Radiolabeling, pharmacoscintigraphic evaluation and antiretroviral efficacy of stavudine loaded 99mTc labeled galactosylated liposomes

European Journal of Pharmaceutical Sciences

Volumn 33, Issue 3, 2008, Pages 271-281

  Garg, Minakshi ^a   Garg, Babu Ram ^b   Jain, Sanyog ^c   Mishra, Pushpa ^c   Sharma, Rakesh K ^c   Mishra, Anil K ^c   Dutta, Tathagata ^a   Jain, Narendra K ^a  

^a DR H S GOUR UNIVERSITY   (India)

^b Swami Devi Dyal Institute of Pharmacy   (India)

^c INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

99mTc; Cytotoxicity; Galactosylated liposomes; HIV; Radiolabeling; Scintigraphy; Stavudine

Indexed keywords

CHOLESTEROL; DIMYRISTOYL PHOSPHATIDYLETHANOLAMINE; GALACTOSE; LIPOSOME TC 99M; PHOSPHATIDYLCHOLINE; STANNOUS CHLORIDE; STAVUDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; DRUG ACCUMULATION; DRUG CLEARANCE; DRUG COATING; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG INHIBITION; DRUG LABELING; DRUG RETENTION; EVAPORATION; FEMALE; GAMMA SCINTIGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; ISOTOPE LABELING; LIPOSOMAL DELIVERY; LIVER; MONONUCLEAR PHAGOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SPLEEN; VIRUS CULTURE;

EID: 39749174284     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2007.12.006     Document Type: Article

References (29)

