-
2
-
-
0037195631
-
Historical essay. the early years of HIV/AIDS
-
Gallo RC: Historical essay. The early years of HIV/AIDS. Science 298(5599), 1728-1730 (2002).
-
(2002)
Science
, vol.298
, Issue.5599
, pp. 1728-1730
-
-
Gallo, R.C.1
-
3
-
-
0345097633
-
The discovery of HIV as the cause of AIDS
-
Gallo RC, Montagnier L: The discovery of HIV as the cause of AIDS. N. Engl. J. Med. 349(24), 2283-2285 (2003).
-
(2003)
N. Engl. J. Med
, vol.349
, Issue.24
, pp. 2283-2285
-
-
Gallo, R.C.1
Montagnier, L.2
-
4
-
-
0037195627
-
Historical essay. A history of HIV discovery
-
Montagnier L: Historical essay. A history of HIV discovery. Science 298(5599), 1727-1728 (2002).
-
(2002)
Science
, vol.298
, Issue.5599
, pp. 1727-1728
-
-
Montagnier, L.1
-
5
-
-
45549102073
-
Expanding global HIV treatment: Case studies from the feld
-
Furin JJ, Behforouz HL, Shin SS et al.: Expanding global HIV treatment: Case studies from the feld. Ann. NY Acad. Sci. 1136, 12-20 (2008).
-
(2008)
Ann. NY Acad. Sci
, vol.1136
, pp. 12-20
-
-
Furin, J.J.1
Behforouz, H.L.2
Shin, S.S.3
-
6
-
-
33744959926
-
The HIV-AIDS pandemic at 25-the global response
-
Merson MH: The HIV-AIDS pandemic at 25-the global response. N. Engl J. Med. 354(23), 2414-2417 (2006).
-
(2006)
N. Engl J. Med
, vol.354
, Issue.23
, pp. 2414-2417
-
-
Merson, M.H.1
-
8
-
-
70449688310
-
Patent life of antiretroviral drugs approved in the US from 1987 to 2007
-
Rodriguez-Monguio R, Seoane-Vazquez E: Patent life of antiretroviral drugs approved in the US from 1987 to 2007. AIDS Care 1-9 (2009).
-
AIDS Care
, vol.2009
, pp. 1-9
-
-
Rodriguez-Monguio, R.1
Seoane-Vazquez, E.2
-
9
-
-
59849116763
-
FDA grants tentative approval for 75th generic antiretroviral drug
-
Lang L: FDA grants tentative approval for 75th generic antiretroviral drug. Gastroenterology 136(1), 5 (2009).
-
(2009)
Gastroenterology
, vol.136
, Issue.1
, pp. 5
-
-
Lang, L.1
-
10
-
-
33745222568
-
The survival benefts of AIDS treatment in the United States
-
Walensky R P, Paltiel AD, Losina E et al.: The survival benefts of AIDS treatment in the United States. J. Infect. Dis. 194(1), 11-19 (2006).
-
(2006)
J. Infect. Dis
, vol.194
, Issue.1
, pp. 11-19
-
-
Walensky, R.P.1
Paltiel, A.D.2
Losina, E.3
-
11
-
-
62249095476
-
The challenge of fnding a cure for HIV infection
-
Richman DD, Margolis DM, Delaney M, Greene WC, Hazuda D, Pomerantz RJ: The challenge of fnding a cure for HIV infection. Science 323(5919), 1304-1307 (2009).
-
(2009)
Science
, vol.323
, Issue.5919
, pp. 1304-1307
-
-
Richman, D.D.1
Margolis, D.M.2
Delaney, M.3
Greene, W.C.4
Hazuda, D.5
Pomerantz, R.J.6
-
12
-
-
0035912249
-
HIV chemotherapy
-
Richman DD: HIV chemotherapy. Nature 410(6831), 995-1001 (2001).
-
(2001)
Nature
, vol.410
, Issue.6831
, pp. 995-1001
-
-
Richman, D.D.1
-
13
-
-
38049067731
-
Merck's HIV vaccine fop brings vectors under closer scrutiny
-
Ledford H: Merck's HIV vaccine fop brings vectors under closer scrutiny. Nat. Biotechnol. 26(1), 3-4 (2008).
-
(2008)
Nat. Biotechnol
, vol.26
, Issue.1
, pp. 3-4
-
-
Ledford, H.1
-
14
-
-
44949125587
-
HIV vaccine developers battle on, despite high-profle failures
-
Ledford H: HIV vaccine developers battle on, despite high-profle failures. Nat. Biotechnol. 26(6), 591-592 (2008).
-
(2008)
Nat. Biotechnol
, vol.26
, Issue.6
, pp. 591-592
-
-
Ledford, H.1
-
15
-
-
50849126803
-
HIV vaccine development in the aftermath of the step study: Re-focus on occult HIV infection?
-
Uberla K: HIV vaccine development in the aftermath of the step study: Re-focus on occult HIV infection? PLoS Pathog. 4(8), e1000114 (2008).
-
(2008)
PLoS Pathog
, vol.4
, Issue.8
-
-
Uberla, K.1
-
16
-
-
39749190011
-
Aids research. Microbicide fails to protect against HIV
-
Cohen J: Aids research. Microbicide fails to protect against HIV. Science 319(5866), 1026-1027 (2008).
-
(2008)
Science
, vol.319
, Issue.5866
, pp. 1026-1027
-
-
Cohen, J.1
-
17
-
-
48249121565
-
Whither or wither microbicides?
-
Grant RM, Hamer D, Hope T et al.: Whither or wither microbicides? Science 321(5888), 532-534 (2008).
-
(2008)
Science
, vol.321
, Issue.5888
, pp. 532-534
-
-
Grant, R.M.1
Hamer, D.2
Hope, T.3
-
18
-
-
54049111463
-
Nanotechnology for drug delivery: The perfect partnership
-
Farokhzad OC: Nanotechnology for drug delivery: The perfect partnership. Expert Opin. Drug Deliv. 5(9), 927-929 (2008).
-
(2008)
Expert Opin. Drug Deliv
, vol.5
, Issue.9
, pp. 927-929
-
-
Farokhzad, O.C.1
-
19
-
-
42349094203
-
Nanoparticles in medicine: Therapeutic applications and developments
-
Zhang L, Gu FX, Chan JM, Wang AZ, Langer RS, Farokhzad OC: Nanoparticles in medicine: Therapeutic applications and developments. Clin. Pharmacol. Ther. 83(5), 761-769 (2008).
-
(2008)
Clin. Pharmacol. Ther
, vol.83
, Issue.5
, pp. 761-769
-
-
Zhang, L.1
Gu, F.X.2
Chan, J.M.3
Wang, A.Z.4
Langer, R.S.5
Farokhzad, O.C.6
-
20
-
-
14644439267
-
Cancer nanotechnology: Opportunities and challenges
-
Ferrari M: Cancer nanotechnology: Opportunities and challenges. Nat. Rev. Cancer 5(3), 161-171 (2005).
-
(2005)
Nat. Rev. Cancer
, vol.5
, Issue.3
, pp. 161-171
-
-
Ferrari, M.1
-
21
-
-
35348882024
-
Nanotechnology applications in cancer
-
Nie S, Xing Y, Kim GJ, Simons JW: Nanotechnology applications in cancer. Annu. Rev. Biomed. Eng. 9, 257-288 (2007).
-
(2007)
Annu. Rev. Biomed. Eng
, vol.9
, pp. 257-288
-
-
Nie, S.1
Xing, Y.2
Kim, G.J.3
Simons, J.W.4
-
22
-
-
39649092973
-
Nanotechnology and cancer
-
Heath JR, Davis ME: Nanotechnology and cancer. Ann. Rev. Med. 59, 251-265 (2008).
-
(2008)
Ann. Rev. Med
, vol.59
, pp. 251-265
-
-
Heath, J.R.1
Davis, M.E.2
-
23
-
-
19944431012
-
Predictors of HIV drug-resistance mutations in a large antiretroviral-naive cohort initiating triple antiretroviral therapy
-
Harrigan PR, Hogg RS, Dong WW et al.: Predictors of HIV drug-resistance mutations in a large antiretroviral-naive cohort initiating triple antiretroviral therapy. J. Infect. Dis. 191(3), 339-347 (2005).
-
(2005)
J. Infect. Dis
, vol.191
, Issue.3
, pp. 339-347
-
-
Harrigan, P.R.1
Hogg, R.S.2
Dong, W.W.3
-
24
-
-
0033613342
-
Re-emergence of HIV after stopping therapy
-
Chun TW, Davey RT Jr, Engel D, Lane HC, Fauci AS: Re-emergence of HIV after stopping therapy. Nature 401(6756), 874-875 (1999).
