메뉴 건너뛰기




Volumn 224, Issue 1, 2010, Pages 49-58

Sequential loss of cell cycle checkpoint control contributes to malignant transformation of murine embryonic fibroblasts induced by 20-methylcholanthrene

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLCHOLANTHRENE; 5 AZA 2' DEOXYCYTIDINE; CELL CYCLE PROTEIN 20; CHECKPOINT KINASE 1; CYCLIN D1; PROTEIN MAD2; PROTEIN P21; RETINOBLASTOMA PROTEIN; ANTIMETABOLITE; AZACITIDINE; CARCINOGEN; CELL CYCLE PROTEIN; DRUG DERIVATIVE;

EID: 77952505653     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22089     Document Type: Article
Times cited : (12)

References (55)
  • 2
    • 0034671768 scopus 로고    scopus 로고
    • Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
    • Alt JR, Cleveland JL, Hannink M, Diehl JA. 2000. Phosphorylation- dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. Genes Dev 14:3102-3114.
    • (2000) Genes Dev , vol.14 , pp. 3102-3114
    • Alt, J.R.1    Cleveland, J.L.2    Hannink, M.3    Diehl, J.A.4
  • 3
    • 0023580015 scopus 로고
    • Cellular and molecular mechanisms of multistep carcinogenesis: Relevance to carcinogen risk assessment
    • Barrett JC, Wiseman RW. 1987. Cellular and molecular mechanisms of multistep carcinogenesis: Relevance to carcinogen risk assessment. Environ Health Perspect 76:65-70.
    • (1987) Environ Health Perspect , vol.76 , pp. 65-70
    • Barrett, J.C.1    Wiseman, R.W.2
  • 4
    • 0035813188 scopus 로고    scopus 로고
    • Cell cycle. Order from destruction
    • New York, NY
    • Bartek J, Lukas J. 2001a. Cell cycle. Order from destruction. Science (New York, NY) 294:66-67.
    • (2001) Science , vol.294 , pp. 66-67
    • Bartek, J.1    Lukas, J.2
  • 5
    • 0035545996 scopus 로고    scopus 로고
    • Mammalian G1- and S-phase checkpoints in response to DNA damage
    • DOI 10.1016/S0955-0674(00)00280-5
    • Bartek J, Lukas J. 2001b. Mammalian G1- and S-phase checkpoints in response to DNA damage. Current opinion in cell biology 13:738-747. (Pubitemid 33042735)
    • (2001) Current Opinion in Cell Biology , vol.13 , Issue.6 , pp. 738-747
    • Bartek, J.1    Lukas, J.2
  • 6
    • 0035895622 scopus 로고    scopus 로고
    • Pathways governing G1/S transition and their response to DNA damage
    • Bartek J, Lukas J. 2001c. Pathways governing G1/S transition and their response to DNA damage. FEBS Lett 490:117-122.
    • (2001) FEBS Lett , vol.490 , pp. 117-122
    • Bartek, J.1    Lukas, J.2
  • 7
    • 0038418869 scopus 로고    scopus 로고
    • Chk1 and Chk2 kinases in checkpoint control and cancer
    • Bartek J, Lukas J. 2003. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 3:421-429.
    • (2003) Cancer Cell , vol.3 , pp. 421-429
    • Bartek, J.1    Lukas, J.2
  • 10
    • 0036884829 scopus 로고    scopus 로고
    • The retinoblastoma tumour suppressor in development and cancer
    • Classon M, Harlow E. 2002. The retinoblastoma tumour suppressor in development and cancer. Nat Rev Cancer 2:910-917.
    • (2002) Nat Rev Cancer , vol.2 , pp. 910-917
    • Classon, M.1    Harlow, E.2
  • 11
    • 21644456228 scopus 로고    scopus 로고
    • Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors
    • Collins I, Garrett MD. 2005. Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors. Curr Opin Pharmacol 5:366-373.
    • (2005) Curr Opin Pharmacol , vol.5 , pp. 366-373
    • Collins, I.1    Garrett, M.D.2
  • 12
    • 34249305203 scopus 로고    scopus 로고
    • E-cadherin repression contributes to c-Myc-induced epithelial cell transformation
    • Cowling VH, Cole MD. 2007. E-cadherin repression contributes to c-Myc-induced epithelial cell transformation. Oncogene 26:3582-3586.