1. 99mTc-labeled liposome encapsulated cyclosporine J. Drug Target. 11 2003 187 196
2. P.R. Ashton S.E. Boyd C.L. Brown S.A. Nepogodiev E.W. Meijer H.W.I. Peerlings J.F. Stoddart Synthesis of glycodendrimers by modification of poly(propylene imine) dendrimers Chem. Eur. J. 3 1997 974 984
3. L.M. Bedoya S. Sanchez-Palomino M.J. Abad P. Bermejo J.J. Alcami Anti-HIV activity of medicinal plant extracts J. Ethnopharmacol. 77 2001 113 116
4. N. Duzgunes S. Simoes V. Slepushkin E. Pretzer D. Flasher I.I. Salem G. Steffan K. Konopka M.C. Pedroso de Lima Delivery of antiviral agents in liposomes Methods Enzymol. 391 2005 351 373
5. K.H. Elverold G.I. Nedredal A. Revhaug B. Smedsrd Scavenger properties of cultivated pig liver endothelial cell Compar. Hepatol. 3 2004 1 11
6. J. Embretson M. Zupancic J.L. Ribas A. Burke P. Racz K. Tenner-Racz A.T. Haase Massive covert infection of helper T-lymphocytes and macrophages by HIV during the incubation period of AIDS Nature 362 1993 359 362
7. Feng, M., Cai, Q., Huang, H., Zhou, P., in press. Liver targeting and anti-HBV activity of reconstituted HDL–acyclovir palmitate complex. Eur. J. Pharm. Biopharm. doi:10.1016/j.ejpb.2007.07.005 .
8. D.S. Friend D. Papahadjopoulos R.J. Debs Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes Biochim. Biophys. Acta 1278 1996 41 50
9. J.F. Gagne A. Desormeaux S. Perron M.J. Tremblay M.G. Bergeron Targeted delivery of indinavir to HIV-1 primary reservoirs with immunoliposomes Biochim. Biophys. Acta Biomemb. 558 2 2002 198 210
10. M. Garg N.K. Jain Reduced hematopoietic toxicity, enhanced cellular uptake and altered pharmacokinetics of azidothymidine loaded galactosylated liposomes J. Drug Target. 14 2006 1 11
11. M. Garg A. Asthana H.B. Agashe G.P. Agrawal N.K. Jain Stavudine-loaded mannosylated liposomes: in-vitro anti-HIV-I activity, tissue distribution and pharmacokinetics J. Pharm. Pharmacol. 58 2006 605 616
12. M. Garg T. Dutta N.K. Jain Reduced hepatic toxicity, enhanced cellular uptake and altered pharmacokinetics of stavudine loaded galactosylated liposomes Eur. J. Pharm. Biopharm. 67 2007 76 85
13. J. Haensler F. Schuber Preparation of neo-galactosylated liposomes and their interaction with mouse peritoneal macrophages Biochim. Biophys. Acta 946 1988 95 105
14. Y.J. Kao R.L. Juliano Interactions of liposomes with reticuloendothelial dystem: effects of re-blockade on the clearance of large unilamellar vesicles Biochim. Biophys. Acta 677 1991 453 461
15. A.L. Klibanov K. Maruyama A.M. Beckerleg V.P. Torchilin L. Huag Activity of amphipathic poly (ethylene glycol) 5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavourable for immunoliposome binding to target Biochim. Biophys. Acta 1062 1991 142 148
16. K. Konopka B.R. Davis C.E. Larsen D.R. Alford R.J. Debs N. Duzgunes Liposomes modulate human immunodeficiency virus infectivity J. Gen. Virol. 71 1990 2899 2907
17. J.D. Mareuil K. Mabrouk E. Doria M. Moulard S.D. Chasteigner R. Oughideni J.V. Rietschoten H. Rochat M.D. Waard J.M. Sabatier Liposomal encapsulation enhances antiviral efficacy of SPC3 against human immunodeficiency virus type-1 infection in human lymphocytes Antivir. Res. 54 3 2002 175 188
18. R.R.C. New The Liposomes: A Practical Approach 1990 Oxford University Press Oxford pp. 1–104
19. P. Opanasopit M. Sakai M. Nishikawa S. Shigeru Kawakami F. Yamashita M. Hashida Inhibition of liver metastasis by targeting of immunomodulators using mannosylated liposome carriers J. Control. Release 80 1–3 2002 283 294
20. G. Pantaleo C. Graziosi J.F. Demarest L. Butini M. Montroni C.H. Fox J.M. Orenstein D.P. Kotler A.S. Fauci HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease Nature 362 1993 355 358
21. L.H. Reddy R.K. Sharma R.S.R. Murthy Enhanced tumour uptake of doxorubicin B loaded poly (butyl cynoacrylate) nanoparticles in mice bearing Dalton's lymphoma tumors J. Drug Target. 2 2004 443 451
22. L.H. Reddy R.K. Sharma K. Chuttani A.K. Mishra R.S.R. Murthy Influence of administration route on tumour uptake and biodiatribution of etoposide loaded solid lipid nanoparticles in dalton's lymphoma tumor bearing mice J. Control. Release 105 2005 185 198
23. D. Salvatori S. Vincenzetti G. Maury G. Gosselin G. Gaubert A. Vita Maedi-Visna virus: a model for in vitro testing of potential anti-HIV drugs Compar. Immunol. Microbiol. Infect. Dis. 24 2001 113 122
24. A. Sato M. Takagi A. Shimamoto S. Kawakami M. Hashida Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice Biomaterials 28 7 2007 1434 1442
25. K. Shigeta S. Kawakami Y. Higuchi T. Okuda H. Yagi F. Yamashita M. Hashida Novel histidine-conjugated galactosylated cationic liposomes for efficient hepatocyte-selective gene transfer in human hepatoma HepG2 cells J. Control. Release 118 2 2007 262 270
26. F.C. Szoka D. Papahadjopoulos Procedure for preparation of liposomes with large aqueous space and high capture by reverse-phase evaporation Proc. Natl. Acad. Sci. U.S.A. 75 1978 4194 4198
27. H. Thakkar R.K. Sharma A.K. Mishra K. Chuttani R.S.R. Murthy Efficiency of chitosan microspheres for controlled intra-articular delivery of celecoxib in inflammed joints J. Pharm. Pharmcol. 56 2004 1091 1099
28. The Merck Index, 2001. An Encyclopedia of Chemicals, Drugs and Biologicals, 13th ed. Merck Research Laboratories, NJ, p. 1567.
29. C.L. Williams G.M. Stancel A.G. Gilman L.S. Goodman T.W. Rall F. Murad The Pharmacological Basis of Therapeutics 9th ed. 1990 Macmillan Publishing Co. New York 1205