-
(1999)
Nature
, vol.401
, Issue.6756
, pp. 874-875
-
-
Chun, T.W.1
Davey Jr, R.T.2
Engel, D.3
Lane, H.C.4
Fauci, A.S.5
-
25
-
-
57649193118
-
Eradication of HIV: Current challenges and new directions
-
Marsden MD, Zack JA: Eradication of HIV: Current challenges and new directions. J. Antimicrob. Chemother. 63(1), 7-10 (2009).
-
(2009)
J. Antimicrob. Chemother
, vol.63
, Issue.1
, pp. 7-10
-
-
Marsden, M.D.1
Zack, J.A.2
-
26
-
-
77952501016
-
-
Physicians' Press, Royal Oak, MI, USA
-
Sax PE, Cohen CJ, Kuritzkes DR: HIV Essentials. Physicians' Press, Royal Oak, MI, USA (2007).
-
(2007)
HIV Essentials
-
-
Sax, P.E.1
Cohen, C.J.2
Kuritzkes, D.R.3
-
27
-
-
63749110947
-
Extensive HIV-1 intra-host recombination is common in tissues with abnormal histopathology
-
Lamers SL, Salemi M, Galligan DC et al.: Extensive HIV-1 intra-host recombination is common in tissues with abnormal histopathology. PLoS One 4(3), E5065 (2009).
-
(2009)
PLoS One
, vol.4
, Issue.3
-
-
Lamers, S.L.1
Salemi, M.2
Galligan, D.C.3
-
28
-
-
33748143806
-
HIV pharmacology: Barriers to the eradication of HIV from the CNS, HIV Clin
-
McGee B, Smith N, Aweeka F: HIV pharmacology: Barriers to the eradication of HIV from the CNS. HIV Clin. Trials 7(3), 142-153 (2006).
-
(2006)
Trials
, vol.7
, Issue.3
, pp. 142-153
-
-
McGee, B.1
Smith, N.2
Aweeka, F.3
-
29
-
-
33748669829
-
Nanoparticulate drug carriers for delivery of HIV/AIDS therapy to viral reservoir sites
-
Vyas TK, Shah L, Amiji MM: Nanoparticulate drug carriers for delivery of HIV/AIDS therapy to viral reservoir sites. Expert Opin. Drug Deliv. 3(5), 613-628 (2006).
-
(2006)
Expert Opin. Drug Deliv
, vol.3
, Issue.5
, pp. 613-628
-
-
Vyas, T.K.1
Shah, L.2
Amiji, M.M.3
-
30
-
-
34848891527
-
Peritoneal macrophage uptake, pharmacokinetics and biodistribution of macrophage-targeted peg-fmlf (n-formyl-methionyl-leucyl-phenylalanine) nanocarriers for improving HIV drug delivery
-
Wan L, Pooyan S, Hu P, Leibowitz MJ, Stein S, Sinko PJ: Peritoneal macrophage uptake, pharmacokinetics and biodistribution of macrophage-targeted peg-fmlf (n-formyl-methionyl-leucyl-phenylalanine) nanocarriers for improving HIV drug delivery. Pharm. Res. 24(11), 2110-2119 (2007).
-
(2007)
Pharm. Res
, vol.24
, Issue.11
, pp. 2110-2119
-
-
Wan, L.1
Pooyan, S.2
Hu, P.3
Leibowitz, M.J.4
Stein, S.5
Sinko, P.J.6
-
31
-
-
68249144974
-
Nanoart, neuroAIDS and CNS drug delivery
-
Nowacek A, Gendelman HE: Nanoart, neuroAIDS and CNS drug delivery. Nanomed. 4(5), 557-574 (2009).
-
(2009)
Nanomed
, vol.4
, Issue.5
, pp. 557-574
-
-
Nowacek, A.1
Gendelman, H.E.2
-
32
-
-
61849153021
-
Impact of nanotechnology on drug delivery
-
Farokhzad OC, Langer R: Impact of nanotechnology on drug delivery. ACS Nano 3(1), 16-20 (2009).
-
(2009)
ACS Nano
, vol.3
, Issue.1
, pp. 16-20
-
-
Farokhzad, O.C.1
Langer, R.2
-
33
-
-
51049090204
-
Nanoparticle therapeutics: An emerging treatment modality for cancer
-
Davis ME, Chen ZG, Shin DM: Nanoparticle therapeutics: An emerging treatment modality for cancer. Nat. Rev. Drug Discov. 7(9), 771-782 (2008).
-
(2008)
Nat. Rev. Drug Discov
, vol.7
, Issue.9
, pp. 771-782
-
-
Davis, M.E.1
Chen, Z.G.2
Shin, D.M.3
-
34
-
-
54049123870
-
Role of nanotechnology in HIV/AIDS treatment: Potential to overcome the viral reservoir challenge
-
Amiji MM, Vyas TK, Shah LK: Role of nanotechnology in HIV/AIDS treatment: Potential to overcome the viral reservoir challenge. Discov. Med. 6(34), 157-162 (2006).
-
(2006)
Discov. Med
, vol.6
, Issue.34
, pp. 157-162
-
-
Amiji, M.M.1
Vyas, T.K.2
Shah, L.K.3
-
35
-
-
67449119172
-
Development of a long-acting injectable formulation with nanoparticles of rilpivirine (tmc278) for HIV treatment
-
Baert L, van't Klooster G, Dries W et al.: Development of a long-acting injectable formulation with nanoparticles of rilpivirine (tmc278) for HIV treatment. Eur. J. Pharm. Biopharm. 72(3), 502-508 (2009).
-
(2009)
Eur. J. Pharm. Biopharm
, vol.72
, Issue.3
, pp. 502-508
-
-
Baert, L.1
Van'T Klooster, G.2
Dries, W.3
-
36
-
-
33750611615
-
Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery
-
Dou H, Destache CJ, Morehead JR et al.: Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery. Blood 108(8), 2827-2835 (2006).
-
(2006)
Blood
, vol.108
, Issue.8
, pp. 2827-2835
-
-
Dou, H.1
Destache, C.J.2
Morehead, J.R.3
-
37
-
-
33845965983
-
Laboratory investigations for the morphologic, pharmacokinetic, and anti-retroviral properties of indinavir nanoparticles in human monocyte-derived macrophages
-
Dou H, Morehead J, Destache CJ et al.: Laboratory investigations for the morphologic, pharmacokinetic, and anti-retroviral properties of indinavir nanoparticles in human monocyte-derived macrophages. Virology 358(1), 148-158 (2007).
-
(2007)
Virology
, vol.358
, Issue.1
, pp. 148-158
-
-
Dou, H.1
Morehead, J.2
Destache, C.J.3
-
38
-
-
68949102075
-
Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS
-
Dou H, Grotepas CB, McMillan JM et al.: Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS. J. Immunol. 183(1), 661-669 (2009).
-
(2009)
J. Immunol
, vol.183
, Issue.1
, pp. 661-669
-
-
Dou, H.1
Grotepas, C.B.2
McMillan, J.M.3
-
39
-
-
33646439685
-
Stavudine-loaded mannosylated liposomes: In-vitro anti-HIV-i activity, tissue distribution and pharmacokinetics
-
Garg M, Asthana A, Agashe HB, Agrawal GP, Jain NK: Stavudine-loaded mannosylated liposomes: In-vitro anti-HIV-i activity, tissue distribution and pharmacokinetics. J. Pharm. Pharmacol. 58(5), 605-616 (2006).
-
(2006)
J. Pharm. Pharmacol
, vol.58
, Issue.5
, pp. 605-616
-
-
Garg, M.1
Asthana, A.2
Agashe, H.B.3
Agrawal, G.P.4
Jain, N.K.5
-
40
-
-
34250891378
-
Reduced hepatic toxicity, enhanced cellular uptake and altered pharmacokinetics of stavudine loaded galactosylated liposomes
-
Garg M, Dutta T, Jain NK: Reduced hepatic toxicity, enhanced cellular uptake and altered pharmacokinetics of stavudine loaded galactosylated liposomes. Eur. J. Pharm. Biopharm. 67(1), 76-85 (2007).
-
(2007)
Eur. J. Pharm. Biopharm
, vol.67
, Issue.1
, pp. 76-85
-
-
Garg, M.1
Dutta, T.2
Jain, N.K.3
-
41
-
-
39749174284
-
Radiolabeling, pharmacoscintigraphic evaluation and antiretroviral effcacy of stavudine loaded 99mtc labeled galactosylated liposomes
-
Garg M, Garg BR, Jain S et al.: Radiolabeling, pharmacoscintigraphic evaluation and antiretroviral effcacy of stavudine loaded 99mtc labeled galactosylated liposomes. Eur. J. Pharm. Sci. 33(3), 271-281 (2008).
