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Volumn 17, Issue 2, 1999, Pages 668-675

Prognostic significance of K-ras codon 12 mutations in patients with resected stage I and II non-small-cell lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

ADENOCARCINOMA; ADULT; AGED; AMINO ACID SUBSTITUTION; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CODON; FEMALE; GENE MUTATION; HUMAN; LARGE CELL CARCINOMA; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; ONCOGENE K RAS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; SOUTHERN BLOTTING; SQUAMOUS CELL CARCINOMA;

EID: 0032975370     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/jco.1999.17.2.668     Document Type: Article
Times cited : (173)

References (43)
  • 1
    • 0030982728 scopus 로고    scopus 로고
    • Non-small cell lung cancer: Clinical value of new biological predictors
    • Graziano SL: Non-small cell lung cancer: Clinical value of new biological predictors. Lung Cancer 17:S37-S58, 1997 (suppl 1)
    • (1997) Lung Cancer , vol.17 , Issue.1 SUPPL.
    • Graziano, S.L.1
  • 2
    • 0021231694 scopus 로고
    • Prognostic factors in patients with resected stage I non-small cell lung cancer: A report from the Lung Cancer Study Group
    • Gail MH, Eagan RT, Feld R, et al: Prognostic factors in patients with resected stage I non-small cell lung cancer: A report from the Lung Cancer Study Group. Cancer 54:1802-1813, 1984
    • (1984) Cancer , vol.54 , pp. 1802-1813
    • Gail, M.H.1    Eagan, R.T.2    Feld, R.3
  • 3
    • 0023911475 scopus 로고
    • Histopathologic prognostic factors in adenocarcinomas of the peripheral lung less than 2 cm in diameter
    • Takise A, Kodama T, Shimosato Y, et al: Histopathologic prognostic factors in adenocarcinomas of the peripheral lung less than 2 cm in diameter. Cancer 61:2083-2088, 1988
    • (1988) Cancer , vol.61 , pp. 2083-2088
    • Takise, A.1    Kodama, T.2    Shimosato, Y.3
  • 4
    • 0025215880 scopus 로고
    • Prognostic and therapeutic significance of the flow cytometric nuclear DNA content in non-small cell lung cancer
    • Isobe H, Miyamoto H, Shimizu T, et al: Prognostic and therapeutic significance of the flow cytometric nuclear DNA content in non-small cell lung cancer. Cancer 65:1391-1395, 1990
    • (1990) Cancer , vol.65 , pp. 1391-1395
    • Isobe, H.1    Miyamoto, H.2    Shimizu, T.3
  • 5
    • 0023190493 scopus 로고
    • Ploidy as a prognostic determinant in surgically treated lung cancer
    • Zimmerman PV, Bint MH, Hawson GAT, et al: Ploidy as a prognostic determinant in surgically treated lung cancer. Lancet 2:530-533, 1987
    • (1987) Lancet , vol.2 , pp. 530-533
    • Zimmerman, P.V.1    Bint, M.H.2    Hawson, G.A.T.3
  • 6
    • 0025074419 scopus 로고
    • K-ras oncogene activation as a prognostic marker in adenocarcinoma of the lung
    • Slebos RJC, Kibbelaar RE, Dalesio O, et al: K-ras oncogene activation as a prognostic marker in adenocarcinoma of the lung. N Engl J Med 323:561-565, 1990
    • (1990) N Engl J Med , vol.323 , pp. 561-565
    • Slebos, R.J.C.1    Kibbelaar, R.E.2    Dalesio, O.3
  • 7
    • 0026533937 scopus 로고
    • Prognostic significance of the expression of ras oncogene product in non-small cell lung cancer
    • Harada M, Dosaka-Akita H, Miyamoto H, et al: Prognostic significance of the expression of ras oncogene product in non-small cell lung cancer. Cancer 69:72-77, 1992
    • (1992) Cancer , vol.69 , pp. 72-77
    • Harada, M.1    Dosaka-Akita, H.2    Miyamoto, H.3
  • 8
    • 0025708183 scopus 로고
