al. Clinical application of biological markers for treatments of resectable non-small-cell lung cancer. Br J Cancer 2005;92:1231-1239
    • (2005) Br J Cancer , vol.92 , pp. 1231-1239
    • Huang, C.1    Liu, D.2    Masuya, D.3
  • 90
    • 4544250024 scopus 로고    scopus 로고
    • Gene-promoter hypermethylation as a biomarker in lung cancer
    • Belinsky SA. Gene-promoter hypermethylation as a biomarker in lung cancer. Nat Rev Cancer 2004;4:707-717
    • (2004) Nat Rev Cancer , vol.4 , pp. 707-717
    • Belinsky, S.A.1
  • 91
    • 0037068329 scopus 로고    scopus 로고
    • DNA methylation analysis: A powerful new tool for lung cancer diagnosis
    • Tsou JA, Hagen JA, Carpenter CL, et al. DNA methylation analysis: a powerful new tool for lung cancer diagnosis. Oncogene 2002;21:5450-5461
    • (2002) Oncogene , vol.21 , pp. 5450-5461
    • Tsou, J.A.1    Hagen, J.A.2    Carpenter, C.L.3
  • 92
    • 0035132145 scopus 로고    scopus 로고
    • Aberrant promoter methylation of multiple genes in nonsmall cell lung cancers
    • Zochbauer-Muller S, Fong KM, Virmani AK, et al. Aberrant promoter methylation of multiple genes in nonsmall cell lung cancers. Cancer Res 2001;61:249-255
    • (2001) Cancer Res , vol.61 , pp. 249-255
    • Zochbauer-Muller, S.1    Fong, K.M.2    Virmani, A.K.3
  • 93
    • 0033607147 scopus 로고    scopus 로고
    • In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis
    • Nuovo GJ, Plaia TW, Belinsky SA, et al. In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis. Proc Natl Acad Sci USA 1999;96:12754-12759
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12754-12759
    • Nuovo, G.J.1    Plaia, T.W.2    Belinsky, S.A.3
  • 94
    • 33645521023 scopus 로고    scopus 로고
    • Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort
    • Belinsky SA, Liechty KC, Gentry FD, et al. Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. Cancer Res 2006;66:3338-3344
    • (2006) Cancer Res , vol.66 , pp. 3338-3344
    • Belinsky, S.A.1    Liechty, K.C.2    Gentry, F.D.3
  • 95
    • 35648953334 scopus 로고    scopus 로고
    • Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma
    • Han-Shui Hsu MD, Tsz-Pei Chen MS, Chein-Hui Hung MS, et al. Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma. Cancer 2007;110:2019-2026
    • (2007) Cancer , vol.110 , pp. 2019-2026
    • Han-Shui Hsu, M.D.1    Tsz-Pei Chen, M.S.2    Chein-Hui Hung, M.S.3
  • 96
    • 32044438696 scopus 로고    scopus 로고
    • Aberrant DNA methylation of E-Cadherin and p16 genes in rat lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine
    • DOI 10.1002/mc.20162
    • Kato A, Shimizu K, Shimoichi Y, et al. Aberrant DNA methylation of E-cadherin and p16 genes in rat lung adenocarcinomas induced by Nnitrosobis( 2-hydroxypropyl)amine. Mol Carcinog 2006;45:106-111 (Pubitemid 43202583)
    • (2006) Molecular Carcinogenesis , vol.45 , Issue.2 , pp. 106-111
    • Kato, A.1    Shimizu, K.2    Shimoichi, Y.3    Fujii, H.4    Honoki, K.5    Tsujiuchi, T.6
  • 97
    • 0042563143 scopus 로고    scopus 로고
    • Promoter hypermethylation of tumour suppressor and tumour-related genes in non-small cell lung cancers
    • Yanagawa N, Tamura G, Oizumi H, et al. Promoter hypermethylation of tumour suppressor and tumour-related genes in non-small cell lung cancers. Cancer Sci 2003;94:589-592
    • (2003) Cancer Sci , vol.94 , pp. 589-592
    • Yanagawa, N.1    Tamura, G.2    Oizumi, H.3
  • 98
    • 12244297095 scopus 로고    scopus 로고
    • Quantitative O(6)-methylguanine DNA methyltransferase methylation analysis in curatively resected non-small cell lung cancer: Associations with clinical outcome
    • Brabender J, Usadel H, Metzger R, et al. Quantitative O(6)-methylguanine DNA methyltransferase methylation analysis in curatively resected non-small cell lung cancer: associations with clinical outcome. Clin Cancer Res 2003;9:223-227
    • (2003) Clin Cancer Res , vol.9 , pp. 223-227
    • Brabender, J.1    Usadel, H.2    Metzger, R.3
  • 99
    • 24644502624 scopus 로고    scopus 로고
    • Methylation discriminators in NSCLC identified by a microarray based approach
    • Field JK, Liloglou T, Warrak S, et al. Methylation discriminators in NSCLC identified by a microarray based approach. Int J Oncol 2005;27:105-111
    • (2005) Int J Oncol , vol.27 , pp. 105-111
    • Field, J.K.1    Liloglou, T.2    Warrak, S.3
  • 100
    • 33947629246 scopus 로고    scopus 로고
    • Aberrant DNA methylation of OLIG1, a novel prognostic factor in non-small cell lung cancer
    • Brena RM, Morrison C, Liyanarachchi S, et al. Aberrant DNA methylation of OLIG1, a novel prognostic factor in non-small cell lung cancer. PLoS Med 2007;4:e108
    • (2007) PLoS Med , vol.4
    • Brena, R.M.1    Morrison, C.2    Liyanarachchi, S.3
  • 101
    • 0033577058 scopus 로고    scopus 로고
    • Molecular detection of tumour cells in bronchoalveolar lavage fluid from patients with early stage lung cancer
    • Ahrendt SA, Chow JT, Xu LH, et al. Molecular detection of tumour cells in bronchoalveolar lavage fluid from patients with early stage lung cancer. J Natl Cancer Inst 1999;91:332-339
    • (1999) J Natl Cancer Inst , vol.91 , pp. 332-339
    • Ahrendt, S.A.1    Chow, J.T.2    Xu, L.H.3
  • 102
    • 67649399383 scopus 로고    scopus 로고
    • Potential uses of microRNA in lung cancer diagnosis, prognosis and therapy
    • Wang QZ, Xu W, Habib N. Potential uses of microRNA in lung cancer diagnosis, prognosis and therapy. Curr Cancer Drug Target 2009;9:572-594
    • (2009) Curr Cancer Drug Target , vol.9 , pp. 572-594
    • Wang, Q.Z.1    Xu, W.2    Habib, N.3
  • 103
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci 2004;101:2999-3004
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3
  • 104
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumours defines cancer gene targets
    • Volinia S, Calin GA, Liu CG, et al. A microRNA expression signature of human solid tumours defines cancer gene targets. Proc Natl Acad Sci USA 2006;103:2257-2261
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3
  • 105
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006;6:857-866
    • (2006) Nat Rev Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 106
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA- 21 targets tumour suppressor genes in invasion and metastasis
    • Zhu S, Wu H, Wu F, et al. MicroRNA- 21 targets tumour suppressor genes in invasion and metastasis. Cell Res 2008;18:350-359
    • (2008) Cell Res , vol.18 , pp. 350-359
    • Zhu, S.1    Wu, H.2    Wu, F.3
  • 107
    • 48749122914 scopus 로고    scopus 로고
    • Circulating microRNAs as stable blood-based markers for cancer detection
    • Mitchell PS, Parkin RK, Kroh EM, et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci USA 2008;105:10513-10518
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10513-10518
    • Mitchell, P.S.1    Parkin, R.K.2    Kroh, E.M.3
  • 108
    • 42449098100 scopus 로고    scopus 로고
    • Normalization of microRNA expression levels in quantitative RT-PCR assays: Identification of suitable reference RNA targets in normal and cancerous human solid tissues
    • Peltier HJ, Latham GJ. Normalization of microRNA expression levels in quantitative RT-PCR assays: identification of suitable reference RNA targets in normal and cancerous human solid tissues. RNA 2008;14:844-852
    • (2008) RNA , vol.14 , pp. 844-852
    • Peltier, H.J.1    Latham, G.J.2
  • 109
    • 61449208911 scopus 로고    scopus 로고
    • Downregulation of microRNA expression in the lungs of rat exposed to cigarette smoke
    • Izzotti A, Calin GA, Arri P, et al. Downregulation of microRNA expression in the lungs of rat exposed to cigarette smoke. FASEB J 2009;23:806-812
    • (2009) FASEB J , vol.23 , pp. 806-812
    • Izzotti, A.1    Calin, G.A.2    Arri, P.3
  • 110
    • 33644819964 scopus 로고    scopus 로고
    • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
    • Yanaihara N, Caplen N, Bowman E, et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 2006;9(3):189-198
    • (2006) Cancer Cell , vol.9 , Issue.3 , pp. 189-198
    • Yanaihara, N.1    Caplen, N.2    Bowman, E.3
  • 111
    • 65349166324 scopus 로고    scopus 로고
    • Diagnostic assay based on has-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma
    • Lebanony D, Benjamin H, Gilad S, et al. Diagnostic assay based on has-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma. J Clin Oncol 2009;27:2030-2037
    • (2009) J Clin Oncol , vol.27 , pp. 2030-2037
    • Lebanony, D.1    Benjamin, H.2    Gilad, S.3
  • 112
    • 37349096992 scopus 로고    scopus 로고
    • MicroRNA signature predicts survival and relapse in lung cancer
    • Yu SL, Chen HY, Chang GC, et al. MicroRNA signature predicts survival and relapse in lung cancer. Cancer Cell 2008;13:48-57
    • (2008) Cancer Cell , vol.13 , pp. 48-57
    • Yu, S.L.1    Chen, H.Y.2    Chang, G.C.3
  • 113
    • 35748956868 scopus 로고    scopus 로고
    • Let-7 MicroRNA expression is reduced in bronchioloalveolar carcinoma, a non-invasive carcinoma, and is not correlated with prognosis
    • Inamura K, Togashi Y, Nomura K, et al. Let-7 MicroRNA expression is reduced in bronchioloalveolar carcinoma, a non-invasive carcinoma, and is not correlated with prognosis. Lung Cancer 2007;58:392-396
    • (2007) Lung Cancer , vol.58 , pp. 392-396
    • Inamura, K.1    Togashi, Y.2    Nomura, K.3