-
(2008)
Eur. J. Pharm. Sci
, vol.33
, Issue.3
, pp. 271-281
-
-
Garg, M.1
Garg, B.R.2
Jain, S.3
-
42
-
-
56349171767
-
Lymphatic targeting of zidovudine using surface-engineered liposomes
-
Kaur CD, Nahar M, Jain NK: Lymphatic targeting of zidovudine using surface-engineered liposomes. J. Drug Target 16(10), 798-805 (2008).
-
(2008)
J. Drug Target
, vol.16
, Issue.10
, pp. 798-805
-
-
Kaur, C.D.1
Nahar, M.2
Jain, N.K.3
-
43
-
-
33847116733
-
Poly (propyleneimine) dendrimer based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro
-
Dutta T, Agashe HB, Garg M, Balakrishnan P, Kabra M, Jain NK: Poly (propyleneimine) dendrimer based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro. J. Drug Target 15(1), 89-98 (2007).
-
(2007)
J. Drug Target
, vol.15
, Issue.1
, pp. 89-98
-
-
Dutta, T.1
Agashe, H.B.2
Garg, M.3
Balakrishnan, P.4
Kabra, M.5
Jain, N.K.6
-
44
-
-
33847174124
-
Targeting potential and anti-HIV activity of lamivudine loaded mannosylated poly (propyleneimine) dendrimer
-
Dutta T, Jain NK: Targeting potential and anti-HIV activity of lamivudine loaded mannosylated poly (propyleneimine) dendrimer. Biochim. Biophys. Acta 1770(4), 681-686 (2007).
-
(2007)
Biochim. Biophys. Acta
, vol.1770
, Issue.4
, pp. 681-686
-
-
Dutta, T.1
Jain, N.K.2
-
45
-
-
44349124455
-
Targeting of efavirenz loaded tuftsin conjugated poly(propyleneimine) dendrimers to HIV infected macrophages in vitro
-
Dutta T, Garg M, Jain NK: Targeting of efavirenz loaded tuftsin conjugated poly(propyleneimine) dendrimers to HIV infected macrophages in vitro. Eur. J. Pharm. Sci. 34(2-3), 181-189 (2008).
-
(2008)
Eur. J. Pharm. Sci
, vol.34
, Issue.2-3
, pp. 181-189
-
-
Dutta, T.1
Garg, M.2
Jain, N.K.3
-
46
-
-
38949216354
-
Optimizing size and copy number for PEG-FMLF (n-formyl-methionyl-leucyl- phenylalanine) nanocarrier uptake by macrophages
-
Wan L, Zhang X, Pooyan S et al.: Optimizing size and copy number for PEG-FMLF (n-formyl-methionyl-leucyl-phenylalanine) nanocarrier uptake by macrophages. Bioconjug. Chem. 19(1), 28-38 (2008).
-
(2008)
Bioconjug. Chem
, vol.19
, Issue.1
, pp. 28-38
-
-
Wan, L.1
Zhang, X.2
Pooyan, S.3
-
48
-
-
67549109069
-
X-ray structures of the hexameric building block of the HIV capsid
-
Pornillos O, Ganser-Pornillos BK, Kelly BN et al.: X-ray structures of the hexameric building block of the HIV capsid. Cell 137(7), 1282-1292 (2009).
-
(2009)
Cell
, vol.137
, Issue.7
, pp. 1282-1292
-
-
Pornillos, O.1
Ganser-Pornillos, B.K.2
Kelly, B.N.3
-
49
-
-
0027244713
-
Inhibition of the HIV-1 protease by fullerene derivatives-model-building studies and experimental-verifcation
-
Friedman SH, Decamp DL, Sijbesma R P, Srdanov G, Wudl F, Kenyon GL: Inhibition of the HIV-1 protease by fullerene derivatives-model-building studies and experimental-verifcation. J. Am. Chem. Soc. 115(15), 6506-6509 (1993).
-
(1993)
J. Am. Chem. Soc
, vol.115
, Issue.15
, pp. 6506-6509
-
-
Friedman, S.H.1
Decamp, D.L.2
Sijbesma, R.P.3
Srdanov, G.4
Wudl, F.5
Kenyon, G.L.6
-
50
-
-
0344495996
-
Synthesis and anti-HIV properties of new water-soluble bis-functionalized[60] fullerene derivatives
-
Bosi S, Da Ros T, Spalluto G, Balzarini J, Prato M: Synthesis and anti-HIV properties of new water-soluble bis-functionalized[60] fullerene derivatives. Bioorg. Med. Chem. Lett. 13(24), 4437-4440 (2003).
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, Issue.24
, pp. 4437-4440
-
-
Bosi, S.1
Da Ros, T.2
Spalluto, G.3
Balzarini, J.4
Prato, M.5
-
51
-
-
0344550382
-
Nanobionics of pharmacologically active derivatives of fullerene c-60
-
Kotelnikova RA, Bogdanov GN, Frog EC et al.: Nanobionics of pharmacologically active derivatives of fullerene c-60. J. Nanopart. Res. 5(5-6), 561-566 (2003).
-
(2003)
J. Nanopart. Res
, vol.5
, Issue.5-6
, pp. 561-566
-
-
Kotelnikova, R.A.1
Bogdanov, G.N.2
Frog, E.C.3
-
52
-
-
21744449445
-
Anti-HIV properties of cationic fullerene derivatives
-
Marchesan S, Da Ros T, Spalluto G, Balzarini J, Prato M: Anti-HIV properties of cationic fullerene derivatives. Bioorg. Med. Chem. Lett. 15(15), 3615-3618 (2005).
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, Issue.15
, pp. 3615-3618
-
-
Marchesan, S.1
Da Ros, T.2
Spalluto, G.3
Balzarini, J.4
Prato, M.5
-
53
-
-
34547888000
-
Chlorofullerene c60cl6: A precursor for straightforward preparation of highly water-soluble polycarboxylic fullerene derivatives active against HIV
-
Troshina OA, Troshin PA, Peregudov AS, Kozlovskiy VI, Balzarini J, Lyubovskaya RN: Chlorofullerene c60cl6: A precursor for straightforward preparation of highly water-soluble polycarboxylic fullerene derivatives active against HIV. Org. Biomol. Chem. 5(17), 2783-2791 (2007).
-
(2007)
Org. Biomol. Chem
, vol.5
, Issue.17
, pp. 2783-2791
-
-
Troshina, O.A.1
Troshin, P.A.2
Peregudov, A.S.3
Kozlovskiy, V.I.4
Balzarini, J.5
Lyubovskaya, R.N.6
-
54
-
-
66249124254
-
In silico drug screening approach for the design of magic bullets: A successful example with anti-HIV fullerene derivatized amino acids
-
Durdagi S, Supuran CT, Strom TA et al.: In silico drug screening approach for the design of magic bullets: A successful example with anti-HIV fullerene derivatized amino acids. J. Chem. Inf. Model 49(5), 1139-1143 (2009).
-
(2009)
J. Chem. Inf. Model
, vol.49
, Issue.5
, pp. 1139-1143
-
-
Durdagi, S.1
Supuran, C.T.2
Strom, T.A.3
-
55
-
-
56349143017
-
Target-selective photo-degradation of HIV-1 protease by a fullerene-sugar hybrid
-
Tanimoto S, Sakai S, Matsumura S, Takahashi D, Toshima K: Target-selective photo-degradation of HIV-1 protease by a fullerene-sugar hybrid. Chem. Commun. (44), 5767-5769 (2008).
-
(2008)
Chem. Commun.
, vol.44
, pp. 5767-5769
-
-
Tanimoto, S.1
Sakai, S.2
Matsumura, S.3
Takahashi, D.4
Toshima, K.5
-
56
-
-
33846262516
-
Dendritic catanionic assemblies: In vitro anti-HIV activity of phosphorus-containing dendrimers bearing gal beta(1)cer analogues
-
Blanzat M, Turrin CO, Aubertin AM et al.: Dendritic catanionic assemblies: In vitro anti-HIV activity of phosphorus-containing dendrimers bearing gal beta(1)cer analogues. Chembiochem. 6(12), 2207-2213 (2005).
-
(2005)
Chembiochem.
, vol.6
, Issue.12
, pp. 2207-2213
-
-
Blanzat, M.1
Turrin, C.O.2
Aubertin, A.M.3
-
57
-
-
33845580811
-
Infuence of generation 2-5 of pamam dendrimer on the inhibition of tat peptide/tar rna binding in HIV-1 transcription
-
Wang W, Guo ZP, Chen Y, Liu T, Jiang L: Infuence of generation 2-5 of pamam dendrimer on the inhibition of tat peptide/tar rna binding in HIV-1 transcription. Chem. Biol. Drug Des. 68(6), 314-318 (2006).