    • neu expression in human lung adenocarcinomas predicts shortened survival
    • neu expression in human lung adenocarcinomas predicts shortened survival. Cancer Res 50:5184-5187, 1990
    • (1990) Cancer Res , vol.50 , pp. 5184-5187
    • Kern, J.A.1    Schwartz, D.A.2    Nordberg, J.E.3
  • 9
    • 0025810303 scopus 로고
    • Expression of blood-group antigen A: A favorable prognostic factor in non-small cell lung cancer
    • Lee JS, Ro JY, Sahin AA, et al: Expression of blood-group antigen A: A favorable prognostic factor in non-small cell lung cancer. N Engl J Med 324:1084-1090, 1991
    • (1991) N Engl J Med , vol.324 , pp. 1084-1090
    • Lee, J.S.1    Ro, J.Y.2    Sahin, A.A.3
  • 10
    • 0027473475 scopus 로고
    • Prognostic significance of p53 mutations and 3p deletions in primary resected non-small cell lung cancer
    • Horio Y, Takahashi T, Kuroishi T, et al: Prognostic significance of p53 mutations and 3p deletions in primary resected non-small cell lung cancer. Cancer Res 53:1-4, 1993
    • (1993) Cancer Res , vol.53 , pp. 1-4
    • Horio, Y.1    Takahashi, T.2    Kuroishi, T.3
  • 11
    • 0030996171 scopus 로고    scopus 로고
    • Angiogenesis as a prognostic indicator of survival in non-small-cell lung carcinoma: A prospective study
    • Fontanini G, Lucchi M, Vignati S, et al: Angiogenesis as a prognostic indicator of survival in non-small-cell lung carcinoma: A prospective study. J Natl Cancer Inst 89:881-886, 1997
    • (1997) J Natl Cancer Inst , vol.89 , pp. 881-886
    • Fontanini, G.1    Lucchi, M.2    Vignati, S.3
  • 13
    • 0023271954 scopus 로고
    • Mutational activation of the K-ras oncogene: A possible pathogenetic factor in adenocarcinoma of the lung
    • Rodenhuis S, van de Wetering MLM, Mooi WJ, et al: Mutational activation of the K-ras oncogene: A possible pathogenetic factor in adenocarcinoma of the lung. N Engl J Med 317:929-935, 1987
    • (1987) N Engl J Med , vol.317 , pp. 929-935
    • Rodenhuis, S.1    Van De Wetering, M.L.M.2    Mooi, W.J.3
  • 14
    • 0025785811 scopus 로고
    • Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines
    • Mitsudomi T, Viallet J, Mulshine JL, et al: Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines. Oncogene 6:1353-1362, 1991
    • (1991) Oncogene , vol.6 , pp. 1353-1362
    • Mitsudomi, T.1    Viallet, J.2    Mulshine, J.L.3
  • 15
    • 0026654238 scopus 로고
    • ras gene mutations as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis
    • Sugio K, Ishida T, Yokoyama H, et al: ras gene mutations as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis. Cancer Res 52:2903-2906, 1992
    • (1992) Cancer Res , vol.52 , pp. 2903-2906
    • Sugio, K.1    Ishida, T.2    Yokoyama, H.3
  • 16
    • 0024376173 scopus 로고
    • ras oncogenes in human cancer: A review
    • Bos JL: ras oncogenes in human cancer: A review. Cancer Res 49:4682-4689, 1989
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 17
    • 0023707058 scopus 로고
    • Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung
    • Rodenhuis S, Slebos RJC, Boot AJM, et al: Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung. Cancer Res 48:5738-5741, 1988
    • (1988) Cancer Res , vol.48 , pp. 5738-5741
    • Rodenhuis, S.1    Slebos, R.J.C.2    Boot, A.J.M.3
  • 18
    • 0022628932 scopus 로고
    • A new international staging system for lung cancer
    • Mountain CF: A new international staging system for lung cancer. Chest 89:225S-233S, 1986 (suppl)
    • (1986) Chest , vol.89 , Issue.SUPPL.