  • 114
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 MicroRNA family
    • Johnson SM, Grosshans H, Shingara J, et al. RAS is regulated by the let-7 MicroRNA family. Cell 2005;120:635-647
    • (2005) Cell , vol.120 , pp. 635-647
    • Johnson, S.M.1    Grosshans, H.2    Shingara, J.3
  • 115
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 MicroRNAs in human lung cancers in association with shortened postoperative survival
    • Takamizawa J, Konishi H, Yanagisawa K, et al. Reduced expression of the let-7 MicroRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 2004;64:3753-3756
    • (2004) Cancer Res , vol.64 , pp. 3753-3756
    • Takamizawa, J.1    Konishi, H.2    Yanagisawa, K.3
  • 116
    • 34447632218 scopus 로고    scopus 로고
    • Role of dicer and Drosha for endothelial microRNA expression and angiogenesis
    • Kuehbacher A, Urbich C, Zeiher AM, et al. Role of dicer and Drosha for endothelial microRNA expression and angiogenesis. Circ Res 2007;101:59-68
    • (2007) Circ Res , vol.101 , pp. 59-68
    • Kuehbacher, A.1    Urbich, C.2    Zeiher, A.M.3
  • 117
    • 55549127406 scopus 로고    scopus 로고
    • Let-7 regulates DICER expression and constitutes a negative feedback loop
    • Tokumaru S, Suzuki M, Yamada H, et al. Let-7 regulates DICER expression and constitutes a negative feedback loop. Carcinogenesis 2008;29:2073-2077
    • (2008) Carcinogenesis , vol.29 , pp. 2073-2077
    • Tokumaru, S.1    Suzuki, M.2    Yamada, H.3
  • 118
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster, miR 17-92 is overexpressed in human lung cancers and enhances cell proliferation
    • Hayashita Y, Osada H, Tatematsu Y, et al. A polycistronic microRNA cluster, miR 17-92 is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005;65:9628-9632
    • (2005) Cancer Res , vol.65 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3
  • 119
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumour suppressors
    • Zhang B, Pan X, Cobb GP, et al. MicroRNAs as oncogenes and tumour suppressors. Dev Biol 2007;302:1-12
    • (2007) Dev Biol , vol.302 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3
  • 120
    • 33749507943 scopus 로고    scopus 로고
    • A Small piece in the cancer puzzle: MicroRNAs as tumour suppressors and oncogenes
    • Kent OA, Mendell JT. A Small piece in the cancer puzzle: microRNAs as tumour suppressors and oncogenes. Oncogene 2006;25:6188-6196
    • (2006) Oncogene , vol.25 , pp. 6188-6196
    • Kent, O.A.1    Mendell, J.T.2
  • 121
    • 59649093464 scopus 로고    scopus 로고
    • Evolution of microRNAs expression during human bronchial squamous carcinogenesis
    • Mascaux C, Laes JF, Anthoine G, et al. Evolution of microRNAs expression during human bronchial squamous carcinogenesis. Eur Respir J 2009;32:352-359
    • (2009) Eur Respir J , vol.32 , pp. 352-359
    • Mascaux, C.1    Laes, J.F.2    Anthoine, G.3
  • 122
    • 33847107236 scopus 로고    scopus 로고
    • DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer
    • Zheng Z, Chen T, Li X, et al. DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer. N Engl J Med 2007;356:800-808
    • (2007) N Engl J Med , vol.356 , pp. 800-808
    • Zheng, Z.1    Chen, T.2    Li, X.3
  • 123
    • 33748435058 scopus 로고    scopus 로고
    • DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy
    • Olaussen KA, Dunant A, Fouret P, et al. DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med 2006;355:983-991
    • (2006) N Engl J Med , vol.355 , pp. 983-991
    • Olaussen, K.A.1    Dunant, A.2    Fouret, P.3
  • 124
    • 34447573875 scopus 로고    scopus 로고
    • Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: A phase III trial in non-small-cell lung cancer
    • Cobo M, Isla D, Massuti B, et al. Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in non-small-cell lung cancer. J Clin Oncol 2007;25:2747-2754
    • (2007) J Clin Oncol , vol.25 , pp. 2747-2754
    • Cobo, M.1    Isla, D.2    Massuti, B.3
  • 126
    • 0033590626 scopus 로고    scopus 로고
    • Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma
    • Wistuba II, Behrens C, Milchgrub S, et al. Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma. Oncogene 1999;18:643-650
    • (1999) Oncogene , vol.18 , pp. 643-650
    • Wistuba, I.I.1    Behrens, C.2    Milchgrub, S.3
  • 127
    • 0034282535 scopus 로고    scopus 로고
    • Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering
    • Girard L, Zochbauer-Müller S, Virmani AK, et al. Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering. Cancer Res 2000;60:4894-4906
    • (2000) Cancer Res , vol.60 , pp. 4894-4906
    • Girard, L.1    Zochbauer-Müller, S.2    Virmani, A.K.3
  • 128
    • 25444439612 scopus 로고    scopus 로고
    • Genome-wide loss of heterozygosity and its clinical associations in non small cell lung cancer
    • Tseng RC, Chang JW, Hsien FJ, et al. Genome-wide loss of heterozygosity and its clinical associations in non small cell lung cancer. Int J Cancer 2005;117:241-247
    • (2005) Int J Cancer , vol.117 , pp. 241-247
    • Tseng, R.C.1    Chang, J.W.2    Hsien, F.J.3
  • 129
    • 19244370711 scopus 로고    scopus 로고
    • High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints
    • Wistuba I, Behrens C, Virmani AK, et al. High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res 2000;60:1949-1960
    • (2000) Cancer Res , vol.60 , pp. 1949-1960
    • Wistuba, I.1    Behrens, C.2    Virmani, A.K.3
  • 130
    • 33644877818 scopus 로고    scopus 로고
    • BJ-TSA-9, a novel human tumour-specific gene, has potential as a biomarker of lung cancer
    • Li Y, Dong X, Yin Y, et al. BJ-TSA-9, a novel human tumour-specific gene, has potential as a biomarker of lung cancer. Neoplasia 2005;7:1073-1080
    • (2005) Neoplasia , vol.7 , pp. 1073-1080
    • Li, Y.1    Dong, X.2    Yin, Y.3
  • 131
    • 0035865985 scopus 로고    scopus 로고
    • Isolation of a novel human lung-specific gene, LUNX, a potential molecular marker for detection of micrometastasis in non-smallcell lung cancer
    • Iwao K, Watanabe T, Fujiwara Y, et al. Isolation of a novel human lung-specific gene, LUNX, a potential molecular marker for detection of micrometastasis in non-smallcell lung cancer. Int J Cancer 2001;91(4):433-437
    • (2001) Int J Cancer , vol.91 , Issue.4 , pp. 433-437
    • Iwao, K.1    Watanabe, T.2    Fujiwara, Y.3
  • 132
    • 70349189541 scopus 로고    scopus 로고
    • Genomic and proteomic biomarkers for cancer: A multitude of opportunities
    • Tainsky MA. Genomic and proteomic biomarkers for cancer: a multitude of opportunities. Biochim Biophys Acta 2009;1796:176-193
    • (2009) Biochim Biophys Acta , vol.1796 , pp. 176-193
    • Tainsky, M.A.1
  • 133
    • 0016168626 scopus 로고
    • Two-dimensional acrylamide gel electrophoresis of cancer-patient serum proteins
    • Wright GL Jr. Two-dimensional acrylamide gel electrophoresis of cancer-patient serum proteins. Ann Clin Lab Sci 1974;4:281-293
    • (1974) Ann Clin Lab Sci , vol.4 , pp. 281-293
    • Wright Jr., G.L.1
  • 134
    • 0036468595 scopus 로고    scopus 로고
    • Two-dimensional gel electrophoresis: Recent advances in sample preparation, detection and quantitation
    • Lilley KS, Rassaq A, Dupree P. Two-dimensional gel electrophoresis: recent advances in sample preparation, detection and quantitation. Curr Opin Chem Biol 2002;6:46-50
    • (2002) Curr Opin Chem Biol , vol.6 , pp. 46-50
    • Lilley, K.S.1    Rassaq, A.2    Dupree, P.3
  • 135
    • 0028804205 scopus 로고
    • Lung tumour cells: A multivariate approach to cell classification using two-dimensional protein pattern
    • Schmid HR, Schmitter D, Blum P, et al. Lung tumour cells: a multivariate approach to cell classification using two-dimensional protein pattern. Electrophoresis 1995;16:1961-1968
    • (1995) Electrophoresis , vol.16 , pp. 1961-1968
    • Schmid, H.R.1    Schmitter, D.2    Blum, P.3
  • 136
    • 0035992398 scopus 로고    scopus 로고
    • Proteomic analysis of lung adenocarcinoma: Identification of a highly expressed set of proteins in tumours
    • Chen G, Gharib TG, Huang CC, et al. Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumours. Clin Cancer Res 2002;8:2298-2305
    • (2002) Clin Cancer Res , vol.8 , pp. 2298-2305
    • Chen, G.1    Gharib, T.G.2    Huang, C.C.3
  • 137
    • 0040746269 scopus 로고    scopus 로고
    • A database of protein expression in lung cancer
    • Oh JM, Brichory F, Puravs E, et al. A database of protein expression in lung cancer. Proteomics 2001;1:1303-1319
    • (2001) Proteomics , vol.1 , pp. 1303-1319
    • Oh, J.M.1    Brichory, F.2    Puravs, E.3
  • 138
    • 2942529235 scopus 로고    scopus 로고
    • Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy
    • Oh P, Li Y, Yu J, et al. Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy. Nature 2004;429:629-635
    • (2004) Nature , vol.429 , pp. 629-635
    • Oh, P.1    Li, Y.2    Yu, J.3
  • 139
    • 0343376097 scopus 로고    scopus 로고
    • Difference gel electrophoresis: A single gel method for detecting changes in protein extracts
    • Unlu M, Morgan ME, Minden JS. Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Electrophoresis 1997;18:2071-2077
    • (1997) Electrophoresis , vol.18 , pp. 2071-2077
    • Unlu, M.1    Morgan, M.E.2    Minden, J.S.3
  • 140
    • 34547572949 scopus 로고    scopus 로고
    • Is proteomics the new genomics?