-
(2006)
Chem. Biol. Drug des
, vol.68
, Issue.6
, pp. 314-318
-
-
Wang, W.1
Guo, Z.P.2
Chen, Y.3
Liu, T.4
Jiang, L.5
-
59
-
-
27644459894
-
Silver nanoparticles fabricated in hepes buffer exhibit cytoprotective activities toward HIV-1 infected cells
-
Sun RW, Chen R, Chung NP, Ho CM, Lin CL, Che CM: Silver nanoparticles fabricated in hepes buffer exhibit cytoprotective activities toward HIV-1 infected cells. Chem. Commun. (40), 5059-5061 (2005).
-
(2005)
Chem. Commun.
, vol.40
, pp. 5059-5061
-
-
Sun, R.W.1
Chen, R.2
Chung, N.P.3
Ho, C.M.4
Lin, C.L.5
Che, C.M.6
-
60
-
-
44449133739
-
Inhibition of HIV fusion with multivalent gold nanoparticles
-
Bowman MC, Ballard TE, Ackerson CJ, Feldheim DL, Margolis DM, Melander C: Inhibition of HIV fusion with multivalent gold nanoparticles. J. Am. Chem. Soc. 130(22), 6896-6897 (2008).
-
(2008)
J. Am. Chem. Soc
, vol.130
, Issue.22
, pp. 6896-6897
-
-
Bowman, M.C.1
Ballard, T.E.2
Ackerson, C.J.3
Feldheim, D.L.4
Margolis, D.M.5
Melander, C.6
-
62
-
-
36849042601
-
Rna interference against viruses: Strike and counterstrike
-
Haasnoot J, Westerhout EM, Berkhout B: Rna interference against viruses: strike and counterstrike. Nat. Biotechnol. 25(12), 1435-1443 (2007).
-
(2007)
Nat. Biotechnol
, vol.25
, Issue.12
, pp. 1435-1443
-
-
Haasnoot, J.1
Westerhout, E.M.2
Berkhout, B.3
-
63
-
-
84934441156
-
Lentiviral vector delivery of siRNA and shrna encoding genes into cultured and primary hematopoietic cells
-
Li M, Rossi JJ: Lentiviral vector delivery of siRNA and shrna encoding genes into cultured and primary hematopoietic cells. Methods Mol. Biol. 433, 287-299 (2008).
-
(2008)
Methods Mol. Biol
, vol.433
, pp. 287-299
-
-
Li, M.1
Rossi, J.J.2
-
64
-
-
33645144814
-
Lentiviral-mediated delivery of siRNAs for antiviral therapy
-
Morris K V, Rossi JJ: Lentiviral-mediated delivery of siRNAs for antiviral therapy. Gene Ther. 13(6), 553-558 (2006).
-
(2006)
Gene Ther
, vol.13
, Issue.6
, pp. 553-558
-
-
Morris, K.V.1
Rossi, J.J.2
-
65
-
-
33845668311
-
RNAI in combination with a ribozyme and tar decoy for treatment of HIV infection in hematopoietic cell gene therapy
-
Li M, Li H, Rossi JJ: RNAI in combination with a ribozyme and tar decoy for treatment of HIV infection in hematopoietic cell gene therapy. Ann. NY Acad. Sci. 1082, 172-179 (2006).
-
(2006)
Ann. NY Acad. Sci
, vol.1082
, pp. 172-179
-
-
Li, M.1
Li, H.2
Rossi, J.J.3
-
66
-
-
27744605569
-
Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shrna, anti-ccr5 ribozyme, and a nucleolar-localizing tar decoy
-
Li MJ, Kim J, Li S et al.: Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shrna, anti-ccr5 ribozyme, and a nucleolar-localizing tar decoy. Mol. Ther. 12(5), 900-909 (2005).
-
(2005)
Mol. Ther
, vol.12
, Issue.5
, pp. 900-909
-
-
Li, M.J.1
Kim, J.2
Li, S.3
-
67
-
-
23044517213
-
Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV
-
Lee SK, Dykxhoorn DM, Kumar P et al.: Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV. Blood 106(3), 818-826 (2005).
-
(2005)
Blood
, vol.106
, Issue.3
, pp. 818-826
-
-
Lee, S.K.1
Dykxhoorn, D.M.2
Kumar, P.3
-
68
-
-
26644432531
-
Lentiviral-mediated delivery of combined HIV-1 decoy tar and VIF siRNA as a single rna molecule that cleaves to inhibit HIV-1 in transduced cells
-
Barnor JS, Miyano-Kurosaki N, Yamaguchi K, Abumi Y, Ishikawa K, Yamamoto N: Lentiviral-mediated delivery of combined HIV-1 decoy tar and VIF siRNA as a single rna molecule that cleaves to inhibit HIV-1 in transduced cells. Nucleosides Nucleotides Nucleic Acids 24(5-7), 431-434 (2005).
-
(2005)
Nucleosides Nucleotides Nucleic Acids
, vol.24
, Issue.5-7
, pp. 431-434
-
-
Barnor, J.S.1
Miyano-Kurosaki, N.2
Yamaguchi, K.3
Abumi, Y.4
Ishikawa, K.5
Yamamoto, N.6
-
70
-
-
64549134676
-
Nonviral vectors for gene delivery
-
Mintzer MA, Simanek EE: Nonviral vectors for gene delivery. Chem. Rev. 109(2), 259-302 (2009).
-
(2009)
Chem. Rev
, vol.109
, Issue.2
, pp. 259-302
-
-
Mintzer, M.A.1
Simanek, E.E.2
-
71
-
-
70349991426
-
Nanotechnology approaches for gene transfer
-
Lundin KE, Simonson OE, Moreno PM et al.: Nanotechnology approaches for gene transfer. Genetica 137(1), 47-56 (2009).
-
(2009)
Genetica
, vol.137
, Issue.1
, pp. 47-56
-
-
Lundin, K.E.1
Simonson, O.E.2
Moreno, P.M.3
-
72
-
-
34247855110
-
Nonviral gene delivery: What we know and what is next
-
Gao X, Kim KS, Liu DX: Nonviral gene delivery: What we know and what is next. AAPS J. 9(1), E92-E104 (2007).
-
(2007)
AAPS J
, vol.9
, Issue.1
-
-
Gao, X.1
Kim, K.S.2
Liu, D.X.3
-
73
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
-
DOI 10.1038/35888
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC: Potent and specifc genetic interference by double-stranded RNA in caenorhabditis elegans. Nature 391(6669), 806-811 (1998). (Pubitemid 28099681)
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
75
-
-
66149132733
-
Towards a durable rnai gene therapy for HIV-AIDS
-
Berkhout B, ter Brake O: Towards a durable rnai gene therapy for HIV-AIDS. Expert Opin. Biol. Ther. 9(2), 161-170 (2009).
-
(2009)
Expert Opin. Biol. Ther
, vol.9
, Issue.2
, pp. 161-170
-
-
Berkhout, B.1
Ter Brake, O.2
-
76
-
-
67249128859
-
The frst targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: From concept to clinic
-
Davis ME: The frst targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: From concept to clinic. Mol. Pharm. 6(3), 659-668 (2009).
-
(2009)
Mol. Pharm
, vol.6
, Issue.3
, pp. 659-668
-
-
Davis, M.E.1
-
77
-
-
67149093390
-
Effcient siRNA delivery into primary cells by a peptide transduction domain-dsrna binding domain fusion protein
-
Eguchi A, Meade BR, Chang YC et al.: Effcient siRNA delivery into primary cells by a peptide transduction domain-dsrna binding domain fusion protein. Nat. Biotechnol. 27(6), 567-571 (2009).
-
(2009)
Nat. Biotechnol
, vol.27
, Issue.6
, pp. 567-571
-
-
Eguchi, A.1
Meade, B.R.2
Chang, Y.C.3
-
78
-
-
23844474160
-
Antibody mediated in vivo delivery of small interfering rnas via cell-surface receptors
-
Song E, Zhu P, Lee SK et al.: Antibody mediated in vivo delivery of small interfering rnas via cell-surface receptors. Nat. Biotechnol. 23(6), 709-717 (2005).
-
(2005)
Nat. Biotechnol
, vol.23
, Issue.6
, pp. 709-717
-
-
Song, E.1
Zhu, P.2
Lee, S.K.3
-
79
-
-
34247582332
-
Sirna delivery into human t cells and primary cells with carbon-nanotube transporters
-
Liu Z, Winters M, Holodniy M, Dai H: Sirna delivery into human t cells and primary cells with carbon-nanotube transporters. Angew. Chem. Int. Ed. 46(12), 2023-2027 (2007).