    • Mountain, C.F.1
  • 19
    • 0030912190 scopus 로고    scopus 로고
    • Revisions in the international system for staging lung cancer
    • Mountain CF: Revisions in the International System for staging lung cancer. Chest 111:1710-1717, 1997
    • (1997) Chest , vol.111 , pp. 1710-1717
    • Mountain, C.F.1
  • 20
    • 0020624455 scopus 로고
    • Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1
    • Shimizu K, Birnbaum D, Ruley MA, et al: Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1. Nature 304:497-500, 1983
    • (1983) Nature , vol.304 , pp. 497-500
    • Shimizu, K.1    Birnbaum, D.2    Ruley, M.A.3
  • 21
    • 0021362206 scopus 로고
    • Malignant transformation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient
    • Santos E, Martin-Zanca D, Reddy EP, et al: Malignant transformation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient. Science 223:661-664, 1984
    • (1984) Science , vol.223 , pp. 661-664
    • Santos, E.1    Martin-Zanca, D.2    Reddy, E.P.3
  • 22
    • 0021688283 scopus 로고
    • Use of cyclosporin A in establishing Epstein-Barr virus transformed human lymphoblastoid cell lines
    • Anderson MA, Gusella JF: Use of cyclosporin A in establishing Epstein-Barr virus transformed human lymphoblastoid cell lines. In Vitro 20:856-858, 1984
    • (1984) In Vitro , vol.20 , pp. 856-858
    • Anderson, M.A.1    Gusella, J.F.2
  • 24
    • 0026666288 scopus 로고
    • HTLV-I DNA sequences in CNS tissue of a patient with tropical spastic paraparesis and HTLV-I associated myelopathy
    • Iannone R, Sherman MP, Rodgers-Johnson PEB, et al: HTLV-I DNA sequences in CNS tissue of a patient with tropical spastic paraparesis and HTLV-I associated myelopathy. J Acquir Immune Defic Syndr 5:810-816, 1992
    • (1992) J Acquir Immune Defic Syndr , vol.5 , pp. 810-816
    • Iannone, R.1    Sherman, M.P.2    Rodgers-Johnson, P.E.B.3
  • 25
    • 14744300149 scopus 로고
    • Antibodies as thermolabile switches: High temperature triggering for the polymerase chain reaction
    • Sharkey DJ, Scalice ER, Christy KG Jr, et al: Antibodies as thermolabile switches: High temperature triggering for the polymerase chain reaction. Bio/Technology 12:506-509, 1994
    • (1994) Bio/Technology , vol.12 , pp. 506-509
    • Sharkey, D.J.1    Scalice, E.R.2    Christy K.G., Jr.3
  • 26
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 31
    • 0026425629 scopus 로고
    • ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent
    • Mitsudomi T, Steinberg SM, Oie HK, et al: ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent. Cancer Res 51:4999-5002, 1991
    • (1991) Cancer Res , vol.51 , pp. 4999-5002
    • Mitsudomi, T.1    Steinberg, S.M.2    Oie, H.K.3
  • 32
    • 0028324608 scopus 로고
    • C-erbB-2 expression and codon 12 K-ras mutations both predict shortened survival for patients with pulmonary adenocarcinomas
    • Kern JA, Slebos RJC, Top B, et al: C-erbB-2 expression and codon 12 K-ras mutations both predict shortened survival for patients with pulmonary adenocarcinomas. J Clin Invest 93:516-520, 1994
    • (1994) J Clin Invest , vol.93 , pp. 516-520
    • Kern, J.A.1    Slebos, R.J.C.2    Top, B.3
  • 33
    • 0028241168 scopus 로고
    • K-ras gene mutations: An unfavorable prognostic marker in stage I lung adenocarcinoma
    • Silini EM, Bosi F, Pellegata NS, et al: K-ras gene mutations: An unfavorable prognostic marker in stage I lung adenocarcinoma. Virchows Arch 424:367-373, 1994
    • (1994) Virchows Arch , vol.424 , pp. 367-373
    • Silini, E.M.1    Bosi, F.2    Pellegata, N.S.3
  • 34
    • 0028574883 scopus 로고