    • Cox J, Mann M. Is proteomics the new genomics? Cell 2007;130:395-398
    • (2007) Cell , vol.130 , pp. 395-398
    • Cox, J.1    Mann, M.2
  • 141
    • 0041735992 scopus 로고    scopus 로고
    • Proteomic patterns of tumour subsets in non-small-cell lung cancer
    • Yanagisawa K, Shyr Y, Xu BJ, et al. Proteomic patterns of tumour subsets in non-small-cell lung cancer. Lancet 2003;362:433-439
    • (2003) Lancet , vol.362 , pp. 433-439
    • Yanagisawa, K.1    Shyr, Y.2    Xu, B.J.3
  • 142
    • 34247170626 scopus 로고    scopus 로고
    • Proteomics-based identification of secreted protein dihydrodiol dehydrogenase as a novel serum markers of nonsmall cell lung cancer
    • Huang LJ, Chen SX, Huang Y, et al. Proteomics-based identification of secreted protein dihydrodiol dehydrogenase as a novel serum markers of nonsmall cell lung cancer. Lung Cancer 2006;54:87-94
    • (2006) Lung Cancer , vol.54 , pp. 87-94
    • Huang, L.J.1    Chen, S.X.2    Huang, Y.3
  • 143
    • 1242339545 scopus 로고    scopus 로고
    • Proteomic analysis of lung biopsies. differential protein expression profile between peritumoural and tumoural tissue
    • Alfonso P, Catala M, Rico-Morales ML, et al. Proteomic analysis of lung biopsies. differential protein expression profile between peritumoural and tumoural tissue. Proteomics 2004;4:442-447
    • (2004) Proteomics , vol.4 , pp. 442-447
    • Alfonso, P.1    Catala, M.2    Rico-Morales, M.L.3
  • 144
    • 0037683738 scopus 로고    scopus 로고
    • Discovery of distinct protein profiles specific for lung tumours and pre-malignant lung lesions by SELDI mass spectrometry
    • Zhukov TA, Johanson RA, Cantor AB, et al. Discovery of distinct protein profiles specific for lung tumours and pre-malignant lung lesions by SELDI mass spectrometry. Lung Cancer 2003;40:267-279
    • (2003) Lung Cancer , vol.40 , pp. 267-279
    • Zhukov, T.A.1    Johanson, R.A.2    Cantor, A.B.3
  • 145
    • 2542640080 scopus 로고    scopus 로고
    • Mass spectrometry as a diagnostic and a cancer biomarker discovery tool:Opportunities and potential
    • Diamandis EP. Mass spectrometry as a diagnostic and a cancer biomarker discovery tool: opportunities and potential. Mol Cell Proteomics 2004;3(4):367-378
    • (2004) Mol Cell Proteomics , vol.3 , Issue.4 , pp. 367-378
    • Diamandis, E.P.1
  • 146
    • 33750456480 scopus 로고    scopus 로고
    • Reverse phase protein array: Validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells
    • Tibes R, Qiu Y, Lu Y, et al. Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells. Mol Cancer Ther 2006;5:2512-2521
    • (2006) Mol Cancer Ther , vol.5 , pp. 2512-2521
    • Tibes, R.1    Qiu, Y.2    Lu, Y.3
  • 147
    • 13444280261 scopus 로고    scopus 로고
    • Protein microarrays as tools for functional proteomics
    • LaBaer J, Ramachandran N. Protein microarrays as tools for functional proteomics. Curr Opin Chem Biol 2005;9:14-19
    • (2005) Curr Opin Chem Biol , vol.9 , pp. 14-19
    • Labaer, J.1    Ramachandran, N.2
  • 148
    • 39749121336 scopus 로고    scopus 로고
    • Integral protein microarrays for the identification of lung cancer antigens in sera that induce a humoral immune response
    • Madoz-Gurpide J, Kuick R, Wang H, et al. Integral protein microarrays for the identification of lung cancer antigens in sera that induce a humoral immune response. Mol Cell Proteomics 2007;7:268-281
    • (2007) Mol Cell Proteomics , vol.7 , pp. 268-281
    • Madoz-Gurpide, J.1    Kuick, R.2    Wang, H.3
  • 149
    • 74049115774 scopus 로고    scopus 로고
    • Mass spectrometry-based label free quantitative proteomics
    • [Epub ahead of print]
    • Zhu W, Smith JW, Huang CM. Mass spectrometry-based label free quantitative proteomics. J Biomed Biotechnol 2010;2010:840518. [Epub ahead of print]
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 840518
    • Zhu, W.1    Smith, J.W.2    Huang, C.M.3
  • 150
    • 34249310279 scopus 로고    scopus 로고
    • Proteomic approaches for serum biomarker discovery in cancer
    • Maurya P, Meleady P, Dowling P, et al. Proteomic approaches for serum biomarker discovery in cancer. Anticancer Res 2007;27:1247-1255
    • (2007) Anticancer Res , vol.27 , pp. 1247-1255
    • Maurya, P.1    Meleady, P.2    Dowling, P.3
  • 151
    • 0036399228 scopus 로고    scopus 로고
    • Shotgun proteomics and biomarker discovery
    • McDonald WH, Yates JR III. Shotgun proteomics and biomarker discovery. Dis Markers 2002;18:99-105
    • (2002) Dis Markers , vol.18 , pp. 99-105
    • McDonald, W.H.1    Yates III, J.R.2
  • 152
    • 31644438577 scopus 로고    scopus 로고
    • Large scale protein profiling by combination of protein fractionation and multidimensional protein identification technology (MUDPIT)
    • Chen EI, Hewel J, Felding-Habermann B, et al. Large scale protein profiling by combination of protein fractionation and multidimensional protein identification technology (MUDPIT). Mol Cell Proteomics 2006;5:53-56
    • (2006) Mol Cell Proteomics , vol.5 , pp. 53-56
    • Chen, E.I.1    Hewel, J.2    Felding-Habermann, B.3
  • 153
    • 16344369038 scopus 로고    scopus 로고
    • Clinical-scale high-throughput human plasma proteome analysis: Lung adenocarcinoma
    • Fujii K, Nakano T, Kanazawa M, et al. Clinical-scale high-throughput human plasma proteome analysis: lung adenocarcinoma. Proteomics 2005;5:1150-1159
    • (2005) Proteomics , vol.5 , pp. 1150-1159
    • Fujii, K.1    Nakano, T.2    Kanazawa, M.3
  • 154
    • 65449150181 scopus 로고    scopus 로고
    • MRM screening/ biomarker discovery with linear ion trap MS: A library of human cancer-specific peptides
    • Yang X, Lazar IM. MRM screening/ biomarker discovery with linear ion trap MS: a library of human cancer-specific peptides. BMC Cancer 2009;9:96
    • (2009) BMC Cancer , vol.9 , pp. 96
    • Yang, X.1    Lazar, I.M.2
  • 156
    • 33645721632 scopus 로고    scopus 로고
    • Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins
    • Anderson L, Hunter CL. Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins. Mol Cell Proteomics 2006;5:573-588
    • (2006) Mol Cell Proteomics , vol.5 , pp. 573-588
    • Anderson, L.1    Hunter, C.L.2
  • 157
    • 38349068918 scopus 로고    scopus 로고
    • Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry, and stable isotope dilution
    • Keshishian H, Addona T, Burgess M, et al. Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry, and stable isotope dilution. Mol Cell Proteomics 2007;6:2212-2229
    • (2007) Mol Cell Proteomics , vol.6 , pp. 2212-2229
    • Keshishian, H.1    Addona, T.2    Burgess, M.3
  • 158
    • 0036849944 scopus 로고    scopus 로고
    • The influence of dendritic cell infiltration and vascular endothelial growth factor expression on the prognosis of non-small cell lung cancer
    • Inoshima N, Nakanishi Y, Minami T, et al. The influence of dendritic cell infiltration and vascular endothelial growth factor expression on the prognosis of non-small cell lung cancer. Clin Cancer Res 2002;8:3480-3486
    • (2002) Clin Cancer Res , vol.8 , pp. 3480-3486
    • Inoshima, N.1    Nakanishi, Y.2    Minami, T.3
  • 159
    • 14844286511 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression in pN2 on-small cell lung cancer: Lack of prognostic value
    • Tomita M, Matsuzaki Y, Shimizu T, et al. Vascular endothelial growth factor expression in pN2 on-small cell lung cancer: lack of prognostic value. Respirology 2005;10:31-35
    • (2005) Respirology , vol.10 , pp. 31-35
    • Tomita, M.1    Matsuzaki, Y.2    Shimizu, T.3
  • 160
    • 0038010147 scopus 로고    scopus 로고
    • Expression of VEGF, semaphorin SEMA3F, and their common receptors neuropilins NP1 and NP2 in preinvasive bronchial lesions, lung tumours, and cell lines
    • Lantuejoul S, Constantin B, Drabkin H, et al. Expression of VEGF, semaphorin SEMA3F, and their common receptors neuropilins NP1 and NP2 in preinvasive bronchial lesions, lung tumours, and cell lines. J Pathol 2003;200:336-347
    • (2003) J Pathol , vol.200 , pp. 336-347
    • Lantuejoul, S.1    Constantin, B.2    Drabkin, H.3
  • 161
    • 67649971550 scopus 로고    scopus 로고
    • Connective Tissue-Activating Peptide III (CTAP III): A novel blood biomarker for early lung cancer detection
    • Yee J, Sadar M, Sin Don D, et al. Connective Tissue-Activating Peptide III (CTAP III): a novel blood biomarker for early lung cancer detection. J Clin Oncol 2009;17:2787-2792