-
(2007)
Angew. Chem. Int. Ed
, vol.46
, Issue.12
, pp. 2023-2027
-
-
Liu, Z.1
Winters, M.2
Holodniy, M.3
Dai, H.4
-
80
-
-
54949157770
-
Characterization of carbosilane dendrimers as effective carriers of siRNA to HIV-infected lymphocytes
-
Weber N, Ortega P, Clemente MI et al.: Characterization of carbosilane dendrimers as effective carriers of siRNA to HIV-infected lymphocytes. J. Control Release 132(1), 55-64 (2008).
-
(2008)
J. Control Release
, vol.132
, Issue.1
, pp. 55-64
-
-
Weber, N.1
Ortega, P.2
Clemente, M.I.3
-
81
-
-
49549117077
-
T cell-specifc siRNA delivery suppresses HIV-1 infection in humanized mice
-
Kumar P, Ban HS, Kim SS et al.: T cell-specifc siRNA delivery suppresses HIV-1 infection in humanized mice. Cell 134(4), 577-586 (2008).
-
(2008)
Cell
, vol.134
, Issue.4
, pp. 577-586
-
-
Kumar, P.1
Ban, H.S.2
Kim, S.S.3
-
82
-
-
34447114618
-
Transvascular delivery of small interfering RNA to the central nervous system
-
Kumar P, Wu HQ, McBride JL et al.: Transvascular delivery of small interfering RNA to the central nervous system. Nature 448(7149), 39-43 (2007).
-
(2007)
Nature
, vol.448
, Issue.7149
, pp. 39-43
-
-
Kumar, P.1
Wu, H.Q.2
McBride, J.L.3
-
84
-
-
67651148096
-
Immunotherapies in HIV-1 infection
-
Pett SL: Immunotherapies in HIV-1 infection. Curr. Opin. HIV AIDS 4(3), 188-193 (2009).
-
(2009)
Curr. Opin. HIV AIDS
, vol.4
, Issue.3
, pp. 188-193
-
-
Pett, S.L.1
-
85
-
-
0036182416
-
Immunologic control of HIV-1
-
Gandhi RT, Walker BD: Immunologic control of HIV-1. Ann. Rev. Med. 53, 149-172 (2002).
-
(2002)
Ann. Rev. Med
, vol.53
, pp. 149-172
-
-
Gandhi, R.T.1
Walker, B.D.2
-
86
-
-
34548034889
-
Building an HIV-proof immune system
-
Cohen J: Building an HIV-proof immune system. Science 317(5838), 612-614 (2007).
-
(2007)
Science
, vol.317
, Issue.5838
, pp. 612-614
-
-
Cohen, J.1
-
87
-
-
57449090632
-
Dendritic cell-based human immunodefciency virus vaccine
-
Rinaldo CR: Dendritic cell-based human immunodefciency virus vaccine. J. Intern. Med. 265(1), 138-158 (2009).
-
(2009)
J. Intern. Med
, vol.265
, Issue.1
, pp. 138-158
-
-
Rinaldo, C.R.1
-
89
-
-
0036518287
-
Mouse and human dendritic cell subtypes
-
Shortman K, Liu YJ: Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2(3), 151-161 (2002).
-
(2002)
Nat. Rev. Immunol
, vol.2
, Issue.3
, pp. 151-161
-
-
Shortman, K.1
Liu, Y.J.2
-
91
-
-
34047189908
-
Safety and tolerability of recombinant modifed vaccinia virus ankara expressing an HIV-1 gag/multiepitope immunogen (MVA.HIVA) in HIV-1-infected persons receiving combination antiretroviral therapy
-
Dorrell L, Williams P, Suttill A et al.: Safety and tolerability of recombinant modifed vaccinia virus ankara expressing an HIV-1 gag/multiepitope immunogen (MVA.HIVA) in HIV-1-infected persons receiving combination antiretroviral therapy. Vaccine 25(17), 3277-3283 (2007).
-
(2007)
Vaccine
, vol.25
, Issue.17
, pp. 3277-3283
-
-
Dorrell, L.1
Williams, P.2
Suttill, A.3
-
92
-
-
70349299844
-
A randomized therapeutic vaccine trial of canarypox-HIV-pulsed dendritic cells vs, Canarypox-HIV alone in HIV-1-infected patients on antiretroviral therapy
-
Gandhi RT, O'Neill D, Bosch RJ et al.: A randomized therapeutic vaccine trial of canarypox-HIV-pulsed dendritic cells vs. Canarypox-HIV alone in HIV-1-infected patients on antiretroviral therapy. Vaccine 27(43), 6088-6094 (2009).
-
(2009)
Vaccine
, vol.27
, Issue.43
, pp. 6088-6094
-
-
Gandhi, R.T.1
O'Neill, D.2
Bosch, R.J.3
-
93
-
-
59649106811
-
Production of a dendritic cell-based vaccine containing inactivated autologous virus for therapy of patients with chronic human immunodefciency virus type 1 infection
-
Whiteside TL, Piazza P, Reiter A et al.: Production of a dendritic cell-based vaccine containing inactivated autologous virus for therapy of patients with chronic human immunodefciency virus type 1 infection. Clin. Vaccine Immunol. 16(2), 233-240 (2009).
-
(2009)
Clin. Vaccine Immunol
, vol.16
, Issue.2
, pp. 233-240
-
-
Whiteside, T.L.1
Piazza, P.2
Reiter, A.3
-
94
-
-
34748886192
-
Dendritic-cell immunotherapy: From ex vivo loading to in vivo targeting
-
Tacken PJ, de Vries IJM, Torensma R, Figdor CG: Dendritic-cell immunotherapy: From ex vivo loading to in vivo targeting. Nat. Rev. Immunol. 7(10), 790-802 (2007).
-
(2007)
Nat. Rev. Immunol
, vol.7
, Issue.10
, pp. 790-802
-
-
Tacken, P.J.1
De Vries, I.J.M.2
Torensma, R.3
Figdor, C.G.4
-
95
-
-
33646480406
-
In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfde) nanoparticles
-
Reddy ST, Rehor A, Schmoekel HG, Hubbell JA, Swartz MA: In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfde) nanoparticles. J. Control Release 112(1), 26-34 (2006).
-
(2006)
J. Control Release
, vol.112
, Issue.1
, pp. 26-34
-
-
Reddy, S.T.1
Rehor, A.2
Schmoekel, H.G.3
Hubbell, J.A.4
Swartz, M.A.5
-
96
-
-
46749110694
-
Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy
-
Hori Y, Winans AM, Huang CC, Horrigan EM, Irvine DJ: Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy. Biomaterials 29(27), 3671-3682 (2008).
-
(2008)
Biomaterials
, vol.29
, Issue.27
, pp. 3671-3682
-
-
Hori, Y.1
Winans, A.M.2
Huang, C.C.3
Horrigan, E.M.4
Irvine, D.J.5
-
97
-
-
2942562255
-
Characterization of poly(d,l-lactic-co-glycolic acid) based nanoparticulate system for enhanced delivery of antigens to dendritic cells
-
Elamanchili P, Diwan M, Cao M, Samuel J: Characterization of poly(d,l-lactic-co-glycolic acid) based nanoparticulate system for enhanced delivery of antigens to dendritic cells. Vaccine 22(19), 2406-2412 (2004).
-
(2004)
Vaccine
, vol.22
, Issue.19
, pp. 2406-2412
-
-
Elamanchili, P.1
Diwan, M.2
Cao, M.3
Samuel, J.4
-
98
-
-
67749142116
-
Dendritic cells loaded with HIV-1 p24 proteins adsorbed on surfactant-free anionic pla nanoparticles induce enhanced cellular immune responses against HIV-1 after vaccination
-
Aline F, Brand D, Pierre J et al.: Dendritic cells loaded with HIV-1 p24 proteins adsorbed on surfactant-free anionic pla nanoparticles induce enhanced cellular immune responses against HIV-1 after vaccination. Vaccine 27(38), 5284-5291 (2009).
-
(2009)
Vaccine
, vol.27
, Issue.38
, pp. 5284-5291
-
-
Aline, F.1
Brand, D.2
Pierre, J.3
-
99
-
-
34547668503
-
Nanochemistry-based immunotherapy for HIV-1
-
Lori F, Calarota SA, Lisziewicz J: Nanochemistry-based immunotherapy for HIV-1. Curr. Med. Chem. 14(18), 1911-1919 (2007).
-
(2007)
Curr. Med. Chem
, vol.14
, Issue.18
, pp. 1911-1919
-
-
Lori, F.1
Calarota, S.A.2
Lisziewicz, J.3
-
100
-
-
67449088277
-
Aids vaccine research and advocacy: An update
-
Bass E, Feuer C, Warren M: Aids vaccine research and advocacy: An update. BETA 21(2), 24-30 (2009).
