Induction of dendritic cell-mediated immune responses against HIV-1 by antigen-capturing nanospheres in mice

Journal of Medical Virology

Volumn 76, Issue 1, 2005, Pages 7-15

  Kawamura, Masaki ^a,f   Wang, Xin ^a,e   Uto, Tomofumi ^a,e   Sato, Katsuaki ^a,e,g   Ueno, Masamichi ^b   Akagi, Takami ^b,d,h   Hiraishi, Katsuya ^b   Matsuyama, Takami ^a   Akashi, Mitsuru ^c,d,e   Baba, Masanori ^a,e  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b Japan Immunoresearch Institute   (Japan)

^c KAGOSHIMA UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^f UNIVERSITY OF YAMANASHI   (Japan)

^g RIKEN Center for Integrative Medical Sciences   (Japan)

^h NONE

Author keywords

CTL; Dendritic cells; HIV 1; Nanospheres; Vaccine

Indexed keywords

CONCANAVALIN A; CYTOCHALASIN D; FLUORESCEIN ISOTHIOCYANATE; NANOPARTICLE;

ANIMAL CELL; ANTIBODY DETECTION; ANTIGEN DETECTION; ANTIGEN SPECIFICITY; ARTICLE; BINDING SITE; CELL SPECIFICITY; CONTROLLED STUDY; CYTOSKELETON; DENDRITIC CELL; DRUG POTENCY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMORAL IMMUNITY; IMMUNE RESPONSE; LUNG ALVEOLUS CELL; MOUSE; NONHUMAN; VACCINE PRODUCTION; VIRUS TRANSMISSION;

ADMINISTRATION, INTRANASAL; AIDS VACCINES; ANIMALS; ANTIBODY SPECIFICITY; BONE MARROW; COCULTURE TECHNIQUES; CONCANAVALIN A; DENDRITIC CELLS; FEMALE; FLUORESCEIN-5-ISOTHIOCYANATE; GENITALIA, FEMALE; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HIV-1; IMMUNIZATION; INTERFERON TYPE II; LUNG; MICE; MICE, INBRED BALB C; NANOTUBES; SPLEEN; T-LYMPHOCYTES, CYTOTOXIC;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 20144389002     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmv.20317     Document Type: Article

References (40)

