Neurodegeneration is associated to changes in serum insulin-like growth factors

Neurobiology of Disease

Volumn 7, Issue 6, 2000, Pages 657-665

  Busiguina, Svetlana ^a   Fernandez, Ana M ^a   Barrios, Vicente ^b   Clark, Ruth ^c   Tolbert, Daniel L ^d   Berciano, Jose ^e   Torres Aleman, Ignacio ^a  

^a INSTITUTO CAJAL   (Spain)

^b HOSPITAL INFANTIL UNIVERSITARIO NIÑO JESÚS   (Spain)

^c Washington University   (Spain)

^d SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

Author keywords

Ataxia; Charcot Marie Tooth disease; Diabetes; Insulin like growth factors; Neurodegeneration

Indexed keywords

INSULIN; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ADOLESCENT; ADULT; AGED; ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA TELANGIECTASIA; CEREBELLAR ATAXIA; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC NEUROPATHY; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; INSULIN BLOOD LEVEL; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT;

EID: 0034520593     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1006/nbdi.2000.0311     Document Type: Article

References (52)

1. Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus
2. Uptake of circulating insulin-like growth factor I into the cerebrospinal fluid of normal and diabetic rats and normalization of IGF-II mRNA content in diabetic rats
3. Neurodegeneration and diabetes: UK nationwide study of Wolfram (DID-MOAD) syndrome
4. Cerebral function in diabetes mellitus
5. Specific alterations of the insulin like growth factor I system in the cerebellum of diabetic rats
6. Circulating insulin-like growth factor I mediates effects of exercise on the brain
7. Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: Relationship to severity of dementia and apolipoprotein E genotype
8. Rediscovering an old friend, IGF-I: Potential use in the treatment of neurodegenerative diseases
9. Regulation of insulin-like growth factor (IGF)-I mRNA and peptide and IGF-binding proteins by interleukin 1
10. Insulin-like growth factors regulate neuronal differentiation and survival
11. Insulin-like growth factor-I modulates c-Fos induction and astrocytosis in response to neurotoxic insult
12. Insulin-like growth factor restores motor coordination in a rat model of cerebellar ataxia
13. Neuroprotective actions of peripherally administered insulin-like growth factor I on the injured olivo-cerebellar pathway
14. Cellular actions of insulin-like growth factor binding proteins
15. Growth factors in critical illness: Regulation and therapeutic aspects
16. Charcot-Marie-Tooth disease type 1A with 17p duplication in infancy and early childhood: A longitudinal clinical and electrophysiological study
17. Duplication of part of chromosome 17 is commonly associated with hereditary motor and sensory neuropathy type I (Charcot-Marie-Tooth disease type 1)
18. Pathogenesis of Charcot-Marie-Tooth 1A (CMT1A) neuropathy
19. Genetic classification of primary neurodegenerative disease
20. Trophic factor response to neuronal stimuli or injury
21. Insulin-like growth factor I resistance
22. Insulin-like growth factors and their binding proteins: Biological actions
23. An ataxia-telangiectasia model: Inefficient cell differentiation and possible reversal by serine protease inhibitors, tumor necrosis factor inhibitors, dexamethasone, and glutathione enhancers
24. Molecular and cellular aspects of the insulin-like growth factor I receptor
25. Localization of type I insulin-like growth factor receptor messenger RNA in the adult rat brain by in situ hybridization
26. Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate
27. Transport of insulin-related peptides and glucose across the blood-brain barrier
28. Macromolecular permeability across the blood-nerve and blood-brain barriers
29. Basic fibroblast growth factor modulates insulin-like growth factor I, its receptor, and its binding proteins in hypothalamic cell cultures
30. Genetic neurodegenerative diseases: The human illness and transgenic models
31. Peripherally administered insulin-like growth factor I preserves hindlimb reflex and spinal cord noradrenergic circuitry following a central nervous system lesion in rats
32. Neuroglial activation repertoire in the injured brain: Graded response, molecular mechanisms and cues to physiological function
33. Insulin-like growth factors cross the blood-brain barrier
34. An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedreich's ataxia) gene
35. A single ataxia-telangiectasia gene with a product similar to PI-3 kinase
36. Alterations in the neural growth hormone axis following hypoxic-ischemic injury
37. Plasma insulin-like growth factor I and IGF binding protein 3 levels in patients with acute cerebral ischemia
38. Ultradian pulsatility of plasma glucose and insulin secretion rate: Circadian and sleep modulation
39. Insulin-like growth factors and insulin-like growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type
40. Spatial and temporal pattern of Purkinje cell degeneration in Shaker mutant rats with hereditary cerebellar ataxia
41. Climbing fiber deafferentation reduces insulin-like growth factor I (IGF-I) content in cerebellum
42. The insulin-like growth factor I system in cerebellar degeneration
43. The peripheral insulin-like growth factor system in amyotrophic lateral sclerosis and multiple sclerosis
44. The role of insulin-like growth factors in human neurodegeneration
45. Insulin-like growth factors as mediators of functional plasticity in the adult brain
46. When cytokines get on your nerves: Cytokine networks and CNS pathologies
47. A new mechanism of neurodegeneration: A proinflammatory cytokine inhibits receptor signaling by a survival peptide
48. An association between multiple sclerosis and type I diabetes mellitus
49. Tracking insulin to the mind
50. A behavioral study of the development of hereditary ataxia in the shaker mutant rat
51. Decreased IGF gene expression during the apoptosis of Purkinje cells in pcd mice
52. Alteration of IGF system gene expression during the postnatal development of pcd mice