    • (2007) Oncogene , vol.26 , pp. 3582-3586
    • Cowling, V.H.1    Cole, M.D.2
  • 13
    • 0030916209 scopus 로고    scopus 로고
    • Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway
    • Diehl JA, Zindy F, Sherr CJ. 1997. Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. Genes Dev 11:957-972. (Pubitemid 27199876)
    • (1997) Genes and Development , vol.11 , Issue.8 , pp. 957-972
    • Diehl, J.A.1    Zindy, F.2    Sherr, C.J.3
  • 14
    • 0035313706 scopus 로고    scopus 로고
    • DNA-PK, ATM and ATR as sensors of DNA damage: Variations on a theme?
    • Durocher D, Jackson SP. 2001. DNA-PK, ATM and ATR as sensors of DNA damage: Variations on a theme? Curr Opin Cell Biol 13:225-231.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 225-231
    • Durocher, D.1    Jackson, S.P.2
  • 15
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger G, Liang G, Aparicio A, Jones PA. 2004. Epigenetics in human disease and prospects for epigenetic therapy. Nature 429:457-463.
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 16
    • 0025068801 scopus 로고
    • Nonrandom chromosome alterations that correlate with progression to immortality in rat tracheal epithelial cells transformed with N-methyl-N'-nitro-N-nitrosoguanidine
    • Endo S, Nettesheim P, Oshimura M, Walker C. 1990. Nonrandom chromosome alterations that correlate with progression to immortality in rat tracheal epithelial cells transformed with N-methyl-N'-nitro-N-nitrosoguanidine. Cancer Res 50:740-747. (Pubitemid 20054208)
    • (1990) Cancer Research , vol.50 , Issue.3 , pp. 740-747
    • Endo, S.1    Nettesheim, P.2    Oshimura, M.3    Walker, C.4
  • 17
    • 60749129493 scopus 로고    scopus 로고
    • APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation
    • Ge S, Skaar JR, Pagano M. 2009. APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. Cell Cycle 8:167-171.
    • (2009) Cell Cycle , vol.8 , pp. 167-171
    • Ge, S.1    Skaar, J.R.2    Pagano, M.3
  • 18
    • 33748047128 scopus 로고    scopus 로고
    • RB and cell cycle progression
    • Giacinti C, Giordano A. 2006. RB and cell cycle progression. Oncogene 25:5220-5227.
    • (2006) Oncogene , vol.25 , pp. 5220-5227
    • Giacinti, C.1    Giordano, A.2
  • 19
    • 28044464730 scopus 로고    scopus 로고
    • Location, location, location: The role of cyclin D1 nuclear localization in cancer
    • Gladden AB, Diehl JA. 2005. Location, location, location: The role of cyclin D1 nuclear localization in cancer. J Cell Biochem 96:906-913.
    • (2005) J Cell Biochem , vol.96 , pp. 906-913
    • Gladden, A.B.1    Diehl, J.A.2
  • 20
    • 40449120350 scopus 로고    scopus 로고
    • An oncogene-induced DNA damage model for cancer development
    • New York, NY
    • Halazonetis TD, Gorgoulis VG, Bartek J. 2008. An oncogene-induced DNA damage model for cancer development. Science (New York, NY) 319:1352-1355.
    • (2008) Science , vol.319 , pp. 1352-1355
    • Halazonetis, T.D.1    Gorgoulis, V.G.2    Bartek, J.3
  • 21
    • 33644860073 scopus 로고    scopus 로고
    • DNA damage and tumor surveillance: One trigger for two pathways
    • Hoglund P. 2006. DNA damage and tumor surveillance: One trigger for two pathways. Sci STKE 317:pe2.
    • (2006) Sci STKE , vol.317
    • Hoglund, P.1
  • 22
    • 0037160102 scopus 로고    scopus 로고
    • Elucidation of molecular events mediating induction of apoptosis by synthetic retinoids using a CD437-resistant ovarian carcinoma cell line
    • Holmes WF, Soprano DR, Soprano KJ. 2002. Elucidation of molecular events mediating induction of apoptosis by synthetic retinoids using a CD437-resistant ovarian carcinoma cell line. J Biol Chem 277:45408-45419.
    • (2002) J Biol Chem , vol.277 , pp. 45408-45419
    • Holmes, W.F.1    Soprano, D.R.2    Soprano, K.J.3
  • 26
    • 43249104714 scopus 로고    scopus 로고
    • Different mutant/ wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells
    • Junk DJ, Vrba L, Watts GS, Oshiro MM, Martinez JD, Futscher BW. 2008. Different mutant/ wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells. Neoplasia 10:450-461.