1. Akagi T, Kawamura M, Ueno M, Hiraishi K, Adachi M, Serizawa T, Akashi M, Baba M. 2003. Mucosal immunization with inactivated HIV-1-capturing nanospheres induces a significant HIV-1-specific vaginal antibody response in mice. J Med Virol 69:163-172.
2. Akashi M, Niikawa T, Serizawa T, Hayakawa T, Baba M. 1998. Capture of HIV-1 gp120 and virions by lectin-immobilized polystyrene nanospheres. Bioconjug Chem 9:50-53.
3. Akbari O, DeKruyff RH, Umetsu DT. 2001. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat Immunol 2:725-731.
4. Balmelli C, Demotz S, Acha-Orbea H, De Grandi P, Nardelli-Haefliger D. 2002. Trachea, lung, and tracheobronchial lymph nodes are the major sites where antigen-presenting cells are detected after nasal vaccination of mice with human papillomavirus type 16 virus-like particles. J Virol 76:12596-12602.
5. Banchereau J, Briere F, Caux C, Davoust J, Lebecque S, Liu YJ, Pulendran B, Palucka K. 2000. Immunobiology of dendritic cells. Annu Rev Immunol 18:767-811.
6. Belyakov IM, Derby MA, Ahlers JD, Kelsall BL, Earl P, Moss B, Strober W, Berzofsky JA. 1998. Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge. Proc Natl Acad Sci USA 95: 1709-1714.
7. Beyrer C, Artenstein AW, Rugpao S, Stephens H, VanCott TC, Robb ML, Rinkaew M, Birx DL, Khamboonruang C, Zimmerman PA, Nelson KE, Natpratan C, for the Chiang Mai HEPS Working Group. 1999. Epidemiologic and biologic characterization of a cohort of human immunodeficiency virus type 1 highly exposed, persistently seronegative female sex workers in northern Thailand. J Infect Dis 179:59-67.
8. Biragyn A, Belyakov IM, Chow YH, Dimitrov DS, Berzofsky JA, Kwak LW. 2002. DNA vaccines encoding human immunodeficiency virus-1 glycoprotein 120 fusions with proinflammatory chemoattractants induce systemic and mucosal immune responses. Blood 100:1153-1159.
9. Bomsel M, Heyman M, Hocini H, Lagaye S, Belec L, Dupont C, Desgranges C. 1998. Intracellular neutralization of HIV transcytosis across tight epithelial barriers by anti-HIV envelope protein dlgA or IgM. Immunity 9:277-287.
10. Crotty S, Miller CJ, Lohman BL, Neagu MR, Compton L, Lu D, Lu FX, Fritts L, Lifson JD, Andino R. 2001. Protection against simian immunodeficiency virus vaginal challenge by using Sabin poliovirus vectors. J Virol 75:7435-7452.
11. Devito C, Hinkula J, Kaul R, Lopalco L, Bwayo JJ, Plummer F, Clerici M, Broliden K. 2000a. Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate. AIDS 14:1917-1920.
12. Devito C, Broliden K, Kaul R, Svensson L, Johansen K, Kiama P, Kimani J, Lopalco L, Piconi S, Bwayo JJ, Plummer F, Clerici M, Hinkula J. 2000b. Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 transcytosis across human epithelial cells. J Immunol 165:5170-5176.
13. Fuller DH, Rajakumar PA, Wilson LA, Trichel AM, Fuller JT, Shipley T, Wu MS, Weis K, Rinaldo CR, Haynes JR, Murphey-Corb M. 2002. Induction of mucosal protection against primary, heterologous simian immunodeficiency virus by a DNA vaccine. J Virol 76:3309-3317.
14. Golding B, Eller N, Levy L, Beining P, Inman J, Matthews N, Scott DE, Golding H. 2002. Mucosal immunity in mice immunized with HIV-1 peptide conjugated to Brucella abortus. Vaccine 20:1445-1450.
15. Hayakawa T, Kawamura M, Okamoto M, Baba M, Niikawa T, Takehara S, Serizawa T, Akashi M. 1998. Concanavalin A-immobilized polystyrene nanospheres capture HIV-1 virions and gp120: Potential approach towards prevention of viral transmission. J Med Virol 56:327-331.
16. Horner AA, Datta SK, Takabayashi K, Belyakov IM, Hayashi T, Cinman N, Nguyen MD, Van Uden JH, Berzofsky JA, Richman DD, Raz E. 2001. Immunostimulatory DNA-based vaccines elicit multi-faceted immune responses against HIV at systemic and mucosal sites. J Immunol 167:1584-1591.
17. Hu J, Gardner MB, Miller CJ. 2000. Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells. J Virol 74: 6087-6095.
18. Kato H, Bukawa H, Hagiwara E, Xin KQ, Hamajima K, Kawamoto S, Sugiyama M, Sugiyama M, Noda E, Nishizaki M, Okuda K. 2000. Rectal and vaginal immunization with a macromolecular multi-component peptide vaccine candidate for HIV-1 infection induces HIV-specific protective immune responses. Vaccine 18:1151-1160.
19. Kaul R, Trabattoni D, Bwayo JJ, Arienti D, Zagliani A, Mwangi FM, Kariuki C, Ngugi EN, MacDonald KS, Ball TB, Clerici M, Plummer FA. 1999. HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers. AIDS 13:23-29.