-
(2009)
BETA
, vol.21
, Issue.2
, pp. 24-30
-
-
Bass, E.1
Feuer, C.2
Warren, M.3
-
101
-
-
44849096408
-
Vaccine failure is not a 'crisis' for HIV research
-
Jefferys R: Vaccine failure is not a 'crisis' for HIV research. Nature 453(7196), 719-720 (2008).
-
(2008)
Nature
, vol.453
, Issue.7196
, pp. 719-720
-
-
Jefferys, R.1
-
102
-
-
53349160053
-
Challenges in the development of an HIV-1 vaccine
-
Barouch DH: Challenges in the development of an HIV-1 vaccine. Nature 455(7213), 613-619 (2008).
-
(2008)
Nature
, vol.455
, Issue.7213
, pp. 613-619
-
-
Barouch, D.H.1
-
103
-
-
0036214292
-
Antigen presentation and t cell stimulation by dendritic cells
-
Guermonprez P, Valladeau J, Zitvogel L, Thery C, Amigorena S: Antigen presentation and t cell stimulation by dendritic cells. Ann. Rev. Immunol. 20, 621-667 (2002).
-
(2002)
Ann. Rev. Immunol
, vol.20
, pp. 621-667
-
-
Guermonprez, P.1
Valladeau, J.2
Zitvogel, L.3
Thery, C.4
Amigorena, S.5
-
104
-
-
17644370329
-
Cell biology of antigen processing in vitro and in vivo
-
Trombetta ES, Mellman I: Cell biology of antigen processing in vitro and in vivo. Ann. Rev. Immunol. 23, 975-1028 (2005).
-
(2005)
Ann. Rev. Immunol
, vol.23
, pp. 975-1028
-
-
Trombetta, E.S.1
Mellman, I.2
-
106
-
-
45149125881
-
Design opportunities for actively targeted nanoparticle vaccines
-
Fahmy TM, Demento SL, Caplan MJ, Mellman I, Saltzman WM: Design opportunities for actively targeted nanoparticle vaccines. Nanomed. 3(3), 343-355 (2008).
-
(2008)
Nanomed
, vol.3
, Issue.3
, pp. 343-355
-
-
Fahmy, T.M.1
Demento, S.L.2
Caplan, M.J.3
Mellman, I.4
Saltzman, W.M.5
-
108
-
-
0037223094
-
HIV mucosal vaccine: Nasal immunization with gp160-encapsulated hemagglutinating virus of japan-liposome induces antigen-specifc ctls and neutralizing antibody responses
-
Sakaue G, Hiroi T, Nakagawa Y et al.: HIV mucosal vaccine: Nasal immunization with gp160-encapsulated hemagglutinating virus of japan-liposome induces antigen-specifc ctls and neutralizing antibody responses. J. Immunol. 170(1), 495-502 (2003).
-
(2003)
J. Immunol
, vol.170
, Issue.1
, pp. 495-502
-
-
Sakaue, G.1
Hiroi, T.2
Nakagawa, Y.3
-
109
-
-
33646157934
-
Adjuvanticity of stealth liposomes on the immunogenicity of synthetic gp41 epitope of HIV-1
-
Singh SK, Bisen PS: Adjuvanticity of stealth liposomes on the immunogenicity of synthetic gp41 epitope of HIV-1. Vaccine 24(19), 4161-4166 (2006).
-
(2006)
Vaccine
, vol.24
, Issue.19
, pp. 4161-4166
-
-
Singh, S.K.1
Bisen, P.S.2
-
110
-
-
36248987265
-
One step membrane incorporation of viral antigens as a vaccine candidate against HIV
-
Wagner A, Stiegler G, Vorauer-Uhl K et al.: One step membrane incorporation of viral antigens as a vaccine candidate against HIV. J. Liposome Res. 17(3-4), 139-154 (2007).
-
(2007)
J. Liposome Res
, vol.17
, Issue.3-4
, pp. 139-154
-
-
Wagner, A.1
Stiegler, G.2
Vorauer-Uhl, K.3
-
111
-
-
70450228599
-
All-trans retinoic acid potentiates the antibody response in mice to a lipopeptide antigen adjuvanted with liposomal lipid a
-
Watson DS, Huang Z, Szoka FC Jr: All-trans retinoic acid potentiates the antibody response in mice to a lipopeptide antigen adjuvanted with liposomal lipid a. Immunol. Cell Biol. (2009).
-
(2009)
Immunol. Cell Biol.
-
-
Watson, D.S.1
Huang, Z.2
Szoka Jr, F.C.3
-
112
-
-
33845207660
-
Progress and obstacles in the development of an AIDS vaccine
-
Letvin NL: Progress and obstacles in the development of an AIDS vaccine. Nat. Rev. Immunol. 6(12), 930-939 (2006).
-
(2006)
Nat. Rev. Immunol
, vol.6
, Issue.12
, pp. 930-939
-
-
Letvin, N.L.1
-
113
-
-
1542317452
-
HIV vaccine design and the neutralizing antibody problem
-
Burton DR, Desrosiers RC, Doms RW et al.: HIV vaccine design and the neutralizing antibody problem. Nat. Immunol. 5(3), 233-236 (2004).
-
(2004)
Nat. Immunol
, vol.5
, Issue.3
, pp. 233-236
-
-
Burton, D.R.1
Desrosiers, R.C.2
Doms, R.W.3
-
115
-
-
67549149326
-
Enhanced in vivo immunogenicity of SIV vaccine candidates with cationic liposome-DNA complexes in a rhesus macaque pilot study
-
Fairman J, Moore J, Lemieux M et al.: Enhanced in vivo immunogenicity of SIV vaccine candidates with cationic liposome-DNA complexes in a rhesus macaque pilot study. Hum. Vaccin. 5(2), (2008).
-
(2008)
Hum. Vaccin
, vol.5
, pp. 2
-
-
Fairman, J.1
Moore, J.2
Lemieux, M.3
-
116
-
-
0029177443
-
Mf59. Design and evaluation of a safe and potent adjuvant for human vaccines
-
Ott G, Barchfeld GL, Chernoff D, Radhakrishnan R, van Hoogevest P, Van Nest G: Mf59. Design and evaluation of a safe and potent adjuvant for human vaccines. Pharm. Biotechnol. 6, 277-296 (1995).
-
(1995)
Pharm. Biotechnol
, vol.6
, pp. 277-296
-
-
Ott, G.1
Barchfeld, G.L.2
Chernoff, D.3
Radhakrishnan, R.4
Van Hoogevest, P.5
Van Nest, G.6
-
117
-
-
16344384382
-
Lipid based particulate formulations for the delivery of antigen
-
Copland MJ, Rades T, Davies NM, Baird MA: Lipid based particulate formulations for the delivery of antigen. Immunol. Cell. Biol. 83(2), 97-105 (2005).
-
(2005)
Immunol. Cell. Biol
, vol.83
, Issue.2
, pp. 97-105
-
-
Copland, M.J.1
Rades, T.2
Davies, N.M.3
Baird, M.A.4
-
118
-
-
67349269509
-
Mechanism of action of licensed vaccine adjuvants
-
Tritto E, Mosca F, De Gregorio E: Mechanism of action of licensed vaccine adjuvants. Vaccine 27(25-26), 3331-3334 (2009).
-
(2009)
Vaccine
, vol.27
, Issue.25-26
, pp. 3331-3334
-
-
Tritto, E.1
Mosca, F.2
De Gregorio, E.3
-
119
-
-
2342520612
-
Immunogenicity of HIV-1 env and gag in baboons using a DNA prime/protein boost regimen
-
Leung L, Srivastava IK, Kan E et al.: Immunogenicity of HIV-1 env and gag in baboons using a DNA prime/protein boost regimen. AIDS 18(7), 991-1001 (2004).
-
(2004)
AIDS
, vol.18
, Issue.7
, pp. 991-1001
-
-
Leung, L.1
Srivastava, I.K.2
Kan, E.3
-
120
-
-
34548590355
-
Candidate HIV-1 gp140dv2, gag and tat vaccines protect against experimental HIV-1/MULV challenge
-
Brave A, Hinkula J, Cafaro A et al.: Candidate HIV-1 gp140dv2, gag and tat vaccines protect against experimental HIV-1/MULV challenge. Vaccine 25(39-40), 6882-6890 (2007).