    • (2008) Neoplasia , vol.10 , pp. 450-461
    • Junk, D.J.1    Vrba, L.2    Watts, G.S.3    Oshiro, M.M.4    Martinez, J.D.5    Futscher, B.W.6
  • 27
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • Kastan MB, Bartek J. 2004. Cell-cycle checkpoints and cancer. Nature 432:316-323.
    • (2004) Nature , vol.432 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 30
    • 37349064784 scopus 로고    scopus 로고
    • Molecular mechanisms of cellular senescence and immortalization of human cells
    • Kiyono T. 2007. Molecular mechanisms of cellular senescence and immortalization of human cells. Expert Opin Ther Targets 11:1623-1637.
    • (2007) Expert Opin Ther Targets , vol.11 , pp. 1623-1637
    • Kiyono, T.1
  • 31
    • 0031022037 scopus 로고    scopus 로고
    • G2 cell cycle arrest and apoptosis are induced in Burkitt's lymphoma cells by the anticancer agent oracin
    • Klucar J, Al-Rubeai M. 1997. G2 cell cycle arrest and apoptosis are induced in Burkitt's lymphoma cells by the anticancer agent oracin. FEBS Lett 400:127-130.
    • (1997) FEBS Lett , vol.400 , pp. 127-130
    • Klucar, J.1    Al-Rubeai, M.2
  • 32
    • 0347717882 scopus 로고    scopus 로고
    • Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway
    • Lee S, Helfman DM. 2004. Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway. J Biol Chem 279:1885-1891.
    • (2004) J Biol Chem , vol.279 , pp. 1885-1891
    • Lee, S.1    Helfman, D.M.2
  • 33
    • 7044271231 scopus 로고    scopus 로고
    • Mad2 and p27 expression profiles in colorectal cancer and its clinical significance
    • Li GQ, Zhang HF. 2004. Mad2 and p27 expression profiles in colorectal cancer and its clinical significance. World J Gastroenterol 10:3218-3220. (Pubitemid 39419895)
    • (2004) World Journal of Gastroenterology , vol.10 , Issue.21 , pp. 3218-3220
    • Li, G.-Q.1    Zhang, H.-F.2
  • 34
    • 57749116048 scopus 로고    scopus 로고
    • Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation
    • Li Z, Boone D, Hann SR. 2008. Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation. Proc Natl Acad Sci USA 105: 18794-18799.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 18794-18799
    • Li, Z.1    Boone, D.2    Hann, S.R.3
  • 35
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 37
    • 25844504743 scopus 로고    scopus 로고
    • Modulation of cell cycle components by epigenetic and genetic events
    • Macaluso M, Montanari M, Cinti C, Giordano A. 2005. Modulation of cell cycle components by epigenetic and genetic events. Semin Oncol 32:452-457.
    • (2005) Semin Oncol , vol.32 , pp. 452-457
    • Macaluso, M.1    Montanari, M.2    Cinti, C.3    Giordano, A.4
  • 38
    • 60749109846 scopus 로고    scopus 로고
    • Cell cycle, CDKs and cancer: A changing paradigm
    • Malumbres M, Barbacid M. 2009. Cell cycle, CDKs and cancer: A changing paradigm. Nat Rev Cancer 9:153-166.
    • (2009) Nat Rev Cancer , vol.9 , pp. 153-166
    • Malumbres, M.1    Barbacid, M.2
  • 39
    • 0029572456 scopus 로고
    • Neoplastic transformation of normal rat embryo fibroblasts by a mutated p53 and an activated ras oncogene induces parathyroid hormone-related peptide gene expression and causes hypercalcemia in nude mice
    • Motokura T, Endo K, Kumaki K, Ogata E, Ikeda K. 1995. Neoplastic transformation of normal rat embryo fibroblasts by a mutated p53 and an activated ras oncogene induces parathyroid hormone-related peptide gene expression and causes hypercalcemia in nude mice. J Biol Chem 270:30857-30861. (Pubitemid 126634580)
    • (1995) Journal of Biological Chemistry , vol.270 , Issue.52 , pp. 30857-30861
    • Motokura, T.1    Endo, K.2    Kumaki, K.3    Ogata, E.4    Ikeda, K.5
  • 40
    • 0026526356 scopus 로고
    • Partial characterization, progressive development and correlations of some neoplastic characters in 20-methylcholanthrene-induced transformed murine embryonal fibroblasts
    • Mukherjee P, Das SK. 1992. Partial characterization, progressive development and correlations of some neoplastic characters in 20-methylcholanthrene-induced transformed murine embryonal fibroblasts. Cancer Lett 67:1-12.