    • Prognostic significance of p53 and ras gene abnormalities in lung adenocarcinoma patients with stage I disease after curative resection
    • Isobe T, Hiyama K, Yoshida Y, et al: Prognostic significance of p53 and ras gene abnormalities in lung adenocarcinoma patients with stage I disease after curative resection. Jpn J Cancer Res 85:1240-1246, 1994
    • (1994) Jpn J Cancer Res , vol.85 , pp. 1240-1246
    • Isobe, T.1    Hiyama, K.2    Yoshida, Y.3
  • 35
    • 12044258694 scopus 로고
    • Prognostic impact of mutated K-ras gene in surgically resected non-small cell lung cancer patients
    • Rosell R, Li S, Skacel Z, et al: Prognostic impact of mutated K-ras gene in surgically resected non-small cell lung cancer patients. Oncogene 8:2407-2412, 1993
    • (1993) Oncogene , vol.8 , pp. 2407-2412
    • Rosell, R.1    Li, S.2    Skacel, Z.3
  • 36
    • 8944237972 scopus 로고    scopus 로고
    • Molecular staging of non-small cell lung cancer according to K-ras genotypes
    • Rosell R, Monzo M, Pifarre A, et al: Molecular staging of non-small cell lung cancer according to K-ras genotypes. Clin Cancer Res 2:1083-1086, 1996
    • (1996) Clin Cancer Res , vol.2 , pp. 1083-1086
    • Rosell, R.1    Monzo, M.2    Pifarre, A.3
  • 37
    • 9044221762 scopus 로고    scopus 로고
    • Detection of K-ras mutations in lung carcinomas: Relationship to prognosis
    • Keohavong P, DeMichele MAA, Melacrinos AC, et al: Detection of K-ras mutations in lung carcinomas: Relationship to prognosis. Clin Cancer Res 2:411-418, 1996
    • (1996) Clin Cancer Res , vol.2 , pp. 411-418
    • Keohavong, P.1    DeMichele, M.A.A.2    Melacrinos, A.C.3
  • 38
    • 0010973499 scopus 로고    scopus 로고
    • Correlation between K-ras gene mutation and prognosis of patients with nonsmall cell lung carcinoma
    • Cho JY, Kim JH, Lee YH, et al: Correlation between K-ras gene mutation and prognosis of patients with nonsmall cell lung carcinoma. Cancer 79:462-467, 1997
    • (1997) Cancer , vol.79 , pp. 462-467
    • Cho, J.Y.1    Kim, J.H.2    Lee, Y.H.3
  • 40
    • 0031922727 scopus 로고    scopus 로고
    • Prognostic value of K-ras mutations, ras oncoprotein, and c-erbB-2 oncoprotein expression in adenocarcinoma of the lung
    • Nemunaitis J, Klemow S, Tong A, et al: Prognostic value of K-ras mutations, ras oncoprotein, and c-erbB-2 oncoprotein expression in adenocarcinoma of the lung. Am J Clin Oncol 21:155-160, 1998
    • (1998) Am J Clin Oncol , vol.21 , pp. 155-160
    • Nemunaitis, J.1    Klemow, S.2    Tong, A.3
  • 41
    • 20244388951 scopus 로고    scopus 로고
    • Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: Clinical implications
    • Kwiatkowski DJ, Harpole DH Jr, Godleski J, et al: Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: Clinical implications. J Clin Oncol 16:2468-2477, 1998
    • (1998) J Clin Oncol , vol.16 , pp. 2468-2477
    • Kwiatkowski, D.J.1    Harpole D.H., Jr.2    Godleski, J.3
  • 42
    • 0026680448 scopus 로고
    • Clinical significance of ras oncogene activation in human lung cancer
    • Rodenhuis S, Slebos RJC: Clinical significance of ras oncogene activation in human lung cancer. Cancer Res 52:2665S-2669S, 1992 (suppl)
    • (1992) Cancer Res , vol.52 , Issue.SUPPL.
    • Rodenhuis, S.1    Slebos, R.J.C.2
  • 43
    • 0027209054 scopus 로고
    • Determination of tumor aggressiveness in colorectal cancer by K-ras-2 analysis
    • Finkelstein SD, Sayegh R, Bakker A, et al: Determination of tumor aggressiveness in colorectal cancer by K-ras-2 analysis. Arch Surg 128:526-532, 1993
    • (1993) Arch Surg , vol.128 , pp. 526-532
    • Finkelstein, S.D.1    Sayegh, R.2    Bakker, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.