    • (2009) J Clin Oncol , vol.17 , pp. 2787-2792
    • Yee, J.1    Sadar, M.2    Sin Don, D.3
  • 162
    • 0037314662 scopus 로고    scopus 로고
    • Up-regulation of tumour interleukin-8 expression by infiltrating macrophages: Its correlation with tumour angiogenesis and patient survival in non-small cell lung cancer
    • Chen JJ, Yao PL, Yuan A, et al. Up-regulation of tumour interleukin-8 expression by infiltrating macrophages: its correlation with tumour angiogenesis and patient survival in non-small cell lung cancer. Clin Cancer Res 2003;9:729-737
    • (2003) Clin Cancer Res , vol.9 , pp. 729-737
    • Chen, J.J.1    Yao, P.L.2    Yuan, A.3
  • 163
    • 17744406409 scopus 로고    scopus 로고
    • Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer
    • Arenberg DA, Keane MP, DiGiovine B, et al. Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer. J Clin Invest 1998;102:465-472
    • (1998) J Clin Invest , vol.102 , pp. 465-472
    • Arenberg, D.A.1    Keane, M.P.2    Digiovine, B.3
  • 164
    • 0036469157 scopus 로고    scopus 로고
    • Increased expression of b-cateninpredicts better prognosis in nonsmall cell lung carcinomas
    • Hommura F, Furuuchi K, Yamazaki K, et al. Increased expression of b-cateninpredicts better prognosis in nonsmall cell lung carcinomas. Cancer 2002;94:752-758
    • (2002) Cancer , vol.94 , pp. 752-758
    • Hommura, F.1    Furuuchi, K.2    Yamazaki, K.3
  • 165
    • 0036521335 scopus 로고    scopus 로고
    • The significance of E-cadherin and a-, b-, and c-catenin expression in surgically treated non-small cell lung cancers of 3 cm or less in size
    • Lee YC, Wu CT, Chen CS, et al. The significance of E-cadherin and a-, b-, and c-catenin expression in surgically treated non-small cell lung cancers of 3 cm or less in size. J Thorac Cardiovasc Surg 2002;123:502-507
    • (2002) J Thorac Cardiovasc Surg , vol.123 , pp. 502-507
    • Lee, Y.C.1    Wu, C.T.2    Chen, C.S.3
  • 166
    • 77953738985 scopus 로고    scopus 로고
    • Expression of E-cadherin and beta-catenin in human non-small cell lung cancer and the clinical significance
    • Kase S, Sugio K, Yamazaki K, et al. Expression of E-cadherin and beta-catenin in human non-small cell lung cancer and the clinical significance. Clin Cancer Res 2000;64:789-796
    • (2000) Clin Cancer Res , vol.64 , pp. 789-796
    • Kase, S.1    Sugio, K.2    Yamazaki, K.3
  • 167
    • 0042762970 scopus 로고    scopus 로고
    • Prognostic significance of E-cadherin and b-catenin in resected stage i non-small Paci, Rapicetta & Maramotti cell lung cancer
    • Choi YS, Shim YM, Kim SH, et al. Prognostic significance of E-cadherin and b-catenin in resected stage I non-small Paci, Rapicetta & Maramotti cell lung cancer. Eur J Cardio Thorac Surg 2003;24:441-449
    • (2003) Eur J Cardio Thorac Surg , vol.24 , pp. 441-449
    • Choi, Y.S.1    Shim, Y.M.2    Kim, S.H.3
  • 168
    • 0035105335 scopus 로고    scopus 로고
    • E-cadherin expression associated with differentiation and prognosis in patients with non-small cell lung cancer
    • Liu D, Huang CL, Kameyama K, et al. E-cadherin expression associated with differentiation and prognosis in patients with non-small cell lung cancer. Ann Thorac Surg 2001;71:949-955
    • (2001) Ann Thorac Surg , vol.71 , pp. 949-955
    • Liu, D.1    Huang, C.L.2    Kameyama, K.3
  • 169
    • 0033760493 scopus 로고    scopus 로고
    • Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer
    • Passlick B, Sienel W, Seen-Hibler R, et al. Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer. Clin Cancer Res 2000;6:3944-3948
    • (2000) Clin Cancer Res , vol.6 , pp. 3944-3948
    • Passlick, B.1    Sienel, W.2    Seen-Hibler, R.3
  • 170
    • 5144220875 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumour cells, is a significant prognostic factor in non-small-cell lung cancer
    • Ishikawa S, Takenaka K, Yanagihara K, et al. Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumour cells, is a significant prognostic factor in non-small-cell lung cancer. Clin Cancer Res 2004;10:6579-6585
    • (2004) Clin Cancer Res , vol.10 , pp. 6579-6585
    • Ishikawa, S.1    Takenaka, K.2    Yanagihara, K.3
  • 171
    • 69249154583 scopus 로고    scopus 로고
    • Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer
    • Takano A, Ishikawa N, Nishino R, et al. Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer. Cancer Res 2009;69:6694-6703
    • (2009) Cancer Res , vol.69 , pp. 6694-6703
    • Takano, A.1    Ishikawa, N.2    Nishino, R.3
  • 172
    • 11144356221 scopus 로고    scopus 로고
    • Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours
    • Lantuejoul S, Soria JC, Moro-Sibilot D, et al. Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours. Br J Cancer 2004;90:1222-1229
    • (2004) Br J Cancer , vol.90 , pp. 1222-1229
    • Lantuejoul, S.1    Soria, J.C.2    Moro-Sibilot, D.3
  • 173
    • 34147220127 scopus 로고    scopus 로고
    • Serum amyloid A protein: A potential biomarker correlated with clinical stage of lung cancer
    • Liu DH, Wang XM, Zhang LJ, et al. Serum amyloid A protein: a potential biomarker correlated with clinical stage of lung cancer. Biomed Environ Sci 2007;20:33-40
    • (2007) Biomed Environ Sci , vol.20 , pp. 33-40
    • Liu, D.H.1    Wang, X.M.2    Zhang, L.J.3
  • 174
    • 0035866794 scopus 로고    scopus 로고
    • Overexpression of dihydrodiol dehydrogenase as a prognostic marker of non-small cell lung cancer
    • Hsu NY, Ho HC, Chow KC, et al. Overexpression of dihydrodiol dehydrogenase as a prognostic marker of non-small cell lung cancer. Cancer Res 2001;61:2727-2731
    • (2001) Cancer Res , vol.61 , pp. 2727-2731
    • Hsu, N.Y.1    Ho, H.C.2    Chow, K.C.3
  • 175
    • 37049026705 scopus 로고    scopus 로고
    • Identification of putative serum glycoprotein biomarkers for human lung adenocarcinoma by multilectin affinity chromatography, and LC-MS/MS
    • Heo SH, Lee SJ, Ryoo HM, et al. Identification of putative serum glycoprotein biomarkers for human lung adenocarcinoma by multilectin affinity chromatography, and LC-MS/MS. Proteomics 2007;7:4292-4302
    • (2007) Proteomics , vol.7 , pp. 4292-4302
    • Heo, S.H.1    Lee, S.J.2    Ryoo, H.M.3
  • 176
    • 70350323631 scopus 로고    scopus 로고
    • Diagnosis value of serum B7-H3 expression in non-small cell lung cancer
    • Zhang G, Xu Y, Lu X, et al. Diagnosis value of serum B7-H3 expression in non-small cell lung cancer. Lung Cancer 2009;66:245-249
    • (2009) Lung Cancer , vol.66 , pp. 245-249
    • Zhang, G.1    Xu, Y.2    Lu, X.3
  • 177
    • 0023637473 scopus 로고
    • Immunohistochemical markers of small cell carcinoma and related neuroendocrine tumours of the lung
    • Addis BJ, Hamid Q, Ibrahim NB, et al. Immunohistochemical markers of small cell carcinoma and related neuroendocrine tumours of the lung. J Pathol 1987;153:137-150
    • (1987) J Pathol , vol.153 , pp. 137-150
    • Addis, B.J.1    Hamid, Q.2    Ibrahim, N.B.3
  • 178
    • 0035503380 scopus 로고    scopus 로고
    • Proteomics-based identification of protein gene product 9.5 as a tumour antigen that induces a humoral immune response in lung cancer
    • Brichory F, Beer D, Le Naour F, et al. Proteomics-based identification of protein gene product 9.5 as a tumour antigen that induces a humoral immune response in lung cancer. Cancer Res 2001;61:7908-7912
    • (2001) Cancer Res , vol.61 , pp. 7908-7912
    • Brichory, F.1    Beer, D.2    Le Naour, F.3
  • 179
    • 3042816190 scopus 로고    scopus 로고
    • Hypoxia-indicible factor-1a in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways
    • Swinson DEB, Jones JL, Cox G, et al. Hypoxia-indicible factor-1a in non small cell lung cancer: relation to growth factor, protease and apoptosis pathways. Int J Cancer 2004;111:43-50
    • (2004) Int J Cancer , vol.111 , pp. 43-50
    • Deb, S.1    Jones, J.L.2    Cox, G.3
  • 180
    • 4644304354 scopus 로고    scopus 로고
    • Loss of FHIT protein expression is related to high proliferation, low apoptosis and worse prognosis in non-small cell lung cancer
    • Toledo G, Sola JJ, Lozano MD, et al. Loss of FHIT protein expression is related to high proliferation, low apoptosis and worse prognosis in non-small cell lung cancer. Mod Pathol 2004;17:440-448
    • (2004) Mod Pathol , vol.17 , pp. 440-448
    • Toledo, G.1    Sola, J.J.2    Lozano, M.D.3
  • 181
    • 23044494636 scopus 로고    scopus 로고