    • (1992) Cancer Lett , vol.67 , pp. 1-12
    • Mukherjee, P.1    Das, S.K.2
  • 41
    • 57049097535 scopus 로고    scopus 로고
    • The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction
    • Nilsson J, Yekezare M, Minshull J, Pines J. 2008. The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction. Nat Cell Biol 10:1411-1420.
    • (2008) Nat Cell Biol , vol.10 , pp. 1411-1420
    • Nilsson, J.1    Yekezare, M.2    Minshull, J.3    Pines, J.4
  • 42
    • 0032554775 scopus 로고    scopus 로고
    • Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21(Cip1) and p27(Kip1) in anchorage-independent cells
    • Orend G, Hunter T, Ruoslahti E. 1998. Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21Cip1 and p27Kip1 in anchorage-independent cells. Oncogene 16:2575-2583. (Pubitemid 28264035)
    • (1998) Oncogene , vol.16 , Issue.20 , pp. 2575-2583
    • Orend, G.1    Hunter, T.2    Ruoslahti, E.3
  • 43
    • 0642286495 scopus 로고    scopus 로고
    • Cyclin B1 and CDK1: Nuclear localization and upstream regulators
    • Porter LA, Donoghue DJ. 2003. Cyclin B1 and CDK1: Nuclear localization and upstream regulators. Prog Cell Cycle Res 5:335-347.
    • (2003) Prog Cell Cycle Res , vol.5 , pp. 335-347
    • Porter, L.A.1    Donoghue, D.J.2
  • 46
    • 27144458683 scopus 로고    scopus 로고
    • Cyclins and CDKS in development and cancer: Lessons from genetically modified mice
    • Santamaria D, Ortega S. 2006. Cyclins and CDKS in development and cancer: Lessons from genetically modified mice. Front Biosci 11:1164-1188. (Pubitemid 43253468)
    • (2006) Frontiers in Bioscience , vol.11 , Issue.1 , pp. 1164-1188
    • Santamaria, D.1    Ortega, S.2
  • 47
    • 57349158759 scopus 로고    scopus 로고
    • Chromosome instability and tumor lethality suppression in carcinogenesis
    • Shen C, Zhou Y, Zhan J, Reske SN, Buck AK. 2008. Chromosome instability and tumor lethality suppression in carcinogenesis. J Cell Biochem 105:1327-1341.
    • (2008) J Cell Biochem , vol.105 , pp. 1327-1341
    • Shen, C.1    Zhou, Y.2    Zhan, J.3    Reske, S.N.4    Buck, A.K.5
  • 51
    • 32044443208 scopus 로고    scopus 로고
    • The retinoblastoma protein is required for Ras-induced oncogenic transformation
    • Williams JP, Stewart T, Li B, Mulloy R, Dimova D, Classon M. 2006. The retinoblastoma protein is required for Ras-induced oncogenic transformation. Mol Cell Biol 26:1170-1182.
    • (2006) Mol Cell Biol , vol.26 , pp. 1170-1182
    • Williams, J.P.1    Stewart, T.2    Li, B.3    Mulloy, R.4    Dimova, D.5    Classon, M.6
  • 52
    • 2642527955 scopus 로고    scopus 로고
    • Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation
    • Woo RA, Poon RY. 2004. Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation. Genes Dev 18:1317-1330.
    • (2004) Genes Dev , vol.18 , pp. 1317-1330
    • Woo, R.A.1    Poon, R.Y.2
  • 53
    • 1342267616 scopus 로고    scopus 로고
    • The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer
    • Yoshida T, Tanaka S, Mogi A, Shitara Y, Kuwano H. 2004. The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer. Ann Oncol 15:252-256.
    • (2004) Ann Oncol , vol.15 , pp. 252-256
    • Yoshida, T.1    Tanaka, S.2    Mogi, A.3    Shitara, Y.4    Kuwano, H.5
  • 54
    • 0030918714 scopus 로고    scopus 로고
    • Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases
    • Zarkowska T, Mittnacht S. 1997. Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases. J Biol Chem 272:12738-12746.
    • (1997) J Biol Chem , vol.272 , pp. 12738-12746
    • Zarkowska, T.1    Mittnacht, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.