-
(2007)
Vaccine
, vol.25
, Issue.39-40
, pp. 6882-6890
-
-
Brave, A.1
Hinkula, J.2
Cafaro, A.3
-
121
-
-
63549137349
-
Neutralizing antibody responses to subtype b and c adjuvanted HIV envelope protein vaccination in rabbits
-
Burke B, Gomez-Roman VR, Lian Y et al.: Neutralizing antibody responses to subtype b and c adjuvanted HIV envelope protein vaccination in rabbits. Virology 387(1), 147-156 (2009).
-
(2009)
Virology
, vol.387
, Issue.1
, pp. 147-156
-
-
Burke, B.1
Gomez-Roman, V.R.2
Lian, Y.3
-
122
-
-
39549118132
-
Nasal immunization with a recombinant HIV gp120 and nanoemulsion adjuvant produces th1 polarized responses and neutralizing antibodies to primary HIV type 1 isolates
-
Bielinska AU, Janczak KW, Landers JJ, Markovitz DM, Montefori DC, Baker JR Jr: Nasal immunization with a recombinant HIV gp120 and nanoemulsion adjuvant produces th1 polarized responses and neutralizing antibodies to primary HIV type 1 isolates. AIDS Res. Hum. Retroviruses 24(2), 271-281 (2008).
-
(2008)
AIDS Res. Hum. Retroviruses
, vol.24
, Issue.2
, pp. 271-281
-
-
Bielinska, A.U.1
Janczak, K.W.2
Landers, J.J.3
Markovitz, D.M.4
Montefori, D.C.5
Baker Jr, J.R.6
-
123
-
-
33646482240
-
Surfactant-free anionic pla nanoparticles coated with HIV-1 p24 protein induced enhanced cellular and humoral immune responses in various animal models
-
Ataman-Onal Y, Munier S, Ganee A et al.: Surfactant-free anionic pla nanoparticles coated with HIV-1 p24 protein induced enhanced cellular and humoral immune responses in various animal models. J. Control Release 112(2), 175-185 (2006).
-
(2006)
J. Control Release
, vol.112
, Issue.2
, pp. 175-185
-
-
Ataman-Onal, Y.1
Munier, S.2
Ganee, A.3
-
124
-
-
33748927941
-
Coadsorption of HIV-1 p24 and gp120 proteins to surfactant-free anionic pla nanoparticles preserves antigenicity and immunogenicity
-
Lamalle-Bernard D, Munier S, Compagnon C et al.: Coadsorption of HIV-1 p24 and gp120 proteins to surfactant-free anionic pla nanoparticles preserves antigenicity and immunogenicity. J. Control Release 115(1), 57-67 (2006).
-
(2006)
J. Control Release
, vol.115
, Issue.1
, pp. 57-67
-
-
Lamalle-Bernard, D.1
Munier, S.2
Compagnon, C.3
-
125
-
-
34948892906
-
Formulation of HIV-1 tat and p24 antigens by pla nanoparticles or mf59 impacts the breadth, but not the magnitude, of serum and faecal antibody responses in rabbits
-
Guillon C, Mayol K, Terrat C et al.: Formulation of HIV-1 tat and p24 antigens by pla nanoparticles or mf59 impacts the breadth, but not the magnitude, of serum and faecal antibody responses in rabbits. Vaccine 25(43), 7491-7501 (2007).
-
(2007)
Vaccine
, vol.25
, Issue.43
, pp. 7491-7501
-
-
Guillon, C.1
Mayol, K.2
Terrat, C.3
-
126
-
-
2542505511
-
Induction of HIV-specifc antibody response and protection against vaginal sHIV transmission by intranasal immunization with inactivated sHIV-capturing nanospheres in macaques
-
Miyake A, Akagi T, Enose Y et al.: Induction of HIV-specifc antibody response and protection against vaginal sHIV transmission by intranasal immunization with inactivated sHIV-capturing nanospheres in macaques. J. Med. Virol. 73(3), 368-377 (2004).
-
(2004)
J. Med. Virol
, vol.73
, Issue.3
, pp. 368-377
-
-
Miyake, A.1
Akagi, T.2
Enose, Y.3
-
127
-
-
20144389002
-
Induction of dendritic cell-mediated immune responses against HIV-1 by antigen-capturing nanospheres in mice
-
Kawamura M, Wang X, Uto T et al.: Induction of dendritic cell-mediated immune responses against HIV-1 by antigen-capturing nanospheres in mice. J. Med. Virol. 76(1), 7-15 (2005).
-
(2005)
J. Med. Virol
, vol.76
, Issue.1
, pp. 7-15
-
-
Kawamura, M.1
Wang, X.2
Uto, T.3
-
128
-
-
34248332505
-
Protein direct delivery to dendritic cells using nanoparticles based on amphiphilic poly(amino acid) derivatives
-
Akagi T, Wang X, Uto T, Baba M, Akashi M: Protein direct delivery to dendritic cells using nanoparticles based on amphiphilic poly(amino acid) derivatives. Biomaterials 28(23), 3427-3436 (2007).
-
(2007)
Biomaterials
, vol.28
, Issue.23
, pp. 3427-3436
-
-
Akagi, T.1
Wang, X.2
Uto, T.3
Baba, M.4
Akashi, M.5
-
129
-
-
35348909614
-
+ T-cell responses by novel biodegradable nanoparticles carrying human immunodefciency virus type 1 gp120
-
+ T-cell responses by novel biodegradable nanoparticles carrying human immunodefciency virus type 1 gp120. J. Virol. 81(18), 10009-10016 (2007).
-
(2007)
J. Virol
, vol.81
, Issue.18
, pp. 10009-10016
-
-
Wang, X.1
Uto, T.2
Akagi, T.3
Akashi, M.4
Baba, M.5
-
130
-
-
36849058878
-
Poly(gamma-glutamic acid) nanoparticles as an effcient antigen delivery and adjuvant system: Potential for an AIDS vaccine
-
Wang X, Uto T, Akagi T, Akashi M, Baba M: Poly(gamma-glutamic acid) nanoparticles as an effcient antigen delivery and adjuvant system: Potential for an AIDS vaccine. J. Med. Virol. 80(1), 11-19 (2008).
-
(2008)
J. Med. Virol
, vol.80
, Issue.1
, pp. 11-19
-
-
Wang, X.1
Uto, T.2
Akagi, T.3
Akashi, M.4
Baba, M.5
-
131
-
-
2342434865
-
Population-level HIV declines and behavioral risk avoidance in uganda
-
Stoneburner RL, Low-Beer D: Population-level HIV declines and behavioral risk avoidance in uganda. Science 304(5671), 714-718 (2004).
-
(2004)
Science
, vol.304
, Issue.5671
, pp. 714-718
-
-
Stoneburner, R.L.1
Low-Beer, D.2
-
132
-
-
65549159648
-
Vaginal drug delivery systems for HIV prevention
-
Rohan LC, Sassi AB: Vaginal drug delivery systems for HIV prevention. AAPS J. 11(1), 78-87 (2009).
-
(2009)
AAPS J
, vol.11
, Issue.1
, pp. 78-87
-
-
Rohan, L.C.1
Sassi, A.B.2
-
133
-
-
64049119714
-
Microbicides: An emerging science of HIV-1 prevention in women-15th conference on retroviruses and opportunistic infections, boston, USA, 3-6 February 2008
-
Saidi H: Microbicides: An emerging science of HIV-1 prevention in women-15th conference on retroviruses and opportunistic infections, boston, USA, 3-6 February 2008. Rev. Med. Virol. 19(2), 69-76 (2009).
-
(2009)
Rev. Med. Virol
, vol.19
, Issue.2
, pp. 69-76
-
-
Saidi, H.1
-
134
-
-
33745504777
-
Gels as vaginal drug delivery systems
-
das Neves J, Bahia MF: Gels as vaginal drug delivery systems. Int. J. Pharm. 318(1-2), 1-14 (2006).
-
(2006)
Int. J. Pharm
, vol.318
, Issue.1-2
, pp. 1-14
-
-
Das Neves, J.1
Bahia, M.F.2
-
135
-
-
39649091895
-
Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission
-
Klasse PJ, Shattock R, Moore JP: Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission. Ann. Rev. Med. 59, 455-471 (2008).
-
(2008)
Ann. Rev. Med
, vol.59
, pp. 455-471
-
-
Klasse, P.J.1
Shattock, R.2
Moore, J.P.3
-
136
-
-
38949198100
-
Vivagel (spl7013 gel): A candidate dendrimer-microbicide for the prevention of HIV and hsv infection
-
Rupp R, Rosenthal SL, Stanberry LR: Vivagel (spl7013 gel): A candidate dendrimer-microbicide for the prevention of HIV and hsv infection. Int. J. Nanomedicine 2(4), 561-566 (2007).