    • Differential proteomic serum pattern of low molecular weight proteins expressed by adenocarcinoma lung cancer patients
    • Maciel CM, Junqueira M, Paschoal ME, et al. Differential proteomic serum pattern of low molecular weight proteins expressed by adenocarcinoma lung cancer patients. J Exp Ther Oncol 2005;5:31-38
    • (2005) J Exp Ther Oncol , vol.5 , pp. 31-38
    • MacIel, C.M.1    Junqueira, M.2    Paschoal, M.E.3
  • 182
    • 0037649051 scopus 로고    scopus 로고
    • HnRNP B1 expression in benign and malignant lung disease
    • Snead DR, Perunovic B, Cullen N, et al. hnRNP B1 expression in benign and malignant lung disease. J Pathol 2003;200:88-94
    • (2003) J Pathol , vol.200 , pp. 88-94
    • Snead, D.R.1    Perunovic, B.2    Cullen, N.3
  • 183
    • 34547137152 scopus 로고    scopus 로고
    • Cancer immunomics: Using autoantibody signatures for biomarker discovery
    • Caron M, Choquet-Kastylevsky G, Joubert-Caron R. Cancer immunomics: using autoantibody signatures for biomarker discovery. Mol Cell Proteomics 2007;6:1115-1122
    • (2007) Mol Cell Proteomics , vol.6 , pp. 1115-1122
    • Caron, M.1    Choquet-Kastylevsky, G.2    Joubert-Caron, R.3
  • 184
    • 23944522808 scopus 로고    scopus 로고
    • The sentinel within: Exploiting the immune system for cancer biomarkers
    • Anderson KS, LaBaer J. The sentinel within: exploiting the immune system for cancer biomarkers. J Proteome Res 2005;4:1123-1133
    • (2005) J Proteome Res , vol.4 , pp. 1123-1133
    • Anderson, K.S.1    Labaer, J.2
  • 185
    • 0037227993 scopus 로고    scopus 로고
    • Harnessing immunity for cancer marker discovery
    • Hanash S. Harnessing immunity for cancer marker discovery. Nat Biotechnol 2003;21:37-38
    • (2003) Nat Biotechnol , vol.21 , pp. 37-38
    • Hanash, S.1
  • 186
    • 0034113998 scopus 로고    scopus 로고
    • P53 antibodies in the sera of patients with various types of cancer: A review
    • Soussi T. P53 antibodies in the sera of patients with various types of cancer: a review. Cancer Res 2000;60:1777-1788
    • (2000) Cancer Res , vol.60 , pp. 1777-1788
    • Soussi, T.1
  • 187
    • 41149178259 scopus 로고    scopus 로고
    • Autoantibodies to tumour-associated antigens: Reporters from the immune system
    • Tan EM, Zhang J. Autoantibodies to tumour-associated antigens: reporters from the immune system. Immunol Rev 2008;222:328-340
    • (2008) Immunol Rev , vol.222 , pp. 328-340
    • Tan, E.M.1    Zhang, J.2
  • 188
    • 33750315127 scopus 로고    scopus 로고
    • Profiling tumour-associated antibodies for early detection of non-small cell lung cancer
    • Zhong L, Coe SP, Stromberg AJ, et al. Profiling tumour-associated antibodies for early detection of non-small cell lung cancer. J Thorac Oncol 2006;1:513-519
    • (2006) J Thorac Oncol , vol.1 , pp. 513-519
    • Zhong, L.1    Coe, S.P.2    Stromberg, A.J.3
  • 189
    • 37549061448 scopus 로고    scopus 로고
    • Identification of 14-3-3 theta as an antigen that induces a humoral response in lung cancer
    • Pereira-Faca SR, Kuick R, Puravs E, et al. Identification of 14-3-3 theta as an antigen that induces a humoral response in lung cancer. Cancer Res 2007;67:12000-12006
    • (2007) Cancer Res , vol.67 , pp. 12000-12006
    • Pereira-Faca, S.R.1    Kuick, R.2    Puravs, E.3
  • 190
    • 40649124272 scopus 로고    scopus 로고
    • Autoantibodies in lung cancer: Possibilities for early detection and subsequent cure
    • Chapman CJ, Murray A, McElveen JE, et al. Autoantibodies in lung cancer: possibilities for early detection and subsequent cure. Thorax 2008;63:228-233
    • (2008) Thorax , vol.63 , pp. 228-233
    • Chapman, C.J.1    Murray, A.2    McElveen, J.E.3
  • 191
    • 33646098665 scopus 로고    scopus 로고
    • Humoral immune responses of lung cancer patients against tumour antigen NY-ESO-1
    • Tureci O, Mack U, Luxemburger U, et al. Humoral immune responses of lung cancer patients against tumour antigen NY-ESO-1. Cancer Lett 2006;236:64-71
    • (2006) Cancer Lett , vol.236 , pp. 64-71
    • Tureci, O.1    MacK, U.2    Luxemburger, U.3
  • 192
    • 35348931537 scopus 로고    scopus 로고
    • Targeting the neural cell adhesion molecule in cancer
    • Jensen M, Berthold F. Targeting the neural cell adhesion molecule in cancer. Cancer Lett 2007;258:9-21
    • (2007) Cancer Lett , vol.258 , pp. 9-21
    • Jensen, M.1    Berthold, F.2
  • 193
  • 194
    • 11344272281 scopus 로고    scopus 로고
    • The promise of metabolomics in cancer molecular therapeutics
    • Fan TW, Lane AN, Higashi RM. The promise of metabolomics in cancer molecular therapeutics. Curr Opin Mol Ther 2004;6:584-592
    • (2004) Curr Opin Mol Ther , vol.6 , pp. 584-592
    • Fan, T.W.1    Lane, A.N.2    Higashi, R.M.3
  • 195
    • 30844471152 scopus 로고    scopus 로고
    • Characterization of the biochemical effects of 1 nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition
    • Azmi J, Connelly J, Holmes E, et al. Characterization of the biochemical effects of 1 nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition. Biomarkers 2005;10:401-416
    • (2005) Biomarkers , vol.10 , pp. 401-416
    • Azmi, J.1    Connelly, J.2    Holmes, E.3
  • 196
    • 68549085318 scopus 로고    scopus 로고
    • Altered regulation of metabolic pathways in human lung cancer discerned by (13) C stable isotope-resolved metabolomics (SIRM)
    • Fan TW, Lane AN, Higashi RM, et al. Altered regulation of metabolic pathways in human lung cancer discerned by (13) C stable isotope-resolved metabolomics (SIRM). Mol Cancer 2009;8:41
    • (2009) Mol Cancer , vol.8 , pp. 41
    • Fan, T.W.1    Lane, A.N.2    Higashi, R.M.3
  • 197
    • 2942737264 scopus 로고    scopus 로고
    • Tumour-specific methylation in bronchial lavage for the early detection of non-small-cell lung cancer
    • Kim H, Kwon YM, Kim JS, et al. Tumour-specific methylation in bronchial lavage for the early detection of non-small-cell lung cancer. J Clin Oncol 2004;22:2363-2370
    • (2004) J Clin Oncol , vol.22 , pp. 2363-2370
    • Kim, H.1    Kwon, Y.M.2    Kim, J.S.3
  • 198
    • 4143132121 scopus 로고    scopus 로고
    • Promoter hypermethylation of resected bronchial margins: A field defect of changes?
    • Guo M, House MG, Hooker C, et al. Promoter hypermethylation of resected bronchial margins: a field defect of changes? Clin Cancer Res 2004;10:5131-5136
    • (2004) Clin Cancer Res , vol.10 , pp. 5131-5136
    • Guo, M.1    House, M.G.2    Hooker, C.3
  • 199
    • 26444431818 scopus 로고    scopus 로고
    • Promoter methylation of genes in bronchial lavages: A marker for early diagnosis of primary and relapsing non-small cell lung cancer?
    • De Fraipont F, Moro-Sibilot D, Michelland S, et al. Promoter methylation of genes in bronchial lavages: a marker for early diagnosis of primary and relapsing non-small cell lung cancer? Lung Cancer 2005;50:199-209
    • (2005) Lung Cancer , vol.50 , pp. 199-209
    • De Fraipont, F.1    Moro-Sibilot, D.2    Michelland, S.3
  • 200
    • 33645967485 scopus 로고    scopus 로고
    • Methylation of RAS association domain family protein 1A as a biomarker of lung cancer
    • Grote HJ, Schmiemann V, Geddert H, et al. Methylation of RAS association domain family protein 1A as a biomarker of lung cancer. Cancer 2006;108:129-134
    • (2006) Cancer , vol.108 , pp. 129-134
    • Grote, H.J.1    Schmiemann, V.2    Geddert, H.3
  • 201
    • 27744434546 scopus 로고    scopus 로고
    • Methylation assay for the diagnosis of lung cancer on bronchial aspirates: A cohort study
    • Schmiemann V, Bocking A, Kazimirek M, et al. Methylation assay for the diagnosis of lung cancer on bronchial aspirates: a cohort study. Clin Cancer Res 2005;11:7728-7734
    • (2005) Clin Cancer Res , vol.11 , pp. 7728-7734
    • Schmiemann, V.1    Bocking, A.2    Kazimirek, M.3
  • 202
    • 0035866349 scopus 로고    scopus 로고
    • Cancer-specific genomic instability in bronchial lavage: A molecular tool for lung cancer detection
    • Liloglou T, Maloney P, Xinarianos G, et al. Cancer-specific genomic instability in bronchial lavage: a molecular tool for lung cancer detection. Cancer Res 2001;61:1624-1628
    • (2001) Cancer Res , vol.61 , pp. 1624-1628
    • Liloglou, T.1    Maloney, P.2    Xinarianos, G.3
  • 203
    • 15244351454 scopus 로고    scopus 로고
    • Quantification of free RNA in serum and bronchial lavage: A new diagnostic tool in lung cancer detection?