20. Kaul R, Plummer FA, Kimani J, Dong T, Kiama P, Rostron T, Njagi E, MacDonald KS, Bwayo JJ, McMichael AJ, Rowland-Jones SL. 2000. HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi. J Immunol 164: 1602-1611.
21. Kawamura M, Naito T, Ueno M, Akagi T, Hiraishi K, Takai I, Makino M, Serizawa T, Sugimura K, Akashi M, Baba M. 2002. Induction of mucosal IgA following intravaginal administration of inactivated HIV-1-capturing nanospheres in mice. J Med Virol 66:291-298.
22. Lamm ME, Nedrud JG, Kaetzel CS, Mazanec MB. 1995. IgA and mucosal defense. APMIS 103:241-246.
23. Larsson M, Fonteneau JF, Lirvall M, Haslett P, Lifson JD, Bhardwaj N. 2002. Activation of HIV-1 specific CD4 and CD8 T cells by human dendritic cells: Roles for cross-presentation and non-infectious HIV-1 virus. AIDS 16:1319-1329.
24. Letvin NL. 1998. Progress in the development of an HIV-1 vaccine. Science 280:1875-1880.
25. Lisziewicz J, Rosenberg E, Lieberman J, Jessen H, Lopalco L, Siliciano R, Walker B, Lori F. 1999. Control of HIV despite the discontinuation of antiretroviral therapy. N Engl J Med 340:1683-1684.
26. Lori F, Hall L, Lusso P, Popovic M, Markham P, Franchini G, Reitz MS, Jr. 1992. Effect of reciprocal complementation of two defective human immunodeficiency virus type 1 (HIV-1) molecular clones on HIV-1 cell tropism and virulence. J Virol 66:5553-5560.
27. Lutz MB, Kukutsch N, Ogilvie AL, Rossner S, Koch F, Romani N, Schuler G. 1999. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods 223:77-92.
28. Mazzoli S, Trabattoni D, Caputo SL, Piconi S, Ble C, Meacci F, Ruzzante S, Salvi A, Semplici F, Longhi R, Fusi ML, Tofani N, Biasin M, Villa ML, Mazzotta F, Clerici M. 1997. HIV-specific mucosal and cellular immunity in HIV-seronegative partners of HIV-seropositive individuals. Nat Med 3:1250-1257.
29. Mazzoli S, Lopalco L, Salvi A, Trabattoni D, Caputo SL, Semplici F, Biasin M, Blé C, Cosma A, Pastori C, Meacci F, Mazzotta F, Villa ML, Siccardi AG, Clerici M. 1999. Human immunodeficiency virus (HIV)-specific IgA and HIV neutralizing activity in the serum of exposed seronegative partners of HIV-seropositive persons. J Infect Dis 180:871-875.
30. Miyake A, Akagi T, Enose Y, Ueno M, Kawamura M, Horiuchi R, Hiraishi K, Adachi M, Serizawa T, Narayan O, Akashi M, Baba M, HayamiM. 2004. Induction of HIV-specific antibody response and protection against vaginal SHIV transmission by intranasal immunization with inactivated SHIV-capturing nanospheres in macaques. J Med Virol 73:368-377.
31. Moore A, McGuirk P, Adams S, Jones WC, McGee JP, O'Hagan DT, Mills KH. 1995. Immunization with a soluble recombinant HIV protein entrapped in biodegradable microparticles induces HIV-specific CD8+ cytotoxic T lymphocytes and CD4+ Th1 cells. Vaccine 13:1741-1749.
32. Morris CB, Cheng E, Thanawastien A, Cardenas-Freytag L, Clements JD. 2000. Effectiveness of intranasal immunization with HIV-gp160 and an HIV-1 env CTL epitope peptide (E7) in combination with the mucosal adjuvant LT(R192G). Vaccine 18:1944-1951.
33. Okada E, Sasaki S, Ishii N, Aoki I, Yasuda T, Nishioka K, Fukushima J, Miyazaki J, Wahren B, Okuda K. 1997. Intranasal immunization of a DNA vaccine with IL-12- and granulocyte-macrophage colony-stimulating factor (GM-CSF)-expressing plasmids in liposomes induces strong mucosal and cell-mediated immune responses against HIV-1 antigens. J Immunol 159:3638-3647.
34. Porgador A, Staats HF, Faiola B, Gilboa E, Palker TJ. 1997. Intranasal immunization with CTL epitope peptides from HIV-1 or ovalbumin and the mucosal adjuvant cholera toxin induces peptide-specific CTLs and protection against tumor development in vivo. J Immunol 158:834-841.
35. Sato K, Yamashita N, Baba M, Matsuyama T. 2003a. Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells. Blood 101:3581-3589.
36. Sato K, Yamashita N, Yamashita N, Baba M, Matsuyama T. 2003b. Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse. Immunity 18:367-379.
37. Spira AI, Marx PA, Patterson BK, Mahoney J, Koup RA, Wolinsky SM, Ho DD. 1996. Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. J Exp Med 183:215-225.
38. Vermaelen KY, Carro-Muino I, Lambrecht BN, Pauwels RA. 2001. Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. J Exp Med 193:51-60.
39. Vremec D, Shortman K. 1997. Dendritic cell subtypes in mouse lymphoid organs: Cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes. J Immunol 159:565-573.
40. Yoshizawa I, Soda Y, Mizuochi T, Yasuda S, Rizvi TA, Mizuochi T, Takemori T, Tsunetsugu-Yokota Y. 2001. Enhancement of mucosal immune response against HIV-1 Gag by DNA immunization. Vaccine 19:2995-3003.