-
(2007)
Int. J. Nanomedicine
, vol.2
, Issue.4
, pp. 561-566
-
-
Rupp, R.1
Rosenthal, S.L.2
Stanberry, L.R.3
-
137
-
-
23944434447
-
Dendrimers as drugs: Discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention
-
McCarthy TD, Karellas P, Henderson SA et al.: Dendrimers as drugs: Discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention. Mol. Pharm. 2(4), 312-318 (2005).
-
(2005)
Mol. Pharm
, vol.2
, Issue.4
, pp. 312-318
-
-
McCarthy, T.D.1
Karellas, P.2
Henderson, S.A.3
-
138
-
-
16444385352
-
Spl7013 gel as a topical microbicide for prevention of vaginal transmission of sHIV89.6p in macaques
-
Jiang YH, Emau P, Cairns JS et al.: Spl7013 gel as a topical microbicide for prevention of vaginal transmission of sHIV89.6p in macaques. AIDS Res. Hum. Retroviruses 21(3), 207-213 (2005).
-
(2005)
AIDS Res. Hum. Retroviruses
, vol.21
, Issue.3
, pp. 207-213
-
-
Jiang, Y.H.1
Emau, P.2
Cairns, J.S.3
-
139
-
-
60149105478
-
Targeted delivery of psc-rantes for HIV-1 prevention using biodegradable nanoparticles
-
Ham AS, Cost MR, Sassi AB, Dezzutti CS, Rohan LC: Targeted delivery of psc-rantes for HIV-1 prevention using biodegradable nanoparticles. Pharm. Res. 26(3), 502-511 (2009).
-
(2009)
Pharm. Res
, vol.26
, Issue.3
, pp. 502-511
-
-
Ham, A.S.1
Cost, M.R.2
Sassi, A.B.3
Dezzutti, C.S.4
Rohan, L.C.5
-
140
-
-
5644247983
-
Prevention of vaginal sHIV transmission in rhesus macaques through inhibition of ccr5
-
Lederman MM, Veazey RS, Offord R et al.: Prevention of vaginal sHIV transmission in rhesus macaques through inhibition of ccr5. Science 306(5695), 485-487 (2004).
-
(2004)
Science
, vol.306
, Issue.5695
, pp. 485-487
-
-
Lederman, M.M.1
Veazey, R.S.2
Offord, R.3
-
141
-
-
30144434185
-
An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection
-
Palliser D, Chowdhury D, Wang QY et al.: An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection. Nature 439(7072), 89-94 (2006).
-
(2006)
Nature
, vol.439
, Issue.7072
, pp. 89-94
-
-
Palliser, D.1
Chowdhury, D.2
Wang, Q.Y.3
-
142
-
-
33749985477
-
Topical antiviral siRNA: A practical siRNA microbicide?
-
Rossi JJ: Topical antiviral siRNA: A practical siRNA microbicide? Gene Ther. 13(21), 1493-1494 (2006).
-
(2006)
Gene Ther
, vol.13
, Issue.21
, pp. 1493-1494
-
-
Rossi, J.J.1
-
143
-
-
58249094519
-
Durable protection from herpes simplex virus-2 transmission following intravaginal application of siRNAs targeting both a viral and host gene
-
Wu Y, Navarro F, Lal A et al.: Durable protection from herpes simplex virus-2 transmission following intravaginal application of siRNAs targeting both a viral and host gene. Cell. Host Microbe 5(1), 84-94 (2009).
-
(2009)
Cell. Host Microbe
, vol.5
, Issue.1
, pp. 84-94
-
-
Wu, Y.1
Navarro, F.2
Lal, A.3
-
144
-
-
66249083866
-
Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering
-
Woodrow KA, Cu Y, Booth CJ, Saucier-Sawyer JK, Wood MJ, Saltzman WM: Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA. Nat. Mater. 8(6), 526-533 (2009).
-
(2009)
RNA. Nat. Mater
, vol.8
, Issue.6
, pp. 526-533
-
-
Woodrow, K.A.1
Cu, Y.2
Booth, C.J.3
Saucier-Sawyer, J.K.4
Wood, M.J.5
Saltzman, W.M.6
-
145
-
-
51849084844
-
Self-assembled lipid-polymer hybrid nanoparticles: A robust drug delivery platform
-
Zhang LF, Chan JM, Gu FX et al.: Self-assembled lipid-polymer hybrid nanoparticles: A robust drug delivery platform. ACS Nano 2(8), 1696-1702 (2008).
-
(2008)
ACS Nano
, vol.2
, Issue.8
, pp. 1696-1702
-
-
Zhang, L.F.1
Chan, J.M.2
Gu, F.X.3
-
146
-
-
42349106952
-
Co-delivery of hydrophobic and hydrophilic drugs from nanoparticle-aptamer bioconjugates
-
Zhang LF, Radovic-Moreno AF, Alexis F et al.: Co-delivery of hydrophobic and hydrophilic drugs from nanoparticle-aptamer bioconjugates. Chem. Med. Chem. 2(9), 1268-1271 (2007).
-
(2007)
Chem. Med. Chem
, vol.2
, Issue.9
, pp. 1268-1271
-
-
Zhang, L.F.1
Radovic-Moreno, A.F.2
Alexis, F.3
-
147
-
-
33749983751
-
Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer
-
Wang Y, Gao SJ, Ye WH, Yoon HS, Yang YY: Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer. Nat. Mater. 5(10), 791-796 (2006).
-
(2006)
Nat. Mater
, vol.5
, Issue.10
, pp. 791-796
-
-
Wang, Y.1
Gao, S.J.2
Ye, W.H.3
Yoon, H.S.4
Yang, Y.Y.5
-
148
-
-
57649124218
-
The co-delivery of paclitaxel and herceptin using cationic micellar nanoparticles
-
Lee ALZ, Wang Y, Cheng HY, Pervaiz S, Yang YY: The co-delivery of paclitaxel and herceptin using cationic micellar nanoparticles. Biomaterials 30(5), 919-927 (2009).
-
(2009)
Biomaterials
, vol.30
, Issue.5
, pp. 919-927
-
-
Lee, A.L.Z.1
Wang, Y.2
Cheng, H.Y.3
Pervaiz, S.4
Yang, Y.Y.5
-
149
-
-
38849090544
-
Can the new humanized mouse model give HIV research a boost
-
Shacklett BL: Can the new humanized mouse model give HIV research a boost. PLoS Med. 5(1), e13 (2008).
-
(2008)
PLoS Med
, vol.5
, Issue.1
-
-
Shacklett, B.L.1
-
150
-
-
33846630040
-
Humanized mice in translational biomedical research
-
Shultz LD, Ishikawa F, Greiner DL: Humanized mice in translational biomedical research. Nat. Rev. Immunol. 7(2), 118-130 (2007).
-
(2007)
Nat. Rev. Immunol
, vol.7
, Issue.2
, pp. 118-130
-
-
Shultz, L.D.1
Ishikawa, F.2
Greiner, D.L.3
-
151
-
-
39049124118
-
Nanoparticle strategies for the oral delivery of insulin
-
Damge C, Reis CP, Maincent P: Nanoparticle strategies for the oral delivery of insulin. Expert Opin. Drug Del. 5(1), 45-68 (2008).
-
(2008)
Expert Opin. Drug Del
, vol.5
, Issue.1
, pp. 45-68
-
-
Damge, C.1
Reis, C.P.2
Maincent, P.3
-
152
-
-
60149111908
-
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
-
Lai SK, Wang YY, Hanes J: Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Adv. Drug Del. Rev. 61(2), 158-171 (2009).
-
(2009)
Adv. Drug Del. Rev
, vol.61
, Issue.2
, pp. 158-171
-
-
Lai, S.K.1
Wang, Y.Y.2
Hanes, J.3
-
153
-
-
73349140554
-
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier
-
Tang BC, Dawson M, Lai SK et al.: Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proc. Natl Acad. Sci. USA 106(46), 19268-19273 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, Issue.46
, pp. 19268-19273
-
-
Tang, B.C.1
Dawson, M.2
Lai, S.K.3
-
154
-
-
75649105391
-
Amphiphilic poly{[a-maleic anhydride-omega-methoxy-poly(ethylene glycol)]-co-(ethyl cyanoacrylate)} graft copolymer nanoparticles as carriers for transdermal drug delivery
-
Xing JF, Deng LD, Li J, Dong AJ: Amphiphilic poly{[a-maleic anhydride-omega-methoxy-poly(ethylene glycol)]-co-(ethyl cyanoacrylate)} graft copolymer nanoparticles as carriers for transdermal drug delivery. Int. J. Nanomedicine 4, 227-232 (2009).
-
(2009)
Int. J. Nanomedicine
, vol.4
, pp. 227-232
-
-
Xing, J.F.1
Deng, L.D.2
Li, J.3
Dong, A.J.4
|