    • Schmidt B, Engel E, Carstensen T, et al. Quantification of free RNA in serum and bronchial lavage: a new diagnostic tool in lung cancer detection? Lung Cancer 2005;48:145-147
    • (2005) Lung Cancer , vol.48 , pp. 145-147
    • Schmidt, B.1    Engel, E.2    Carstensen, T.3
  • 204
    • 0034326238 scopus 로고    scopus 로고
    • Predicting lung cancer by detecting aberrant promoter methylation in sputum
    • Palmisano WA, Divine KK, Saccomanno G, et al. Predicting lung cancer by detecting aberrant promoter methylation in sputum. Cancer Res 2000;60:5954-5958
    • (2000) Cancer Res , vol.60 , pp. 5954-5958
    • Palmisano, W.A.1    Divine, K.K.2    Saccomanno, G.3
  • 205
    • 33846869304 scopus 로고    scopus 로고
    • Genetic deletions in sputum as diagnostic markers for early detection of stage i non-small cell lung cancer
    • Li R, Todd NW, Qiu Q, et al. Genetic deletions in sputum as diagnostic markers for early detection of stage I non-small cell lung cancer. Clin Cancer Res 2007;13:482-487
    • (2007) Clin Cancer Res , vol.13 , pp. 482-487
    • Li, R.1    Todd, N.W.2    Qiu, Q.3
  • 206
    • 25144439378 scopus 로고    scopus 로고
    • Assessing abnormal gene promoter methylation in paraffin-embedded sputum from patients with NSCLC
    • Olaussen KA, Soria JC, Park YW, et al. Assessing abnormal gene promoter methylation in paraffin-embedded sputum from patients with NSCLC. Eur J Cancer 2005;41:2112-2119
    • (2005) Eur J Cancer , vol.41 , pp. 2112-2119
    • Olaussen, K.A.1    Soria, J.C.2    Park, Y.W.3
  • 207
    • 0037096424 scopus 로고    scopus 로고
    • Increase of sensitivity of sputum cytology using high-resolution image cytometry: Field study results
    • Palcic B, Garner DM, Beveridge J, et al. Increase of sensitivity of sputum cytology using high-resolution image cytometry: field study results. Cytometry 2002;50:168-176
    • (2002) Cytometry , vol.50 , pp. 168-176
    • Palcic, B.1    Garner, D.M.2    Beveridge, J.3
  • 208
    • 33751322125 scopus 로고    scopus 로고
    • Copy number gains on 5p15, 6p11-q11, 7p12, and 8q24 are rare in sputum cells of individuals at high risk of lung cancer
    • Kettunen E, Salmenkivi K, Vuopala K, et al. Copy number gains on 5p15, 6p11-q11, 7p12, and 8q24 are rare in sputum cells of individuals at high risk of lung cancer. Lung Cancer 2006;54:169-176
    • (2006) Lung Cancer , vol.54 , pp. 169-176
    • Kettunen, E.1    Salmenkivi, K.2    Vuopala, K.3
  • 209
    • 37349048532 scopus 로고    scopus 로고
    • Proteomics as a method for early detection of cancer: A review of proteomics, exhaled breath condensate, and lung cancer screening
    • Conrad DH, Goyette J, Thomas PS. Proteomics as a method for early detection of cancer: a review of proteomics, exhaled breath condensate, and lung cancer screening. J Gen Intern Med 2008;23:78-84
    • (2008) J Gen Intern Med , vol.23 , pp. 78-84
    • Conrad, D.H.1    Goyette, J.2    Thomas, P.S.3
  • 210
    • 0036968928 scopus 로고    scopus 로고
    • Exhaled breath condensate: An evolving tool for noninvasive evaluation of lung disease
    • Hunt J. Exhaled breath condensate: an evolving tool for noninvasive evaluation of lung disease. J Allergy Clin Immunol 2002;110:28-34
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 28-34
    • Hunt, J.1
  • 211
    • 3042582133 scopus 로고    scopus 로고
    • Endothelin-1 is increased in the breath condensate of patients with non-small-cell lung cancer
    • Carpagnano GE, Foschino-Barbaro MP, Resta O, et al. Endothelin-1 is increased in the breath condensate of patients with non-small-cell lung cancer. Oncology 2004;66:180-184
    • (2004) Oncology , vol.66 , pp. 180-184
    • Carpagnano, G.E.1    Foschino-Barbaro, M.P.2    Resta, O.3
  • 212
    • 24944519230 scopus 로고    scopus 로고
    • 3p microsatellite alterations in exhaled breath condensate from patients with non-small cell lung cancer
    • Carpagnano GE, Foschino-Barbaro MP, Mule G, et al. 3p microsatellite alterations in exhaled breath condensate from patients with non-small cell lung cancer. Am J Respir Crit Care Med 2005;172:738-744
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 738-744
    • Carpagnano, G.E.1    Foschino-Barbaro, M.P.2    Mule, G.3
  • 213
    • 67349256184 scopus 로고    scopus 로고
    • Prognostic value of exhaled microsatellite alterations at 3p in NSCLC patients
    • Carpagnano GE, Spanevello A, Carpagnano F, et al. Prognostic value of exhaled microsatellite alterations at 3p in NSCLC patients. Lung Cancer 2009;64(3):334-340
    • (2009) Lung Cancer , vol.64 , Issue.3 , pp. 334-340
    • Carpagnano, G.E.1    Spanevello, A.2    Carpagnano, F.3
  • 214
    • 34548687010 scopus 로고    scopus 로고
    • IL-2, TNF-alpha, and leptin: Local versus systemic concentrations in NSCLC patients
    • Carpagnano GE, Spanevello A, Curci C, et al. IL-2, TNF-alpha, and leptin: local versus systemic concentrations in NSCLC patients. Oncol Res 2007;16(8):375-381
    • (2007) Oncol Res , vol.16 , Issue.8 , pp. 375-381
    • Carpagnano, G.E.1    Spanevello, A.2    Curci, C.3
  • 215
    • 0022191230 scopus 로고
    • Volatile organic compounds in exhaled air from patients with lung cancer
    • Gordon SM, Szidon JP, Krotoszynski BK, et al. Volatile organic compounds in exhaled air from patients with lung cancer. Clin Chem 1985;31:1278-1282
    • (1985) Clin Chem , vol.31 , pp. 1278-1282
    • Gordon, S.M.1    Szidon, J.P.2    Krotoszynski, B.K.3
  • 216
    • 34447298617 scopus 로고    scopus 로고
    • Diagnosis of lung cancer by the analysis of exhaled breath with a colorimetric sensor array
    • Mazzone PJ, Hammel J, Dweik R, et al. Diagnosis of lung cancer by the analysis of exhaled breath with a colorimetric sensor array. Thorax 2007;62:565-568
    • (2007) Thorax , vol.62 , pp. 565-568
    • Mazzone, P.J.1    Hammel, J.2    Dweik, R.3
  • 217
    • 2942754069 scopus 로고    scopus 로고
    • Increased keratin content detected by protomi analysis of exhaled breath condensate from healthy persons who smoke
    • Gianazza E, Allegra L, Bucchioni E, et al. Increased keratin content detected by protomi analysis of exhaled breath condensate from healthy persons who smoke. Am J Med 2004;117(1):51-54
    • (2004) Am J Med , vol.117 , Issue.1 , pp. 51-54
    • Gianazza, E.1    Allegra, L.2    Bucchioni, E.3
  • 218
    • 61449150588 scopus 로고    scopus 로고
    • Circulating plasma DNA as diagnostic biomarker in non-small cell lung cancer
    • Paci M, Maramotti S, Bellesia E, et al. Circulating plasma DNA as diagnostic biomarker in non-small cell lung cancer. Lung Cancer 2009;64:92-97
    • (2009) Lung Cancer , vol.64 , pp. 92-97
    • Paci, M.1    Maramotti, S.2    Bellesia, E.3
  • 219
    • 33749573647 scopus 로고    scopus 로고
    • Circulating DNA and lung cancer
    • Xue X, Zhu YM, Woll PJ. Circulating DNA and lung cancer. Ann NY Acad Sci 2006;1075:154-164
    • (2006) Ann NY Acad Sci , vol.1075 , pp. 154-164
    • Xue, X.1    Zhu, Y.M.2    Woll, P.J.3
  • 220
    • 0642311916 scopus 로고    scopus 로고
    • Quantification of free circulating DNA as a diagnostic marker in lung cancer
    • Sozzi G, Conte D, Leon M, et al. Quantification of free circulating DNA as a diagnostic marker in lung cancer. J Clin Oncol 2003;21:3902-3908
    • (2003) J Clin Oncol , vol.21 , pp. 3902-3908
    • Sozzi, G.1    Conte, D.2    Leon, M.3
  • 221
    • 33748046788 scopus 로고    scopus 로고
    • Quantitative detection of p53 mutations in plasma DNA from tobacco smokers
    • Hagiwara N, Mechanic LE, Trivers GE, et al. Quantitative detection of p53 mutations in plasma DNA from tobacco smokers. Cancer Res 2006;66:8309-8317
    • (2006) Cancer Res , vol.66 , pp. 8309-8317
    • Hagiwara, N.1    Mechanic, L.E.2    Trivers, G.E.3
  • 222
    • 0032696782 scopus 로고    scopus 로고
    • Detection of microsatellite alterations in plasma DNA of non-small cell lung cancer patients: A prospect for early diagnosis
    • Sozzi G, Musso K, Ratcliffe C, et al. Detection of microsatellite alterations in plasma DNA of non-small cell lung cancer patients: a prospect for early diagnosis. Clin Cancer Res 1999;5:2689-2692
    • (1999) Clin Cancer Res , vol.5 , pp. 2689-2692
    • Sozzi, G.1    Musso, K.2    Ratcliffe, C.3
  • 223
    • 35648953334 scopus 로고    scopus 로고
    • Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma
    • Hsu HS, Chen TP, Hung CH, et al. Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma. Cancer 2007;110:2019-2026
    • (2007) Cancer , vol.110 , pp. 2019-2026
    • Hsu, H.S.1    Chen, T.P.2    Hung, C.H.3
  • 224
    • 34247217491 scopus 로고    scopus 로고
    • Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum
    • Belinsky SA, Grimes MJ, Casas E, et al. Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum. Br J Cancer 2007;96:1278-1283
    • (2007) Br J Cancer , vol.96 , pp. 1278-1283
    • Belinsky, S.A.1    Grimes, M.J.2    Casas, E.3
  • 225
    • 0034750642 scopus 로고    scopus 로고
    • Circulating RNA as tumour marker: Detection of 5T4 mRNA in breast and lung cancer patient serum
    • Kopreski MS, Benko FA, Gocke CD. Circulating RNA as tumour marker: detection of 5T4 mRNA in breast and lung cancer patient serum. Ann NY Acad Sci 2001;945:172-178
    • (2001) Ann NY Acad Sci , vol.945 , pp. 172-178
    • Kopreski, M.S.1    Benko, F.A.2    Gocke, C.D.3
  • 226
    • 67650520139 scopus 로고    scopus 로고
    • Detection of cancer with serum miRNAs on an oligonucleotide microarray
    • Lodes MJ, Caraballo M, Suciu D, et al. Detection of cancer with serum miRNAs on an oligonucleotide microarray. PLoS One 2009;4(7):e6229
    • (2009) PLoS One , vol.4 , Issue.7
    • Lodes, M.J.1    Caraballo, M.2    Suciu, D.3
  • 227
    • 53349177819 scopus 로고    scopus 로고
    • Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases
    • Chen X, Ba Y, Ma L, et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 2008;18:997-1006
    • (2008) Cell Res , vol.18 , pp. 997-1006
    • Chen, X.1    Ba, Y.2    Ma, L.3
  • 228
    • 0035845531 scopus 로고    scopus 로고
    • Chemosensivity prediction by transcriptional profiling
    • Staunton JE, Slonim DK, Coller HA, et al. Chemosensivity prediction by transcriptional profiling. Proc Natl Acad Sci USA 2001;98:10787-10792
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10787-10792
    • Staunton, J.E.1    Slonim, D.K.2    Coller, H.A.3
  • 229
    • 33750727368 scopus 로고    scopus 로고
    • Genomic signatures to guide the use of chemotherapeutics
    • Potti A, Dressman HK, Bild A, et al. Genomic signatures to guide the use of chemotherapeutics. Nat Med 2006;12:1294-1300
    • (2006) Nat Med , vol.12 , pp. 1294-1300
    • Potti, A.1    Dressman, H.K.2    Bild, A.3
  • 230
    • 35348860753 scopus 로고    scopus 로고
    • Pharmacogenomics strategies provide rational approach to the treatment of cisplatin-resistant patients with advanced cancer
    • Hsu DS, Balakumaran BS, Acharya CR, et al. Pharmacogenomics strategies provide rational approach to the treatment of cisplatin-resistant patients with advanced cancer. J Clin Oncol 2007;25:4350-4357
    • (2007) J Clin Oncol , vol.25 , pp. 4350-4357
    • Hsu, D.S.1    Balakumaran, B.S.2    Acharya, C.R.3
  • 231
    • 33747028745 scopus 로고    scopus 로고
    • Anticancer drug clustering in lung cancer based on gene expression profiles and sensitivity database
    • Gemma A, Li C, Sugiyama Y, et al. Anticancer drug clustering in lung cancer based on gene expression profiles and sensitivity database. BMC Cancer 2006;6:174
    • (2006) BMC Cancer , vol.6 , pp. 174
    • Gemma, A.1    Li, C.2    Sugiyama, Y.3
  • 232
    • 70349376330 scopus 로고    scopus 로고
    • Molecular predictive and prognostic markers in non-small-cell lung cancer
    • Coate LE, John T, Tsao MS, et al. Molecular predictive and prognostic markers in non-small-cell lung cancer. Lancet Oncol 2009;10:1001-1010
    • (2009) Lancet Oncol , vol.10 , pp. 1001-1010
    • Coate, L.E.1    John, T.2    Tsao, M.S.3
  • 233
    • 60849109966 scopus 로고    scopus 로고
    • Standard operating procedures for serum and plasma collection: Early detection research network consensus statement standard operating procedure integration working group
    • Tuck MK, Chan DW, Chia D, et al. Standard operating procedures for serum and plasma collection: early detection research network consensus statement standard operating procedure integration working group. J Proteome Res 2009;8:113-117
    • (2009) J Proteome Res , vol.8 , pp. 113-117
    • Tuck, M.K.1    Chan, D.W.2    Chia, D.3
  • 234
    • 0038012549 scopus 로고    scopus 로고
    • Biological sample collection and processing for molecular epidemiological studies
    • Holland NT, Smith MT, Eskenazi B, et al. Biological sample collection and processing for molecular epidemiological studies. Mutat Res 2003;543:217-234
    • (2003) Mutat Res , vol.543 , pp. 217-234
    • Holland, N.T.1    Smith, M.T.2    Eskenazi, B.3
  • 236
    • 77953788200 scopus 로고    scopus 로고
    • (National Cancer Institute, Division of Cancer Prevention) Available from:
    • Early Detection Research Network (National Cancer Institute, Division of Cancer Prevention). Available from: http://www.cancer.gov/edrn
    • Early Detection Research Network
  • 237
    • 0035908491 scopus 로고    scopus 로고
    • Phases of biomarker development for early detection of cancer
    • Sullivan Pepe M, Etzioni R, Feng Z, et al. Phases of biomarker development for early detection of cancer. J Natl Cancer Inst 2001;93:1054-1061
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1054-1061
    • Sullivan Pepe, M.1    Etzioni, R.2    Feng, Z.3
  • 238
    • 23644432019 scopus 로고    scopus 로고
    • Statistics subcommittee of the NCI-EORT working group on cancer diagnostics
    • McShane LM, Altman DG, Sauerbrei W, et al. Statistics subcommittee of the NCI-EORT working group on cancer diagnostics. Eur J Cancer 2005;41(12):1690- 1696
    • (2005) Eur J Cancer , vol.41 , Issue.12 , pp. 1690-1696
    • McShane, L.M.1    Altman, D.G.2    Sauerbrei, W.3
  • 239
    • 0034750609 scopus 로고    scopus 로고
    • Detection of amplifiable messenger RNA in the serum of patients with lung cancer
    • Fleischhacker M, Beinert T, Ermitsch M, et al. Detection of amplifiable messenger RNA in the serum of patients with lung cancer. Ann NY Acad Sci 2001;945:179-188
    • (2001) Ann NY Acad Sci , vol.945 , pp. 179-188
    • Fleischhacker, M.1    Beinert, T.2    Ermitsch, M.3
  • 240
    • 15044356588 scopus 로고    scopus 로고
    • Detection of plasma hnRNP B1 mRNA, a new cancer biomarker, in lung cancer patients by quantitative real-time polymerase chain reaction
    • Sueoka E, Sueoka N, Iwanaga K, et al. Detection of plasma hnRNP B1 mRNA, a new cancer biomarker, in lung cancer patients by quantitative real-time polymerase chain reaction. Lung Cancer 2005;48(1):77-83
    • (2005) Lung Cancer , vol.48 , Issue.1 , pp. 77-83
    • Sueoka, E.1    Sueoka, N.2    Iwanaga, K.3
  • 241
    • 0036898622 scopus 로고    scopus 로고
    • P16(INK4A) hypermethylation detected by fluorescent methylation-specific PCR in plasmas from non-small cell lung cancer
    • Bearzatto A, Conte D, Frattini M, et al. p16(INK4A) hypermethylation detected by fluorescent methylation-specific PCR in plasmas from non-small cell lung cancer. Clin Cancer Res 2002;8(12):3782-3787
    • (2002) Clin Cancer Res , vol.8 , Issue.12 , pp. 3782-3787
    • Bearzatto, A.1    Conte, D.2    Frattini, M.3
  • 242
    • 0037114362 scopus 로고    scopus 로고
    • Detection of p16 hypermethylation in circulating plasma DNA of non-small-cell lung cancer patients
    • An Q, Liu Y, Gao Y, et al. Detection of p16 hypermethylation in circulating plasma DNA of non-small-cell lung cancer patients. Cancer Lett 2002;188:109-114
    • (2002) Cancer Lett , vol.188 , pp. 109-114
    • An, Q.1    Liu, Y.2    Gao, Y.3
  • 243
    • 0346888541 scopus 로고    scopus 로고
    • Hypermethylation of p16INK4alpha in Chinese lung cancer patients: Biological and clinical implications
    • Liu Y, An Q, Li L, et al. Hypermethylation of p16INK4alpha in Chinese lung cancer patients: biological and clinical implications. Carcinogenesis 2003;24:1897-1901
    • (2003) Carcinogenesis , vol.24 , pp. 1897-1901
    • Liu, Y.1    An, Q.2    Li, L.3
  • 244
    • 0033788509 scopus 로고    scopus 로고
    • Microsatellite alterations and TP53 mutations in plasma DNA of small-cell lung cancer patients: Follow-up study and prognostic significance
    • Gonzalez R, Silva JM, Sanchez A, et al. Microsatellite alterations and TP53 mutations in plasma DNA of small-cell lung cancer patients: follow-up study and prognostic significance. Ann Oncol 2000;11:1097-1104
    • (2000) Ann Oncol , vol.11 , pp. 1097-1104
    • Gonzalez, R.1    Silva, J.M.2    Sanchez, A.3
  • 245
    • 0345687975 scopus 로고    scopus 로고
    • Detecting lung cancer in plasma with the use of multiple genetic markers
    • Andriani F, Conte D, Mastrangelo T, et al. Detecting lung cancer in plasma with the use of multiple genetic markers. Int J Cancer 2004;108(1):91-96
    • (2004) Int J Cancer , vol.108 , Issue.1 , pp. 91-96
    • Andriani, F.1    Conte, D.2    Mastrangelo, T.3
  • 246
    • 77953764319 scopus 로고    scopus 로고
    • Methylation patterns and K-ras mutations in tumour and paired serum of resected non-small-cell lung cancer patients
    • Ramirez JL, Sarries C, de Castro PL, et al. Methylation patterns and K-ras mutations in tumour and paired serum of resected non-small-cell lung cancer patients. Cancer Lett 2003;11:1219-1225
    • (2003) Cancer Lett , vol.11 , pp. 1219-1225
    • Ramirez, J.L.1    Sarries, C.2    De Castro, P.L.3
  • 247
    • 0037081085 scopus 로고    scopus 로고
    • Quantitative adenomatous polyposis coli promoter methylation analysis in tumour tissue, serum and plasma DNA of patients with lung cancer
    • Usadel H, Brabender J, Danenberg KD, et al. Quantitative adenomatous polyposis coli promoter methylation analysis in tumour tissue, serum and plasma DNA of patients with lung cancer. Cancer Res 2002;62:371-375
    • (2002) Cancer Res , vol.62 , pp. 371-375
    • Usadel, H.1    Brabender, J.2    Danenberg, K.D.3
  • 248
    • 0034528340 scopus 로고    scopus 로고
    • Detection of microsatellite instability and loss of heterozygosity in serum DNA of small and non-small cell lung cancer patients: A tool for early diagnosis?
    • Cuda G, Gallelli A, Nistico A, et al. Detection of microsatellite instability and loss of heterozygosity in serum DNA of small and non-small cell lung cancer patients: a tool for early diagnosis? Lung Cancer 2000;30:211-214
    • (2000) Lung Cancer , vol.30 , pp. 211-214
    • Cuda, G.1    Gallelli, A.2    Nistico, A.3
  • 249
    • 0034102472 scopus 로고    scopus 로고
    • Detection of microsatellite alterations in DNA isolated in from tumour cells and from plasma DNA of patients with lung cancer
    • Bruhn N, Beinert T, Oehm C, et al. Detection of microsatellite alterations in DNA isolated in from tumour cells and from plasma DNA of patients with lung cancer. Ann NY Acad Sci 2000;906:72-82
    • (2000) Ann NY Acad Sci , vol.906 , pp. 72-82
    • Bruhn, N.1    Beinert, T.2    Oehm, C.3
  • 250
    • 2942525078 scopus 로고    scopus 로고
    • Genetic abnormalities in plasma DNA of patients with lung cancer and other respiratory diseases
    • Kahn S, Coulson JM, Woll PJ. Genetic abnormalities in plasma DNA of patients with lung cancer and other respiratory diseases. Int J Cancer 2004;110:891-895
    • (2004) Int J Cancer , vol.110 , pp. 891-895
    • Kahn, S.1    Coulson, J.M.2    Woll, P.J.3
  • 251
    • 0038326550 scopus 로고    scopus 로고
    • Plasma DNA microsatellite panels as sensitive and tumour-specific marker in lung cancer patients
    • Beau-Faller M, Gaub MP, Schneider A, et al. Plasma DNA microsatellite panels as sensitive and tumour-specific marker in lung cancer patients. Int J Cancer 2003;105:361-370
    • (2003) Int J Cancer , vol.105 , pp. 361-370
    • Beau-Faller, M.1    Gaub, M.P.2    Schneider, A.3
  • 252
    • 2442593569 scopus 로고    scopus 로고
    • Improved diagnostic sensitivity for lung cancer using an automated quantitative cytology system and uridine 5¢-triphosphate-induced sputum specimens
    • Johnson FL, Turic B, Kemp R, et al. Improved diagnostic sensitivity for lung cancer using an automated quantitative cytology system and uridine 5¢-triphosphate-induced sputum specimens. Chest 2004;125:157S-8S
    • (2004) Chest , vol.125
    • Johnson, F.L.1    Turic, B.2    Kemp, R.3
  • 253
    • 0031427367 scopus 로고    scopus 로고
    • Prospective detection of preclinical lung cancer: Results from two studies of heterogeneous nuclear ribonucleoprotein A2/B1 overexpression
    • Tockman MS, Mulshine JL, Piantadosi S, et al. Prospective detection of preclinical lung cancer: results from two studies of heterogeneous nuclear ribonucleoprotein A2/B1 overexpression. Clin Cancer Res 1997;3:2237-2246
    • (1997) Clin Cancer Res , vol.3 , pp. 2237-2246
    • Tockman, M.S.1    Mulshine, J.L.2    Piantadosi, S.3
  • 254
    • 0037174792 scopus 로고    scopus 로고
    • A fluorescence in situ hybridization-based assay for improved detection of lung cancer cells in bronchial washing specimens
    • Sokolowa IA, Bubendorf L, O'Hare A, et al. A fluorescence in situ hybridization-based assay for improved detection of lung cancer cells in bronchial washing specimens. Cancer 2002;96:306-315
    • (2002) Cancer , vol.96 , pp. 306-315
    • Sokolowa, I.A.1    Bubendorf, L.2    O'hare, A.3
  • 255
    • 0033396697 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoprotein A2/B1 up-regulation in bronchial lavage specimens: A clinical marker of early lung cancer detection
    • Fielding P, Turnbull L, Prime W, et al. Heterogeneous nuclear ribonucleoprotein A2/B1 up-regulation in bronchial lavage specimens: a clinical marker of early lung cancer detection. Clin Cancer Res 1999;5:4048-4052
    • (1999) Clin Cancer Res , vol.5 , pp. 4048-4052
    • Fielding, P.1    Turnbull, L.2    Prime, W.3
  • 256
    • 1642493715 scopus 로고    scopus 로고
    • Detection of p53 gene mutations in exhaled breath condensate of non-small cell lung cancer patients
    • Gessner C, Kuhn H, Toepfer K, et al. Detection of p53 gene mutations in exhaled breath condensate of non-small cell lung cancer patients. Lung Cancer 2004;43:215-222
    • (2004) Lung Cancer , vol.43 , pp. 215-222
    • Gessner, C.1    Kuhn, H.2    Toepfer, K.3
  • 257
    • 15844372318 scopus 로고    scopus 로고
    • ERCC1 expression is a predictor of survival in resected patients with non-small cell lung cancer
    • Simon GR, Sharma S, Cantor A, et al. ERCC1 expression is a predictor of survival in resected patients with non-small cell lung cancer. Chest 2005;127:978-983
    • (2005) Chest , vol.127 , pp. 978-983
    • Simon, G.R.1    Sharma, S.2    Cantor, A.3
  • 258
    • 42549088992 scopus 로고    scopus 로고
    • BRCA1: A novel prognostic factor in resected non-small-cell lung cancer
    • Rosell R, Shrzypski M, Jassem E, et al. BRCA1: a novel prognostic factor in resected non-small-cell lung cancer. PLoS ONE 2007;2:e1129
    • (2007) PLoS ONE , vol.2
    • Rosell, R.1    Shrzypski, M.2    Jassem, E.3
  • 259
    • 36849041454 scopus 로고    scopus 로고
    • Prognostic and predictive importance of p53 and RAS for adjuvant chemotherapy in non-small cell lung cancer
    • Tsao MS, Aviel-Ronen S, Ding K, et al. Prognostic and predictive importance of p53 and RAS for adjuvant chemotherapy in non-small cell lung cancer. J Clin Oncol 2007;25:5240-5247
    • (2007) J Clin Oncol , vol.25 , pp. 5240-5247
    • Tsao, M.S.1    Aviel-Ronen, S.2    Ding, K.3
  • 260
    • 52049090365 scopus 로고    scopus 로고
    • Role of k-RAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canadaof Canada Clinical Trials Group study BR.21
    • Zhu CQ, da Cunha Santos G, Ding K, et al. Role of k-RAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canadaof Canada Clinical Trials Group study BR.21. J Clin Oncol 2008;26:4268-4275
    • (2008) J Clin Oncol , vol.26 , pp. 4268-4275
    • Zhu, C.Q.1    Da Cunha Santos, G.2    Ding, K.3
  • 261
    • 33847416564 scopus 로고    scopus 로고
    • Class III beta-tubulin espression and benefit from adjuvant cisplatin/vinorelbine chemotheraphy in operable NSCLC: Analysis of NCIC JBR.10
    • Seve P, Lai R, Ding K, et al. Class III beta-tubulin espression and benefit from adjuvant cisplatin/vinorelbine chemotheraphy in operable NSCLC: analysis of NCIC JBR.10. Clin Cancer Res 2007;13:94-99
    • (2007) Clin Cancer Res , vol.13 , pp. 94-99
    • Seve, P.1    Lai, R.2    Ding, K.3
  • 262
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small cell lung cancer
    • Sheperd FA, Rodrigues Pereira J, Ciuleanu T, et al. Erlotinib in previously treated non-small cell lung cancer. N Engl J Med 2005;353:123-132
    • (2005) N Engl J Med , vol.353 , pp. 123-132
    • Sheperd, F.A.1    Rodrigues Pereira, J.2    Ciuleanu, T.3
  • 263
    • 12144285914 scopus 로고    scopus 로고
    • Ribonucleotide reductase messenger RNA expression and serviva in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients
    • Rosell R, Danenberg KD, Alberola V, et al. Ribonucleotide reductase messenger RNA expression and serviva in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients. Clin Cancer Res 2004;10:1318-1325
    • (2004) Clin Cancer Res , vol.10 , pp. 1318-1325
    • Rosell, R.1    Danenberg, K.D.2    Alberola, V.3
  • 264
    • 59449107777 scopus 로고    scopus 로고
    • Spanish customized adjuvant trial (SCAT) based on BRCA1 mRNA levels
    • abstract 7533
    • Cobo M Sr, Massuti B, Moràn T, et al. Spanish customized adjuvant trial (SCAT) based on BRCA1 mRNA levels. Proc Am Soc Clin Oncol 2008;26(20 Suppl):abstract 7533
    • (2008) Proc Am Soc Clin Oncol , vol.26 , Issue.20 SUPPL.
    • Cobo Sr., M.1    Massuti, B.2    Moràn, T.3
  • 265
    • 22044453790 scopus 로고    scopus 로고
    • Erlotinib in lung cancer - molecular and clinical predictors of outcome
    • Tsao MS, Sakurada A, Cutz JC, et al. Erlotinib in lung cancer - molecular and clinical predictors of outcome. N Engl Med 2005;353:133-144
    • (2005) N Engl Med , vol.353 , pp. 133-144
    • Tsao, M.S.1    Sakurada, A.2    Cutz, J.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.